17β-Estradiol and/or progesterone protect from insulin resistance in STZ-induced diabetic rats

Journal of Steroid Biochemistry and Molecular Biology

Volumn 111, Issue 3-5, 2008, Pages 287-294

  Ordonez P ^a   Moreno, M ^a   Alonso, A ^a   Llaneza, P ^a   Diaz F ^a   Gonzalez C ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

Author keywords

Diabetes mellitus; E2; Glucose toxicity; Insulin sensitivity; P4

Indexed keywords

ESTRADIOL; GLUCOSE TRANSPORTER 4; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROGESTERONE; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; PROTEIN SUBUNIT; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; ESTRADIOL BLOOD LEVEL; FEMALE; HORMONAL THERAPY; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; NONHUMAN; OVARIECTOMY; PROTEIN CONTENT; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STREPTOZOCIN DIABETES; TREATMENT OUTCOME; ANIMAL; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; WISTAR RAT;

RATTUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; ESTRADIOL; FEMALE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TRANSPORTER TYPE 4; INSULIN RESISTANCE; OVARIECTOMY; PROGESTERONE; PROTEIN SUBUNITS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 49449085786     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2008.07.001     Document Type: Article

References (38)

1. Rossetti L., Giaccari A., and DeFronzo R.A. Glucose toxicity. Diabetes Care 13 6 (1990) 610-630
2. Yki-Jarvinen H., Helve E., and Koivisto V.A. Hyperglycemia decreases glucose uptake in type I diabetes. Diabetes 36 8 (1987) 892-896
3. Le Marchand-Brustel Y., Gautier N., Cormont M., and Van Obberghen E. Wortmannin inhibits the action of insulin but not that of okadaic acid in skeletal muscle: comparison with fat cells. Endocrinology 136 8 (1995) 3564-3570
4. Okada T., Kawano Y., Sakakibara T., Hazeki O., and Ui M. Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes, Studies with a selective inhibitor wortmannin. J. Biol. Chem. 269 5 (1994) 3568-3573
5. Tanti J.F., Gremeaux T., Grillo S., Calleja V., Klippel A., Williams L.T., Van Obberghen E., and Le Marchand-Brustel Y. Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes. J. Biol. Chem. 271 41 (1996) 25227-25232
6. Rossetti L., Smith D., Shulman G.I., Papachristou D., and DeFronzo R.A. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J. Clin. Invest. 79 5 (1987) 1510-1515
7. Block N.E., Komori K., Dutton S.L., Robinson K.A., and Buse M.G. Skeletal muscle insulin-receptor kinase. Effects of substrate inhibition and diabetes. Diabetes 40 12 (1991) 1691-1700
8. Ordonez P., Moreno M., Alonso A., Fernandez R., Diaz F., and Gonzalez C. Insulin sensitivity in streptozotocin-induced diabetic rats treated with different doses of 17beta-oestradiol or P4. Exp. Physiol. 92 1 (2007) 241-249
9. Giorgino F., Chen J.H., and Smith R.J. Changes in tyrosine phosphorylation of insulin receptors and a 170,000 molecular weight nonreceptor protein in vivo in skeletal muscle of streptozotocin-induced diabetic rats: effects of insulin and glucose. Endocrinology 130 3 (1992) 1433-1444
10. Saad M.J., Araki E., Miralpeix M., Rothenberg P.L., White M.F., and Kahn C.R. Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance. J. Clin. Invest. 90 5 (1992) 1839-1849
11. Folli F., Saad M.J., Backer J.M., and Kahn C.R. Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus. J. Clin. Invest. 92 4 (1993) 1787-1794
12. Napoli R., Hirshman M.F., and Horton E.S. Mechanisms and time course of impaired skeletal muscle glucose transport activity in streptozocin diabetic rats. J. Clin. Invest. 96 1 (1995) 427-437
13. Klip A., Ramlal T., Bilan P.J., Cartee G.D., Gulve E.A., and Holloszy J.O. Recruitment of GLUT-4 glucose transporters by insulin in diabetic rat skeletal muscle. Biochem. Biophys. Res. Commun. 172 2 (1990) 728-736
14. Barnard R.J., Youngren J.F., Kartel D.S., and Martin D.A. Effects of streptozotocin-induced diabetes on glucose transport in skeletal muscle. Endocrinology 126 4 (1990) 1921-1926
15. Yki-Jarvinen H., and Koivisto V.A. Continuous subcutaneous insulin infusion therapy decreases insulin resistance in type 1 diabetes. J. Clin. Endocrinol. Metab. 58 4 (1984) 659-666
16. Livingstone C., and Collison M. Sex steroids and insulin resistance. Clin. Sci. (London) 102 2 (2002) 151-166
17. Wild S., Roglic G., Green A., Sicree R., and King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27 5 (2004) 1047-1053
18. Gale E.A., and Gillespie K.M. Diabetes and gender. Diabetologia 44 1 (2001) 3-15
19. Margolis K.L., Bonds D.E., Rodabough R.J., Tinker L., Phillips L.S., Allen C., Bassford T., Burke G., Torrens J., and Howard B.V. Women's Health Initiative Investigators. Effect of oestrogen plus progestin on the incidence of diabetes in postmenopausal women: results from the Women's Health Initiative Hormone Trial. Diabetologia 47 7 (2004) 1175-1187
20. Gonzalez C., Alonso A., Alvarez N., Diaz F., Martinez M., Fernandez S., and Patterson A.M. Role of 17beta-estradiol and/or P4 on insulin sensitivity in the rat: implications during pregnancy. J. Endocrinol. 166 2 (2000) 283-291
21. Gonzalez C., Alonso A., Grueso N.A., Diaz F., Esteban M.M., Fernandez S., and Patterson A.M. Role of 17beta-estradiol administration on insulin sensitivity in the rat: implications for the insulin receptor. Steroids 67 13-14 (2002) 993-1005
22. Gonzalez C., Alonso A., Diaz F., and Patterson A.M. Dose- and time-dependent effects of 17beta-oestradiol on insulin sensitivity in insulin-dependent tissues of rat: implications of IRS-1. J. Endocrinol 176 3 (2003) 367-379
23. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
24. Towbin H., Staehelin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76 9 (1979) 4350-4354
25. Hirshman M.F., Goodyear L.J., Wardzala L.J., Horton E.D., and Horton E.S. Identification of an intracellular pool of glucose transporters from basal and insulin-stimulated rat skeletal muscle. J. Biol. Chem. 265 2 (1990) 987-991
26. Yki-Jarvinen H. Glucose toxicity. Endocr. Rev. 13 3 (1992) 415-431
27. Shepherd P.R., and Kahn B.B. Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus. N. Engl. J. Med. 341 4 (1999) 248-257
28. Marette A., Dimitrakoudis D., Shi Q., Rodgers C.D., Klip A., and Vranic M. Glucose rapidly decreases plasma membrane GLUT4 content in rat skeletal muscle. Endocrine 10 1 (1999) 13-81999
29. Kanaya A.M., Herrington D., Vittinghoff E., Lin F., Grady D., Bittner V., Cauley J.A., Barrett-Connor E., and Heart. Estrogen/progestin replacement study. Glycemic effects of postmenopausal hormone therapy: the heart and estrogen/progestin replacement study. A randomized, double-blind, placebo-controlled trial. Ann. Intern. Med. 138 1 (2003) 1-9
30. DeFronzo R.A., Tobin J.D., and Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 237 3 (1979) 214-223
31. Radziuk J. Insulin sensitivity and its measurement: structural commonalities among the methods. J. Clin. Endocrinol. Metab. 85 12 (2000) 4426-4433
32. Kumagai S., Holmang A., and Bjorntorp P. The effects of oestrogen and P4 on insulin sensitivity in female rats. Acta Physiol. Scand. 149 1 (1993) 91-97
33. Ueki K., Fruman D.A., Brachmann S.M., Tseng Y.H., Cantley L.C., and Kahn C.R. Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival. Mol. Cell. Biol. 22 3 (2002) 965-977
34. Luo J., Field S.J., Lee J.Y., Engelman J.A., and Cantley L.C. The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex. J. Cell. Biol. 170 3 (2005) 455-464
35. Clark S.F., Molero J.C., and James D.E. Release of insulin receptor substrate proteins from an intracellular complex coincides with the development of insulin resistance. J. Biol. Chem. 275 6 (2000) 3819-3826
36. Pederson T.M., Kramer D.L., and Rondinone C.M. Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation. Diabetes 50 1 (2001) 24-31
37. Zhande R., Mitchell J.J., Wu J., and Sun X.J. Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1. Mol. Cell. Biol. 22 4 (2002) 1016-1026
38. Merforth S., Osmers A., and Dahlmann B. Alterations of proteasome activities in skeletal muscle tissue of diabetic rats. Mol. Biol. Rep. 26 1-2 (1999) 83-87