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Volumn 11, Issue 8, 2015, Pages 1889-1900

DNA vaccines, electroporation and their applications in cancer treatment

Author keywords

Anti tumor immunity; Cancer; DNA vaccine; Tumor immune evasion

Indexed keywords

ACID PHOSPHATASE PROSTATE ISOENZYME; ALPHA FETOPROTEIN; CARCINOEMBRYONIC ANTIGEN; CD134 ANTIGEN; CD27 ANTIGEN; CD30 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DNA VACCINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLICE INHIBITORY PROTEIN; GAMMA INTERFERON; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GLYCOPROTEIN GP 100; IMMUNOGLOBULIN; INTERLEUKIN 12; MELANOMA ANTIGEN; MONOPHENOL MONOOXYGENASE; PROSTATE SPECIFIC ANTIGEN; PROTEIN P53; SURVIVIN; TELOMERASE REVERSE TRANSCRIPTASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR ANTIGEN; CANCER VACCINE;

EID: 84938248921     PISSN: 21645515     EISSN: 2164554X     Source Type: Journal    
DOI: 10.1080/21645515.2015.1035502     Document Type: Article
Times cited : (62)

References (144)
  • 1
    • 0029913027 scopus 로고    scopus 로고
    • DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice
    • PMID:8621903
    • Kuhober A, Pudollek HP, Reifenberg K, Chisari FV, Schlicht HJ, Reimann J, Schirmbeck R. DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice. J Immunol 1996; 156:3687-95; PMID:8621903
    • (1996) J Immunol , vol.156 , pp. 3687-3695
    • Kuhober, A.1    Pudollek, H.P.2    Reifenberg, K.3    Chisari, F.V.4    Schlicht, H.J.5    Reimann, J.6    Schirmbeck, R.7
  • 3
    • 0029956512 scopus 로고    scopus 로고
    • Gene vaccination with naked plasmid DNA: Mechanism of CTL priming
    • PMID:8879229
    • Corr M, Lee DJ, Carson DA, Tighe H. Gene vaccination with naked plasmid DNA: mechanism of CTL priming. J Exp Med 1996; 184:1555-60; PMID:8879229; http://dx. doi. org/10. 1084/jem. 184. 4. 1555
    • (1996) J Exp Med , vol.184 , pp. 1555-1560
    • Corr, M.1    Lee, D.J.2    Carson, D.A.3    Tighe, H.4
  • 4
    • 0030698310 scopus 로고    scopus 로고
    • Anitigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope
    • PMID:9348305
    • Casares S, Inaba K, Brumeanu TD, Steinman RM, Bona CA. Anitigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope. J Exp Med 1997; 186:1481-6; PMID:9348305; http://dx. doi. org/10. 1084/jem. 186. 9. 1481
    • (1997) J Exp Med , vol.186 , pp. 1481-1486
    • Casares, S.1    Inaba, K.2    Brumeanu, T.D.3    Steinman, R.M.4    Bona, C.A.5
  • 5
    • 0032526344 scopus 로고    scopus 로고
    • Specific immune induction following DNAbased immunization through in vivo transfection and activation of macrophages
    • PMID:9637479
    • Chattergoon MA, Robinson TM, Boyer JD, Weiner DB. Specific immune induction following DNAbased immunization through in vivo transfection and activation of macrophages. J Immunol 1998; 160:5707-18; PMID:9637479
    • (1998) J Immunol , vol.160 , pp. 5707-5718
    • Chattergoon, M.A.1    Robinson, T.M.2    Boyer, J.D.3    Weiner, D.B.4
  • 6
    • 0030820743 scopus 로고    scopus 로고
    • Priming of cytotoxic T lymphocytes by DNA vaccines: Requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes
    • PMID:9234241
    • Fu T, Ulmer JB, Caulfield MJ, Deck RR, Friedman A, Wang S, Liu X, Donnelly JJ, Liu MA. Priming of cytotoxic T lymphocytes by DNA vaccines: requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes. Mol Med 1997; 3:362-71; PMID:9234241
    • (1997) Mol Med , vol.3 , pp. 362-371
    • Fu, T.1    Ulmer, J.B.2    Caulfield, M.J.3    Deck, R.R.4    Friedman, A.5    Wang, S.6    Liu, X.7    Donnelly, J.J.8    Liu, M.A.9
  • 7
    • 0031178797 scopus 로고    scopus 로고
    • The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites
    • PMID:9200432
    • Iwasaki A, Torres CA, Ohashi PS, Robinson HL, Barber BH. The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites. J Immunol 1997; 159:11-4; PMID:9200432
    • (1997) J Immunol , vol.159 , pp. 11-14
    • Iwasaki, A.1    Torres, C.A.2    Ohashi, P.S.3    Robinson, H.L.4    Barber, B.H.5
  • 8
    • 0029820526 scopus 로고    scopus 로고
    • DNA-based immunization by in vivo transfection of dendritic cells
    • PMID:8837611
    • Condon C, Watkins S, Celluzzi CM, Thompson K, Faldo L Jr. DNA-based immunization by in vivo transfection of dendritic cells. Nature Med 1996; 2:1122-8; PMID:8837611; http://dx. doi. org/ 10. 1038/nm1096-1122
    • (1996) Nature Med , vol.2 , pp. 1122-1128
    • Condon, C.1    Watkins, S.2    Celluzzi, C.M.3    Thompson, K.4    Faldo, L.5
  • 9
    • 33645871300 scopus 로고    scopus 로고
    • Human clinical trials of plasmid DNA vaccines
    • PMID:16291211
    • Liu M, Ulmer JB. Human clinical trials of plasmid DNA vaccines. Adv Genet 2005; 55:25-40; PMID:16291211; http://dx. doi. org/10. 1016/S0065- 2660(05)55002-8
    • (2005) Adv Genet , vol.55 , pp. 25-40
    • Liu, M.1    Ulmer, J.B.2
  • 10
    • 0029521162 scopus 로고
    • Mechanisms of lysis by cytotoxic T cells
    • PMID:8834456
    • Atkinson EA, Bleackley RC. Mechanisms of lysis by cytotoxic T cells. Crit Rev Immunol 1995; 15:359- 84; PMID:8834456; http://dx. doi. org/10. 1615/ CritRevImmunol. v15. i3-4. 90
    • (1995) Crit Rev Immunol , vol.15 , pp. 359-384
    • Atkinson, E.A.1    Bleackley, R.C.2
  • 11
    • 21944450606 scopus 로고    scopus 로고
    • Killing mechanisms of cytotoxic T lymphocytes
    • PMID:11390753
    • Groscurth P, Filgueira L. Killing mechanisms of cytotoxic T lymphocytes. News Physiol Sci 1998; 13:17- 21; PMID:11390753
    • (1998) News Physiol Sci , vol.13 , pp. 17-21
    • Groscurth, P.1    Filgueira, L.2
  • 12
    • 0036623140 scopus 로고    scopus 로고
    • Immune escape of tumors: Apoptosis resistance and tumor counterattack
    • PMID:12050175
    • Igney FH, Krammer PH. Immune escape of tumors: apoptosis resistance and tumor counterattack. J Leukoc Biol 2002; 71:907-20; PMID:12050175
    • (2002) J Leukoc Biol , vol.71 , pp. 907-920
    • Igney, F.H.1    Krammer, P.H.2
  • 18
    • 58849087222 scopus 로고    scopus 로고
    • A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3
    • PMID:19118066
    • Trimble CL, Peng S, Kos F, Gravitt P, Viscidi R, Sugar E, Pardoll D, Wu TC. A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3. Clin Cancer Res 2009; 15:361-7; PMID:19118066; http://dx. doi. org/ 10. 1158/1078-0432. CCR-08-1725
    • (2009) Clin Cancer Res , vol.15 , pp. 361-367
    • Trimble, C.L.1    Peng, S.2    Kos, F.3    Gravitt, P.4    Viscidi, R.5    Sugar, E.6    Pardoll, D.7    Wu, T.C.8
  • 20
    • 44949242538 scopus 로고    scopus 로고
    • Phase 1 trial of intranodal injection of a Melan-A/ MART-1 DNA plasmid vaccine in patients with stage IV melanoma
    • PMID:18481391
    • Weber J, Boswell W, Smith J, Hersh E, Snively J, Diaz M, Miles S, Liu X, Obrocea M, Qiu Z, et al. Phase 1 trial of intranodal injection of a Melan-A/ MART-1 DNA plasmid vaccine in patients with stage IV melanoma. J Immunother 2008; 31:215-23; PMID:18481391; http://dx. doi. org/10. 1097/CJI. 0b013e3181611420
    • (2008) J Immunother , vol.31 , pp. 215-223
    • Weber, J.1    Boswell, W.2    Smith, J.3    Hersh, E.4    Snively, J.5    Diaz, M.6    Miles, S.7    Liu, X.8    Obrocea, M.9    Qiu, Z.10
  • 21
    • 80051550377 scopus 로고    scopus 로고
    • A phase 1 study of a vaccine targeting preferentially expressed antigen in melanoma and prostate-specific membrane antigen in patients with advanced solid tumors
    • PMID:21760528
    • Weber J, Vogelzang NJ, Ernstoff MS, Goodman OB, Cranmer LD, Marshall JL, Miles S, Rosario D, Diamond DC, Qiu Z, et al. A phase 1 study of a vaccine targeting preferentially expressed antigen in melanoma and prostate-specific membrane antigen in patients with advanced solid tumors. J Immunother 2011; 34:556-67; PMID:21760528; http://dx. doi. org/ 10. 1097/CJI. 0b013e3182280db1
    • (2011) J Immunother , vol.34 , pp. 556-567
    • Weber, J.1    Vogelzang, N.J.2    Ernstoff, M.S.3    Goodman, O.B.4    Cranmer, L.D.5    Marshall, J.L.6    Miles, S.7    Rosario, D.8    Diamond, D.C.9    Qiu, Z.10
  • 22
    • 34247255391 scopus 로고    scopus 로고
    • Chemical adjuvants for plasmid DNA vaccines
    • PMID:17350735
    • Greenland J, Letvin NL. Chemical adjuvants for plasmid DNA vaccines. Vaccine 2007; 25:3731-41; PMID:17350735; http://dx. doi. org/10. 1016/j. vaccine. 2007. 01. 120
    • (2007) Vaccine , vol.25 , pp. 3731-3741
    • Greenland, J.1    Letvin, N.L.2
  • 23
    • 76749098014 scopus 로고    scopus 로고
    • DNA vaccines against infectious diseases and cancer
    • Han DJ, Weiner DB, Sin JI. DNA vaccines against infectious diseases and cancer. Biomol Ther 2010; 18:1-15; http://dx. doi. org/10. 4062/biomolther. 2010. 18. 1. 001
    • (2010) Biomol Ther , vol.18 , pp. 1-15
    • Han, D.J.1    Weiner, D.B.2    Sin, J.I.3
  • 24
  • 25
    • 84886945450 scopus 로고    scopus 로고
    • HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: Gene gun is superior to jet injector in inducing CTL responses and protective immunity
    • PMID:23264900
    • Nguyen-Hoai T, Kobelt D, Hohn O, Vu MD, Schlag PM, Dörken B, Norley S, Lipp M, Walther W, Pezzutto A, et al. HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: Gene gun is superior to jet injector in inducing CTL responses and protective immunity. Oncoimmunology 2012; 1:1537-45; PMID:23264900; http://dx. doi. org/10. 4161/onci. 22563
    • (2012) Oncoimmunology , vol.1 , pp. 1537-1545
    • Nguyen-Hoai, T.1    Kobelt, D.2    Hohn, O.3    Vu, M.D.4    Schlag, P.M.5    Dörken, B.6    Norley, S.7    Lipp, M.8    Walther, W.9    Pezzutto, A.10
  • 26
    • 10744223658 scopus 로고    scopus 로고
    • Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe
    • PMID:12922140
    • Trimble C, Lin CT, Hung CF, Pai S, Juang J, He L, Gillison M, Pardoll D, Wu L, Wu TC. Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe. Vaccine 2003; 21:4036-42; PMID:12922140; http://dx. doi. org/ 10. 1016/S0264-410X(03)00275-5
    • (2003) Vaccine , vol.21 , pp. 4036-4042
    • Trimble, C.1    Lin, C.T.2    Hung, C.F.3    Pai, S.4    Juang, J.5    He, L.6    Gillison, M.7    Pardoll, D.8    Wu, L.9    Wu, T.C.10
  • 27
    • 0032555907 scopus 로고    scopus 로고
    • Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization
    • PMID:9743526
    • Porgador A, Irvine KR, Iwasaki A, Barber BH, Restifo NP, Germain RN. Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization. J Exp Med 1998; 188:1075-82; PMID:9743526; http://dx. doi. org/10. 1084/jem. 188. 6. 1075
    • (1998) J Exp Med , vol.188 , pp. 1075-1082
    • Porgador, A.1    Irvine, K.R.2    Iwasaki, A.3    Barber, B.H.4    Restifo, N.P.5    Germain, R.N.6
  • 28
    • 68349152636 scopus 로고    scopus 로고
    • Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery
    • PMID:19622402
    • Best S, Peng S, Juang CM, Hung CF, Hannaman D, Saunders JR, Wu TC, Pai SI. Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery. Vaccine 2009; 27:5450-9; PMID:19622402; http:// dx. doi. org/10. 1016/j. vaccine. 2009. 07. 005
    • (2009) Vaccine , vol.27 , pp. 5450-5459
    • Best, S.1    Peng, S.2    Juang, C.M.3    Hung, C.F.4    Hannaman, D.5    Saunders, J.R.6    Wu, T.C.7    Pai, S.I.8
  • 29
    • 0031753867 scopus 로고    scopus 로고
    • Gene transfer into muscle by electroporation in vivo
    • PMID:9743122
    • Aihara H, Miyazaki J. Gene transfer into muscle by electroporation in vivo. Nat Biotechnol 1998; 16:867-70; PMID:9743122; http://dx. doi. org/ 10. 1038/nbt0998-867
    • (1998) Nat Biotechnol , vol.16 , pp. 867-870
    • Aihara, H.1    Miyazaki, J.2
  • 31
    • 14844291308 scopus 로고    scopus 로고
    • Gene expression and immune response kinetics using electroporation-mediated DNA delivery to muscle
    • PMID:15515140
    • Gronevik E, von Steyern FV, Kalhovde JM, Tjelle TE, Mathiesen I. Gene expression and immune response kinetics using electroporation-mediated DNA delivery to muscle. J Gene Med 2005; 7:218-27; PMID:15515140; http://dx. doi. org/ 10. 1002/jgm. 650
    • (2005) J Gene Med , vol.7 , pp. 218-227
    • Gronevik, E.1    von Steyern, F.V.2    Kalhovde, J.M.3    Tjelle, T.E.4    Mathiesen, I.5
  • 32
    • 0034283956 scopus 로고    scopus 로고
    • Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice
    • PMID:10946318
    • Dupuis M, Denis-Mize K, Woo C, Goldbeck C, Selby MJ, Chen M, Otten GR, Ulmer JB, Donnelly JJ, Ott G, et al. Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice. J Immunol 2000; 165:2850-8; PMID:10946318; http://dx. doi. org/10. 4049/ jimmunol. 165. 5. 2850
    • (2000) J Immunol , vol.165 , pp. 2850-2858
    • Dupuis, M.1    Denis-Mize, K.2    Woo, C.3    Goldbeck, C.4    Selby, M.J.5    Chen, M.6    Otten, G.R.7    Ulmer, J.B.8    Donnelly, J.J.9    Ott, G.10
  • 33
    • 43849104724 scopus 로고    scopus 로고
    • In vivo electroporation enhances the immunogenicity of hepatitis C virus nonstructural 3/ 4A DNA by increased local DNA uptake, protein expression, inflammation, and infiltration of CD3+ T cells
    • Ahlén G, Söderholm J, Tjelle T, Kjeken R, Frelin L, Höglund U, Blomberg P, Fons M, Mathiesen I, Sällberg M. In vivo electroporation enhances the immunogenicity of hepatitis C virus nonstructural 3/ 4A DNA by increased local DNA uptake, protein expression, inflammation, and infiltration of CD3+ T cells. J Immunol 2007; 179:4741-53; http://dx. doi. org/10. 4049/jimmunol. 179. 7. 4741
    • (2007) J Immunol , vol.179 , pp. 4741-4753
    • Ahlén, G.1    Söderholm, J.2    Tjelle, T.3    Kjeken, R.4    Frelin, L.5    Höglund, U.6    Blomberg, P.7    Fons, M.8    Mathiesen, I.9    Sällberg, M.10
  • 36
    • 0036594813 scopus 로고    scopus 로고
    • IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16. F10 melanoma
    • Lucas ML, Heller L, Coppola D, Heller R. IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16. F10 melanoma. Mol Ther 2002; 5:668-75
    • (2002) Mol Ther , vol.5 , pp. 668-675
    • Lucas, M.L.1    Heller, L.2    Coppola, D.3    Heller, R.4
  • 37
    • 33748571952 scopus 로고    scopus 로고
    • Regression of subcutaneous B16 melanoma tumors after intratumoral delivery of an IL-15-expressing plasmid followed by in vivo electroporation
    • PMID:16763607
    • Ugen KE, Kutzler MA, Marrero B, Westover J, Coppola D, Weiner DB, Heller R. Regression of subcutaneous B16 melanoma tumors after intratumoral delivery of an IL-15-expressing plasmid followed by in vivo electroporation. Cancer Gene Ther 2006; 13:969-74; PMID:16763607; http://dx. doi. org/ 10. 1038/sj. cgt. 7700973
    • (2006) Cancer Gene Ther , vol.13 , pp. 969-974
    • Ugen, K.E.1    Kutzler, M.A.2    Marrero, B.3    Westover, J.4    Coppola, D.5    Weiner, D.B.6    Heller, R.7
  • 40
    • 84869797481 scopus 로고    scopus 로고
    • Electroporation driven delivery of both an IL-12 expressing plasmid and cisplatin synergizes to inhibit B16 melanoma tumor growth through an NK cell mediated tumor killing mechanism
    • PMID:23151450
    • Kim H, Sin JI. Electroporation driven delivery of both an IL-12 expressing plasmid and cisplatin synergizes to inhibit B16 melanoma tumor growth through an NK cell mediated tumor killing mechanism. Hum Vaccin Immunother 2012; 8:1714-21; PMID:23151450; http://dx. doi. org/10. 4161/ hv. 22346
    • (2012) Hum Vaccin Immunother , vol.8 , pp. 1714-1721
    • Kim, H.1    Sin, J.I.2
  • 41
    • 25444459127 scopus 로고    scopus 로고
    • Both antigen optimization and lysosomal targeting are required for enhanced anti-tumour protective immunity in a human papillomavirus E7- expressing animal tumour model
    • Kim MS, Sin JI. Both antigen optimization and lysosomal targeting are required for enhanced anti-tumour protective immunity in a human papillomavirus E7- expressing animal tumour model. Immunol 2005; 116:255-66; http://dx. doi. org/10. 1111/j. 1365- 2567. 2005. 02219. x
    • (2005) Immunol , vol.116 , pp. 255-266
    • Kim, M.S.1    Sin, J.I.2
  • 42
    • 0035077790 scopus 로고    scopus 로고
    • Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen
    • PMID:11313814
    • Hsu KF, Hung CF, Cheng WF, He L, Slater LA, Ling M, Wu TC. Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen. Gene Ther 2001; 8:376-83; PMID:11313814; http://dx. doi. org/ 10. 1038/sj. gt. 3301408
    • (2001) Gene Ther , vol.8 , pp. 376-383
    • Hsu, K.F.1    Hung, C.F.2    Cheng, W.F.3    He, L.4    Slater, L.A.5    Ling, M.6    Wu, T.C.7
  • 43
    • 57649210510 scopus 로고    scopus 로고
    • Induction of antitumor immunity in vivo following delivery of a novel HPV-16 DNA vaccine encoding an E6/E7 fusion antigen
    • PMID:19022315
    • Yan J, Reichenbach DK, Corbitt N, Hokey DA, Ramanathan MP, McKinney KA, Weiner DB, Sewell D. Induction of antitumor immunity in vivo following delivery of a novel HPV-16 DNA vaccine encoding an E6/E7 fusion antigen. Vaccine 2009; 27:431-40; PMID:19022315; http://dx. doi. org/10. 1016/j. vaccine. 2008. 10. 078
    • (2009) Vaccine , vol.27 , pp. 431-440
    • Yan, J.1    Reichenbach, D.K.2    Corbitt, N.3    Hokey, D.A.4    Ramanathan, M.P.5    McKinney, K.A.6    Weiner, D.B.7    Sewell, D.8
  • 44
    • 70350128929 scopus 로고    scopus 로고
    • DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer
    • PMID:19619001
    • Low L, Mander A, McCann K, Dearnaley D, Tjelle T, Mathiesen I, Stevenson F, Ottensmeier CH. DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer. Hum Gene Ther 2009; 20:1269-78; PMID:19619001; http://dx. doi. org/10. 1089/ hum. 2009. 067
    • (2009) Hum Gene Ther , vol.20 , pp. 1269-1278
    • Low, L.1    Mander, A.2    McCann, K.3    Dearnaley, D.4    Tjelle, T.5    Mathiesen, I.6    Stevenson, F.7    Ottensmeier, C.H.8
  • 45
    • 84871011037 scopus 로고    scopus 로고
    • DNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8(+) T-cell responses and increases PSA doubling time
    • PMID:22729556
    • Chudley L, McCann K, Mander A, Tjelle T, Campos- Perez J, Godeseth R, Creak A, Dobbyn J, Johnson B, Bass P, et al. DNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8(+) T-cell responses and increases PSA doubling time. Cancer Immunol Immunother 2012; 61:2161-70; PMID:22729556; http://dx. doi. org/10. 1007/s00262- 012-1270-0
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 2161-2170
    • Chudley, L.1    McCann, K.2    Mander, A.3    Tjelle, T.4    Campos-Perez, J.5    Godeseth, R.6    Creak, A.7    Dobbyn, J.8    Johnson, B.9    Bass, P.10
  • 46
    • 0037884716 scopus 로고    scopus 로고
    • A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen
    • PMID:12734366
    • Gold JS, Ferrone CR, Guevara-Patiño JA, Hawkins WG, Dyall R, Engelhorn ME, Wolchok JD, Lewis JJ, Houghton AN. A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen. J Immunol 2003; 170:5188-94; PMID:12734366; http://dx. doi. org/10. 4049/jimmunol. 170. 10. 5188
    • (2003) J Immunol , vol.170 , pp. 5188-5194
    • Gold, J.S.1    Ferrone, C.R.2    Guevara-Patiño, J.A.3    Hawkins, W.G.4    Dyall, R.5    Engelhorn, M.E.6    Wolchok, J.D.7    Lewis, J.J.8    Houghton, A.N.9
  • 49
    • 66849135251 scopus 로고    scopus 로고
    • Cancer immunotherapy: Co-stimulatory agonists and co-inhibitory antagonists
    • PMID:19659765
    • Peggs KS, Quezada SA, Allison JP. Cancer immunotherapy: co-stimulatory agonists and co-inhibitory antagonists. Clin Exp Immunol 2009; 157:9-19; PMID:19659765; http://dx. doi. org/10. 1111/j. 1365- 2249. 2009. 03912. x
    • (2009) Clin Exp Immunol , vol.157 , pp. 9-19
    • Peggs, K.S.1    Quezada, S.A.2    Allison, J.P.3
  • 50
    • 65349083187 scopus 로고    scopus 로고
    • Negative regulators of T-cell activation: Potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections
    • PMID:19426215
    • Pentcheva-Hoang T, Corse E, Allison JP. Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections. Immunol Rev 2009; 229:67-87; PMID:19426215; http://dx. doi. org/ 10. 1111/j. 1600-065X. 2009. 00763. x
    • (2009) Immunol Rev , vol.229 , pp. 67-87
    • Pentcheva-Hoang, T.1    Corse, E.2    Allison, J.P.3
  • 51
    • 84873100024 scopus 로고    scopus 로고
    • Combined stimulation of TLR9 and 4. 1BB augments Trp2 peptide vaccine-mediated melanoma rejection by increasing Ag-specific CTLs and their infiltration into tumor sites
    • PMID:23219755
    • Sin JI, Kim H, Ahn E, Jeon YH, Park WS, Lee SY, Kwon B. Combined stimulation of TLR9 and 4. 1BB augments Trp2 peptide vaccine-mediated melanoma rejection by increasing Ag-specific CTLs and their infiltration into tumor sites. Cancer Lett 2013; 330:190-9; PMID:23219755; http://dx. doi. org/ 10. 1016/j. canlet. 2012. 11. 045
    • (2013) Cancer Lett , vol.330 , pp. 190-199
    • Sin, J.I.1    Kim, H.2    Ahn, E.3    Jeon, Y.H.4    Park, W.S.5    Lee, S.Y.6    Kwon, B.7
  • 52
    • 84896718228 scopus 로고    scopus 로고
    • Combined stimulation of IL- 2 and 4-1BB receptors augments the antitumor activity of E7 DNA vaccines by increasing Ag-specific CTL responses
    • PMID:24391824
    • Kim H, Kwon B, Sin JI. Combined stimulation of IL- 2 and 4-1BB receptors augments the antitumor activity of E7 DNA vaccines by increasing Ag-specific CTL responses. PLoS One 2013; 8:e83765; PMID:24391824; http://dx. doi. org/10. 1371/journal. pone. 0083765
    • (2013) PLoS One , vol.8
    • Kim, H.1    Kwon, B.2    Sin, J.I.3
  • 53
    • 23944461007 scopus 로고    scopus 로고
    • Vaccination with dendritic cells pulsed with apoptotic tumors in combination with anti-OX40 and anti-4-1BB monoclonal antibodies induces T cell-mediated protective immunity in Her-2/neu transgenic mice
    • PMID:15856473
    • Cuadros C, Dominguez AL, Lollini PL, Croft M, Mittler RS, Borgström P, Lustgarten J. Vaccination with dendritic cells pulsed with apoptotic tumors in combination with anti-OX40 and anti-4-1BB monoclonal antibodies induces T cell-mediated protective immunity in Her-2/neu transgenic mice. Int J Cancer 2005; 116:934-43; PMID:15856473; http://dx. doi. org/10. 1002/ijc. 21098
    • (2005) Int J Cancer , vol.116 , pp. 934-943
    • Cuadros, C.1    Dominguez, A.L.2    Lollini, P.L.3    Croft, M.4    Mittler, R.S.5    Borgström, P.6    Lustgarten, J.7
  • 55
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • PMID:10430624
    • van Elsas A, Hurwitz AA, Allison JP. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 1999; 190:355-66; PMID:10430624; http://dx. doi. org/ 10. 1084/jem. 190. 3. 355
    • (1999) J Exp Med , vol.190 , pp. 355-366
    • van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 56
    • 33745851479 scopus 로고    scopus 로고
    • CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
    • PMID:16778987
    • Quezada SA, Peggs KS, Curran MA, Allison JP. CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells. J Clin Invest 2006; 116:1935- 45; PMID:16778987; http://dx. doi. org/10. 1172/ JCI27745
    • (2006) J Clin Invest , vol.116 , pp. 1935-1945
    • Quezada, S.A.1    Peggs, K.S.2    Curran, M.A.3    Allison, J.P.4
  • 57
    • 11144353596 scopus 로고    scopus 로고
    • CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems
    • PMID:15068853
    • Gregor PD, Wolchok JD, Ferrone CR, Buchinshky H, Guevara-Patiño JA, Perales MA, Mortazavi F, Bacich D, Heston W, Latouche JB, et al. CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems. Vaccine 2004; 22:1700-8; PMID:15068853; http://dx. doi. org/10. 1016/j. vaccine. 2003. 10. 048
    • (2004) Vaccine , vol.22 , pp. 1700-1708
    • Gregor, P.D.1    Wolchok, J.D.2    Ferrone, C.R.3    Buchinshky, H.4    Guevara-Patiño, J.A.5    Perales, M.A.6    Mortazavi, F.7    Bacich, D.8    Heston, W.9    Latouche, J.B.10
  • 60
    • 12344338245 scopus 로고    scopus 로고
    • Induction of PSA-specific CTLs and anti-tumor immunity by a genetic prostate cancer vaccine
    • PMID:15389792
    • Roos AK, Pavlenko M, Charo J, Egevad L, Pisa P. Induction of PSA-specific CTLs and anti-tumor immunity by a genetic prostate cancer vaccine. Prostate 2005; 62:217-23; PMID:15389792; http://dx. doi. org/10. 1002/pros. 20135
    • (2005) Prostate , vol.62 , pp. 217-223
    • Roos, A.K.1    Pavlenko, M.2    Charo, J.3    Egevad, L.4    Pisa, P.5
  • 61
    • 0033780172 scopus 로고    scopus 로고
    • IL-12 plasmidenhanced DNA vaccination against carcinoembryonic antigen (CEA) studied in immune-gene knockout mice
    • PMID:11021590
    • Song K, Chang Y, Prud'homme GJ. IL-12 plasmidenhanced DNA vaccination against carcinoembryonic antigen (CEA) studied in immune-gene knockout mice. Gene Ther 2000; 7:1527-35; PMID:11021590; http://dx. doi. org/10. 1038/sj. gt. 3301274
    • (2000) Gene Ther , vol.7 , pp. 1527-1535
    • Song, K.1    Chang, Y.2    Prud'homme, G.J.3
  • 62
    • 68249142911 scopus 로고    scopus 로고
    • Suppression of antitumor protective cytotoxic T lymphocyte responses to a human papillomavirus 16 E7 DNA vaccine by coinjection of interleukin-12 cDNA: Involvement of nitric oxide in immune suppression
    • PMID:19740332
    • Sin JI. Suppression of antitumor protective cytotoxic T lymphocyte responses to a human papillomavirus 16 E7 DNA vaccine by coinjection of interleukin-12 cDNA: involvement of nitric oxide in immune suppression. Immunology 2009; 128:e707-e17; PMID:19740332; http://dx. doi. org/10. 1111/j. 1365- 2567. 2009. 03068. x
    • (2009) Immunology , vol.128 , pp. 707-717
    • Sin, J.I.1
  • 63
    • 84919460653 scopus 로고    scopus 로고
    • A loss of antitumor therapeutic activity of CEA DNA vaccines is associated with the lack of tumor cells' antigen presentation to Ag-specific CTLs in a colon cancer model
    • PMID:25449428
    • Ahn E, Kim H, Han KT, Sin JI. A loss of antitumor therapeutic activity of CEA DNA vaccines is associated with the lack of tumor cells' antigen presentation to Ag-specific CTLs in a colon cancer model. Cancer Lett 2015; 356:676-85; PMID:25449428; http://dx. doi. org/10. 1016/j. canlet. 2014. 10. 019
    • (2015) Cancer Lett , vol.356 , pp. 676-685
    • Ahn, E.1    Kim, H.2    Han, K.T.3    Sin, J.I.4
  • 64
    • 0042964824 scopus 로고    scopus 로고
    • Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins
    • PMID:12840065
    • Kim TW, Hung CF, Ling M, Juang J, He L, Hardwick JM, Kumar S, Wu TC. Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. J Clin Invest 2003; 112:109-17; PMID:12840065; http://dx. doi. org/10. 1172/ JCI200317293
    • (2003) J Clin Invest , vol.112 , pp. 109-117
    • Kim, T.W.1    Hung, C.F.2    Ling, M.3    Juang, J.4    He, L.5    Hardwick, J.M.6    Kumar, S.7    Wu, T.C.8
  • 65
    • 1642453782 scopus 로고    scopus 로고
    • Enhancement of DNA vaccine potency by coadministration of a tumor antigen gene and DNA encoding serine protease inhibitor-6
    • PMID:14729651
    • Kim TW, Hung CF, Boyd DA, He L, Lin CT, Kaiserman D, Bird PI, Wu TC. Enhancement of DNA vaccine potency by coadministration of a tumor antigen gene and DNA encoding serine protease inhibitor-6. Cancer Res 2004; 64:400-5; PMID:14729651; http://dx. doi. org/10. 1158/0008-5472. CAN-03-1475
    • (2004) Cancer Res , vol.64 , pp. 400-405
    • Kim, T.W.1    Hung, C.F.2    Boyd, D.A.3    He, L.4    Lin, C.T.5    Kaiserman, D.6    Bird, P.I.7    Wu, T.C.8
  • 66
    • 56749170720 scopus 로고    scopus 로고
    • Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma
    • PMID:18797450
    • Perales MA, Yuan J, Powel S, Gallardo HF, Rasalan TS, Gonzalez C, Manukian G, Wang J, Zhang Y, Chapman PB, et al. Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma. Mol Ther 2008; 16:2022-9; PMID:18797450; http://dx. doi. org/ 10. 1038/mt. 2008. 196
    • (2008) Mol Ther , vol.16 , pp. 2022-2029
    • Perales, M.A.1    Yuan, J.2    Powel, S.3    Gallardo, H.F.4    Rasalan, T.S.5    Gonzalez, C.6    Manukian, G.7    Wang, J.8    Zhang, Y.9    Chapman, P.B.10
  • 68
    • 26444556446 scopus 로고    scopus 로고
    • Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA
    • PMID:15906358
    • Mennuni C, Calvaruso F, Facciabene A, Aurisicchio L, Storto M, Scarselli E, Ciliberto G, La Monica N. Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA. Int J Cancer 2005; 117:444-55; PMID:15906358; http://dx. doi. org/ 10. 1002/ijc. 21188
    • (2005) Int J Cancer , vol.117 , pp. 444-455
    • Mennuni, C.1    Calvaruso, F.2    Facciabene, A.3    Aurisicchio, L.4    Storto, M.5    Scarselli, E.6    Ciliberto, G.7    La Monica, N.8
  • 69
    • 30744442807 scopus 로고    scopus 로고
    • DNA and adenoviral vectors encoding carcinoembryonic antigen fused to immunoenhancing sequences augment antigen-specific immune response and confer tumor protection
    • PMID:16409127
    • Facciabene A, Aurisicchio L, Elia L, Palombo F, Mennuni C, Ciliberto G, La Monica N. DNA and adenoviral vectors encoding carcinoembryonic antigen fused to immunoenhancing sequences augment antigen-specific immune response and confer tumor protection. Hum Gene Ther 2006; 17:81-92; PMID:16409127; http://dx. doi. org/10. 1089/hum. 2006. 17. 81
    • (2006) Hum Gene Ther , vol.17 , pp. 81-92
    • Facciabene, A.1    Aurisicchio, L.2    Elia, L.3    Palombo, F.4    Mennuni, C.5    Ciliberto, G.6    La Monica, N.7
  • 70
    • 84874978904 scopus 로고    scopus 로고
    • Phase 1 studies of the safety and immunogenicity of electroporated HER2/ CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors
    • PMID:23497415
    • Diaz-Montero CM, Chiappori A, Aurisicchio L, Bagchi A, Clark J, Dubey S, Fridman A, Fabregas JC, Marshall J, Scarselli E, et al. Phase 1 studies of the safety and immunogenicity of electroporated HER2/ CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors. J Transl Med 2013; 11:62; PMID:23497415; http://dx. doi. org/10. 1186/1479-5876-11-62
    • (2013) J Transl Med , vol.11 , pp. 62
    • Diaz-Montero, C.M.1    Chiappori, A.2    Aurisicchio, L.3    Bagchi, A.4    Clark, J.5    Dubey, S.6    Fridman, A.7    Fabregas, J.C.8    Marshall, J.9    Scarselli, E.10
  • 71
    • 33749827717 scopus 로고    scopus 로고
    • Vaccination with liposome- DNA complexes elicits enhanced antitumor immunity
    • PMID:16841080
    • U'Ren L, Kedl R, Dow S. Vaccination with liposome- DNA complexes elicits enhanced antitumor immunity. Cancer Gene Ther 2006; 13:1033-44; PMID:16841080; http://dx. doi. org/10. 1038/sj. cgt. 7700982
    • (2006) Cancer Gene Ther , vol.13 , pp. 1033-1044
    • U'Ren, L.1    Kedl, R.2    Dow, S.3
  • 72
    • 78449236912 scopus 로고    scopus 로고
    • The use of layered double hydroxides as DNA vaccine delivery vector for enhancement of anti-melanoma immune response
    • PMID:20934217
    • Li A, Qin L, Wang W, Zhu R, Yu Y, Liu H, Wang S. The use of layered double hydroxides as DNA vaccine delivery vector for enhancement of anti-melanoma immune response. Biomaterials 2011; 32:469-77; PMID:20934217; http://dx. doi. org/10. 1016/j. biomaterials. 2010. 08. 107
    • (2011) Biomaterials , vol.32 , pp. 469-477
    • Li, A.1    Qin, L.2    Wang, W.3    Zhu, R.4    Yu, Y.5    Liu, H.6    Wang, S.7
  • 73
    • 37549036729 scopus 로고    scopus 로고
    • Survivin, cancer networks and pathwaydirected drug discovery
    • PMID:18075512
    • Altieri DC. Survivin, cancer networks and pathwaydirected drug discovery. Nat Rev Cancer 2008; 8:61- 70; PMID:18075512; http://dx. doi. org/10. 1038/ nrc2293
    • (2008) Nat Rev Cancer , vol.8 , pp. 61-70
    • Altieri, D.C.1
  • 75
    • 0037650159 scopus 로고    scopus 로고
    • Telomerase as tumor marker
    • PMID:12757980
    • Hiyama E, Hiyama K. Telomerase as tumor marker. Cancer Lett 2003; 194:221-33; PMID:12757980; http://dx. doi. org/10. 1016/S0304-3835(02)00709-7
    • (2003) Cancer Lett , vol.194 , pp. 221-233
    • Hiyama, E.1    Hiyama, K.2
  • 76
    • 84867575801 scopus 로고    scopus 로고
    • DNA and adenovirus tumor vaccine expressing truncated survivin generates specific immune responses and anti-tumor effects in a murine melanoma model
    • PMID:22706381
    • Zhang H, Wang Y, Liu C, Zhang L, Xia Q, Zhang Y, Wu J, Jiang C, Chen Y, Wu Y, et al. DNA and adenovirus tumor vaccine expressing truncated survivin generates specific immune responses and anti-tumor effects in a murine melanoma model. Cancer Immunol Immunother 2012; 61:1857-67; PMID:22706381; http://dx. doi. org/10. 1007/s00262- 012-1296-3
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 1857-1867
    • Zhang, H.1    Wang, Y.2    Liu, C.3    Zhang, L.4    Xia, Q.5    Zhang, Y.6    Wu, J.7    Jiang, C.8    Chen, Y.9    Wu, Y.10
  • 77
    • 84921910273 scopus 로고    scopus 로고
    • Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity
    • PMID:24777680
    • Yan J, Pankhong P, Shin TH, Obeng-Adjei N, Morrow MP, Walters JN, Khan AS, Sardesai NY, Weiner DB. Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity. Cancer Immunol Res 2013; 1:179- 89; PMID:24777680; http://dx. doi. org/10. 1158/ 2326-6066. CIR-13-0001
    • (2013) Cancer Immunol Res , vol.1 , pp. 179-189
    • Yan, J.1    Pankhong, P.2    Shin, T.H.3    Obeng-Adjei, N.4    Morrow, M.P.5    Walters, J.N.6    Khan, A.S.7    Sardesai, N.Y.8    Weiner, D.B.9
  • 79
    • 0023679092 scopus 로고
    • The carcinoembryonic antigen gene family: Structure, expression and evolution
    • Thompson J, Zimmermann W. The carcinoembryonic antigen gene family: structure, expression and evolution. Tumor Biol 1988; 9:63-83; http://dx. doi. org/10. 1159/000217547
    • (1988) Tumor Biol , vol.9 , pp. 63-83
    • Thompson, J.1    Zimmermann, W.2
  • 80
    • 0026048664 scopus 로고
    • Carcinoembryonic antigen gene family: Molecular biology and clinical perspectives
    • PMID:1941355
    • Thompson JA, Grunert F, Zimmermann W. Carcinoembryonic antigen gene family: molecular biology and clinical perspectives. J Clin Lab Anal 1991; 5:344-66; PMID:1941355; http://dx. doi. org/ 10. 1002/jcla. 1860050510
    • (1991) J Clin Lab Anal , vol.5 , pp. 344-366
    • Thompson, J.A.1    Grunert, F.2    Zimmermann, W.3
  • 82
    • 0034103589 scopus 로고    scopus 로고
    • Regulation of Thelper- 1 versus T-helper-2 activity and enhancement of tumor immunity by combined DNA-based vaccination and nonviral cytokine gene transfer
    • PMID:10757021
    • Song K, Chang Y, Prud'homme GJ. Regulation of Thelper- 1 versus T-helper-2 activity and enhancement of tumor immunity by combined DNA-based vaccination and nonviral cytokine gene transfer. Gene Ther 2000; 7:481-92; PMID:10757021; http://dx. doi. org/10. 1038/sj. gt. 3301123
    • (2000) Gene Ther , vol.7 , pp. 481-492
    • Song, K.1    Chang, Y.2    Prud'homme, G.J.3
  • 83
    • 84893592971 scopus 로고    scopus 로고
    • Immunogenicity and therapeutic efficacy of a dual-component genetic cancer vaccine cotargeting carcinoembryonic antigen and HER2/neu in preclinical models
    • PMID:24195644
    • Aurisicchio L, Peruzzi D, Koo G, Wei WZ, La Monica N, Ciliberto G. Immunogenicity and therapeutic efficacy of a dual-component genetic cancer vaccine cotargeting carcinoembryonic antigen and HER2/neu in preclinical models. Hum Gene Ther 2014; 25:121- 31; PMID:24195644; http://dx. doi. org/10. 1089/ hum. 2013. 103
    • (2014) Hum Gene Ther , vol.25 , pp. 121-131
    • Aurisicchio, L.1    Peruzzi, D.2    Koo, G.3    Wei, W.Z.4    La Monica, N.5    Ciliberto, G.6
  • 84
    • 0018336222 scopus 로고
    • α-Fetoprotein in cancer and fetal development
    • PMID:89800
    • Ruoslahti E, Seppälä M. α-Fetoprotein in cancer and fetal development. Adv Cancer Res 1979; 29:275- 346; PMID:89800; http://dx. doi. org/10. 1016/ S0065-230X(08)60849-0
    • (1979) Adv Cancer Res , vol.29 , pp. 275-346
    • Ruoslahti, E.1    Seppälä, M.2
  • 86
    • 84899635997 scopus 로고    scopus 로고
    • Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients
    • PMID:24708667
    • Butterfield L, Economou JS, Gamblin TC, Geller DA. Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients. J Transl Med 2014; 12:86; PMID:24708667; http://dx. doi. org/10. 1186/1479- 5876-12-86
    • (2014) J Transl Med , vol.12 , pp. 86
    • Butterfield, L.1    Economou, J.S.2    Gamblin, T.C.3    Geller, D.A.4
  • 89
    • 1342309586 scopus 로고    scopus 로고
    • WT1 is a tumor-associated antigen in colon cancer that can be recognized by in vitro stimulated cytotoxic T cells
    • PMID:14961577
    • Koesters R, Linnebacher M, Coy JF, Germann A, Schwitalle Y, Findeisen P, von Knebel Doeberitz M. WT1 is a tumor-associated antigen in colon cancer that can be recognized by in vitro stimulated cytotoxic T cells. Int J Cancer 2004; 109:385-92; PMID:14961577; http://dx. doi. org/10. 1002/ ijc. 11721
    • (2004) Int J Cancer , vol.109 , pp. 385-392
    • Koesters, R.1    Linnebacher, M.2    Coy, J.F.3    Germann, A.4    Schwitalle, Y.5    Findeisen, P.6    von Knebel Doeberitz, M.7
  • 92
    • 0034039983 scopus 로고    scopus 로고
    • Prostate specific antigen only progression of prostate cancer
    • PMID:10799151
    • Moul JW. Prostate specific antigen only progression of prostate cancer. J Urol 2000; 163:1632-42; PMID:10799151; http://dx. doi. org/10. 1016/S0022- 5347(05)67511-8
    • (2000) J Urol , vol.163 , pp. 1632-1642
    • Moul, J.W.1
  • 93
    • 0141857763 scopus 로고    scopus 로고
    • Expression of prostate specific membrane antigen and three alternatively spliced variants of PSMA in prostate cancer patients
    • PMID:12949815
    • Schmittgen TD, Teske S, Vessella RL, True LD, Zakrajsek BA. Expression of prostate specific membrane antigen and three alternatively spliced variants of PSMA in prostate cancer patients. Int J Cancer 2003; 107:323-9; PMID:12949815; http://dx. doi. org/ 10. 1002/ijc. 11402
    • (2003) Int J Cancer , vol.107 , pp. 323-329
    • Schmittgen, T.D.1    Teske, S.2    Vessella, R.L.3    True, L.D.4    Zakrajsek, B.A.5
  • 94
    • 0000056827 scopus 로고
    • An acid phosphatase in the serum of patients with metastasizing carcinoma of the prostate gland
    • PMID:16694594
    • Gutman AB, Gutman EB. An acid phosphatase in the serum of patients with metastasizing carcinoma of the prostate gland. J Clin Invest 1938; 17; PMID:16694594; http://dx. doi. org/10. 1172/ JCI100974
    • (1938) J Clin Invest , vol.17
    • Gutman, A.B.1    Gutman, E.B.2
  • 98
    • 70249126960 scopus 로고    scopus 로고
    • Safety and immunological efficacy of a DNA vaccine encoding prostatic acid phosphatase in patients with stage D0 prostate cancer
    • PMID:19636017
    • McNeel DG, Dunphy EJ, Davies JG, Frye TP, Johnson LE, Staab MJ, Horvath DL, Straus J, Alberti D, Marnocha R, et al. Safety and immunological efficacy of a DNA vaccine encoding prostatic acid phosphatase in patients with stage D0 prostate cancer. J Clin Oncol 2009; 27:4047-54; PMID:19636017; http:// dx. doi. org/10. 1200/JCO. 2008. 19. 9968
    • (2009) J Clin Oncol , vol.27 , pp. 4047-4054
    • McNeel, D.G.1    Dunphy, E.J.2    Davies, J.G.3    Frye, T.P.4    Johnson, L.E.5    Staab, M.J.6    Horvath, D.L.7    Straus, J.8    Alberti, D.9    Marnocha, R.10
  • 99
    • 77954951895 scopus 로고    scopus 로고
    • DNA vaccine encoding prostatic acid phosphatase (PAP) elicits long-term T-cell responses in patients with recurrent prostate cancer
    • PMID:20551832
    • Becker JT, Olson BM, Johnson LE, Davies JG, Dunphy EJ, McNeel DG. DNA vaccine encoding prostatic acid phosphatase (PAP) elicits long-term T-cell responses in patients with recurrent prostate cancer. J Immunother 2010; 33:639-47; PMID:20551832; http://dx. doi. org/10. 1097/CJI. 0b013e3181dda23e
    • (2010) J Immunother , vol.33 , pp. 639-647
    • Becker, J.T.1    Olson, B.M.2    Johnson, L.E.3    Davies, J.G.4    Dunphy, E.J.5    McNeel, D.G.6
  • 100
    • 33646832055 scopus 로고    scopus 로고
    • Expression of the MAGE-A4 and NYESO- 1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma and their prognostic significance
    • PMID:16596224
    • Yoshida N, Abe H, Ohkuri T, Wakita D, Sato M, Noguchi D, Miyamoto M, Morikawa T, Kondo S, Ikeda H, et al. Expression of the MAGE-A4 and NYESO- 1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma and their prognostic significance. Int J Oncol 2006; 28:1089-98; PMID:16596224
    • (2006) Int J Oncol , vol.28 , pp. 1089-1098
    • Yoshida, N.1    Abe, H.2    Ohkuri, T.3    Wakita, D.4    Sato, M.5    Noguchi, D.6    Miyamoto, M.7    Morikawa, T.8    Kondo, S.9    Ikeda, H.10
  • 101
    • 22244454703 scopus 로고    scopus 로고
    • Heat shock protein 70/ MAGE-3 fusion protein vaccine can enhance cellular and humoral immune responses to MAGE-3 in vivo
    • PMID:15756604
    • Ma J, Sui YF, Ye J, Huang YY, Li ZS, Chen GS, Qu P, Song HP, Zhang XM. Heat shock protein 70/ MAGE-3 fusion protein vaccine can enhance cellular and humoral immune responses to MAGE-3 in vivo. Cancer Immunol Immunother 2005; 54:907-14; PMID:15756604; http://dx. doi. org/10. 1007/s00262- 004-0660-3
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 907-914
    • Ma, J.1    Sui, Y.F.2    Ye, J.3    Huang, Y.Y.4    Li, Z.S.5    Chen, G.S.6    Qu, P.7    Song, H.P.8    Zhang, X.M.9
  • 103
    • 0028316911 scopus 로고
    • Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor
    • PMID:8170938
    • Kawakami Y, Eliyahu S, Delgado CH, Robbins PF, Rivoltini L, Topalian SL, Miki T, Rosenberg SA. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc Natl Acad Sci U S A 1994; 91:3515-9; PMID:8170938; http://dx. doi. org/ 10. 1073/pnas. 91. 9. 3515
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3515-3519
    • Kawakami, Y.1    Eliyahu, S.2    Delgado, C.H.3    Robbins, P.F.4    Rivoltini, L.5    Topalian, S.L.6    Miki, T.7    Rosenberg, S.A.8
  • 105
    • 0027165558 scopus 로고
    • The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas
    • PMID:8340755
    • Brichard V, Van Pel A, Wölfel T, Wölfel C, De Plaen E, Lethé B, Coulie P, Boon T. The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med 1993; 178:489-95; PMID:8340755; http://dx. doi. org/10. 1084/jem. 178. 2. 489
    • (1993) J Exp Med , vol.178 , pp. 489-495
    • Brichard, V.1    Van Pel, A.2    Wölfel, T.3    Wölfel, C.4    De Plaen, E.5    Lethé, B.6    Coulie, P.7    Boon, T.8
  • 106
    • 0036194504 scopus 로고    scopus 로고
    • Induction of a systemic immune response by a polyvalent melanoma-associated antigen DNA vaccine for prevention and treatment of malignant melanoma
    • PMID:11863419
    • Tanaka M, Kaneda Y, Fujii S, Yamano T, Hashimoto K, Huang SK, Hoon DS. Induction of a systemic immune response by a polyvalent melanoma-associated antigen DNA vaccine for prevention and treatment of malignant melanoma. Mol Ther 2002; 5:291-9; PMID:11863419; http://dx. doi. org/ 10. 1006/mthe. 2002. 0537
    • (2002) Mol Ther , vol.5 , pp. 291-299
    • Tanaka, M.1    Kaneda, Y.2    Fujii, S.3    Yamano, T.4    Hashimoto, K.5    Huang, S.K.6    Hoon, D.S.7
  • 107
    • 0034090894 scopus 로고    scopus 로고
    • Genetic immunization of mice with human tyrosinase- related protein 2: Implications for the immunotherapy of melanoma
    • PMID:10728600
    • Steitz J, Brück J, Steinbrink K, Enk A, Knop J, Tüting T. Genetic immunization of mice with human tyrosinase- related protein 2: implications for the immunotherapy of melanoma. Int J Cancer 2000; 86:89-94; PMID:10728600; http://dx. doi. org/10. 1002/(SICI) 1097-0215(20000401)86:1%3c89::AID-IJC14%3e3. 0. CO;2-I
    • (2000) Int J Cancer , vol.86 , pp. 89-94
    • Steitz, J.1    Brück, J.2    Steinbrink, K.3    Enk, A.4    Knop, J.5    Tüting, T.6
  • 109
    • 33846879410 scopus 로고    scopus 로고
    • A phase I study of immunization using particle-mediated epidermal delivery of genes for gp100 and GM-CSF into uninvolved skin of melanoma patients
    • PMID:17255276
    • Cassaday R, Sondel PM, King DM, Macklin MD, Gan J, Warner TF, Zuleger CL, Bridges AJ, Schalch HG, Kim KM, et al. A phase I study of immunization using particle-mediated epidermal delivery of genes for gp100 and GM-CSF into uninvolved skin of melanoma patients. Clin Cancer Res 2007; 13:540-9; PMID:17255276; http://dx. doi. org/10. 1158/1078- 0432. CCR-06-2039
    • (2007) Clin Cancer Res , vol.13 , pp. 540-549
    • Cassaday, R.1    Sondel, P.M.2    King, D.M.3    McKlin, M.D.4    Gan, J.5    Warner, T.F.6    Zuleger, C.L.7    Bridges, A.J.8    Schalch, H.G.9    Kim, K.M.10
  • 111
    • 0015168172 scopus 로고
    • Autoimmune-like antibodies to the ligand-binding sites of myeloma proteins
    • PMID:4108872
    • Sirisinha S, Eisen HN. Autoimmune-like antibodies to the ligand-binding sites of myeloma proteins. Proc Natl Acad Sci U S A 1971; 68:3130-5; PMID:4108872; http://dx. doi. org/10. 1073/ pnas. 68. 12. 3130
    • (1971) Proc Natl Acad Sci U S A , vol.68 , pp. 3130-3135
    • Sirisinha, S.1    Eisen, H.N.2
  • 112
    • 0015353478 scopus 로고
    • Myeloma proteins as tumor-specific transplantation antigens
    • PMID:4113870
    • Lynch RG, Graff RJ, Sirisinha S, Simms ES, Eisen HN. Myeloma proteins as tumor-specific transplantation antigens. Proc Natl Acad Sci U S A 1972; 69:1540-4; PMID:4113870; http://dx. doi. org/ 10. 1073/pnas. 69. 6. 1540
    • (1972) Proc Natl Acad Sci U S A , vol.69 , pp. 1540-1544
    • Lynch, R.G.1    Graff, R.J.2    Sirisinha, S.3    Simms, E.S.4    Eisen, H.N.5
  • 113
    • 77950539903 scopus 로고    scopus 로고
    • Vaccine site inflammation potentiates idiotype DNA vaccine-induced therapeutic T cell-, and not B cell-, dependent antilymphoma immunity
    • PMID:19749091
    • Qin H, Cha SC, Neelapu SS, Lou Y, Wei J, Liu YJ, Kwak LW. Vaccine site inflammation potentiates idiotype DNA vaccine-induced therapeutic T cell-, and not B cell-, dependent antilymphoma immunity. Blood 2009; 114:4142-9; PMID:19749091; http:// dx. doi. org/10. 1182/blood-2009-05-219683
    • (2009) Blood , vol.114 , pp. 4142-4149
    • Qin, H.1    Cha, S.C.2    Neelapu, S.S.3    Lou, Y.4    Wei, J.5    Liu, Y.J.6    Kwak, L.W.7
  • 114
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • PMID:9039259
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88:323-31; PMID:9039259; http://dx. doi. org/10. 1016/S0092-8674(00)81871-1
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 115
    • 0033579412 scopus 로고    scopus 로고
    • Regulation of the p53 tumor suppressor protein
    • PMID:10593882
    • Oren M. Regulation of the p53 tumor suppressor protein. J Biol Chem 1999; 274:36031-4; PMID:10593882; http://dx. doi. org/10. 1074/jbc. 274. 51. 36031
    • (1999) J Biol Chem , vol.274 , pp. 36031-36034
    • Oren, M.1
  • 116
    • 0029919634 scopus 로고    scopus 로고
    • Somatic point mutations in the p53 gene of human tumors and cell lines: Updated compilation
    • PMID:8594564
    • Hollstein M, Shomer B, Greenblatt M, Soussi T, Hovig E, Montesano R, Harris CC. Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation. Nucleic Acids Res 1996; 24:141-6; PMID:8594564; http://dx. doi. org/ 10. 1093/nar/24. 1. 141
    • (1996) Nucleic Acids Res , vol.24 , pp. 141-146
    • Hollstein, M.1    Shomer, B.2    Greenblatt, M.3    Soussi, T.4    Hovig, E.5    Montesano, R.6    Harris, C.C.7
  • 117
    • 84874091596 scopus 로고    scopus 로고
    • Xenogeneic human p53 DNA vaccination by electroporation breaks immune tolerance to control murine tumors expressing mouse p53
    • PMID:23457640
    • Soong RS, Trieu J, Lee SY, He L, Tsai YC, Wu TC, Hung CF. Xenogeneic human p53 DNA vaccination by electroporation breaks immune tolerance to control murine tumors expressing mouse p53. PLoS One 2013; 8:e56912; PMID:23457640; http://dx. doi. org/ 10. 1371/journal. pone. 0056912
    • (2013) PLoS One , vol.8
    • Soong, R.S.1    Trieu, J.2    Lee, S.Y.3    He, L.4    Tsai, Y.C.5    Wu, T.C.6    Hung, C.F.7
  • 118
    • 84914673021 scopus 로고    scopus 로고
    • DNA vaccines targeting human papillomavirus- associated diseases: Progresses in animal and clinical studies
    • PMID:23858401
    • Han KT, Sin JI. DNA vaccines targeting human papillomavirus- associated diseases: progresses in animal and clinical studies. Clin Exp Vaccine Res 2013; 2:106-14; PMID:23858401; http://dx. doi. org/ 10. 7774/cevr. 2013. 2. 2. 106
    • (2013) Clin Exp Vaccine Res , vol.2 , pp. 106-114
    • Han, K.T.1    Sin, J.I.2
  • 119
    • 0024535228 scopus 로고
    • The human papillomavirus-16 E7 oncoprotein is able to bind the retinoblastoma gene product
    • PMID:2537532
    • Dyson N, Howley PM, Munger K, Harlow E. The human papillomavirus-16 E7 oncoprotein is able to bind the retinoblastoma gene product. Science 1989; 243:934-7; PMID:2537532; http://dx. doi. org/ 10. 1126/science. 2537532
    • (1989) Science , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 120
    • 0025271203 scopus 로고
    • Association of human papillomavirus type 16 and 18 E6 protein with p53
    • PMID:2157286
    • Werness BA, Levine AJ, Howley PM. Association of human papillomavirus type 16 and 18 E6 protein with p53. Science 1990; 248:76-9; PMID:2157286; http://dx. doi. org/10. 1126/science. 2157286
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 121
    • 0034788572 scopus 로고    scopus 로고
    • Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen
    • PMID:11544272
    • Cheng WF, Hung CF, Chai CY, Hsu KF, He L, Ling M, Wu TC. Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen. J Clin Invest 2001; 108:669-78; PMID:11544272; http://dx. doi. org/ 10. 1172/JCI200112346
    • (2001) J Clin Invest , vol.108 , pp. 669-678
    • Cheng, W.F.1    Hung, C.F.2    Chai, C.Y.3    Hsu, K.F.4    He, L.5    Ling, M.6    Wu, T.C.7
  • 122
    • 79956122546 scopus 로고    scopus 로고
    • Antitumor therapeutic and antimetastatic activity of electroporation-delivered human papillomavirus 16 E7 DNA vaccines: A possible mechanism for enhanced tumor control
    • Lee IH, Park JB, Cheong M, Choi YS, Park D, Sin JI. Antitumor therapeutic and antimetastatic activity of electroporation-delivered human papillomavirus 16 E7 DNA vaccines: a possible mechanism for enhanced tumor control. DNA Cell Biol 2011; 30:975-85; http://dx. doi. org/10. 1089/dna. 2011. 1266
    • (2011) DNA Cell Biol , vol.30 , pp. 975-985
    • Lee, I.H.1    Park, J.B.2    Cheong, M.3    Choi, Y.S.4    Park, D.5    Sin, J.I.6
  • 123
    • 27644457376 scopus 로고    scopus 로고
    • TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
    • PMID:16286245
    • Thomas DA, Massagué J. TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 2005; 8:369-80; PMID:16286245; http://dx. doi. org/10. 1016/j. ccr. 2005. 10. 012
    • (2005) Cancer Cell , vol.8 , pp. 369-380
    • Thomas, D.A.1    Massagué, J.2
  • 124
    • 68849129604 scopus 로고    scopus 로고
    • Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer
    • PMID:19604349
    • Mansfield AS, Heikkila PS, Vaara AT, von Smitten KA, Vakkila JM, Leidenius MH. Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer. BMC Cancer 2009; 9:231; PMID:19604349; http://dx. doi. org/10. 1186/ 1471-2407-9-231
    • (2009) BMC Cancer , vol.9 , pp. 231
    • Mansfield, A.S.1    Heikkila, P.S.2    Vaara, A.T.3    von Smitten, K.A.4    Vakkila, J.M.5    Leidenius, M.H.6
  • 125
    • 0037136328 scopus 로고    scopus 로고
    • Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2, 3- dioxygenase
    • PMID:12186838
    • Frumento G, Rotondo R, Tonetti M, Damonte G, Benatti U, Ferrara GB. Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2, 3- dioxygenase. J Exp Med 2002; 196:459-68; PMID:12186838; http://dx. doi. org/10. 1084/ jem. 20020121
    • (2002) J Exp Med , vol.196 , pp. 459-468
    • Frumento, G.1    Rotondo, R.2    Tonetti, M.3    Damonte, G.4    Benatti, U.5    Ferrara, G.B.6
  • 126
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • PMID:12091876
    • Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, Roche PC, Lu J, Zhu G, Tamada K, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8:793-800; PMID:12091876; http:// dx. doi. org/10. 1038/nm0902-1039c
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3    Tamura, H.4    Hirano, F.5    Flies, D.B.6    Roche, P.C.7    Lu, J.8    Zhu, G.9    Tamada, K.10
  • 128
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • PMID:12218188
    • Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A 2002; 99:12293-7; PMID:12218188; http://dx. doi. org/10. 1073/pnas. 192461099
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 130
    • 0038620323 scopus 로고    scopus 로고
    • Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function
    • PMID:12794118
    • Thiery J, Dorothée G, Haddada H, Echchakir H, Richon C, Stancou R, Vergnon I, Benard J, Mami- Chouaib F, Chouaib S. Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function. J Immunol 2003; 170:5919-26; PMID:12794118; http://dx. doi. org/ 10. 4049/jimmunol. 170. 12. 5919
    • (2003) J Immunol , vol.170 , pp. 5919-5926
    • Thiery, J.1    Dorothée, G.2    Haddada, H.3    Echchakir, H.4    Richon, C.5    Stancou, R.6    Vergnon, I.7    Benard, J.8    Mami-Chouaib, F.9    Chouaib, S.10
  • 131
    • 0035949570 scopus 로고    scopus 로고
    • Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors
    • PMID:11562487
    • Medema JP, de Jong J, Peltenburg LT, Verdegaal EM, Gorter A, Bres SA, Franken KL, Hahne M, Albar JP, Melief CJ, et al. Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors. Proc Natl Acad Sci USA 2001; 98:11515-20; PMID:11562487; http://dx. doi. org/10. 1073/pnas. 201398198
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11515-11520
    • Medema, J.P.1    de Jong, J.2    Peltenburg, L.T.3    Verdegaal, E.M.4    Gorter, A.5    Bres, S.A.6    Franken, K.L.7    Hahne, M.8    Albar, J.P.9    Melief, C.J.10
  • 132
    • 0033523670 scopus 로고    scopus 로고
    • Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein
    • PMID:10510093
    • Medema JP, de Jong J, van Hall T, Melief CJ, Offringa R. Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein. J Exp Med 1999; 190:1033-8; PMID:10510093; http://dx. doi. org/10. 1084/jem. 190. 7. 1033
    • (1999) J Exp Med , vol.190 , pp. 1033-1038
    • Medema, J.P.1    de Jong, J.2    van Hall, T.3    Melief, C.J.4    Offringa, R.5
  • 133
    • 85047690959 scopus 로고    scopus 로고
    • Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes
    • PMID:12750398
    • Bai XF, Liu J, Li O, Zheng P, Liu Y. Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes. J Clin Invest 2003; 111:1487-96; PMID:12750398; http://dx. doi. org/ 10. 1172/JCI17656
    • (2003) J Clin Invest , vol.111 , pp. 1487-1496
    • Bai, X.F.1    Liu, J.2    Li, O.3    Zheng, P.4    Liu, Y.5
  • 134
    • 0035135082 scopus 로고    scopus 로고
    • Persistence of immunogenic pulmonary metastases in the presence of protective anti-melanoma immunity
    • PMID:11196164
    • Douawho CK, Pride MW, Kripke ML. Persistence of immunogenic pulmonary metastases in the presence of protective anti-melanoma immunity. Cancer Res 2001; 61:215-21; PMID:11196164
    • (2001) Cancer Res , vol.61 , pp. 215-221
    • Douawho, C.K.1    Pride, M.W.2    Kripke, M.L.3
  • 135
    • 84944458932 scopus 로고    scopus 로고
    • MC32 tumor cells acquire Ag-specific CTL resistance through the loss of CEA in a colon cancer model
    • In press
    • Lee SY, Sin JI. MC32 tumor cells acquire Ag-specific CTL resistance through the loss of CEA in a colon cancer model. Hum Vaccin Immunother 2015; In press
    • (2015) Hum Vaccin Immunother
    • Lee, S.Y.1    Sin, J.I.2
  • 136
    • 84918529757 scopus 로고    scopus 로고
    • MHC class I loss is a frequent mechanism of immune escape in papillary thyroid cancer that is reversed by interferon and selumetinib treatment in vitro
    • pii: clincanres. 0879. 2014; PMID:25294906
    • Angell TE, Lechner MG, Jang JK, LoPresti JS, Epstein AL. MHC class I loss is a frequent mechanism of immune escape in papillary thyroid cancer that is reversed by interferon and selumetinib treatment in vitro. Clin Cancer Res 2014; 20(23):6034-44; pii: clincanres. 0879. 2014; PMID:25294906; http://dx. doi. org/10. 1158/1078-0432. CCR-14-0879
    • (2014) Clin Cancer Res , vol.20 , Issue.23 , pp. 6034-6044
    • Angell, T.E.1    Lechner, M.G.2    Jang, J.K.3    LoPresti, J.S.4    Epstein, A.L.5
  • 137
    • 79951846234 scopus 로고    scopus 로고
    • Molecular mechanism of MART-1+/ A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction
    • PMID:21159666
    • Jazirehi AR, Baritaki S, Koya RC, Bonavida B, Economou JS. Molecular mechanism of MART-1+/ A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction. Cancer Res 2011; 71:1406-17; PMID:21159666; http://dx. doi. org/10. 1158/0008- 5472. CAN-10-1296
    • (2011) Cancer Res , vol.71 , pp. 1406-1417
    • Jazirehi, A.R.1    Baritaki, S.2    Koya, R.C.3    Bonavida, B.4    Economou, J.S.5
  • 138
    • 84857692141 scopus 로고    scopus 로고
    • Differential macrophage programming in the tumor microenvironment
    • PMID:22277903
    • Ruffell B, Affara NI, Coussens LM. Differential macrophage programming in the tumor microenvironment. Trends Immunol 2012; 33:119-26; PMID:22277903; http://dx. doi. org/10. 1016/j. it. 2011. 12. 001
    • (2012) Trends Immunol , vol.33 , pp. 119-126
    • Ruffell, B.1    Affara, N.I.2    Coussens, L.M.3
  • 139
    • 84913556128 scopus 로고    scopus 로고
    • Targeting regulatory T cells to improve vaccine immunogenecity in early life
    • PMID:25309517
    • Ndure J, Flanagan KL. Targeting regulatory T cells to improve vaccine immunogenecity in early life. Front Microbiol 2014; 5:477; PMID:25309517; http://dx. doi. org/10. 3389/fmicb. 2014. 00477
    • (2014) Front Microbiol , vol.5 , pp. 477
    • Ndure, J.1    Flanagan, K.L.2
  • 140
    • 79959856425 scopus 로고    scopus 로고
    • Antigen specificity of immune suppression by myeloid-derived suppressor cells
    • PMID:21486906
    • Solito S, Bronte V, Mandruzzato S. Antigen specificity of immune suppression by myeloid-derived suppressor cells. J Leukoc Biol 2011; 90:31-6; PMID:21486906; http://dx. doi. org/10. 1189/ jlb. 0111021
    • (2011) J Leukoc Biol , vol.90 , pp. 31-36
    • Solito, S.1    Bronte, V.2    Mandruzzato, S.3
  • 141
    • 33846302030 scopus 로고    scopus 로고
    • Therapeutic synergy of human papillomavirus E7 subunit vaccines plus cisplatin in an animal tumor model: Causal involvement of increased sensitivity of cisplatin- treated tumors to CTL-mediated killing in therapeutic synergy
    • PMID:17200373
    • Bae SH, Park YJ, Park JB, Choi YS, Kim MS, Sin JI. Therapeutic synergy of human papillomavirus E7 subunit vaccines plus cisplatin in an animal tumor model: causal involvement of increased sensitivity of cisplatin- treated tumors to CTL-mediated killing in therapeutic synergy. Clin Cancer Res 2007; 13:341-9; PMID:17200373; http://dx. doi. org/10. 1158/1078- 0432. CCR-06-1838
    • (2007) Clin Cancer Res , vol.13 , pp. 341-349
    • Bae, S.H.1    Park, Y.J.2    Park, J.B.3    Choi, Y.S.4    Kim, M.S.5    Sin, J.I.6
  • 142
    • 34547133955 scopus 로고    scopus 로고
    • Increased sensitivity of radiated murine cervical cancer tumors to E7 subunit vaccine-driven CTL-mediated killing induces synergistic antitumor activity
    • PMID:17505485
    • Ye GW, Park JB, Park YJ, Choi YS, Sin JI. Increased sensitivity of radiated murine cervical cancer tumors to E7 subunit vaccine-driven CTL-mediated killing induces synergistic antitumor activity. Mol Ther 2007; 15:1564-70; PMID:17505485; http://dx. doi. org/10. 1038/sj. mt. 6300149
    • (2007) Mol Ther , vol.15 , pp. 1564-1570
    • Ye, G.W.1    Park, J.B.2    Park, Y.J.3    Choi, Y.S.4    Sin, J.I.5
  • 143
    • 67349231629 scopus 로고    scopus 로고
    • Adoptive transfer of human papillomavirus E7-specific CTL enhances tumor chemoresponse through the perforin/granzyme-mediated pathway
    • PMID:19277009
    • Sin JI, Kim JM, Bae SH, Lee IH, Park JS, Ryoo HM. Adoptive transfer of human papillomavirus E7-specific CTL enhances tumor chemoresponse through the perforin/granzyme-mediated pathway. Mol Ther 2009; 17:906-13; PMID:19277009; http://dx. doi. org/10. 1038/mt. 2009. 32
    • (2009) Mol Ther , vol.17 , pp. 906-913
    • Sin, J.I.1    Kim, J.M.2    Bae, S.H.3    Lee, I.H.4    Park, J.S.5    Ryoo, H.M.6
  • 144
    • 77953036244 scopus 로고    scopus 로고
    • Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: A pilot clinical trial
    • PMID:20529245
    • Norell H, Poschke I, Charo J, Wei WZ, Erskine C, Piechocki MP, Knutson KL, Bergh J, Lidbrink E, Kiessling R. Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial. J Transl Med 2010; 8:53; PMID:20529245; http://dx. doi. org/10. 1186/1479- 5876-8-53
    • (2010) J Transl Med , vol.8 , pp. 53
    • Norell, H.1    Poschke, I.2    Charo, J.3    Wei, W.Z.4    Erskine, C.5    Piechocki, M.P.6    Knutson, K.L.7    Bergh, J.8    Lidbrink, E.9    Kiessling, R.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.