IL-12 plasmid-enhanced DNA vaccination against carcinoembryonic antigen (CEA) studied in immune-gene knockout mice

Gene Therapy

Volumn 7, Issue 18, 2000, Pages 1527-1535

  Song, K ^a   Chang, Y ^a   Prud Homme, G J ^a   Roffler, S R ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Carcinoembryonic antigen; DNA vaccination; Gene knockout mice; Interleukin 12; Lewis lung carcinoma

Indexed keywords

CARCINOEMBRYONIC ANTIBODY; CARCINOEMBRYONIC ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; DNA VACCINE; FAS LIGAND; GAMMA INTERFERON; INTERLEUKIN 12; PERFORIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DELAYED HYPERSENSITIVITY; IMMUNE RESPONSE; INTERFERON PRODUCTION; KNOCKOUT GENE; KNOCKOUT MOUSE; LEWIS CARCINOMA; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TUMOR RESISTANCE;

ANIMAL; ANTIBODY FORMATION; ANTIGENS, CD3; ANTIGENS, CD4; ANTIGENS, CD8; CARCINOEMBRYONIC ANTIGEN; COMPARATIVE STUDY; FEMALE; GENE THERAPY; HUMAN; INJECTIONS, INTRAMUSCULAR; INTERFERON TYPE II; INTERLEUKIN-12; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; PLASMIDS; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS; TIME FACTORS; TUMOR CELLS, CULTURED; VACCINES, DNA;

EID: 0033780172     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301274     Document Type: Article

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