IL-12 plasmid delivery by in Vivo electroporation for the successful treatment of established subcutaneous B16.F10 melanoma

Molecular Therapy

Volumn 5, Issue 6, 2002, Pages 668-675

  Lucas, M Lee ^a   Heller, Loree ^a   Coppola, Domenico ^b   Heller, Richard ^a,c  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

B16.F10; Electroporation; Gene therapy; IL 12; Melanoma; Plasmid DNA

Indexed keywords

ANTINEOPLASTIC AGENT; GAMMA INTERFERON; INTERLEUKIN 12; PLASMID DNA; RECOMBINANT PROTEIN; ANGIOGENESIS INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER IMMUNOTHERAPY; CANCER LOCALIZATION; CLINICAL PROTOCOL; CONTROLLED STUDY; ELECTRODE; ELECTROPORATION; GENE DELIVERY SYSTEM; GENE THERAPY; IN VIVO STUDY; LYMPHOCYTE MIGRATION; MELANOMA; MOUSE; NONHUMAN; NUDE MOUSE; SUBCUTANEOUS TISSUE; T LYMPHOCYTE; TREATMENT OUTCOME; TUMOR REGRESSION; TUMOR VASCULARIZATION; ANIMAL; BLOOD; C57BL MOUSE; CELL CULTURE; EXPERIMENTAL MELANOMA; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; PLASMID; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALIA; MURINAE; MUS; MUS MUSCULUS;

ANGIOGENESIS INHIBITORS; ANIMALS; ELECTROPORATION; GENE THERAPY; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; INTERLEUKIN-12; LYMPHOCYTES, TUMOR-INFILTRATING; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, NUDE; PLASMIDS; TUMOR CELLS, CULTURED;

EID: 0036594813     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2002.0601     Document Type: Article

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