메뉴 건너뛰기




Volumn 32, Issue , 2015, Pages 127-133

The SWI/SNF chromatin remodelling complex: Its role in maintaining genome stability and preventing tumourigenesis

Author keywords

BAF180; BRG1; Chromatin remodelling complex; Cohesion; DNA damage induced transcriptional repression; Genome instability; PBAF; SWI SNF; Tumourigenesis

Indexed keywords

BARRIER TO AUTOINTEGRATION FACTOR; BRG1 PROTEIN; PROTEIN SWI; TRANSCRIPTION FACTOR SNF; BANF1 PROTEIN, HUMAN; DNA BINDING PROTEIN; DNA HELICASE; NONHISTONE PROTEIN; NUCLEAR PROTEIN; SMARCA4 PROTEIN, HUMAN; SWI-SNF-B CHROMATIN-REMODELING COMPLEX; TRANSCRIPTION FACTOR;

EID: 84938209208     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2015.04.023     Document Type: Article
Times cited : (67)

References (62)
  • 1
    • 84883732664 scopus 로고    scopus 로고
    • Nucleosome sliding mechanisms: new twists in a looped history
    • Mueller-Planitz F., Klinker H., Becker P.B. Nucleosome sliding mechanisms: new twists in a looped history. Nat. Struct. Mol. Biol. 2013, 20:1026-1032. 10.1038/nsmb.2648.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 1026-1032
    • Mueller-Planitz, F.1    Klinker, H.2    Becker, P.B.3
  • 2
    • 84919455929 scopus 로고    scopus 로고
    • Roles of chromatin remodellers in DNA double strand break repair
    • Jeggo P.A., Downs J.A. Roles of chromatin remodellers in DNA double strand break repair. Exp. Cell Res. 2014, 329:69-77. 10.1016/j.yexcr.2014.09.023.
    • (2014) Exp. Cell Res. , vol.329 , pp. 69-77
    • Jeggo, P.A.1    Downs, J.A.2
  • 4
    • 84919485360 scopus 로고    scopus 로고
    • Chromatin modifications and DNA repair: beyond double-strand breaks
    • House N.C., Koch M.R., Freudenreich C.H. Chromatin modifications and DNA repair: beyond double-strand breaks. Front. Genet. 2014, 5(296). 10.3389/fgene.2014.00296.
    • (2014) Front. Genet. , vol.5 , Issue.296
    • House, N.C.1    Koch, M.R.2    Freudenreich, C.H.3
  • 5
    • 84878745222 scopus 로고    scopus 로고
    • Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
    • Kadoch C., et al. Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. Nat. Genet. 2013, 45:592-601. 10.1038/ng.2628.
    • (2013) Nat. Genet. , vol.45 , pp. 592-601
    • Kadoch, C.1
  • 6
    • 84926157747 scopus 로고    scopus 로고
    • Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes
    • Leiserson M.D., et al. Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes. Nat. Genet. 2014, 10.1038/ng.3168.
    • (2014) Nat. Genet.
    • Leiserson, M.D.1
  • 7
    • 84872810488 scopus 로고    scopus 로고
    • The spectrum of SWI/SNF mutations, ubiquitous in human cancers
    • Shain A.H., Pollack J.R. The spectrum of SWI/SNF mutations, ubiquitous in human cancers. PLoS ONE 2013, 8:e5119. 10.1371/journal.pone.0055119.
    • (2013) PLoS ONE , vol.8 , pp. e5119
    • Shain, A.H.1    Pollack, J.R.2
  • 9
    • 84901635855 scopus 로고    scopus 로고
    • The SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseases
    • Romero O.A., Sanchez-Cespedes M. The SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseases. Oncogene 2014, 33:2681-2689. 10.1038/onc.2013.227.
    • (2014) Oncogene , vol.33 , pp. 2681-2689
    • Romero, O.A.1    Sanchez-Cespedes, M.2
  • 10
    • 79959653996 scopus 로고    scopus 로고
    • SWI/SNF nucleosome remodellers and cancer
    • Wilson B.G., Roberts C. SWI/SNF nucleosome remodellers and cancer. Nat. Rev. Cancer 2011, 11:481-492. 10.1038/nrc3068.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 481-492
    • Wilson, B.G.1    Roberts, C.2
  • 11
    • 84897990643 scopus 로고    scopus 로고
    • Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
    • Aymard F., et al. Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks. Nat. Struct. Mol. Biol. 2014, 21:366-374. 10.1038/nsmb.2796.
    • (2014) Nat. Struct. Mol. Biol. , vol.21 , pp. 366-374
    • Aymard, F.1
  • 12
    • 84903451450 scopus 로고    scopus 로고
    • SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability
    • Pfister S.X., et al. SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability. Cell Rep. 2014, 7:2006-2018. 10.1016/j.celrep.2014.05.026.
    • (2014) Cell Rep. , vol.7 , pp. 2006-2018
    • Pfister, S.X.1
  • 13
    • 84862995618 scopus 로고    scopus 로고
    • The RSC and INO80 chromatin-remodeling complexes in DNA double-strand break repair
    • Chambers A.L., Downs J.A. The RSC and INO80 chromatin-remodeling complexes in DNA double-strand break repair. Prog. Mol. Biol. Transl. Sci. 2012, 110:229-261. 10.1016/B978-0-12-387665-2.00009-2.
    • (2012) Prog. Mol. Biol. Transl. Sci. , vol.110 , pp. 229-261
    • Chambers, A.L.1    Downs, J.A.2
  • 14
    • 67650034511 scopus 로고    scopus 로고
    • Et al. BRIT1/MCPH1 links chromatin remodelling to DNA damage response
    • Peng G. et al. BRIT1/MCPH1 links chromatin remodelling to DNA damage response. Nat. Cell Biol. 2009, 11:865-872. 10.1038/ncb1895.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 865-872
    • Peng, G.1
  • 15
    • 84921368168 scopus 로고    scopus 로고
    • BRG1 promotes DNA double-strand break repair by facilitating the replacement of RPA with RAD 51
    • Qi W., et al. BRG1 promotes DNA double-strand break repair by facilitating the replacement of RPA with RAD 51. J. Cell Sci. 2014, 10.1242/jcs.159103.
    • (2014) J. Cell Sci.
    • Qi, W.1
  • 16
    • 84900007190 scopus 로고    scopus 로고
    • SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability
    • CAN-13-3608
    • Watanabe R., et al. SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability. Cancer Res. 2014, 74:2465-2475. CAN-13-3608. 10.1158/0008-5472.
    • (2014) Cancer Res. , vol.74 , pp. 2465-2475
    • Watanabe, R.1
  • 17
    • 77951498720 scopus 로고    scopus 로고
    • A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair
    • Lee H.S., Park J.H., Kim S.J., Kwon S.J., Kwon J. A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair. EMBO J. 2010, 29:1434-1445. 10.1038/emboj.2010.27.
    • (2010) EMBO J. , vol.29 , pp. 1434-1445
    • Lee, H.S.1    Park, J.H.2    Kim, S.J.3    Kwon, S.J.4    Kwon, J.5
  • 18
    • 79955613209 scopus 로고    scopus 로고
    • Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors
    • Ogiwara H., et al. Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene 2011, 30:2135-2146. 10.1038/onc.2010.592.
    • (2011) Oncogene , vol.30 , pp. 2135-2146
    • Ogiwara, H.1
  • 19
    • 84898006643 scopus 로고    scopus 로고
    • Possible involvement of LKB1-AMPK signaling in non-homologous end joining
    • Ui A., et al. Possible involvement of LKB1-AMPK signaling in non-homologous end joining. Oncogene 2014, 33:1640-1648. 10.1038/onc.2013.125.
    • (2014) Oncogene , vol.33 , pp. 1640-1648
    • Ui, A.1
  • 20
    • 84881612908 scopus 로고    scopus 로고
    • Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription
    • Shema-Yaacoby E., et al. Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Rep. 2013, 4:601-608. 10.1016/j.celrep.2013.07.014.
    • (2013) Cell Rep. , vol.4 , pp. 601-608
    • Shema-Yaacoby, E.1
  • 22
    • 34249941966 scopus 로고    scopus 로고
    • Translesion synthesis: Y-family polymerases and the polymerase switch
    • Lehmann A.R., et al. Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair (Amst.) 2007, 6:891-899.
    • (2007) DNA Repair (Amst.) . , vol.6 , pp. 891-899
    • Lehmann, A.R.1
  • 23
    • 84901419546 scopus 로고    scopus 로고
    • Cohesin in cancer: chromosome segregation and beyond
    • Losada A. Cohesin in cancer: chromosome segregation and beyond. Nat. Rev. Cancer 2014, 14:389-393. 10.1038/nrc3743.
    • (2014) Nat. Rev. Cancer , vol.14 , pp. 389-393
    • Losada, A.1
  • 24
    • 84897050302 scopus 로고    scopus 로고
    • BAF180 Promotes Cohesion and Prevents Genome Instability and Aneuploidy
    • Brownlee P.M., Chambers A.L., Cloney R., Bianchi A., Downs, JA BAF180 Promotes Cohesion and Prevents Genome Instability and Aneuploidy. Cell Rep. 2014, 6:973-981. 10.1016/j.celrep.2014.02.012.
    • (2014) Cell Rep. , vol.6 , pp. 973-981
    • Brownlee, P.M.1    Chambers, A.L.2    Cloney, R.3    Bianchi, A.4    Downs, J.A.5
  • 25
    • 84885021313 scopus 로고    scopus 로고
    • Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms
    • Kon A., et al. Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms. Nat. Genet. 2013, 45:1232-1237. 10.1038/ng.2731.
    • (2013) Nat. Genet. , vol.45 , pp. 1232-1237
    • Kon, A.1
  • 26
    • 70449731229 scopus 로고    scopus 로고
    • Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells
    • Canudas S., Smith S. Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells. J. Cell Biol. 2009, 187:165-173. 10.1083/jcb.200903096.
    • (2009) J. Cell Biol. , vol.187 , pp. 165-173
    • Canudas, S.1    Smith, S.2
  • 27
    • 84855356369 scopus 로고    scopus 로고
    • Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin
    • Whelan G., et al. Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin. EMBO J. 2012, 31:71-82. 10.1038/emboj.2011.381.
    • (2012) EMBO J. , vol.31 , pp. 71-82
    • Whelan, G.1
  • 28
    • 84887819535 scopus 로고    scopus 로고
    • Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres
    • Carretero M., Ruiz-Torres M., Rodriguez-Corsino M., Barthelemy I., Losada, A Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres. EMBO J. 2013, 32:2938-2949. 10.1038/emboj.2013.230.
    • (2013) EMBO J. , vol.32 , pp. 2938-2949
    • Carretero, M.1    Ruiz-Torres, M.2    Rodriguez-Corsino, M.3    Barthelemy, I.4    Losada, A.5
  • 29
    • 80051871652 scopus 로고    scopus 로고
    • Aneuploidy drives genomic instability in yeast
    • Sheltzer J.M., et al. Aneuploidy drives genomic instability in yeast. Science 2011, 333:1026-1030. 10.1126/science.1206412.
    • (2011) Science , vol.333 , pp. 1026-1030
    • Sheltzer, J.M.1
  • 30
    • 84888340419 scopus 로고    scopus 로고
    • Frequent truncating mutations of STAG2 in bladder cancer
    • Solomon D.A., et al. Frequent truncating mutations of STAG2 in bladder cancer. Nat. Genet. 2013, 45:1428-1430. 10.1038/ng.2800.
    • (2013) Nat. Genet. , vol.45 , pp. 1428-1430
    • Solomon, D.A.1
  • 31
    • 84888380730 scopus 로고    scopus 로고
    • Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation
    • Guo G., et al. Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. Nat. Genet. 2013, 45:1459-1463. 10.1038/ng.2798.
    • (2013) Nat. Genet. , vol.45 , pp. 1459-1463
    • Guo, G.1
  • 32
    • 84888354078 scopus 로고    scopus 로고
    • Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy
    • Balbas-Martinez C., et al. Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy. Nat. Genet. 2013, 45:1464-1469. 10.1038/ng.2799.
    • (2013) Nat. Genet. , vol.45 , pp. 1464-1469
    • Balbas-Martinez, C.1
  • 33
    • 84884418423 scopus 로고    scopus 로고
    • Frameshift mutations of chromosome cohesion-related genes SGOL1 and PDS5B in gastric and colorectal cancers with high microsatellite instability
    • Kim M.S., An C.H., Yoo N.J., Lee S.H. Frameshift mutations of chromosome cohesion-related genes SGOL1 and PDS5B in gastric and colorectal cancers with high microsatellite instability. Hum. Pathol. 2013, 44:2234-2240. 10.1016/j.humpath.2013.04.017.
    • (2013) Hum. Pathol. , vol.44 , pp. 2234-2240
    • Kim, M.S.1    An, C.H.2    Yoo, N.J.3    Lee, S.H.4
  • 34
    • 84896399546 scopus 로고    scopus 로고
    • Suppression of genome instability in pRB-deficient cells by enhancement of chromosome cohesion
    • Manning A.L., et al. Suppression of genome instability in pRB-deficient cells by enhancement of chromosome cohesion. Mol. Cell 2014, 53:993-1004. 10.1016/j.molcel.2014.01.032\.
    • (2014) Mol. Cell , vol.53 , pp. 993-1004
    • Manning, A.L.1
  • 35
    • 84919798077 scopus 로고    scopus 로고
    • Loss of BRCA1 impairs centromeric cohesion and triggers chromosomal instability
    • Di Paolo A., Racca C., Calsou P., Larminat F. Loss of BRCA1 impairs centromeric cohesion and triggers chromosomal instability. FASEB J. 2014, 28:5250-5261. 10.1096/fj.14-250266.
    • (2014) FASEB J. , vol.28 , pp. 5250-5261
    • Di Paolo, A.1    Racca, C.2    Calsou, P.3    Larminat, F.4
  • 36
    • 0034700134 scopus 로고    scopus 로고
    • The human SWI/SNF-B chromatin-remodeling complex is related to yeast Rsc and localizes at kinetochores of mitotic chromosomes
    • Xue Y., et al. The human SWI/SNF-B chromatin-remodeling complex is related to yeast Rsc and localizes at kinetochores of mitotic chromosomes. Proc. Natl. Acad. Sci. USA 2000, 97:13015-13020.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13015-13020
    • Xue, Y.1
  • 37
    • 67749108048 scopus 로고    scopus 로고
    • SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity
    • Bourgo R.J., et al. SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity. Mol. Biol. Cell 2009, 20:3192-3199. 10.1091/mbc.E08-12-1224.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 3192-3199
    • Bourgo, R.J.1
  • 38
    • 38749117849 scopus 로고    scopus 로고
    • Loss of ATRX leads to chromosome cohesion and congression defects
    • Ritchie K., et al. Loss of ATRX leads to chromosome cohesion and congression defects. J. Cell Biol. 2008, 180:315-324. 10.1083/jcb.200706083.
    • (2008) J. Cell Biol. , vol.180 , pp. 315-324
    • Ritchie, K.1
  • 39
    • 77954522274 scopus 로고    scopus 로고
    • Loss of pRB causes centromere dysfunction and chromosomal instability
    • Manning A.L., Longworth M.S., Dyson, NJ Loss of pRB causes centromere dysfunction and chromosomal instability. Genes Dev. 2010, 24:1364-1376. 10.1101/gad.1917310.
    • (2010) Genes Dev. , vol.24 , pp. 1364-1376
    • Manning, A.L.1    Longworth, M.S.2    Dyson, N.J.3
  • 41
    • 84938213091 scopus 로고    scopus 로고
    • Distinct functions of human cohesin-SA1 and cohesin-SA2 in DSB repair
    • Kong X., et al. Distinct functions of human cohesin-SA1 and cohesin-SA2 in DSB repair. Molecular and Cellular Biology 2013, 1:503-513. 10.1128/MCB.
    • (2013) Molecular and Cellular Biology , vol.1 , pp. 503-513
    • Kong, X.1
  • 42
    • 84858000859 scopus 로고    scopus 로고
    • APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer
    • Brough R., et al. APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer. EMBO J. 2012, 31:1160-1176. 10.1038/emboj.2011.490.
    • (2012) EMBO J. , vol.31 , pp. 1160-1176
    • Brough, R.1
  • 43
    • 84878400830 scopus 로고    scopus 로고
    • BAF complexes facilitate decatenation of DNA by topoisomerase IIalpha
    • Dykhuizen E.C., et al. BAF complexes facilitate decatenation of DNA by topoisomerase IIalpha. Nature 2013, 497:624-627. 10.1038/nature12146.
    • (2013) Nature , vol.497 , pp. 624-627
    • Dykhuizen, E.C.1
  • 44
    • 34548692558 scopus 로고    scopus 로고
    • Inhibition of transcription at radiation-induced nuclear foci of phosphorylated histone H2AX in mammalian cells
    • Solovjeva L.V., Svetlova M.P., Chagin V.O., Tomilin, NV Inhibition of transcription at radiation-induced nuclear foci of phosphorylated histone H2AX in mammalian cells. Chromosome Res. 2007, 15:787-797. 10.1007/s10577-007-1162-x.
    • (2007) Chromosome Res. , vol.15 , pp. 787-797
    • Solovjeva, L.V.1    Svetlova, M.P.2    Chagin, V.O.3    Tomilin, N.V.4
  • 45
    • 34250022502 scopus 로고    scopus 로고
    • The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks
    • Kruhlak M., et al. The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature 2007, 447:730-734. 10.1038/nature05842.
    • (2007) Nature , vol.447 , pp. 730-734
    • Kruhlak, M.1
  • 46
    • 50849104569 scopus 로고    scopus 로고
    • Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
    • O'Hagan H.M., Mohammad H.P., Baylin, SB Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. PLoS Genet 2008, 4:e1000155. 10.1371/journal.pgen.1000155.
    • (2008) PLoS Genet , vol.4 , pp. e1000155
    • O'Hagan, H.M.1    Mohammad, H.P.2    Baylin, S.B.3
  • 47
    • 78649349810 scopus 로고    scopus 로고
    • A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
    • Chou D.M., et al. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc. Natl. Acad. Sci. USA 2010, 107:18475-18480. 10.1073/pnas.1012946107.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 18475-18480
    • Chou, D.M.1
  • 48
    • 77953720192 scopus 로고    scopus 로고
    • ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
    • Shanbhag N.M., Rafalska-Metcalf I.U., Balane-Bolivar C., Janicki S.M., Greenberg, RA ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 2010, 141:970-981. 10.1016/j.cell.2010.04.038.
    • (2010) Cell , vol.141 , pp. 970-981
    • Shanbhag, N.M.1    Rafalska-Metcalf, I.U.2    Balane-Bolivar, C.3    Janicki, S.M.4    Greenberg, R.A.5
  • 49
    • 82955249089 scopus 로고    scopus 로고
    • Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4
    • Seiler D.M., et al. Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4. Chromosome Res. 2011, 19:883-899. 10.1007/s10577-011-9244-1.
    • (2011) Chromosome Res. , vol.19 , pp. 883-899
    • Seiler, D.M.1
  • 50
    • 84919451538 scopus 로고    scopus 로고
    • Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin
    • Kakarougkas A., et al. Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin. Mol. Cell 2014, 55:723-732. 10.1016/j.molcel.2014.06.028.
    • (2014) Mol. Cell , vol.55 , pp. 723-732
    • Kakarougkas, A.1
  • 51
    • 71249101060 scopus 로고    scopus 로고
    • Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
    • Lin C., et al. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell 2009, 139:1069-1083. 10.1016/j.cell.2009.11.030.
    • (2009) Cell , vol.139 , pp. 1069-1083
    • Lin, C.1
  • 52
    • 65249165421 scopus 로고    scopus 로고
    • Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma
    • Mathas S., et al. Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma. Proc. Natl. Acad. Sci. USA 2009, 106:5831-5836. 10.1073/pnas.0900912106.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 5831-5836
    • Mathas, S.1
  • 53
    • 84860338675 scopus 로고    scopus 로고
    • R loops: from transcription byproducts to threats to genome stability
    • Aguilera A., Garcia-Muse T. R loops: from transcription byproducts to threats to genome stability. Mol. Cell 2012, 46:115-124. 10.1016/j.molcel.2012.04.009.
    • (2012) Mol. Cell , vol.46 , pp. 115-124
    • Aguilera, A.1    Garcia-Muse, T.2
  • 54
    • 84918791689 scopus 로고    scopus 로고
    • Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability
    • Sollier J., et al. Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability. Mol. Cell 2014, 56:777-785. 10.1016/j.molcel.2014.10.020.
    • (2014) Mol. Cell , vol.56 , pp. 777-785
    • Sollier, J.1
  • 55
    • 84862829622 scopus 로고    scopus 로고
    • DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks
    • Pankotai T., Bonhomme C., Chen D., Soutoglou E. DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks. Nat. Struct. Mol. Biol. 2012, 19:276-282. 10.1038/nsmb.2224.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 276-282
    • Pankotai, T.1    Bonhomme, C.2    Chen, D.3    Soutoglou, E.4
  • 56
    • 84879643314 scopus 로고    scopus 로고
    • Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes
    • Schaaf C.A., et al. Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes. PLoS Genet. 2013, 9:e003560. 10.1371/journal.pgen.1003560.
    • (2013) PLoS Genet. , vol.9 , pp. e003560
    • Schaaf, C.A.1
  • 57
    • 79960305467 scopus 로고    scopus 로고
    • Nonallelic transcriptional roles of CTCF and cohesins at imprinted loci
    • 1449-10
    • Lin S., Ferguson-Smith A.C., Schultz R.M., Bartolomei M.S. Nonallelic transcriptional roles of CTCF and cohesins at imprinted loci. Mol. Cell. Biol. 2011, 31:3094-3104. 1449-10. 10.1128/MCB.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 3094-3104
    • Lin, S.1    Ferguson-Smith, A.C.2    Schultz, R.M.3    Bartolomei, M.S.4
  • 58
    • 0037667702 scopus 로고    scopus 로고
    • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
    • Narita M., et al. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 2003, 113:703-716.
    • (2003) Cell , vol.113 , pp. 703-716
    • Narita, M.1
  • 59
    • 84876431455 scopus 로고    scopus 로고
    • BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss
    • 1744-12
    • Tu Z., Zhuang X., Yao Y.G., Zhang R. BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss. Mol. Cell. Biol. 2013, 33:1819-1829. 1744-12. 10.1128/MCB.
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 1819-1829
    • Tu, Z.1    Zhuang, X.2    Yao, Y.G.3    Zhang, R.4
  • 60
    • 0034697973 scopus 로고    scopus 로고
    • BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer
    • Bochar D.A., et al. BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell 2000, 102:257-265.
    • (2000) Cell , vol.102 , pp. 257-265
    • Bochar, D.A.1
  • 61
    • 0028060515 scopus 로고
    • The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
    • Dunaief J.L., et al. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 1994, 79:119-130.
    • (1994) Cell , vol.79 , pp. 119-130
    • Dunaief, J.L.1
  • 62
    • 84864746573 scopus 로고    scopus 로고
    • A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers
    • Lee R.S., et al. A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. J. Clin. Invest. 2012, 122:2983-2988. 10.1172/JCI64400.
    • (2012) J. Clin. Invest. , vol.122 , pp. 2983-2988
    • Lee, R.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.