APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer

EMBO Journal

Volumn 31, Issue 5, 2012, Pages 1160-1176

  Brough, Rachel ^a,b   Bajrami, Ilirjana ^a,b   Vatcheva, Radost ^b   Natrajan, Rachael ^b   Reis Filho, Jorge S ^b   Lord, Christopher J ^b   Ashworth, Alan ^a,b  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

BRCA2; breast cancer; DNA repair

Indexed keywords

ANTINEOPLASTIC AGENT; APHIDICOLIN; BRCA2 PROTEIN; CELL CYCLE PROTEIN; COHESIN; CYCLINE; HYDROXYUREA; MITOMYCIN C; MYC PROTEIN; PROTEIN APRIN; PROTEIN CDC45; PROTEIN RAD21; PROTEIN SMC3; PROTEIN VARIANT; RAD51 PROTEIN; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRCA2 ONCOGENE; BREAST CANCER; CANCER GRADING; CANCER PATIENT; CANCER RISK; CONTROLLED STUDY; GENE MUTATION; GENOME; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; MISSENSE MUTATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; TREATMENT OUTCOME;

ANTINEOPLASTIC AGENTS; BRCA2 PROTEIN; BREAST NEOPLASMS; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; DRUG THERAPY; HUMANS; PROGNOSIS; PROTEIN INTERACTION MAPPING; PROTEOME; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; TRANSCRIPTION FACTORS; TREATMENT OUTCOME;

EID: 84858000859     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.490     Document Type: Article

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