-
1
-
-
84871099014
-
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
-
23245608
-
Murray CJ, Vos T, Lozano R, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2197-223.
-
(2012)
Lancet
, vol.380
, pp. 2197-2223
-
-
Murray, C.J.1
Vos, T.2
Lozano, R.3
-
2
-
-
0026529131
-
Prevalence of migraine headache in the United States. Relation to age, income, race and other sociodemographic factors
-
1:STN:280:DyaK38%2FnvFeksA%3D%3D 1727198
-
Stewart WF, Lipton RB, Celentano DD, Reed ML. Prevalence of migraine headache in the United States. Relation to age, income, race and other sociodemographic factors. JAMA. 1992;267:64-9.
-
(1992)
JAMA
, vol.267
, pp. 64-69
-
-
Stewart, W.F.1
Lipton, R.B.2
Celentano, D.D.3
Reed, M.L.4
-
3
-
-
84879990242
-
The international classification of headache disorders, 3rd edition (beta version)
-
Headache Classification Committee of the International Headache Society (IHS). The international classification of headache disorders, 3rd edition (beta version). Cephalalgia 2013;33:629-808.
-
(2013)
Cephalalgia
, vol.33
, pp. 629-808
-
-
-
4
-
-
79551544583
-
Acute migraine therapy: new drugs and new approaches
-
3016076 21110235
-
Monteith TS, Goadsby PJ. Acute migraine therapy: new drugs and new approaches. Curr Treat Options Neurol. 2011;13:1-14.
-
(2011)
Curr Treat Options Neurol
, vol.13
, pp. 1-14
-
-
Monteith, T.S.1
Goadsby, P.J.2
-
5
-
-
0043029861
-
Sumatriptan plus metoclopramide in triptan-nonresponsive migraineurs
-
12890127
-
Schulman EA, Dermott KF. Sumatriptan plus metoclopramide in triptan-nonresponsive migraineurs. Headache. 2003;43:729-33.
-
(2003)
Headache
, vol.43
, pp. 729-733
-
-
Schulman, E.A.1
Dermott, K.F.2
-
6
-
-
2542432259
-
Cardiovascular risk assessment and triptans
-
15149491
-
Papademetriou V. Cardiovascular risk assessment and triptans. Headache. 2004;44(Suppl 1):S31-9.
-
(2004)
Headache
, vol.44
, pp. S31-S39
-
-
Papademetriou, V.1
-
7
-
-
0037165257
-
Migraine-current understanding and treatment
-
1:CAS:528:DC%2BD38XmslGgsQ%3D%3D 11807151
-
Goadsby PJ, Lipton RB, Ferrari MD. Migraine-current understanding and treatment. N Engl J Med. 2002;346:257-70.
-
(2002)
N Engl J Med
, vol.346
, pp. 257-270
-
-
Goadsby, P.J.1
Lipton, R.B.2
Ferrari, M.D.3
-
8
-
-
84893930874
-
Preventive pharmacotherapy in migraine
-
24261479
-
Rizzoli P. Preventive pharmacotherapy in migraine. Headache. 2014;54:364-9.
-
(2014)
Headache
, vol.54
, pp. 364-369
-
-
Rizzoli, P.1
-
9
-
-
84894169671
-
Therapeutic prospects for migraine: can paradise be regained?
-
1:CAS:528:DC%2BC3sXhs1WntrfE 25813389
-
Goadsby PJ. Therapeutic prospects for migraine: can paradise be regained? Ann Neurol. 2013;74:423-34.
-
(2013)
Ann Neurol
, vol.74
, pp. 423-434
-
-
Goadsby, P.J.1
-
10
-
-
84929345915
-
Therapeutic antibodies against CGRP or its receptor
-
1:CAS:528:DC%2BC2MXptFKrs7w%3D 25614243
-
Bigal ME, Walter S, Rapoport AM. Therapeutic antibodies against CGRP or its receptor. Br J Clin Pharmacol. 2015;79:886-95.
-
(2015)
Br J Clin Pharmacol
, vol.79
, pp. 886-895
-
-
Bigal, M.E.1
Walter, S.2
Rapoport, A.M.3
-
11
-
-
84860767840
-
Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society
-
1:CAS:528:DC%2BC38XmtVGktrw%3D 3335452 22529202
-
Silberstein SD, Holland S, Freitag F, Dodick DW, Argoff C, Ashman E. Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology. 2012;78:1337-45.
-
(2012)
Neurology
, vol.78
, pp. 1337-1345
-
-
Silberstein, S.D.1
Holland, S.2
Freitag, F.3
Dodick, D.W.4
Argoff, C.5
Ashman, E.6
-
12
-
-
84921297497
-
The therapeutic armamentarium in migraine is quite elderly
-
1:CAS:528:DC%2BC2MXhtlGktb4%3D 25435318
-
Martelletti P. The therapeutic armamentarium in migraine is quite elderly. Expert Opin Drug Metab Toxicol. 2015;11:175-7.
-
(2015)
Expert Opin Drug Metab Toxicol
, vol.11
, pp. 175-177
-
-
Martelletti, P.1
-
15
-
-
4043057222
-
Blockade of CGRP receptors in the intracranial vasculature: a new target in the treatment of headache
-
1:STN:280:DC%2BD2czmt1SnsQ%3D%3D 15265049
-
Edvinsson L. Blockade of CGRP receptors in the intracranial vasculature: a new target in the treatment of headache. Cephalalgia. 2004;24:611-22.
-
(2004)
Cephalalgia
, vol.24
, pp. 611-622
-
-
Edvinsson, L.1
-
16
-
-
27744558554
-
Unitary hypothesis for multiple triggers of the pain and strain of migraine
-
16258903
-
Burstein R, Jakubowski M. Unitary hypothesis for multiple triggers of the pain and strain of migraine. J Comp Neurol. 2005;493:9-14.
-
(2005)
J Comp Neurol
, vol.493
, pp. 9-14
-
-
Burstein, R.1
Jakubowski, M.2
-
17
-
-
0025753228
-
Stimulation of the superior sagittal sinus increases metabolic activity and blood flow in certain regions of the brainstem and upper cervical spinal cord of the cat
-
2043937
-
Goadsby PJ, Zagami AS. Stimulation of the superior sagittal sinus increases metabolic activity and blood flow in certain regions of the brainstem and upper cervical spinal cord of the cat. Brain. 1991;114:1001-11.
-
(1991)
Brain
, vol.114
, pp. 1001-1011
-
-
Goadsby, P.J.1
Zagami, A.S.2
-
18
-
-
0026180255
-
Neural processing of craniovascular pain: synthesis of the central structures involved in migraine
-
1:STN:280:DyaK3MzmsFKjsg%3D%3D 1889975
-
Goadsby PJ, Zagami AS, Lambert GA. Neural processing of craniovascular pain: synthesis of the central structures involved in migraine. Headache. 1991;31:365-71.
-
(1991)
Headache
, vol.31
, pp. 365-371
-
-
Goadsby, P.J.1
Zagami, A.S.2
Lambert, G.A.3
-
19
-
-
0030859623
-
Stimulation of the greater occipital nerve increases metabolic activity in the trigeminal nucleus caudalis and cervical dorsal horn of the cat
-
1:CAS:528:DyaK2sXms1eqtrg%3D 9414053
-
Goadsby PJ, Hoskin KL, Knight YE. Stimulation of the greater occipital nerve increases metabolic activity in the trigeminal nucleus caudalis and cervical dorsal horn of the cat. Pain. 1997;73:23-8.
-
(1997)
Pain
, vol.73
, pp. 23-28
-
-
Goadsby, P.J.1
Hoskin, K.L.2
Knight, Y.E.3
-
20
-
-
77953273344
-
Calcitonin gene-related peptide (CGRP) receptor antagonists in the treatment of migraine
-
1:CAS:528:DC%2BC3cXpsFajs7Y%3D 3138175 20433208
-
Durham PL, Vause CV. Calcitonin gene-related peptide (CGRP) receptor antagonists in the treatment of migraine. CNS Drugs. 2010;24:539-48.
-
(2010)
CNS Drugs
, vol.24
, pp. 539-548
-
-
Durham, P.L.1
Vause, C.V.2
-
21
-
-
84897555348
-
The vasodilatory activity of CGRP: a response
-
24697226
-
Bigal ME, Walter S, Rapoport AM. The vasodilatory activity of CGRP: a response. Headache. 2014;54:748-9.
-
(2014)
Headache
, vol.54
, pp. 748-749
-
-
Bigal, M.E.1
Walter, S.2
Rapoport, A.M.3
-
22
-
-
0025143541
-
Vasoactive peptide release in the extracerebral circulation of humans during migraine headache
-
1:STN:280:DyaK3M%2FisVSktQ%3D%3D 1699472
-
Goadsby PJ, Edvinsson L, Ekman R. Vasoactive peptide release in the extracerebral circulation of humans during migraine headache. Ann Neurol. 1990;28:183-7.
-
(1990)
Ann Neurol
, vol.28
, pp. 183-187
-
-
Goadsby, P.J.1
Edvinsson, L.2
Ekman, R.3
-
24
-
-
0036285460
-
CGRP may play a causative role in migraine
-
1:STN:280:DC%2BD383ltlGrtA%3D%3D 11993614
-
Lassen LH, Haderslev PA, Jacobsen VB, Iversen HK, Sperling B, Olesen J. CGRP may play a causative role in migraine. Cephalalgia. 2002;22:54-61.
-
(2002)
Cephalalgia
, vol.22
, pp. 54-61
-
-
Lassen, L.H.1
Haderslev, P.A.2
Jacobsen, V.B.3
Iversen, H.K.4
Sperling, B.5
Olesen, J.6
-
25
-
-
78650413846
-
Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura
-
20855363
-
Hansen JM, Hauge AW, Olesen J, Ashina M. Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura. Cephalalgia. 2010;30:1179-86.
-
(2010)
Cephalalgia
, vol.30
, pp. 1179-1186
-
-
Hansen, J.M.1
Hauge, A.W.2
Olesen, J.3
Ashina, M.4
-
26
-
-
70349899104
-
Elevated saliva calcitonin gene-related peptide levels during acute migraine predict therapeutic response to rizatriptan
-
19788468
-
Cady RK, Vause CV, Ho TW, Bigal ME, Durham PL. Elevated saliva calcitonin gene-related peptide levels during acute migraine predict therapeutic response to rizatriptan. Headache. 2009;49:1258-66.
-
(2009)
Headache
, vol.49
, pp. 1258-1266
-
-
Cady, R.K.1
Vause, C.V.2
Ho, T.W.3
Bigal, M.E.4
Durham, P.L.5
-
27
-
-
0020607936
-
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing
-
1:CAS:528:DyaL3sXlslSmtrs%3D 6346105
-
Rosenfeld MG, Mermod JJ, Amara SG, et al. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature. 1983;304:129-35.
-
(1983)
Nature
, vol.304
, pp. 129-135
-
-
Rosenfeld, M.G.1
Mermod, J.J.2
Amara, S.G.3
-
28
-
-
0036266044
-
International union of pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors
-
1:CAS:528:DC%2BD38XltVOiu7o%3D 12037140
-
Poyner DR, Sexton PM, Marshall I, et al. International union of pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol Rev. 2002;54:233-46.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 233-246
-
-
Poyner, D.R.1
Sexton, P.M.2
Marshall, I.3
-
29
-
-
34548688477
-
Evolution of the CT/CGRP family: comparative study with new data from models of teleosts, the eel, and cephalopod molluscs, the cuttlefish and the nautilus
-
1:CAS:528:DC%2BD2sXotlSitb4%3D 17353015
-
Lafont AG, Dufour S, Fouchereau-Peron M. Evolution of the CT/CGRP family: comparative study with new data from models of teleosts, the eel, and cephalopod molluscs, the cuttlefish and the nautilus. Gen Comp Endocrinol. 2007;153:155-69.
-
(2007)
Gen Comp Endocrinol
, vol.153
, pp. 155-169
-
-
Lafont, A.G.1
Dufour, S.2
Fouchereau-Peron, M.3
-
30
-
-
69249202445
-
alphaCGRP and betaCGRP transcript amount in mouse tissues of various developmental stages and their tissue expression sites
-
19062206
-
Rezaeian AH, Isokane T, Nishibori M, et al. alphaCGRP and betaCGRP transcript amount in mouse tissues of various developmental stages and their tissue expression sites. Brain Dev. 2009;31:682-93.
-
(2009)
Brain Dev
, vol.31
, pp. 682-693
-
-
Rezaeian, A.H.1
Isokane, T.2
Nishibori, M.3
-
31
-
-
0036671940
-
Interaction of calcitonin-gene-related peptide with its receptors
-
1:CAS:528:DC%2BD38XntVensL4%3D 12196113
-
Conner AC, Hay DL, Howitt SG, et al. Interaction of calcitonin-gene-related peptide with its receptors. Biochem Soc Trans. 2002;30:451-5.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 451-455
-
-
Conner, A.C.1
Hay, D.L.2
Howitt, S.G.3
-
32
-
-
0026768337
-
Enteric and visceral afferent CGRP neurons. Targets of innervation and differential expression patterns
-
1:CAS:528:DyaK38Xls1eqtr0%3D 1637083
-
Sternini C. Enteric and visceral afferent CGRP neurons. Targets of innervation and differential expression patterns. Ann N Y Acad Sci. 1992;657:170-86.
-
(1992)
Ann N Y Acad Sci
, vol.657
, pp. 170-186
-
-
Sternini, C.1
-
33
-
-
0030665019
-
Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors
-
9353797
-
van Rossum D, Hanisch UK, Quirion R. Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors. Neurosci Biobehav Rev. 1997;21:649-78.
-
(1997)
Neurosci Biobehav Rev
, vol.21
, pp. 649-678
-
-
Van Rossum, D.1
Hanisch, U.K.2
Quirion, R.3
-
34
-
-
84920824222
-
Calcitonin gene-related peptide (CGRP): a new target for migraine
-
1:CAS:528:DC%2BC2MXkt12qsLw%3D 25340934
-
Russo AF. Calcitonin gene-related peptide (CGRP): a new target for migraine. Annu Rev Pharmacol Toxicol. 2015;55:533-52.
-
(2015)
Annu Rev Pharmacol Toxicol
, vol.55
, pp. 533-552
-
-
Russo, A.F.1
-
35
-
-
33847671313
-
Inhibitory effect of BIBN4096BS, CGRP(8-37), a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery
-
1:CAS:528:DC%2BD2sXisVeisL8%3D 2189771 17245362
-
Edvinsson L, Nilsson E, Jansen-Olesen I. Inhibitory effect of BIBN4096BS, CGRP(8-37), a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery. Br J Pharmacol. 2007;150:633-40.
-
(2007)
Br J Pharmacol
, vol.150
, pp. 633-640
-
-
Edvinsson, L.1
Nilsson, E.2
Jansen-Olesen, I.3
-
36
-
-
84857084559
-
Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation
-
3383830 22123247
-
Raddant AC, Russo AF. Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation. Expert Rev Mol Med. 2011;13:e36.
-
(2011)
Expert Rev Mol Med
, vol.13
, pp. e36
-
-
Raddant, A.C.1
Russo, A.F.2
-
37
-
-
0004954443
-
Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary
-
1:CAS:528:DyaL2MXptVChsg%3D%3D 397010 2578663
-
Tschopp FA, Henke H, Petermann JB, et al. Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary. Proc Natl Acad Sci USA. 1985;82:248-52.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 248-252
-
-
Tschopp, F.A.1
Henke, H.2
Petermann, J.B.3
-
38
-
-
0029969026
-
Calcitonin gene-related peptide and its receptors: molecular genetics, physiology, pathophysiology, and therapeutic potentials
-
1:CAS:528:DyaK28XmvF2hs7Y%3D 8897024
-
Wimalawansa SJ. Calcitonin gene-related peptide and its receptors: molecular genetics, physiology, pathophysiology, and therapeutic potentials. Endocr Rev. 1996;17:533-85.
-
(1996)
Endocr Rev
, vol.17
, pp. 533-585
-
-
Wimalawansa, S.J.1
-
39
-
-
77957922955
-
CGRP and its receptors provide new insights into migraine pathophysiology
-
1:CAS:528:DC%2BC3cXht1Gku7bI 20820195
-
Ho TW, Edvinsson L, Goadsby PJ. CGRP and its receptors provide new insights into migraine pathophysiology. Nat Rev Neurol. 2010;6:573-82.
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 573-582
-
-
Ho, T.W.1
Edvinsson, L.2
Goadsby, P.J.3
-
40
-
-
0021934415
-
Topographic localization of calcitonin gene-related peptide in the rat brain: an immunohistochemical analysis
-
1:STN:280:DyaL28%2FmsFOqtA%3D%3D 3877882
-
Kawai Y, Takami K, Shiosaka S, et al. Topographic localization of calcitonin gene-related peptide in the rat brain: an immunohistochemical analysis. Neuroscience. 1985;15:747-63.
-
(1985)
Neuroscience
, vol.15
, pp. 747-763
-
-
Kawai, Y.1
Takami, K.2
Shiosaka, S.3
-
41
-
-
0022369132
-
Quantitative distribution of calcitonin gene-related peptide in the rat central nervous system
-
1:CAS:528:DyaL28XhsValsbg%3D 3879634
-
Skofitsch G, Jacobowitz DM. Quantitative distribution of calcitonin gene-related peptide in the rat central nervous system. Peptides. 1985;6:1069-73.
-
(1985)
Peptides
, vol.6
, pp. 1069-1073
-
-
Skofitsch, G.1
Jacobowitz, D.M.2
-
42
-
-
84892444332
-
Localization of CGRP receptor components, CGRP, and receptor binding sites in human and rhesus cerebellar cortex
-
1:CAS:528:DC%2BC3sXhs1Krs7%2FN 23917876
-
Eftekhari S, Salvatore CA, Gaspar RC, et al. Localization of CGRP receptor components, CGRP, and receptor binding sites in human and rhesus cerebellar cortex. Cerebellum. 2013;12:937-49.
-
(2013)
Cerebellum
, vol.12
, pp. 937-949
-
-
Eftekhari, S.1
Salvatore, C.A.2
Gaspar, R.C.3
-
43
-
-
84923335592
-
Localization of CGRP, CGRP receptor, PACAP and glutamate in trigeminal ganglion. Relation to the blood-brain barrier
-
1:CAS:528:DC%2BC2cXitVWktLjI 25463029
-
Eftekhari S, Salvatore CA, Johansson S, Chen TB, Zeng Z, Edvinsson L. Localization of CGRP, CGRP receptor, PACAP and glutamate in trigeminal ganglion. Relation to the blood-brain barrier. Brain Res. 2015;1600:93-109.
-
(2015)
Brain Res
, vol.1600
, pp. 93-109
-
-
Eftekhari, S.1
Salvatore, C.A.2
Johansson, S.3
Chen, T.B.4
Zeng, Z.5
Edvinsson, L.6
-
44
-
-
84887084591
-
Differentiation of nerve fibers storing CGRP and CGRP receptors in the peripheral trigeminovascular system
-
1:CAS:528:DC%2BC3sXht12itbnI 23958278
-
Eftekhari S, Warfvinge K, Blixt FW, Edvinsson L. Differentiation of nerve fibers storing CGRP and CGRP receptors in the peripheral trigeminovascular system. J Pain. 2013;14:1289-303.
-
(2013)
J Pain
, vol.14
, pp. 1289-1303
-
-
Eftekhari, S.1
Warfvinge, K.2
Blixt, F.W.3
Edvinsson, L.4
-
45
-
-
81055126935
-
Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level
-
1:CAS:528:DC%2BC38XktVOksr0%3D 3282678 22074408
-
Eftekhari S, Edvinsson L. Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nucleus and spinal cord at C1-level. BMC Neurosci. 2011;12:112.
-
(2011)
BMC Neurosci
, vol.12
, pp. 112
-
-
Eftekhari, S.1
Edvinsson, L.2
-
46
-
-
0022493602
-
Calcitonin gene-related peptide: novel neuropeptide
-
1:CAS:528:DyaL28XktFylsr4%3D 2423836
-
Goodman EC, Iversen LL. Calcitonin gene-related peptide: novel neuropeptide. Life Sci. 1986;38:2169-78.
-
(1986)
Life Sci
, vol.38
, pp. 2169-2178
-
-
Goodman, E.C.1
Iversen, L.L.2
-
47
-
-
0036676378
-
Calcitonin gene-related peptide in pregnancy and its emerging receptor heterogeneity
-
1:CAS:528:DC%2BD38XlsVOktro%3D 12128288
-
Yallampalli C, Chauhan M, Thota CS, Kondapaka S, Wimalawansa SJ. Calcitonin gene-related peptide in pregnancy and its emerging receptor heterogeneity. Trends Endocrinol Metab. 2002;13:263-9.
-
(2002)
Trends Endocrinol Metab
, vol.13
, pp. 263-269
-
-
Yallampalli, C.1
Chauhan, M.2
Thota, C.S.3
Kondapaka, S.4
Wimalawansa, S.J.5
-
48
-
-
0033707952
-
Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists
-
1:CAS:528:DC%2BD3cXotFemsLg%3D 1572412 11053206
-
Powell KJ, Ma W, Sutak M, Doods H, Quirion R, Jhamandas K. Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists. Br J Pharmacol. 2000;131:875-84.
-
(2000)
Br J Pharmacol
, vol.131
, pp. 875-884
-
-
Powell, K.J.1
Ma, W.2
Sutak, M.3
Doods, H.4
Quirion, R.5
Jhamandas, K.6
-
49
-
-
0023143665
-
Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats
-
1:CAS:528:DyaL2sXhtlahtr0%3D 2435372
-
Oku R, Satoh M, Fujii N, Otaka A, Yajima H, Takagi H. Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats. Brain Res. 1987;403:350-4.
-
(1987)
Brain Res
, vol.403
, pp. 350-354
-
-
Oku, R.1
Satoh, M.2
Fujii, N.3
Otaka, A.4
Yajima, H.5
Takagi, H.6
-
50
-
-
34547787129
-
Calcitonin receptor-like receptor and receptor activity modifying protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic alpha2C receptors
-
1:CAS:528:DC%2BD2sXovFOrtLs%3D 2329818 17614212
-
Marvizon JC, Perez OA, Song B, et al. Calcitonin receptor-like receptor and receptor activity modifying protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic alpha2C receptors. Neuroscience. 2007;148:250-65.
-
(2007)
Neuroscience
, vol.148
, pp. 250-265
-
-
Marvizon, J.C.1
Perez, O.A.2
Song, B.3
-
51
-
-
70349934573
-
The role of peptides in central sensitization
-
1:CAS:528:DC%2BC3cXjvV2gug%3D%3D 19655115
-
Seybold VS. The role of peptides in central sensitization. Handb Exp Pharmacol 2009;194:451-91.
-
(2009)
Handb Exp Pharmacol
, vol.194
, pp. 451-491
-
-
Seybold, V.S.1
-
52
-
-
0041589351
-
Localization of the calcitonin gene-related peptide receptor complex at the vertebrate neuromuscular junction and its role in regulating acetylcholinesterase expression
-
1:CAS:528:DC%2BD3sXltVSlsb0%3D 12707285
-
Rossi SG, Dickerson IM, Rotundo RL. Localization of the calcitonin gene-related peptide receptor complex at the vertebrate neuromuscular junction and its role in regulating acetylcholinesterase expression. J Biol Chem. 2003;278:24994-5000.
-
(2003)
J Biol Chem
, vol.278
, pp. 24994-25000
-
-
Rossi, S.G.1
Dickerson, I.M.2
Rotundo, R.L.3
-
53
-
-
0030983609
-
Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide
-
1:STN:280:DyaK2szhtl2gug%3D%3D 9170339
-
Ottosson A, Edvinsson L. Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide. Cephalalgia. 1997;17:166-74.
-
(1997)
Cephalalgia
, vol.17
, pp. 166-174
-
-
Ottosson, A.1
Edvinsson, L.2
-
54
-
-
0028806454
-
Calcitonin gene related peptide released from dural nerve fibers mediates increase of meningeal blood flow in the rat
-
1:CAS:528:DyaK2MXoslCjs70%3D 8846394
-
Messlinger K, Hanesch U, Kurosawa M, Pawlak M, Schmidt RF. Calcitonin gene related peptide released from dural nerve fibers mediates increase of meningeal blood flow in the rat. Can J Physiol Pharmacol. 1995;73:1020-4.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 1020-1024
-
-
Messlinger, K.1
Hanesch, U.2
Kurosawa, M.3
Pawlak, M.4
Schmidt, R.F.5
-
55
-
-
0029847688
-
Sensitization of meningeal sensory neurons and the origin of headaches
-
1:CAS:528:DyaK2sXhtlWh 8955268
-
Strassman AM, Raymond SA, Burstein R. Sensitization of meningeal sensory neurons and the origin of headaches. Nature. 1996;384:560-4.
-
(1996)
Nature
, vol.384
, pp. 560-564
-
-
Strassman, A.M.1
Raymond, S.A.2
Burstein, R.3
-
56
-
-
34447345940
-
Neuron-glia signaling in trigeminal ganglion: implications for migraine pathology
-
2268711 17635592
-
Thalakoti S, Patil VV, Damodaram S, et al. Neuron-glia signaling in trigeminal ganglion: implications for migraine pathology. Headache. 2007;47:1008-23.
-
(2007)
Headache
, vol.47
, pp. 1008-1023
-
-
Thalakoti, S.1
Patil, V.V.2
Damodaram, S.3
-
57
-
-
67650502716
-
Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine
-
1:CAS:528:DC%2BD1MXovVKgsr8%3D 2944225 19587287
-
Recober A, Kuburas A, Zhang Z, Wemmie JA, Anderson MG, Russo AF. Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine. J Neurosci. 2009;29:8798-804.
-
(2009)
J Neurosci
, vol.29
, pp. 8798-8804
-
-
Recober, A.1
Kuburas, A.2
Zhang, Z.3
Wemmie, J.A.4
Anderson, M.G.5
Russo, A.F.6
-
58
-
-
46949111401
-
International Union of Pharmacology. LXIX. Status of the calcitonin gene-related peptide subtype 2 receptor
-
18552275
-
Hay DL, Poyner DR, Quirion R. International Union of Pharmacology. LXIX. Status of the calcitonin gene-related peptide subtype 2 receptor. Pharmacol Rev. 2008;60:143-5.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 143-145
-
-
Hay, D.L.1
Poyner, D.R.2
Quirion, R.3
-
59
-
-
0026342822
-
Expression cloning of an adenylate cyclase-coupled calcitonin receptor
-
1:CAS:528:DyaK3sXhs1Whsrc%3D 1658940
-
Lin HY, Harris TL, Flannery MS, et al. Expression cloning of an adenylate cyclase-coupled calcitonin receptor. Science. 1991;254:1022-4.
-
(1991)
Science
, vol.254
, pp. 1022-1024
-
-
Lin, H.Y.1
Harris, T.L.2
Flannery, M.S.3
-
60
-
-
77956898559
-
Regulation of signal transduction by calcitonin gene-related peptide receptors
-
1:CAS:528:DC%2BC3cXht1Wisr%2FM 20633935
-
Walker CS, Conner AC, Poyner DR, Hay DL. Regulation of signal transduction by calcitonin gene-related peptide receptors. Trends Pharmacol Sci. 2010;31:476-83.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 476-483
-
-
Walker, C.S.1
Conner, A.C.2
Poyner, D.R.3
Hay, D.L.4
-
61
-
-
77956336134
-
Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism
-
20826335
-
ter Haar E, Koth CM, Abdul-Manan N, et al. Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism. Structure. 2010;18:1083-93.
-
(2010)
Structure
, vol.18
, pp. 1083-1093
-
-
Ter Haar, E.1
Koth, C.M.2
Abdul-Manan, N.3
-
62
-
-
55549092099
-
Crystal structure of the human receptor activity-modifying protein 1 extracellular domain
-
1:CAS:528:DC%2BD1cXhtlGlsb%2FO 2578806 18725456
-
Kusano S, Kukimoto-Niino M, Akasaka R, et al. Crystal structure of the human receptor activity-modifying protein 1 extracellular domain. Protein Sci. 2008;17:1907-14.
-
(2008)
Protein Sci
, vol.17
, pp. 1907-1914
-
-
Kusano, S.1
Kukimoto-Niino, M.2
Akasaka, R.3
-
63
-
-
0033054409
-
RAMPs: accessory proteins for seven transmembrane domain receptors
-
1:CAS:528:DyaK1MXksVent7w%3D 10354609
-
Foord SM, Marshall FH. RAMPs: accessory proteins for seven transmembrane domain receptors. Trends Pharmacol Sci. 1999;20:184-7.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 184-187
-
-
Foord, S.M.1
Marshall, F.H.2
-
64
-
-
33847790338
-
Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion
-
1:CAS:528:DC%2BD2sXjsVCrtbc%3D 17344407
-
Zhang Z, Winborn CS, de Marquez PB, Russo AF. Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion. J Neurosci. 2007;27:2693-703.
-
(2007)
J Neurosci
, vol.27
, pp. 2693-2703
-
-
Zhang, Z.1
Winborn, C.S.2
De Marquez, P.B.3
Russo, A.F.4
-
65
-
-
84887643807
-
CGRP in the trigeminovascular system: a role for CGRP, adrenomedullin and amylin receptors?
-
1:CAS:528:DC%2BC3sXhslOmtr7M 3838677 23425327
-
Walker CS, Hay DL. CGRP in the trigeminovascular system: a role for CGRP, adrenomedullin and amylin receptors? Br J Pharmacol. 2013;170:1293-307.
-
(2013)
Br J Pharmacol
, vol.170
, pp. 1293-1307
-
-
Walker, C.S.1
Hay, D.L.2
-
66
-
-
58149214226
-
Effect of adrenomedullin on the cerebral circulation: relevance to primary headache disorders
-
1:STN:280:DC%2BD1M%2FlsFKhsw%3D%3D 19126117
-
Petersen KA, Birk S, Kitamura K, Olesen J. Effect of adrenomedullin on the cerebral circulation: relevance to primary headache disorders. Cephalalgia. 2009;29:23-30.
-
(2009)
Cephalalgia
, vol.29
, pp. 23-30
-
-
Petersen, K.A.1
Birk, S.2
Kitamura, K.3
Olesen, J.4
-
68
-
-
84859727546
-
Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes
-
1:CAS:528:DC%2BC38XmsVaqsbc%3D 3415645 22014233
-
Bailey RJ, Walker CS, Ferner AH, et al. Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes. Br J Pharmacol. 2012;166:151-67.
-
(2012)
Br J Pharmacol
, vol.166
, pp. 151-167
-
-
Bailey, R.J.1
Walker, C.S.2
Ferner, A.H.3
-
69
-
-
17844365264
-
Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes
-
1:CAS:528:DC%2BD2MXktFegt7o%3D 15692146
-
Hay DL, Christopoulos G, Christopoulos A, Poyner DR, Sexton PM. Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes. Mol Pharmacol. 2005;67:1655-65.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1655-1665
-
-
Hay, D.L.1
Christopoulos, G.2
Christopoulos, A.3
Poyner, D.R.4
Sexton, P.M.5
-
70
-
-
84938212005
-
Function and expression of two calcitonin gene-related peptide receptors within the sensory trigeminal system
-
Valencia
-
Hay DL, Eftekhari S, Bower RL, Wilderman A, Insel PA, Edvinsson L, Waldvogel HJ, Russo AF, Caron KM, and Walker CS Function and expression of two calcitonin gene-related peptide receptors within the sensory trigeminal system. In: 17th Congress of the International Headache Society, Valencia, 2015.
-
(2015)
17th Congress of the International Headache Society
-
-
Hay, D.L.1
Eftekhari, S.2
Bower, R.L.3
Wilderman, A.4
Insel, P.A.5
Edvinsson, L.6
Waldvogel, H.J.7
Russo, A.F.8
Caron, K.M.9
Walker, C.S.10
-
71
-
-
0033970471
-
Pharmacological profile of BIBN-4096BS, the first selective small molecule CGRP antagonist
-
1:CAS:528:DC%2BD3cXht1ynsLc%3D 1571877 10711339
-
Doods H, Hallermayer G, Wu D, et al. Pharmacological profile of BIBN-4096BS, the first selective small molecule CGRP antagonist. Br J Pharmacol. 2000;129:420-3.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 420-423
-
-
Doods, H.1
Hallermayer, G.2
Wu, D.3
-
72
-
-
0024597810
-
Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37)
-
1:CAS:528:DyaL1MXhsVyguro%3D 2537579
-
Chiba T, Yamaguchi A, Yamatani T, et al. Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol. 1989;256:E331-5.
-
(1989)
Am J Physiol
, vol.256
, pp. E331-E335
-
-
Chiba, T.1
Yamaguchi, A.2
Yamatani, T.3
-
73
-
-
0037134498
-
Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists
-
1:CAS:528:DC%2BD38XjsFWnuro%3D 11847213
-
Mallee JJ, Salvatore CA, LeBourdelles B, et al. Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists. J Biol Chem. 2002;277:14294-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 14294-14298
-
-
Mallee, J.J.1
Salvatore, C.A.2
LeBourdelles, B.3
-
74
-
-
1542346238
-
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine
-
1:CAS:528:DC%2BD2cXitV2qur0%3D 15014183
-
Olesen J, Diener HC, Husstedt IW, et al. Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. N Engl J Med. 2004;350:1104-10.
-
(2004)
N Engl J Med
, vol.350
, pp. 1104-1110
-
-
Olesen, J.1
Diener, H.C.2
Husstedt, I.W.3
-
75
-
-
84901507463
-
Monoclonal antibodies for migraine: preventing calcitonin gene-related peptide activity
-
1:CAS:528:DC%2BC2cXosVWhtb4%3D 24638916
-
Bigal ME, Walter S. Monoclonal antibodies for migraine: preventing calcitonin gene-related peptide activity. CNS Drugs. 2014;28:389-99.
-
(2014)
CNS Drugs
, vol.28
, pp. 389-399
-
-
Bigal, M.E.1
Walter, S.2
-
76
-
-
33645886051
-
Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead
-
1:CAS:528:DC%2BD28XjtFGisL0%3D 16527483
-
Williams TM, Stump CA, Nguyen DN, et al. Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead. Bioorg Med Chem Lett. 2006;16:2595-8.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 2595-2598
-
-
Williams, T.M.1
Stump, C.A.2
Nguyen, D.N.3
-
77
-
-
49649114639
-
Synthesis of the (3R,6S)-3-amino-6-(2,3-difluorophenyl)azepan-2-one of telcagepant (MK-0974), a calcitonin gene-related peptide receptor antagonist for the treatment of migraine headache
-
1:CAS:528:DC%2BD1cXnvF2hurk%3D 18590336
-
Burgey CS, Paone DV, Shaw AW, et al. Synthesis of the (3R,6S)-3-amino-6-(2,3-difluorophenyl)azepan-2-one of telcagepant (MK-0974), a calcitonin gene-related peptide receptor antagonist for the treatment of migraine headache. Org Lett. 2008;10:3235-8.
-
(2008)
Org Lett
, vol.10
, pp. 3235-3238
-
-
Burgey, C.S.1
Paone, D.V.2
Shaw, A.W.3
-
78
-
-
78650938657
-
Antimigraine efficacy of telcagepant based on patient's historical triptan response
-
21054362
-
Ho TW, Olesen J, Dodick DW, Kost J, Lines C, Ferrari MD. Antimigraine efficacy of telcagepant based on patient's historical triptan response. Headache. 2011;51:64-72.
-
(2011)
Headache
, vol.51
, pp. 64-72
-
-
Ho, T.W.1
Olesen, J.2
Dodick, D.W.3
Kost, J.4
Lines, C.5
Ferrari, M.D.6
-
79
-
-
42249087655
-
Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine
-
1:CAS:528:DC%2BD1cXktlOhtLs%3D 17914062
-
Ho TW, Mannix LK, Fan X, et al. Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine. Neurology. 2008;70:1304-12.
-
(2008)
Neurology
, vol.70
, pp. 1304-1312
-
-
Ho, T.W.1
Mannix, L.K.2
Fan, X.3
-
80
-
-
57649233374
-
Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial
-
1:CAS:528:DC%2BD1cXhsFajs7nE 19036425
-
Ho TW, Ferrari MD, Dodick DW, et al. Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial. Lancet. 2008;372:2115-23.
-
(2008)
Lancet
, vol.372
, pp. 2115-2123
-
-
Ho, T.W.1
Ferrari, M.D.2
Dodick, D.W.3
-
81
-
-
84857047327
-
Randomized, controlled study of telcagepant in patients with migraine and coronary artery disease
-
22221076
-
Ho TW, Ho AP, Chaitman BR, et al. Randomized, controlled study of telcagepant in patients with migraine and coronary artery disease. Headache. 2012;52:224-35.
-
(2012)
Headache
, vol.52
, pp. 224-235
-
-
Ho, T.W.1
Ho, A.P.2
Chaitman, B.R.3
-
82
-
-
68149083001
-
Telcagepant, a calcitonin gene-related peptide antagonist for the treatment of migraine
-
1:CAS:528:DC%2BC3cXnt1Khs7c%3D 19579177
-
Tepper SJ, Cleves C. Telcagepant, a calcitonin gene-related peptide antagonist for the treatment of migraine. Curr Opin Investig Drugs. 2009;10:711-20.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 711-720
-
-
Tepper, S.J.1
Cleves, C.2
-
83
-
-
84907987732
-
Randomized controlled trial of the CGRP receptor antagonist telcagepant for migraine prevention
-
1:CAS:528:DC%2BC2cXhsFert7bJ 25107879
-
Ho TW, Connor KM, Zhang Y, et al. Randomized controlled trial of the CGRP receptor antagonist telcagepant for migraine prevention. Neurology. 2014;83:958-66.
-
(2014)
Neurology
, vol.83
, pp. 958-966
-
-
Ho, T.W.1
Connor, K.M.2
Zhang, Y.3
-
84
-
-
84890915149
-
Therapeutic effects and safety of olcegepant and telcagepant for migraine: A meta-analysis
-
4145922 25206386
-
Yao G, Yu T, Han X, Mao X, Li B. Therapeutic effects and safety of olcegepant and telcagepant for migraine: A meta-analysis. Neural Regen Res. 2013;8:938-47.
-
(2013)
Neural Regen Res
, vol.8
, pp. 938-947
-
-
Yao, G.1
Yu, T.2
Han, X.3
Mao, X.4
Li, B.5
-
85
-
-
84871261412
-
Emerging target-based paradigms to prevent and treat migraine
-
Silberstein SD. Emerging target-based paradigms to prevent and treat migraine. Clin Pharm Ther. 2012;93:78-85.
-
(2012)
Clin Pharm Ther
, vol.93
, pp. 78-85
-
-
Silberstein, S.D.1
-
86
-
-
79953220801
-
BI 44370 TA, an oral CGRP antagonist for the treatment of acute migraine attacks: results from a phase II study
-
21172952
-
Diener HC, Barbanti P, Dahlof C, Reuter U, Habeck J, Podhorna J. BI 44370 TA, an oral CGRP antagonist for the treatment of acute migraine attacks: results from a phase II study. Cephalalgia. 2011;31:573-84.
-
(2011)
Cephalalgia
, vol.31
, pp. 573-584
-
-
Diener, H.C.1
Barbanti, P.2
Dahlof, C.3
Reuter, U.4
Habeck, J.5
Podhorna, J.6
-
87
-
-
0033996507
-
Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor
-
1:CAS:528:DC%2BD3cXivVKls7c%3D 10801214
-
Coloma MJ, Lee HJ, Kurihara A, et al. Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor. Pharm Res. 2000;17:266-74.
-
(2000)
Pharm Res
, vol.17
, pp. 266-274
-
-
Coloma, M.J.1
Lee, H.J.2
Kurihara, A.3
-
88
-
-
84978321076
-
Therapeutic monoclonal antibodies for migraine
-
ePub
-
Silberstein SD. Therapeutic monoclonal antibodies for migraine. US Neurol 2015;11 (ePub).
-
(2015)
US Neurol
, pp. 11
-
-
Silberstein, S.D.1
-
89
-
-
84878550146
-
Evolution and emergence of therapeutic monoclonal antibodies: what cardiologists need to know
-
23733968
-
Foltz IN, Karow M, Wasserman SM. Evolution and emergence of therapeutic monoclonal antibodies: what cardiologists need to know. Circulation. 2013;127:2222-30.
-
(2013)
Circulation
, vol.127
, pp. 2222-2230
-
-
Foltz, I.N.1
Karow, M.2
Wasserman, S.M.3
-
90
-
-
17644413164
-
Humanized antibodies and their applications
-
1:CAS:528:DC%2BD2MXjsVegs78%3D 15848069
-
Wu H, Dall'Acqua WF. Humanized antibodies and their applications. Methods. 2005;36:1-2.
-
(2005)
Methods
, vol.36
, pp. 1-2
-
-
Wu, H.1
Dall'Acqua, W.F.2
-
91
-
-
84906262129
-
Safety and efficacy of LY2951742, a monoclonal antibody to calcitonin gene-related peptide, for the prevention of migraine: a phase 2, randomised, double-blind, placebo-controlled study
-
1:CAS:528:DC%2BC2cXhtlCktrjF 25127173
-
Dodick DW, Goadsby PJ, Spierings EL, Scherer JC, Sweeney SP, Grayzel DS. Safety and efficacy of LY2951742, a monoclonal antibody to calcitonin gene-related peptide, for the prevention of migraine: a phase 2, randomised, double-blind, placebo-controlled study. Lancet Neurol. 2014;13:885-92.
-
(2014)
Lancet Neurol
, vol.13
, pp. 885-892
-
-
Dodick, D.W.1
Goadsby, P.J.2
Spierings, E.L.3
Scherer, J.C.4
Sweeney, S.P.5
Grayzel, D.S.6
-
92
-
-
84938209554
-
Randomized, double-blind, placebo-controlled trial of ALD403, an anti-CGRP antibody in the prevention of frequent episodic migraine
-
Valencia
-
Goadsby PJ, Dodick DW, Silberstein SD, Lipton RB, Olesen J, Ashina M, Wilks K, Kudrow D, Kroll R, Kohrman B, Bargar R, Hirman J, and Smith J Randomized, double-blind, placebo-controlled trial of ALD403, an anti-CGRP antibody in the prevention of frequent episodic migraine. In: 17th Congress of the International Headache Society, Valencia, 2015.
-
(2015)
17th Congress of the International Headache Society
-
-
Goadsby, P.J.1
Dodick, D.W.2
Silberstein, S.D.3
Lipton, R.B.4
Olesen, J.5
Ashina, M.6
Wilks, K.7
Kudrow, D.8
Kroll, R.9
Kohrman, B.10
Bargar, R.11
Hirman, J.12
Smith, J.13
-
93
-
-
84907964596
-
Safety and efficacy of ALD403, an antibody to calcitonin gene-related peptide, for the prevention of frequent episodic migraine: a randomised, double-blind, placebo-controlled, exploratory phase 2 trial
-
1:CAS:528:DC%2BC2cXhslagsb%2FK 25297013
-
Dodick DW, Goadsby PJ, Silberstein SD, et al. Safety and efficacy of ALD403, an antibody to calcitonin gene-related peptide, for the prevention of frequent episodic migraine: a randomised, double-blind, placebo-controlled, exploratory phase 2 trial. Lancet Neurol. 2014;13:1100-7.
-
(2014)
Lancet Neurol
, vol.13
, pp. 1100-1107
-
-
Dodick, D.W.1
Goadsby, P.J.2
Silberstein, S.D.3
-
94
-
-
84938215437
-
A multicenter, randomized, double-blind, double-dummy, placebo-controlled, multi-dose study comparing the efficacy and safety of subcutaneous TEV-48125 with placebo for the preventive treatment of chronic migraine
-
Valencia
-
Bigal ME, Edvinsson L, Rapoport A, Lipton R, Spierings E, Diener HC, Ma M, Hudson D, and Silberstein S A multicenter, randomized, double-blind, double-dummy, placebo-controlled, multi-dose study comparing the efficacy and safety of subcutaneous TEV-48125 with placebo for the preventive treatment of chronic migraine. In: 17th Congress of the International Headache Society, Valencia, 2015.
-
(2015)
17th Congress of the International Headache Society
-
-
Bigal, M.E.1
Edvinsson, L.2
Rapoport, A.3
Lipton, R.4
Spierings, E.5
Diener, H.C.6
Ma, M.7
Hudson, D.8
Silberstein, S.9
-
95
-
-
84938204470
-
Results of a randomized, double-blind, placebo-controlled, phase 2 study to evaluate the efficacy and safety of AMG 334 for the prevention of episodic migraine
-
Valencia
-
Lenz R, Silberstein S, Dodick D, Reuter U, Ashina M, Saper J, Cady R, Chon Y, Dietrich J, and Sun H Results of a randomized, double-blind, placebo-controlled, phase 2 study to evaluate the efficacy and safety of AMG 334 for the prevention of episodic migraine. In: 17th Congress of the International Headache Society, Valencia, 2015.
-
(2015)
17th Congress of the International Headache Society
-
-
Lenz, R.1
Silberstein, S.2
Dodick, D.3
Reuter, U.4
Ashina, M.5
Saper, J.6
Cady, R.7
Chon, Y.8
Dietrich, J.9
Sun, H.10
-
96
-
-
58649102662
-
Migraine in the triptan era: lessons from epidemiology, pathophysiology, and clinical science
-
19161562
-
Bigal ME, Ferrari M, Silberstein SD, Lipton RB, Goadsby PJ. Migraine in the triptan era: lessons from epidemiology, pathophysiology, and clinical science. Headache. 2009;49(Suppl 1):S21-33.
-
(2009)
Headache
, vol.49
, pp. S21-S33
-
-
Bigal, M.E.1
Ferrari, M.2
Silberstein, S.D.3
Lipton, R.B.4
Goadsby, P.J.5
-
97
-
-
84903783970
-
Evaluation of cardiovascular parameters in cynomolgus monkeys following IV administration of LBR-101, a monoclonal antibody against calcitonin gene-related peptide
-
4171022 24866108
-
Walter S, Alibhoy A, Escandon R, Bigal ME. Evaluation of cardiovascular parameters in cynomolgus monkeys following IV administration of LBR-101, a monoclonal antibody against calcitonin gene-related peptide. MAbs. 2014;6:871-8.
-
(2014)
MAbs
, vol.6
, pp. 871-878
-
-
Walter, S.1
Alibhoy, A.2
Escandon, R.3
Bigal, M.E.4
-
98
-
-
84908158935
-
Cardiovascular and hemodynamic parameters in women following prolonged CGRP inhibition using LBR-101, a monoclonal antibody against CGRP
-
24662322
-
Bigal ME, Walter S, Bronson M, Alibhoy A, Escandon R. Cardiovascular and hemodynamic parameters in women following prolonged CGRP inhibition using LBR-101, a monoclonal antibody against CGRP. Cephalalgia. 2014;34(12):968-76.
-
(2014)
Cephalalgia
, vol.34
, Issue.12
, pp. 968-976
-
-
Bigal, M.E.1
Walter, S.2
Bronson, M.3
Alibhoy, A.4
Escandon, R.5
-
99
-
-
56749176453
-
CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat
-
1:CAS:528:DC%2BD1cXhsVWhu7rM 2597266 18776916
-
Zeller J, Poulsen KT, Sutton JE, et al. CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat. Br J Pharmacol. 2008;155:1093-103.
-
(2008)
Br J Pharmacol
, vol.155
, pp. 1093-1103
-
-
Zeller, J.1
Poulsen, K.T.2
Sutton, J.E.3
-
100
-
-
84901046526
-
Safety and tolerability of LBR-101, a humanized monoclonal antibody that blocks the binding of CGRP to its receptor: results of the Phase 1 program
-
24366980
-
Bigal ME, Escandon R, Bronson M, et al. Safety and tolerability of LBR-101, a humanized monoclonal antibody that blocks the binding of CGRP to its receptor: results of the Phase 1 program. Cephalalgia. 2013;34:483-92.
-
(2013)
Cephalalgia
, vol.34
, pp. 483-492
-
-
Bigal, M.E.1
Escandon, R.2
Bronson, M.3
-
101
-
-
0028844398
-
Clinical perspectives of calcitonin gene related peptide pharmacology
-
1:CAS:528:DyaK2MXoslCjsLw%3D 8846403
-
Feuerstein G, Willette R, Aiyar N. Clinical perspectives of calcitonin gene related peptide pharmacology. Can J Physiol Pharmacol. 1995;73:1070-4.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 1070-1074
-
-
Feuerstein, G.1
Willette, R.2
Aiyar, N.3
-
102
-
-
77949716986
-
CSF levels and binding pattern of novel CGRP receptor antagonists in rhesus monkey and human central nervous system: toward the development of a PET tracer
-
Sur C, Hargreaves R, Bell I, et al. CSF levels and binding pattern of novel CGRP receptor antagonists in rhesus monkey and human central nervous system: toward the development of a PET tracer. Cephalalgia. 2009;29:136-7.
-
(2009)
Cephalalgia
, vol.29
, pp. 136-137
-
-
Sur, C.1
Hargreaves, R.2
Bell, I.3
-
103
-
-
84886024087
-
In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C]MK-4232
-
1:CAS:528:DC%2BC3sXhslSqsLrK 23975906
-
Hostetler ED, Joshi AD, Sanabria-Bohorquez S, et al. In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C]MK-4232. J Pharmacol Exp Ther. 2013;347:478-86.
-
(2013)
J Pharmacol Exp Ther
, vol.347
, pp. 478-486
-
-
Hostetler, E.D.1
Joshi, A.D.2
Sanabria-Bohorquez, S.3
-
104
-
-
84886606629
-
PET imaging in healthy subjects and migraineurs suggests CGRP receptor antagonists do not have to act centrally to achieve clinical efficacy
-
Abstract
-
Vermeersch SG, deHoon J, deSaint-Hubert B, et al. PET imaging in healthy subjects and migraineurs suggests CGRP receptor antagonists do not have to act centrally to achieve clinical efficacy. J Headache and Pain. 2013;14:224 (Abstract).
-
(2013)
J Headache and Pain
, vol.14
, pp. 224
-
-
Vermeersch, S.G.1
DeHoon, J.2
DeSaint-Hubert, B.3
-
105
-
-
84937517146
-
CGRP receptor antagonists and antibodies against CGRP and its receptor in migraine treatment
-
25731075 [Epub ahead of print]
-
Edvinsson L. CGRP receptor antagonists and antibodies against CGRP and its receptor in migraine treatment. Br J Clin Pharmacol. doi: 10.1111/bcp.12618 [Epub ahead of print]
-
(2015)
Br J Clin Pharmacol
-
-
Edvinsson, L.1
-
106
-
-
0027175057
-
Inhibition by sumatriptan of central trigeminal neurones only after blood-brain barrier disruption
-
1:CAS:528:DyaK3sXltlWnsbw%3D 2175651 8395298
-
Kaube H, Hoskin KL, Goadsby PJ. Inhibition by sumatriptan of central trigeminal neurones only after blood-brain barrier disruption. Br J Pharmacol. 1993;109:788-92.
-
(1993)
Br J Pharmacol
, vol.109
, pp. 788-792
-
-
Kaube, H.1
Hoskin, K.L.2
Goadsby, P.J.3
-
107
-
-
2942615488
-
Cortical spreading depression activates and upregulates MMP-9
-
1:CAS:528:DC%2BD2cXktlCltrY%3D 406541 15146242
-
Gursoy-Ozdemir Y, Qiu J, Matsuoka N, et al. Cortical spreading depression activates and upregulates MMP-9. J Clin Invest. 2004;113:1447-55.
-
(2004)
J Clin Invest
, vol.113
, pp. 1447-1455
-
-
Gursoy-Ozdemir, Y.1
Qiu, J.2
Matsuoka, N.3
-
108
-
-
77954394347
-
Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura
-
1:CAS:528:DC%2BC3cXptFWgs78%3D 2907647 20592202
-
Zhang X, Levy D, Noseda R, Kainz V, Jakubowski M, Burstein R. Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura. J Neurosci. 2010;30:8807-14.
-
(2010)
J Neurosci
, vol.30
, pp. 8807-8814
-
-
Zhang, X.1
Levy, D.2
Noseda, R.3
Kainz, V.4
Jakubowski, M.5
Burstein, R.6
-
109
-
-
79955395563
-
Activation of central trigeminovascular neurons by cortical spreading depression
-
3174689 21416489
-
Zhang X, Levy D, Kainz V, Noseda R, Jakubowski M, Burstein R. Activation of central trigeminovascular neurons by cortical spreading depression. Ann Neurol. 2011;69:855-65.
-
(2011)
Ann Neurol
, vol.69
, pp. 855-865
-
-
Zhang, X.1
Levy, D.2
Kainz, V.3
Noseda, R.4
Jakubowski, M.5
Burstein, R.6
-
110
-
-
84869212309
-
Critical role of calcitonin gene-related peptide receptors in cortical spreading depression
-
1:CAS:528:DC%2BC38Xhsl2itr3P 3503217 23112192
-
Tozzi A, de Iure A, Di Filippo M, et al. Critical role of calcitonin gene-related peptide receptors in cortical spreading depression. Proc Natl Acad Sci USA. 2012;109:18985-90.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 18985-18990
-
-
Tozzi, A.1
De Iure, A.2
Di Filippo, M.3
-
111
-
-
0027217503
-
Cortical spreading depression does not result in the release of calcitonin gene-related peptide into the external jugular vein of the cat: relevance to human migraine
-
1:STN:280:DyaK3szmsV2lsw%3D%3D 8395344
-
Piper RD, Edvinsson L, Ekman R, Lambert GA. Cortical spreading depression does not result in the release of calcitonin gene-related peptide into the external jugular vein of the cat: relevance to human migraine. Cephalalgia. 1993;13:180-3.
-
(1993)
Cephalalgia
, vol.13
, pp. 180-183
-
-
Piper, R.D.1
Edvinsson, L.2
Ekman, R.3
Lambert, G.A.4
-
112
-
-
77950542561
-
Triptan-induced latent sensitization: a possible basis for medication overuse headache
-
De FM, Ossipov MH, Wang R, et al. Triptan-induced latent sensitization: a possible basis for medication overuse headache. Ann Neurol. 2010;67:325-37.
-
(2010)
Ann Neurol
, vol.67
, pp. 325-337
-
-
De, F.M.1
Ossipov, M.H.2
Wang, R.3
-
113
-
-
74549214358
-
Opiate-induced persistent pronociceptive trigeminal neural adaptations: potential relevance to opiate-induced medication overuse headache
-
De FM, Porreca F. Opiate-induced persistent pronociceptive trigeminal neural adaptations: potential relevance to opiate-induced medication overuse headache. Cephalalgia. 2009;29:1277-84.
-
(2009)
Cephalalgia
, vol.29
, pp. 1277-1284
-
-
De, F.M.1
Porreca, F.2
-
114
-
-
84864586682
-
Differential effects of calcitonin gene-related peptide receptor blockade by olcegepant on mechanical allodynia induced by ligation of the infraorbital nerve vs the sciatic nerve in the rat
-
1:CAS:528:DC%2BC38XhtFKnurjI 22795918
-
Michot B, Bourgoin S, Viguier F, Hamon M, Kayser V. Differential effects of calcitonin gene-related peptide receptor blockade by olcegepant on mechanical allodynia induced by ligation of the infraorbital nerve vs the sciatic nerve in the rat. Pain. 2012;153:1939-48.
-
(2012)
Pain
, vol.153
, pp. 1939-1948
-
-
Michot, B.1
Bourgoin, S.2
Viguier, F.3
Hamon, M.4
Kayser, V.5
-
115
-
-
0022798865
-
A quantitative assessment of photophobia in migraine and tension headache
-
1:STN:280:DyaL2s%2Fls1Cmuw%3D%3D 3781834
-
Drummond PD. A quantitative assessment of photophobia in migraine and tension headache. Headache. 1986;26:465-9.
-
(1986)
Headache
, vol.26
, pp. 465-469
-
-
Drummond, P.D.1
-
116
-
-
79955628948
-
Advances in understanding the mechanisms of migraine-type photophobia
-
4502959 21467933
-
Noseda R, Burstein R. Advances in understanding the mechanisms of migraine-type photophobia. Curr Opin Neurol. 2011;24:197-202.
-
(2011)
Curr Opin Neurol
, vol.24
, pp. 197-202
-
-
Noseda, R.1
Burstein, R.2
-
117
-
-
75549087792
-
A neural mechanism for exacerbation of headache by light
-
1:CAS:528:DC%2BC3cXjsVejuw%3D%3D 2818758 20062053
-
Noseda R, Kainz V, Jakubowski M, et al. A neural mechanism for exacerbation of headache by light. Nat Neurosci. 2010;13:239-45.
-
(2010)
Nat Neurosci
, vol.13
, pp. 239-245
-
-
Noseda, R.1
Kainz, V.2
Jakubowski, M.3
-
118
-
-
83455179143
-
Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: implications for photophobia
-
3711521 21337474
-
Maleki N, Becerra L, Upadhyay J, Burstein R, Borsook D. Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: implications for photophobia. Hum Brain Mapp. 2012;33:75-88.
-
(2012)
Hum Brain Mapp
, vol.33
, pp. 75-88
-
-
Maleki, N.1
Becerra, L.2
Upadhyay, J.3
Burstein, R.4
Borsook, D.5
|