-
1
-
-
0025743656
-
Sub-populations of smaller diameter trigeminal primary afferent neurons defined by expression of calcitonin gene-related peptide and the cell surface oligosaccharide recognized by monoclonal antibody LA4
-
F.J. Alvarez, H.R. Morris, and J.V. Priestley Sub-populations of smaller diameter trigeminal primary afferent neurons defined by expression of calcitonin gene-related peptide and the cell surface oligosaccharide recognized by monoclonal antibody LA4 J. Neurocytol. 20 1991 716 731
-
(1991)
J. Neurocytol.
, vol.20
, pp. 716-731
-
-
Alvarez, F.J.1
Morris, H.R.2
Priestley, J.V.3
-
2
-
-
84856160711
-
Headache and prolonged dilatation of the middle meningeal artery by PACAP38 in healthy volunteers
-
F.M. Amin, M.S. Asghar, S. Guo, A. Hougaard, A.E. Hansen, H.W. Schytz, R.J. van der Geest, P.J. de Koning, H.B. Larsson, J. Olesen, and M. Ashina Headache and prolonged dilatation of the middle meningeal artery by PACAP38 in healthy volunteers Cephalalgia 32 2012 140 149
-
(2012)
Cephalalgia
, vol.32
, pp. 140-149
-
-
Amin, F.M.1
Asghar, M.S.2
Guo, S.3
Hougaard, A.4
Hansen, A.E.5
Schytz, H.W.6
Van Der Geest, R.J.7
De Koning, P.J.8
Larsson, H.B.9
Olesen, J.10
Ashina, M.11
-
3
-
-
84876493346
-
Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: A cross-sectional study
-
F.M. Amin, M.S. Asghar, A. Hougaard, A.E. Hansen, V.A. Larsen, P.J. de Koning, H.B. Larsson, J. Olesen, and M. Ashina Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: a cross-sectional study Lancet Neurol. 12 2013 454 461
-
(2013)
Lancet Neurol.
, vol.12
, pp. 454-461
-
-
Amin, F.M.1
Asghar, M.S.2
Hougaard, A.3
Hansen, A.E.4
Larsen, V.A.5
De Koning, P.J.6
Larsson, H.B.7
Olesen, J.8
Ashina, M.9
-
4
-
-
67649612741
-
Therapeutic potential of novel glutamate receptor antagonists in migraine
-
A.P. Andreou, and P.J. Goadsby Therapeutic potential of novel glutamate receptor antagonists in migraine Expert Opin. Investig. Drugs 18 2009 789 803
-
(2009)
Expert Opin. Investig. Drugs
, vol.18
, pp. 789-803
-
-
Andreou, A.P.1
Goadsby, P.J.2
-
5
-
-
0015819079
-
Vascular permeability to fluorescent protein tracer in trigeminal nerve and gasserian ganglion
-
B. Arvidsson, K. Kristensson, and Y. Olsson Vascular permeability to fluorescent protein tracer in trigeminal nerve and gasserian ganglion Acta Neuropathol. 26 1973 199 205
-
(1973)
Acta Neuropathol.
, vol.26
, pp. 199-205
-
-
Arvidsson, B.1
Kristensson, K.2
Olsson, Y.3
-
6
-
-
77953425030
-
Discovery of MK-3207: A highly potent, orally bioavailable CGRP receptor antagonist
-
I.M. Bell, S.N. Gallicchio, M.R. Wood, A.G. Quigley, C.A. Stump, C.B. Zartman, J.F. Fay, C.C. Li, J.J. Lynch, E.L. Moore, S.D. Mosser, T. Prueksaritanont, C.P. Regan, S. Roller, C.A. Salvatore, S.A. Kane, J.P. Vacca, and H.G. Selnick Discovery of MK-3207: a highly potent, orally bioavailable CGRP receptor antagonist ACS Med. Chem. Lett. 1 2010 24 29
-
(2010)
ACS Med. Chem. Lett.
, vol.1
, pp. 24-29
-
-
Bell, I.M.1
Gallicchio, S.N.2
Wood, M.R.3
Quigley, A.G.4
Stump, C.A.5
Zartman, C.B.6
Fay, J.F.7
Li, C.C.8
Lynch, J.J.9
Moore, E.L.10
Mosser, S.D.11
Prueksaritanont, T.12
Regan, C.P.13
Roller, S.14
Salvatore, C.A.15
Kane, S.A.16
Vacca, J.P.17
Selnick, H.G.18
-
7
-
-
33645101201
-
Salivary levels of CGRP and VIP in rhinosinusitis and migraine patients
-
J.L. Bellamy, R.K. Cady, and P.L. Durham Salivary levels of CGRP and VIP in rhinosinusitis and migraine patients Headache 46 2006 24 33
-
(2006)
Headache
, vol.46
, pp. 24-33
-
-
Bellamy, J.L.1
Cady, R.K.2
Durham, P.L.3
-
8
-
-
84890849030
-
MRNA distribution of CGRP and its receptor components in the trigeminovascular system and other pain related structures in rat brain, and effect of intracerebroventricular administration of CGRP on Fos expression in the TNC
-
D.K. Bhatt, S. Gupta, K.B. Ploug, I. Jansen-Olesen, and J. Olesen mRNA distribution of CGRP and its receptor components in the trigeminovascular system and other pain related structures in rat brain, and effect of intracerebroventricular administration of CGRP on Fos expression in the TNC Neurosci. Lett. 559 2014 99 104
-
(2014)
Neurosci. Lett.
, vol.559
, pp. 99-104
-
-
Bhatt, D.K.1
Gupta, S.2
Ploug, K.B.3
Jansen-Olesen, I.4
Olesen, J.5
-
9
-
-
84884151958
-
Calcitonin gene-related peptide (CGRP) and migraine current understanding and state of development
-
M.E. Bigal, S. Walter, and A.M. Rapoport Calcitonin gene-related peptide (CGRP) and migraine current understanding and state of development Headache 53 2013 1230 1244
-
(2013)
Headache
, vol.53
, pp. 1230-1244
-
-
Bigal, M.E.1
Walter, S.2
Rapoport, A.M.3
-
10
-
-
33646928617
-
Functional imaging of the trigeminal system: Applications to migraine pathophysiology
-
D. Borsook, R. Burstein, E. Moulton, and L. Becerra Functional imaging of the trigeminal system: applications to migraine pathophysiology Headache 46 Suppl. 1 2006 S32 S38
-
(2006)
Headache
, vol.46
, pp. S32-S38
-
-
Borsook, D.1
Burstein, R.2
Moulton, E.3
Becerra, L.4
-
11
-
-
84888324384
-
Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine
-
E. Cernuda-Morollon, D. Larrosa, C. Ramon, J. Vega, P. Martinez-Camblor, and J. Pascual Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine Neurology 81 14:1191-1196 2013
-
(2013)
Neurology 81 14:1191-1196
-
-
Cernuda-Morollon, E.1
Larrosa, D.2
Ramon, C.3
Vega, J.4
Martinez-Camblor, P.5
Pascual, J.6
-
12
-
-
77956233522
-
Characterization of the CGRP receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries
-
K. Chan, L. Edvinsson, S. Eftekhari, P.O. Kimblad, S. Kane, J. Lynch, R. Hargreaves, R. de Vries, I. Garrelds, A. van den Bogaerdt, J. Danser, and A. Maassenvandenbrink Characterization of the CGRP receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries J. Pharmacol. Exp. Ther. 334:746-752 2010
-
(2010)
J. Pharmacol. Exp. Ther. 334:746-752
-
-
Chan, K.1
Edvinsson, L.2
Eftekhari, S.3
Kimblad, P.O.4
Kane, S.5
Lynch, J.6
Hargreaves, R.7
De Vries, R.8
Garrelds, I.9
Van Den Bogaerdt, A.10
Danser, J.11
Maassenvandenbrink, A.12
-
13
-
-
84877708795
-
Migraine: A brain state
-
A. Charles Migraine: a brain state Curr. Opin. Neurol. 26 2013 235 239
-
(2013)
Curr. Opin. Neurol.
, vol.26
, pp. 235-239
-
-
Charles, A.1
-
14
-
-
84871279046
-
Trigeminal satellite cells modulate neuronal responses to triptans: Relevance for migraine therapy
-
A. de Corato, A. Capuano, D. Curro, G. Tringali, P. Navarra, and C. Dello Russo Trigeminal satellite cells modulate neuronal responses to triptans: relevance for migraine therapy Neuron Glia Biol. 7 2011 109 116
-
(2011)
Neuron Glia Biol.
, vol.7
, pp. 109-116
-
-
De Corato, A.1
Capuano, A.2
Curro, D.3
Tringali, G.4
Navarra, P.5
Dello Russo, C.6
-
15
-
-
79751470430
-
Increase in CGRP- and nNOS-immunoreactive neurons in the rat trigeminal ganglion after infusion of an NO donor
-
A. Dieterle, M.J. Fischer, A.S. Link, W.L. Neuhuber, and K. Messlinger Increase in CGRP- and nNOS-immunoreactive neurons in the rat trigeminal ganglion after infusion of an NO donor Cephalalgia 31 2011 31 42
-
(2011)
Cephalalgia
, vol.31
, pp. 31-42
-
-
Dieterle, A.1
Fischer, M.J.2
Link, A.S.3
Neuhuber, W.L.4
Messlinger, K.5
-
16
-
-
84875721109
-
Antibody drugs set to revive flagging migraine target
-
E. Dolgin Antibody drugs set to revive flagging migraine target Nat. Rev. Drug Discov. 12 2013 249 250
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 249-250
-
-
Dolgin, E.1
-
17
-
-
77953273344
-
Calcitonin gene-related peptide (CGRP) receptor antagonists in the treatment of migraine
-
P.L. Durham, and C.V. Vause Calcitonin gene-related peptide (CGRP) receptor antagonists in the treatment of migraine CNS Drugs 24 2010 539 548
-
(2010)
CNS Drugs
, vol.24
, pp. 539-548
-
-
Durham, P.L.1
Vause, C.V.2
-
19
-
-
79952113515
-
Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries
-
L. Edvinsson, K.Y. Chan, S. Eftekhari, E. Nilsson, R. de Vries, H. Saveland, C.M. Dirven, A.H. Danser, and A. MaassenVanDenBrink Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries Cephalalgia 30 2010 1233 1240
-
(2010)
Cephalalgia
, vol.30
, pp. 1233-1240
-
-
Edvinsson, L.1
Chan, K.Y.2
Eftekhari, S.3
Nilsson, E.4
De Vries, R.5
Saveland, H.6
Dirven, C.M.7
Danser, A.H.8
Maassenvandenbrink, A.9
-
20
-
-
0035341124
-
Origin and Co-localization of nitric oxide synthase, CGRP, PACAP, and VIP in the cerebral circulation of the rat
-
L. Edvinsson, T. Elsas, N. Suzuki, T. Shimizu, and T.J. Lee Origin and Co-localization of nitric oxide synthase, CGRP, PACAP, and VIP in the cerebral circulation of the rat Microsc. Res. Tech. 53 2001 221 228
-
(2001)
Microsc. Res. Tech.
, vol.53
, pp. 221-228
-
-
Edvinsson, L.1
Elsas, T.2
Suzuki, N.3
Shimizu, T.4
Lee, T.J.5
-
21
-
-
0025116298
-
Extracerebral manifestations in migraine. A peptidergic involvement?
-
L. Edvinsson, and P.J. Goadsby Extracerebral manifestations in migraine. A peptidergic involvement? J. Intern. Med. 228 1990 299 304
-
(1990)
J. Intern. Med.
, vol.228
, pp. 299-304
-
-
Edvinsson, L.1
Goadsby, P.J.2
-
22
-
-
77956074035
-
New drugs in migraine treatment and prophylaxis: Telcagepant and topiramate
-
L. Edvinsson, and M. Linde New drugs in migraine treatment and prophylaxis: telcagepant and topiramate Lancet 376 2010 645 655
-
(2010)
Lancet
, vol.376
, pp. 645-655
-
-
Edvinsson, L.1
Linde, M.2
-
23
-
-
33847671313
-
Inhibitory effect of BIBN4096BS, CGRP(8-37), a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery
-
L. Edvinsson, E. Nilsson, and I. Jansen-Olesen Inhibitory effect of BIBN4096BS, CGRP(8-37), a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery Br. J. Pharmacol. 150 2007 633 640
-
(2007)
Br. J. Pharmacol.
, vol.150
, pp. 633-640
-
-
Edvinsson, L.1
Nilsson, E.2
Jansen-Olesen, I.3
-
24
-
-
56549109172
-
The blood-brain barrier in migraine treatment
-
L.1 Edvinsson, and P. Tfelt-Hansen The blood-brain barrier in migraine treatment Cephalalgia 12 2008 1245 1258
-
(2008)
Cephalalgia
, vol.12
, pp. 1245-1258
-
-
Edvinsson, L.1
Tfelt-Hansen, P.2
-
25
-
-
78649940547
-
Possible sites of action of the new calcitonin gene-related peptide receptor antagonists
-
S. Eftekhari, and L. Edvinsson Possible sites of action of the new calcitonin gene-related peptide receptor antagonists Ther. Adv. Neurol. Disord. 3 2010 369 378
-
(2010)
Ther. Adv. Neurol. Disord.
, vol.3
, pp. 369-378
-
-
Eftekhari, S.1
Edvinsson, L.2
-
26
-
-
84923353860
-
Localization of CGRP receptor components, CGRP and receptor binding sites in rhesus brainstem: A detailed study using in situ hybridization and autoradiography
-
(Supplement)
-
S. Eftekhari, R. Gaspar, R. Roberts, S. Villarreal, T. Chen, Z. Zeng, L. Edvinsson, and C. Salvatore Localization of CGRP receptor components, CGRP and receptor binding sites in rhesus brainstem: a detailed study using in situ hybridization and autoradiography Cephalalgia 2013 2013 33 (Supplement)
-
(2013)
Cephalalgia
, vol.2013
, pp. 33
-
-
Eftekhari, S.1
Gaspar, R.2
Roberts, R.3
Villarreal, S.4
Chen, T.5
Zeng, Z.6
Edvinsson, L.7
Salvatore, C.8
-
27
-
-
77954620156
-
Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion
-
S. Eftekhari, C.A. Salvatore, A. Calamari, S.A. Kane, J. Tajti, and L. Edvinsson Differential distribution of calcitonin gene-related peptide and its receptor components in the human trigeminal ganglion Neuroscience 169 2010 683 696
-
(2010)
Neuroscience
, vol.169
, pp. 683-696
-
-
Eftekhari, S.1
Salvatore, C.A.2
Calamari, A.3
Kane, S.A.4
Tajti, J.5
Edvinsson, L.6
-
28
-
-
84892444332
-
Localization of CGRP receptor components, CGRP, and receptor binding sites in human and rhesus cerebellar cortex
-
S. Eftekhari, C.A. Salvatore, R.C. Gaspar, R. Roberts, S. O'Malley, Z. Zeng, and L. Edvinsson Localization of CGRP receptor components, CGRP, and receptor binding sites in human and rhesus cerebellar cortex Cerebellum 12 2013 937 949
-
(2013)
Cerebellum
, vol.12
, pp. 937-949
-
-
Eftekhari, S.1
Salvatore, C.A.2
Gaspar, R.C.3
Roberts, R.4
O'Malley, S.5
Zeng, Z.6
Edvinsson, L.7
-
29
-
-
84887084591
-
Differentiation of nerve fibers storing CGRP and CGRP receptors in the peripheral trigeminovascular system
-
S. Eftekhari, K. Warfvinge, F.W. Blixt, and L. Edvinsson Differentiation of nerve fibers storing CGRP and CGRP receptors in the peripheral trigeminovascular system J. Pain 14 2013 1289 1303
-
(2013)
J. Pain
, vol.14
, pp. 1289-1303
-
-
Eftekhari, S.1
Warfvinge, K.2
Blixt, F.W.3
Edvinsson, L.4
-
30
-
-
33845882288
-
Recent advances in understanding migraine mechanisms, molecules and therapeutics
-
P.J. Goadsby Recent advances in understanding migraine mechanisms, molecules and therapeutics Trends Mol. Med. 13 2007 39 44
-
(2007)
Trends Mol. Med.
, vol.13
, pp. 39-44
-
-
Goadsby, P.J.1
-
32
-
-
0027509161
-
The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats
-
P.J. Goadsby, and L. Edvinsson The trigeminovascular system and migraine: studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats Ann. Neurol. 33 1993 48 56
-
(1993)
Ann. Neurol.
, vol.33
, pp. 48-56
-
-
Goadsby, P.J.1
Edvinsson, L.2
-
33
-
-
0023874663
-
Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system
-
P.J. Goadsby, L. Edvinsson, and R. Ekman Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system Ann. Neurol. 23 1988 193 196
-
(1988)
Ann. Neurol.
, vol.23
, pp. 193-196
-
-
Goadsby, P.J.1
Edvinsson, L.2
Ekman, R.3
-
34
-
-
0025143541
-
Vasoactive peptide release in the extracerebral circulation of humans during migraine headache
-
P.J. Goadsby, L. Edvinsson, and R. Ekman Vasoactive peptide release in the extracerebral circulation of humans during migraine headache Ann. Neurol. 28 1990 183 187
-
(1990)
Ann. Neurol.
, vol.28
, pp. 183-187
-
-
Goadsby, P.J.1
Edvinsson, L.2
Ekman, R.3
-
35
-
-
2942615488
-
Cortical spreading depression activates and upregulates MMP-9
-
Y. Gursoy-Ozdemir, J. Qiu, N. Matsuoka, H. Bolay, D. Bermpohl, and H.e.t. Jin Cortical spreading depression activates and upregulates MMP-9 J. Clin. Invest. 113 2004 1447 1455
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1447-1455
-
-
Gursoy-Ozdemir, Y.1
Qiu, J.2
Matsuoka, N.3
Bolay, H.4
Bermpohl, D.5
-
36
-
-
78650413846
-
Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura
-
J.M. Hansen, A.W. Hauge, J. Olesen, and M. Ashina Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura Cephalalgia 30 2010 1179 1186
-
(2010)
Cephalalgia
, vol.30
, pp. 1179-1186
-
-
Hansen, J.M.1
Hauge, A.W.2
Olesen, J.3
Ashina, M.4
-
37
-
-
77957922955
-
CGRP and its receptors provide new insights into migraine pathophysiology
-
T.W. Ho, L. Edvinsson, and P.J. Goadsby CGRP and its receptors provide new insights into migraine pathophysiology Nat. Rev. Neurol. 6 2010 573 582
-
(2010)
Nat. Rev. Neurol.
, vol.6
, pp. 573-582
-
-
Ho, T.W.1
Edvinsson, L.2
Goadsby, P.J.3
-
38
-
-
57649233374
-
Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: A randomised, placebo-controlled, parallel-treatment trial
-
T.W. Ho, M.D. Ferrari, D.W. Dodick, V. Galet, J. Kost, X. Fan, H. Leibensperger, S. Froman, C. Assaid, C. Lines, H. Koppen, and P.K. Winner Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial Lancet 372 2008 2115 2123
-
(2008)
Lancet
, vol.372
, pp. 2115-2123
-
-
Ho, T.W.1
Ferrari, M.D.2
Dodick, D.W.3
Galet, V.4
Kost, J.5
Fan, X.6
Leibensperger, H.7
Froman, S.8
Assaid, C.9
Lines, C.10
Koppen, H.11
Winner, P.K.12
-
39
-
-
42249087655
-
Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine
-
T.W. Ho, L.K. Mannix, X. Fan, C. Assaid, C. Furtek, C.J. Jones, C.R. Lines, and A.M. Rapoport Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine Neurology 70 2008 1304 1312
-
(2008)
Neurology
, vol.70
, pp. 1304-1312
-
-
Ho, T.W.1
Mannix, L.K.2
Fan, X.3
Assaid, C.4
Furtek, C.5
Jones, C.J.6
Lines, C.R.7
Rapoport, A.M.8
-
40
-
-
84886024087
-
In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C]MK-4232
-
E.D. Hostetler, A.D. Joshi, S. Sanabria-Bohorquez, H. Fan, Z. Zeng, M. Purcell, L. Gantert, K. Riffel, M. Williams, S. O'Malley, P. Miller, H.G. Selnick, S.N. Gallicchio, I.M. Bell, C.A. Salvatore, S.A. Kane, C.C. Li, R.J. Hargreaves, T. de Groot, G. Bormans, A. Van Hecken, I. Derdelinckx, J. de Hoon, T. Reynders, R. Declercq, I. De Lepeleire, W.P. Kennedy, R. Blanchard, E.E. Marcantonio, C. Sur, J.J. Cook, K. Van Laere, and J.L. Evelhoch In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C]MK-4232 J. Pharmacol. Exp. Ther. 347 2013 478 486
-
(2013)
J. Pharmacol. Exp. Ther.
, vol.347
, pp. 478-486
-
-
Hostetler, E.D.1
Joshi, A.D.2
Sanabria-Bohorquez, S.3
Fan, H.4
Zeng, Z.5
Purcell, M.6
Gantert, L.7
Riffel, K.8
Williams, M.9
O'Malley, S.10
Miller, P.11
Selnick, H.G.12
Gallicchio, S.N.13
Bell, I.M.14
Salvatore, C.A.15
Kane, S.A.16
Li, C.C.17
Hargreaves, R.J.18
De Groot, T.19
Bormans, G.20
Van Hecken, A.21
Derdelinckx, I.22
De Hoon, J.23
Reynders, T.24
Declercq, R.25
De Lepeleire, I.26
Kennedy, W.P.27
Blanchard, R.28
Marcantonio, E.E.29
Sur, C.30
Cook, J.J.31
Van Laere, K.32
Evelhoch, J.L.33
more..
-
41
-
-
0035800636
-
5-HT(1B) and 5-HT(1D) receptors in the human trigeminal ganglion: Co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase
-
M. Hou, M. Kanje, J. Longmore, J. Tajti, R. Uddman, and L. Edvinsson 5-HT(1B) and 5-HT(1D) receptors in the human trigeminal ganglion: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase Brain Res. 909 2001 112 120
-
(2001)
Brain Res.
, vol.909
, pp. 112-120
-
-
Hou, M.1
Kanje, M.2
Longmore, J.3
Tajti, J.4
Uddman, R.5
Edvinsson, L.6
-
42
-
-
84893709298
-
Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists
-
P. Joshi, C. Anderson, H. Binch, S. Hadida, S. Yoo, D. Bergeron, C. Decker, E. Terhaar, J. Moore, M. Garcia-Guzman, and A. Termin Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists Bioorg. Med. Chem. Lett. 24 2014 845 849
-
(2014)
Bioorg. Med. Chem. Lett.
, vol.24
, pp. 845-849
-
-
Joshi, P.1
Anderson, C.2
Binch, H.3
Hadida, S.4
Yoo, S.5
Bergeron, D.6
Decker, C.7
Terhaar, E.8
Moore, J.9
Garcia-Guzman, M.10
Termin, A.11
-
43
-
-
0025903460
-
Glutamate-immunoreactivity in the trigeminal and dorsal root ganglia, and intraspinal neurons and fibres in the dorsal horn of the rat
-
M.A. Kai-Kai, and R. Howe Glutamate-immunoreactivity in the trigeminal and dorsal root ganglia, and intraspinal neurons and fibres in the dorsal horn of the rat Histochem. J. 23 1991 171 179
-
(1991)
Histochem. J.
, vol.23
, pp. 171-179
-
-
Kai-Kai, M.A.1
Howe, R.2
-
44
-
-
84888016627
-
CGRP and migraine: Could PACAP play a role too?
-
E.A. Kaiser, and A.F. Russo CGRP and migraine: could PACAP play a role too? Neuropeptides 47 2013 451 461
-
(2013)
Neuropeptides
, vol.47
, pp. 451-461
-
-
Kaiser, E.A.1
Russo, A.F.2
-
45
-
-
0027175057
-
Inhibition by sumatriptan of central trigeminal neurones only after blood-brain barrier disruption
-
H. Kaube, K.L. Hoskin, and P.J. Goadsby Inhibition by sumatriptan of central trigeminal neurones only after blood-brain barrier disruption Br. J. Pharmacol. 109 1993 788 792
-
(1993)
Br. J. Pharmacol.
, vol.109
, pp. 788-792
-
-
Kaube, H.1
Hoskin, K.L.2
Goadsby, P.J.3
-
46
-
-
0029985023
-
Vascular permeability in the peripheral autonomic and somatic nervous systems: Controversial aspects and comparisons with the blood-brain barrier
-
J.A. Kiernan Vascular permeability in the peripheral autonomic and somatic nervous systems: controversial aspects and comparisons with the blood-brain barrier Microsc. Res. Tech. 35 1996 122 136
-
(1996)
Microsc. Res. Tech.
, vol.35
, pp. 122-136
-
-
Kiernan, J.A.1
-
47
-
-
40949083906
-
Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: Differences between peripheral and central CGRP receptor distribution
-
J.K. Lennerz, V. Ruhle, E.P. Ceppa, W.L. Neuhuber, N.W. Bunnett, E.F. Grady, and K. Messlinger Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: differences between peripheral and central CGRP receptor distribution J. Comp. Neurol. 507 2008 1277 1299
-
(2008)
J. Comp. Neurol.
, vol.507
, pp. 1277-1299
-
-
Lennerz, J.K.1
Ruhle, V.2
Ceppa, E.P.3
Neuhuber, W.L.4
Bunnett, N.W.5
Grady, E.F.6
Messlinger, K.7
-
48
-
-
27644461793
-
Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: Implications for the pathophysiology of migraine
-
D. Levy, R. Burstein, and A.M. Strassman Calcitonin gene-related peptide does not excite or sensitize meningeal nociceptors: implications for the pathophysiology of migraine Ann. Neurol. 58 5 2005 698 705
-
(2005)
Ann. Neurol.
, vol.58
, Issue.5
, pp. 698-705
-
-
Levy, D.1
Burstein, R.2
Strassman, A.M.3
-
49
-
-
39149112474
-
Calcitonin gene-related peptide stimulation of nitric oxide synthesis and release from trigeminal ganglion glial cells
-
J. Li, C.V. Vause, and P.L. Durham Calcitonin gene-related peptide stimulation of nitric oxide synthesis and release from trigeminal ganglion glial cells Brain Res. 1196 2008 22 32
-
(2008)
Brain Res.
, vol.1196
, pp. 22-32
-
-
Li, J.1
Vause, C.V.2
Durham, P.L.3
-
50
-
-
68249115581
-
Brainstem and thalamic projections from a craniovascular sensory nervous centre in the rostral cervical spinal dorsal horn of rats
-
Liu Y, Broman J, Zhang M, Edvinsson L 2009. Brainstem and thalamic projections from a craniovascular sensory nervous centre in the rostral cervical spinal dorsal horn of rats. Cephalalgia 29:935-948.
-
(2009)
Cephalalgia
, vol.29
, pp. 935-948
-
-
Liu, Y.1
Broman, J.2
Zhang, M.3
Edvinsson, L.4
-
51
-
-
0022549867
-
Immunoelectron microscopic study of substance P-containing fibers in feline cerebral arteries
-
L.Y. Liu-Chen, T.M. Liszczak, J.C. King, and M.A. Moskowitz Immunoelectron microscopic study of substance P-containing fibers in feline cerebral arteries Brain Res. 369 1986 12 20
-
(1986)
Brain Res.
, vol.369
, pp. 12-20
-
-
Liu-Chen, L.Y.1
Liszczak, T.M.2
King, J.C.3
Moskowitz, M.A.4
-
52
-
-
0035063723
-
An in vivo rat model to study calcitonin gene related peptide release following activation of the trigeminal vascular system
-
V. Limmroth, Z. Katsarava, B. Liedert, H. Guehring, K. Schmitz, H.C. Diener, and M.C. Michel An in vivo rat model to study calcitonin gene related peptide release following activation of the trigeminal vascular system Pain 92 2001 101 106
-
(2001)
Pain
, vol.92
, pp. 101-106
-
-
Limmroth, V.1
Katsarava, Z.2
Liedert, B.3
Guehring, H.4
Schmitz, K.5
Diener, H.C.6
Michel, M.C.7
-
53
-
-
77952473377
-
Glutamatergic fine tuning with ADX-10059: A novel therapeutic approach for migraine?
-
J.C. Marin, and P.J. Goadsby Glutamatergic fine tuning with ADX-10059: a novel therapeutic approach for migraine? Expert Opin. Investig. Drugs 19 2010 555 561
-
(2010)
Expert Opin. Investig. Drugs
, vol.19
, pp. 555-561
-
-
Marin, J.C.1
Goadsby, P.J.2
-
54
-
-
0025742665
-
Neurons with access to the general circulation in the central nervous system of the rat: A retrograde tracing study with fluoro-gold
-
I. Merchenthaler Neurons with access to the general circulation in the central nervous system of the rat: a retrograde tracing study with fluoro-gold Neuroscience 44 1991 655 662
-
(1991)
Neuroscience
, vol.44
, pp. 655-662
-
-
Merchenthaler, I.1
-
55
-
-
0027519980
-
Pituitary adenylate cyclase activating peptide is a sensory neuropeptide: Immunocytochemical and immunochemical evidence
-
K. Moller, Y.Z. Zhang, R. Hakanson, A. Luts, B. Sjolund, R. Uddman, and F. Sundler Pituitary adenylate cyclase activating peptide is a sensory neuropeptide: immunocytochemical and immunochemical evidence Neuroscience 57 1993 725 732
-
(1993)
Neuroscience
, vol.57
, pp. 725-732
-
-
Moller, K.1
Zhang, Y.Z.2
Hakanson, R.3
Luts, A.4
Sjolund, B.5
Uddman, R.6
Sundler, F.7
-
56
-
-
84859726761
-
Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine
-
E.L. Moore, and C.A. Salvatore Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine Br. J. Pharmacol. 166 2012 66 78
-
(2012)
Br. J. Pharmacol.
, vol.166
, pp. 66-78
-
-
Moore, E.L.1
Salvatore, C.A.2
-
57
-
-
12844266029
-
Most peptide-containing sensory neurons lack proteins for exocytotic release and vesicular transport of glutamate
-
J.L. Morris, P. Konig, T. Shimizu, P. Jobling, and I.L. Gibbins Most peptide-containing sensory neurons lack proteins for exocytotic release and vesicular transport of glutamate J. Comp. Neurol. 483 2005 1 16
-
(2005)
J. Comp. Neurol.
, vol.483
, pp. 1-16
-
-
Morris, J.L.1
Konig, P.2
Shimizu, T.3
Jobling, P.4
Gibbins, I.L.5
-
59
-
-
0025285858
-
Origins and distribution of cerebrovascular nerve fibers showing calcitonin gene-related peptide-like immunoreactivity in the major cerebral artery of the dog
-
K. Nozaki, Y. Uemura, S. Okamoto, H. Kikuchi, and N. Mizuno Origins and distribution of cerebrovascular nerve fibers showing calcitonin gene-related peptide-like immunoreactivity in the major cerebral artery of the dog J. Comp. Neurol. 297 1990 219 226
-
(1990)
J. Comp. Neurol.
, vol.297
, pp. 219-226
-
-
Nozaki, K.1
Uemura, Y.2
Okamoto, S.3
Kikuchi, H.4
Mizuno, N.5
-
60
-
-
1542346238
-
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine
-
J. Olesen, H.C. Diener, I.W. Husstedt, P.J. Goadsby, D. Hall, U. Meier, S. Pollentier, and L.M. Lesko Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine N. Engl. J. Med. 350 2004 1104 1110
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1104-1110
-
-
Olesen, J.1
Diener, H.C.2
Husstedt, I.W.3
Goadsby, P.J.4
Hall, D.5
Meier, U.6
Pollentier, S.7
Lesko, L.M.8
-
61
-
-
0030983609
-
Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide
-
A. Ottosson, and L. Edvinsson Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide Cephalalgia 17 1997 166 174
-
(1997)
Cephalalgia
, vol.17
, pp. 166-174
-
-
Ottosson, A.1
Edvinsson, L.2
-
62
-
-
11844274555
-
Correlation between lipophilicity and triptan outcomes
-
J. Pascual, and P. Munoz Correlation between lipophilicity and triptan outcomes Headache 45 2005 3 6
-
(2005)
Headache
, vol.45
, pp. 3-6
-
-
Pascual, J.1
Munoz, P.2
-
63
-
-
84857084559
-
Calcitonin gene-related peptide in migraine: Intersection of peripheral inflammation and central modulation
-
A.C. Raddant, and A.F. Russo Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation Expert Rev. Mol. Med. 13 2011 e36
-
(2011)
Expert Rev. Mol. Med.
, vol.13
, pp. e36
-
-
Raddant, A.C.1
Russo, A.F.2
-
64
-
-
0028791935
-
Cerebrospinal fluid analyses in migraine patients and controls
-
J.F. Rothrock, K.R. Mar, T.L. Yaksh, A. Golbeck, and A.C. Moore Cerebrospinal fluid analyses in migraine patients and controls Cephalalgia 15 1995 489 493
-
(1995)
Cephalalgia
, vol.15
, pp. 489-493
-
-
Rothrock, J.F.1
Mar, K.R.2
Yaksh, T.L.3
Golbeck, A.4
Moore, A.C.5
-
65
-
-
80053530076
-
CGRP receptor antagonists: Toward a novel migraine therapy
-
C.A. Salvatore, and S.A. Kane CGRP receptor antagonists: toward a novel migraine therapy Curr. Pharm. Biotechnol. 12 2011 1671 1680
-
(2011)
Curr. Pharm. Biotechnol.
, vol.12
, pp. 1671-1680
-
-
Salvatore, C.A.1
Kane, S.A.2
-
66
-
-
77949687406
-
Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist
-
C.A. Salvatore, E.L. Moore, A. Calamari, J.J. Cook, M.S. Michener, S. O'Malley, P.J. Miller, C. Sur, D.L. Williams Jr., Z. Zeng, A. Danziger, J.J. Lynch, C.P. Regan, J.F. Fay, Y.S. Tang, C.C. Li, N.T. Pudvah, R.B. White, I.M. Bell, S.N. Gallicchio, S.L. Graham, H.G. Selnick, J.P. Vacca, and S.A. Kane Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist J. Pharmacol. Exp. Ther. 333 2010 152 160
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.333
, pp. 152-160
-
-
Salvatore, C.A.1
Moore, E.L.2
Calamari, A.3
Cook, J.J.4
Michener, M.S.5
O'Malley, S.6
Miller, P.J.7
Sur, C.8
Williams, Jr.D.L.9
Zeng, Z.10
Danziger, A.11
Lynch, J.J.12
Regan, C.P.13
Fay, J.F.14
Tang, Y.S.15
Li, C.C.16
Pudvah, N.T.17
White, R.B.18
Bell, I.M.19
Gallicchio, S.N.20
Graham, S.L.21
Selnick, H.G.22
Vacca, J.P.23
Kane, S.A.24
more..
-
67
-
-
58849084087
-
PACAP38 induces migraine-like attacks in patients with migraine without aura
-
H.W. Schytz, S. Birk, T. Wienecke, C. Kruuse, J. Olesen, and M. Ashina PACAP38 induces migraine-like attacks in patients with migraine without aura Brain 132 2009 16 25
-
(2009)
Brain
, vol.132
, pp. 16-25
-
-
Schytz, H.W.1
Birk, S.2
Wienecke, T.3
Kruuse, C.4
Olesen, J.5
Ashina, M.6
-
68
-
-
84900200516
-
Changes in calcitonin gene-related peptide (CGRP) receptor component and nitric oxide receptor (sGC) immunoreactivity in rat trigeminal ganglion following glyceroltrinitrate pretreatment
-
K. Seiler, J.I. Nusser, J.K. Lennerz, W.L. Neuhuber, and K. Messlinger Changes in calcitonin gene-related peptide (CGRP) receptor component and nitric oxide receptor (sGC) immunoreactivity in rat trigeminal ganglion following glyceroltrinitrate pretreatment J. Headache Pain 14 2013 74
-
(2013)
J. Headache Pain
, vol.14
, pp. 74
-
-
Seiler, K.1
Nusser, J.I.2
Lennerz, J.K.3
Neuhuber, W.L.4
Messlinger, K.5
-
69
-
-
71049155874
-
Migraine pathogenesis and state of pharmacological treatment options
-
T. Sprenger, and P.J. Goadsby Migraine pathogenesis and state of pharmacological treatment options BMC Med. 7 2009 71
-
(2009)
BMC Med.
, vol.7
, pp. 71
-
-
Sprenger, T.1
Goadsby, P.J.2
-
70
-
-
0034988854
-
Neuropeptide localization in the "migraine generator" region of the human brainstem
-
J. Tajti, R. Uddman, and L. Edvinsson Neuropeptide localization in the "migraine generator" region of the human brainstem Cephalalgia 21 2001 96 101
-
(2001)
Cephalalgia
, vol.21
, pp. 96-101
-
-
Tajti, J.1
Uddman, R.2
Edvinsson, L.3
-
71
-
-
0033036503
-
Messenger molecules and receptor mRNA in the human trigeminal ganglion
-
J. Tajti, R. Uddman, S. Moller, F. Sundler, and L. Edvinsson Messenger molecules and receptor mRNA in the human trigeminal ganglion J. Auton. Nerv. Syst. 76 1999 176 183
-
(1999)
J. Auton. Nerv. Syst.
, vol.76
, pp. 176-183
-
-
Tajti, J.1
Uddman, R.2
Moller, S.3
Sundler, F.4
Edvinsson, L.5
-
72
-
-
0024381539
-
Satellite cells as blood-ganglion cell barrier in autonomic ganglia
-
M.P. Ten Tusscher, J. Klooster, and G.F. Vrensen Satellite cells as blood-ganglion cell barrier in autonomic ganglia Brain Res. 490 1989 95 102
-
(1989)
Brain Res.
, vol.490
, pp. 95-102
-
-
Ten Tusscher, M.P.1
Klooster, J.2
Vrensen, G.F.3
-
73
-
-
0023904914
-
Cerebral arterial innervation by nerve fibers containing calcitonin gene-related peptide (CGRP): I. Distribution and origin of CGRP perivascular innervation in the rat
-
S.H. Tsai, J.M. Tew, J.H. McLean, and M.T. Shipley Cerebral arterial innervation by nerve fibers containing calcitonin gene-related peptide (CGRP): I. Distribution and origin of CGRP perivascular innervation in the rat J. Comp. Neurol. 271 1988 435 444
-
(1988)
J. Comp. Neurol.
, vol.271
, pp. 435-444
-
-
Tsai, S.H.1
Tew, J.M.2
McLean, J.H.3
Shipley, M.T.4
-
74
-
-
84884186372
-
Alterations in PACAP-38-like immunoreactivity in the plasma during ictal and interictal periods of migraine patients
-
B. Tuka, Z. Helyes, A. Markovics, T. Bagoly, J. Szolcsanyi, N. Szabo, E. Toth, Z.T. Kincses, L. Vecsei, and J. Tajti Alterations in PACAP-38-like immunoreactivity in the plasma during ictal and interictal periods of migraine patients Cephalalgia 33 2013 1085 1095
-
(2013)
Cephalalgia
, vol.33
, pp. 1085-1095
-
-
Tuka, B.1
Helyes, Z.2
Markovics, A.3
Bagoly, T.4
Szolcsanyi, J.5
Szabo, N.6
Toth, E.7
Kincses, Z.T.8
Vecsei, L.9
Tajti, J.10
-
75
-
-
0036260865
-
Neuropeptide expression in the human trigeminal nucleus caudalis and in the cervical spinal cord C1 and C2
-
R. Uddman, J. Tajti, M. Hou, F. Sundler, and L. Edvinsson Neuropeptide expression in the human trigeminal nucleus caudalis and in the cervical spinal cord C1 and C2 Cephalalgia 22 2002 112 116
-
(2002)
Cephalalgia
, vol.22
, pp. 112-116
-
-
Uddman, R.1
Tajti, J.2
Hou, M.3
Sundler, F.4
Edvinsson, L.5
-
76
-
-
84887643807
-
CGRP in the trigeminovascular system: A role for CGRP, adrenomedullin and amylin receptors?
-
C.S. Walker, and D.L. Hay CGRP in the trigeminovascular system: a role for CGRP, adrenomedullin and amylin receptors? Br. J. Pharmacol, Dec 2013; 170(7): 1293-1307 2013
-
(2013)
Br. J. Pharmacol, Dec 2013; 170(7): 1293-1307
-
-
Walker, C.S.1
Hay, D.L.2
-
77
-
-
70349922918
-
Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery
-
D. Vaudry, A. Falluel-Morel, S. Bourgault, M. Basille, D. Burel, O. Wurtz, A. Fournier, B.K. Chow, H. Hashimoto, L. Galas, and H. Vaudry Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery Pharmacol. Rev. 61 2009 283 357
-
(2009)
Pharmacol. Rev.
, vol.61
, pp. 283-357
-
-
Vaudry, D.1
Falluel-Morel, A.2
Bourgault, S.3
Basille, M.4
Burel, D.5
Wurtz, O.6
Fournier, A.7
Chow, B.K.8
Hashimoto, H.9
Galas, L.10
Vaudry, H.11
-
78
-
-
77950341045
-
Calcitonin gene-related peptide differentially regulates gene and protein expression in trigeminal glia cells: Findings from array analysis
-
C.V. Vause, and P.L. Durham Calcitonin gene-related peptide differentially regulates gene and protein expression in trigeminal glia cells: findings from array analysis Neurosci. Lett. 473 2010 163 167
-
(2010)
Neurosci. Lett.
, vol.473
, pp. 163-167
-
-
Vause, C.V.1
Durham, P.L.2
-
79
-
-
84923324741
-
PET imaging in healty subjects and migraineurs suggests CGRP receptor antagonists do not have to act centrally to achieve clinical efficacy
-
London, 20-23 September 2012, Poster number LB08 2012
-
Vermeersch S.D., De Saint-Huber B., Derdelinckx I.P.K., Stekers M.S.K., Bormans G., Reynders T., Declercq R., De Lepeleire I., Kennedy W.D., Blancard R., Marcantonio E., Hargreaves R.Li C.-C., Sanabria S., Hosteöer E., Joshi A.Evelhoch J.Van Laere K., (2012). PET imaging in healty subjects and migraineurs suggests CGRP receptor antagonists do not have to act centrally to achieve clinical efficacy. In: European Headache and Migraine Trust International Congress, London, 20-23 September 2012, Poster number LB08 2012.
-
(2012)
European Headache and Migraine Trust International Congress
-
-
De Saint-Huber, B.1
Derdelinckx, I.P.K.2
Stekers, M.S.K.3
Bormans, G.4
Reynders, T.5
Declercq, R.6
De Lepeleire, I.7
Kennedy, W.D.8
Blancard, R.9
Marcantonio, E.10
Hargreaves, R.11
Li, C.-C.12
Sanabria, S.13
Hosteöer, E.14
Joshi, A.15
Evelhoch, J.16
Van Laere, K.17
Vermeersch, S.D.18
-
81
-
-
43049119638
-
Release of glutamate and CGRP from trigeminal ganglion neurons: Role of calcium channels and 5-HT1 receptor signaling
-
Y. Xiao, J.A. Richter, and J.H. Hurley Release of glutamate and CGRP from trigeminal ganglion neurons: role of calcium channels and 5-HT1 receptor signaling Mol. Pain. 4 2008 12
-
(2008)
Mol. Pain.
, vol.4
, pp. 12
-
-
Xiao, Y.1
Richter, J.A.2
Hurley, J.H.3
-
82
-
-
33847790338
-
Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion
-
Z. Zhang, C.S. Winborn, B. Marquez de Prado, and A.F. Russo Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion J. Neurosci. 27 2007 2693 2703
-
(2007)
J. Neurosci.
, vol.27
, pp. 2693-2703
-
-
Zhang, Z.1
Winborn, C.S.2
Marquez De Prado, B.3
Russo, A.F.4
|