Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 30, 2015, Pages 9394-9399

  Wan, Chi Keung ^a   Andraski, Allison B ^a,c   Spolski, Rosanne ^a   Li, Peng ^a   Kazemian, Majid ^a   Oh, Jangsuk ^a   Samsel, Leigh ^a   Swanson, Phillip A ^b   McGavern, Dorian B ^b   Sampaio, Elizabeth P ^a   Freeman, Alexandra F ^a   Milner, Joshua D ^a   Holland, Steven M ^a   Leonard, Warren J ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

AD HIES; IFN ; IL 21; STATs; T cells

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR 1; INTERLEUKIN 10; INTERLEUKIN 21; STAT1 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR T BET; CYTOKINE; IMMUNOGLOBULIN E; INTERLEUKIN DERIVATIVE; STAT1 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FLOW CYTOMETRY; GAIN OF FUNCTION MUTATION; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPER IGE SYNDROME; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TH1 CELL; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CYTOLOGY; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; MUTATION; PHOSPHORYLATION; SEQUENCE ANALYSIS; TRANSGENIC MOUSE;

MUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CYTOKINES; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; IMMUNOGLOBULIN E; INTERFERON-GAMMA; INTERLEUKINS; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PHOSPHORYLATION; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; T-BOX DOMAIN PROTEINS;

EID: 84938099078     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1511711112     Document Type: Article

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