Pharmacophore Model for Wnt/Porcupine Inhibitors and Its Use in Drug Design

Journal of Chemical Information and Modeling

Volumn 55, Issue 7, 2015, Pages 1435-1448

  Poulsen, Anders ^a   Ho, Soo Yei ^a   Wang, Weiling ^a   Alam, Jenefer ^a   Jeyaraj, Duraiswamy A ^a   Ang, Shi Hua ^a   Tan, Eldwin Sum Wai ^a   Lin, Grace Ruiting ^a   Cheong, Vivien Wei Wen ^a   Ke, Zhiyuan ^a   Lee, May Ann ^a   Keller, Thomas H ^a  

^a Agency for Science   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; STEM CELLS;

ACYLTRANSFERASE; DRUG DESIGN; HIGH THROUGHPUT SCREENING; LOW-ENERGY CONFORMATIONS; MEMBRANE-BOUND; PHARMACOPHORE MODELING; PHARMACOPHORES; SELF RENEWAL;

PHARMACODYNAMICS;

MEMBRANE PROTEIN; PORCN PROTEIN, HUMAN; WNT PROTEIN;

ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CONFORMATION; DRUG DESIGN; ENZYME SPECIFICITY; HEK293 CELL LINE; HUMAN; STEREOISOMERISM;

DRUG DESIGN; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; STEREOISOMERISM; SUBSTRATE SPECIFICITY; WNT PROTEINS;

EID: 84938096785     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/acs.jcim.5b00159     Document Type: Article

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