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Colbert RA, Tran TM, Layh-Schmitt G. HLA-B27 misfolding and ankylosing spondylitis. Mol Immunol. 2014;57(1):44–51.
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(2014)
Mol Immunol
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Colbert, R.A.1
Tran, T.M.2
Layh-Schmitt, G.3
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70
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84893817150
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No evidence for a critical role of the unfolded protein response in synovium and blood of patients with ankylosing spondylitis
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PID: 24106049
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Neerinckx B, Carter S, Lories RJ. No evidence for a critical role of the unfolded protein response in synovium and blood of patients with ankylosing spondylitis. Ann Rheum Dis. 2014;73(3):629–30.
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(2014)
Ann Rheum Dis
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, pp. 629-630
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Neerinckx, B.1
Carter, S.2
Lories, R.J.3
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71
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84903907928
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Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation
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COI: 1:CAS:528:DC%2BC2cXhsFKntLjL, PID: 23740229
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Ciccia F, Accardo-Palumbo A, Rizzo A, Guggino G, Raimondo S, Giardina A, et al. Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation. Ann Rheum Dis. 2014;73(8):1566–74.
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(2014)
Ann Rheum Dis
, vol.73
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, pp. 1566-1574
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Ciccia, F.1
Accardo-Palumbo, A.2
Rizzo, A.3
Guggino, G.4
Raimondo, S.5
Giardina, A.6
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72
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84867525970
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Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis
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COI: 1:CAS:528:DC%2BC38XhsVeiu73J, PID: 22674414
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Utriainen L, Firmin D, Wright P, Cerovic V, Breban M, McInnes I, et al. Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis. Arthritis Rheum. 2012;64(10):3199–209.
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(2012)
Arthritis Rheum
, vol.64
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, pp. 3199-3209
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Utriainen, L.1
Firmin, D.2
Wright, P.3
Cerovic, V.4
Breban, M.5
McInnes, I.6
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73
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69449083847
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Dendritic cells from spondylarthritis-prone HLA-B27-transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and viability
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COI: 1:CAS:528:DC%2BD1MXht1WhtLjO, PID: 19714626
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Dhaenens M, Fert I, Glatigny S, Haerinck S, Poulain C, Donnadieu E, et al. Dendritic cells from spondylarthritis-prone HLA-B27-transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and viability. Arthritis Rheum. 2009;60(9):2622–32.
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(2009)
Arthritis Rheum
, vol.60
, Issue.9
, pp. 2622-2632
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Dhaenens, M.1
Fert, I.2
Glatigny, S.3
Haerinck, S.4
Poulain, C.5
Donnadieu, E.6
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74
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2342492839
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Defective costimulatory function is a striking feature of antigen-presenting cells in an HLA-B27-transgenic rat model of spondylarthropathy
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COI: 1:CAS:528:DC%2BD2cXkvFyrs7s%3D, PID: 15146433
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Hacquard-Bouder C, Falgarone G, Bosquet A, Smaoui F, Monnet D, Ittah M, et al. Defective costimulatory function is a striking feature of antigen-presenting cells in an HLA-B27-transgenic rat model of spondylarthropathy. Arthritis Rheum. 2004;50(5):1624–35.
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(2004)
Arthritis Rheum
, vol.50
, Issue.5
, pp. 1624-1635
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Hacquard-Bouder, C.1
Falgarone, G.2
Bosquet, A.3
Smaoui, F.4
Monnet, D.5
Ittah, M.6
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75
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34248589191
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Alteration of antigen-independent immunologic synapse formation between dendritic cells from HLA-B27-transgenic rats and CD4+ T cells: selective impairment of costimulatory molecule engagement by mature HLA-B27
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PID: 17469106
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Hacquard-Bouder C, Chimenti M-S, Giquel B, Donnadieu E, Fert I, Schmitt A, et al. Alteration of antigen-independent immunologic synapse formation between dendritic cells from HLA-B27-transgenic rats and CD4+ T cells: selective impairment of costimulatory molecule engagement by mature HLA-B27. Arthritis Rheum. 2007;56(5):1478–89.
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(2007)
Arthritis Rheum
, vol.56
, Issue.5
, pp. 1478-1489
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Hacquard-Bouder, C.1
Chimenti, M.-S.2
Giquel, B.3
Donnadieu, E.4
Fert, I.5
Schmitt, A.6
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76
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55849093579
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Correlation between dendritic cell functional defect and spondylarthritis phenotypes in HLA-B27/HUMAN beta2-microglobulin-transgenic rat lines
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COI: 1:CAS:528:DC%2BD1cXhsV2hs7nE, PID: 18975325
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Fert I, Glatigny S, Poulain C, Satumtira N, Dorris ML, Taurog JD, et al. Correlation between dendritic cell functional defect and spondylarthritis phenotypes in HLA-B27/HUMAN beta2-microglobulin-transgenic rat lines. Arthritis Rheum. 2008;58(11):3425–9.
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(2008)
Arthritis Rheum
, vol.58
, Issue.11
, pp. 3425-3429
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Fert, I.1
Glatigny, S.2
Poulain, C.3
Satumtira, N.4
Dorris, M.L.5
Taurog, J.D.6
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77
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84908090672
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Monocyte-derived dendritic cells from HLA-B27+ axial spondyloarthritis (SpA) patients display altered functional capacity and deregulated gene expression
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PID: 25142923
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Talpin A, Costantino F, Bonilla N, Leboime A, Letourneur F, Jacques S, et al. Monocyte-derived dendritic cells from HLA-B27+ axial spondyloarthritis (SpA) patients display altered functional capacity and deregulated gene expression. Arthritis Res Ther. 2014;16(4):417.
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(2014)
Arthritis Res Ther
, vol.16
, Issue.4
, pp. 417
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Talpin, A.1
Costantino, F.2
Bonilla, N.3
Leboime, A.4
Letourneur, F.5
Jacques, S.6
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78
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84898627352
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Reverse interferon signature is characteristic of antigen-presenting cells in human and rat spondyloarthritis
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COI: 1:CAS:528:DC%2BC2cXhtl2qtbnN, Interesting study showing that both HLA-B27 transgenic rat and SpA patient antigen-presenting cells share a striking « reverse » interferon signature
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Fert I, Cagnard N, Glatigny S, Letourneur F, Jacques S, Smith JA, et al. Reverse interferon signature is characteristic of antigen-presenting cells in human and rat spondyloarthritis. Arthritis Rheum Hoboken NJ. 2014;66(4):841–51. Interesting study showing that both HLA-B27 transgenic rat and SpA patient antigen-presenting cells share a striking « reverse » interferon signature.
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(2014)
Arthritis Rheum Hoboken NJ
, vol.66
, Issue.4
, pp. 841-851
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Fert, I.1
Cagnard, N.2
Glatigny, S.3
Letourneur, F.4
Jacques, S.5
Smith, J.A.6
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79
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Glatigny S, Fert I, Blaton MA, Lories RJ, Araujo LM, Chiocchia G, et al. Proinflammatory Th17 cells are expanded and induced by dendritic cells in spondylarthritis-prone HLA-B27-transgenic rats. Arthritis Rheum. 2012;64(1):110–20. This study shows that expression of HLA-B27 in transgenic rat dendritic cells results in a biased activation of CD4+ T cells towards pro-inflammatory Th17 effector profile
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Glatigny S, Fert I, Blaton MA, Lories RJ, Araujo LM, Chiocchia G, et al. Proinflammatory Th17 cells are expanded and induced by dendritic cells in spondylarthritis-prone HLA-B27-transgenic rats. Arthritis Rheum. 2012;64(1):110–20. This study shows that expression of HLA-B27 in transgenic rat dendritic cells results in a biased activation of CD4+ T cells towards pro-inflammatory Th17 effector profile.
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80
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84907392730
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Increased production of interleukin-17 over interleukin-10 by Treg cells implicates inducible costimulator molecule in experimental spondyloarthritis: imbalanced production of IL-10 and IL-17 by Treg cells from HLA-B27-transgenic rats
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COI: 1:CAS:528:DC%2BC2cXhvVSru77I
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Araujo LM, Fert I, Jouhault Q, Labroquère K, Andrieu M, Chiocchia G, et al. Increased production of interleukin-17 over interleukin-10 by Treg cells implicates inducible costimulator molecule in experimental spondyloarthritis: imbalanced production of IL-10 and IL-17 by Treg cells from HLA-B27-transgenic rats. Arthritis Rheum. 2014;66(9):2412–22.
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(2014)
Arthritis Rheum
, vol.66
, Issue.9
, pp. 2412-2422
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Araujo, L.M.1
Fert, I.2
Jouhault, Q.3
Labroquère, K.4
Andrieu, M.5
Chiocchia, G.6
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81
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HLA-B27 subtype oligomerization and intracellular accumulation patterns correlate with predisposition to spondyloarthritis
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COI: 1:CAS:528:DC%2BC2cXhs1Chs7rE, This study reports the intriguing observation that the intra-cellular behavior of SpA-associated HLA-B27 diverges from that of non-associated alleles by more persistent dimers and an accumulation in large saccules
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Jeanty C, Sourisce A, Noteuil A, Jah N, Wielgosik A, Fert I, et al. HLA-B27 subtype oligomerization and intracellular accumulation patterns correlate with predisposition to spondyloarthritis. Arthritis Rheum Hoboken NJ. 2014;66(8):2113–23. This study reports the intriguing observation that the intra-cellular behavior of SpA-associated HLA-B27 diverges from that of non-associated alleles by more persistent dimers and an accumulation in large saccules.
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(2014)
Arthritis Rheum Hoboken NJ
, vol.66
, Issue.8
, pp. 2113-2123
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Jeanty, C.1
Sourisce, A.2
Noteuil, A.3
Jah, N.4
Wielgosik, A.5
Fert, I.6
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82
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84857708456
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Enhanced phosphorylation of STAT-1 is dependent on double-stranded RNA-dependent protein kinase signaling in HLA-B27-expressing U937 monocytic cells
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COI: 1:CAS:528:DC%2BC38XivVGjtbo%3D, PID: 21968657
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Ruuska M, Sahlberg AS, Colbert RA, Granfors K, Penttinen MA. Enhanced phosphorylation of STAT-1 is dependent on double-stranded RNA-dependent protein kinase signaling in HLA-B27-expressing U937 monocytic cells. Arthritis Rheum. 2012;64(3):772–7.
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(2012)
Arthritis Rheum
, vol.64
, Issue.3
, pp. 772-777
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Ruuska, M.1
Sahlberg, A.S.2
Colbert, R.A.3
Granfors, K.4
Penttinen, M.A.5
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