The role of HLA genes in familial spondyloarthropathy: A comprehensive study of 70 multiplex families

Annals of the Rheumatic Diseases

Volumn 61, Issue 3, 2002, Pages 201-206

  Said Nahal, R ^a,b   Miceli Richard, C ^c,d   Gautreau, C ^c   Tamouza, R ^c   Borot, N ^e   Porcher, R ^c   Charron, D ^c   Dougados, M ^a,b   Breban, Maxime ^a,b  

^a AP HP Université René Descartes ^*  (France)

^b Groupe Français d'Etude Génétique des Spondylarthropathies GFEG   (France)

^c SAINT LOUIS HOSPITAL   (France)

^d Department of Orthopedic Surgery   (India)

^e CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B27 ANTIGEN; HLA C ANTIGEN; HLA DR ANTIGEN; HLA DR4 ANTIGEN;

ADULT; ALLELE; ANKYLOSING SPONDYLITIS; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE TRANSMISSION; FAMILIAL DISEASE; FAMILY STUDY; FEMALE; GENETIC LINKAGE; HAPLOTYPE; HLA TYPING; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SIBLING; SPINE DISEASE; SPONDYLOARTHROPATHY;

ADULT; ALLELES; BINOMIAL DISTRIBUTION; CHI-SQUARE DISTRIBUTION; CONFIDENCE INTERVALS; FEMALE; FRANCE; HAPLOTYPES; HLA ANTIGENS; HLA-A ANTIGENS; HLA-B27 ANTIGEN; HLA-C ANTIGENS; HLA-DR4 ANTIGEN; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; ODDS RATIO; PEDIGREE; SPONDYLARTHROPATHIES;

EID: 0036183453     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.61.3.201     Document Type: Article

References (28)

1. The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy
2. Associations between ankylosing spondylitis, psoriatic arthritis, Reiter's disease, the intestinal arthropathies, and Behçet's syndrome
3. Family studies in HLA-B27 associated arthritis
4. The familial form of spondylarthropathy: A clinical study of 115 multiplex families
5. Phenotypic diversity is not determined by independent genetic factors in familial spondylarthropathy
6. Impact of sex on inheritance of ankylosing spondylitis
7. HL-A antigen W27 - A genetic link between ankylosing spondylitis and Reiter's syndrome?
8. Susceptibility to ankylosing spondylitis in twins. The role of genes, HLA, and the environment
9. Whole-genome screening in ankylosing spondylitis: Evidence of non-MHC genetic-susceptibility loci
10. Investigating the genetic basis far ankylosing spondylitis. Linkage studies with the major histocompatibility complex region
11. Genes in the spondyloarthropathies
12. Critėre diagnostique des spondylarthropathies
13. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria
14. Reiter's syndrome. Evaluation of preliminary criteria for definite disease
15. Microdoplet assay of human serum cytotoxine
16. Analyse des données génétiques sur l'échantillon global des provinces Françaises
17. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
18. Application and interpretation of transmission/disequilibrium tests: Transmission of HLA-DQ haplotypes to unaffected siblings in 526 families with type 1 diabetes
19. HLA in ankylosing spondylitis: Is HLA-B27 the only MHC gene involved in disease pathogenesis
20. HLA-B27 alone rather than B27-related class I haplotypes contributes to ankylosing spondylitis susceptibility
21. The immunogenetics of the seronegative spondyloarthropathies
22. HLA-B27 haplotypes in family studies of ankylosing spondylitis
23. The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis
24. HLA-DR4 in ankylosing spondylitis with different patterns of joint involvement
25. Animal models of the spondyloarthropathies
26. The genetic contribution to the pathogenesis of rheumatoid arthritis
27. HLA antigens in rheumatoid arthritis patients with and without a family history of polyarthritis
28. HLA DR4 and B27 antigens in familial and sporadic rheumatoid arthritis