메뉴 건너뛰기




Volumn 35, Issue 3, 2015, Pages 222-236

APOL1 Kidney Disease Risk Variants: An Evolving Landscape

Author keywords

APOL1; Chronic kidney disease; Focal segmental glomerulosclerosis; Health disparities; Innate immunity

Indexed keywords

APOLIPOPROTEIN; APOLIPOPROTEIN L1; UNCLASSIFIED DRUG; APOL1 PROTEIN, HUMAN; HIGH DENSITY LIPOPROTEIN;

EID: 84937966279     PISSN: 02709295     EISSN: 15584488     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2015.04.008     Document Type: Review
Times cited : (130)

References (110)
  • 1
    • 84928480376 scopus 로고    scopus 로고
    • Annual data report: epidemiology of kidney disease in the United States
    • United States Renal Data System. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
    • United States Renal Data System. Annual data report: epidemiology of kidney disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. 2014.
    • (2014)
  • 2
    • 0036014946 scopus 로고    scopus 로고
    • Cumulative risk for developing end-stage renal disease in the US population
    • Kiberd B.A. Cumulative risk for developing end-stage renal disease in the US population. J Am Soc Nephrol 2002, 13:1635-1644.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1635-1644
    • Kiberd, B.A.1
  • 3
    • 77955646179 scopus 로고    scopus 로고
    • Association of trypanolytic ApoL1 variants with kidney disease in African Americans
    • Genovese G., Friedman D.J., Ross M.D., Lecordier L., Uzureau P., et al. Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science 2010, 329:841-845.
    • (2010) Science , vol.329 , pp. 841-845
    • Genovese, G.1    Friedman, D.J.2    Ross, M.D.3    Lecordier, L.4    Uzureau, P.5
  • 4
    • 80555136780 scopus 로고    scopus 로고
    • APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy
    • Kopp J.B., Nelson G.W., Sampath K., Johnson R.C., Genovese G., et al. APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy. J Am Soc Nephrol 2011, 22:2129-2137.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 2129-2137
    • Kopp, J.B.1    Nelson, G.W.2    Sampath, K.3    Johnson, R.C.4    Genovese, G.5
  • 6
    • 84906732058 scopus 로고    scopus 로고
    • APOL1 Kidney Risk Alleles: Population genetics and disease associations
    • Limou S., Nelson G.W., Kopp J.B., Winkler C.A. APOL1 Kidney Risk Alleles: Population genetics and disease associations. Adv Chronic Kidney Dis 2014, 21:426-433.
    • (2014) Adv Chronic Kidney Dis , vol.21 , pp. 426-433
    • Limou, S.1    Nelson, G.W.2    Kopp, J.B.3    Winkler, C.A.4
  • 7
    • 66049149084 scopus 로고    scopus 로고
    • The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions
    • Smith E.E., Malik H.S. The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions. Genome Res 2009, 19:850-858.
    • (2009) Genome Res , vol.19 , pp. 850-858
    • Smith, E.E.1    Malik, H.S.2
  • 8
    • 0035872826 scopus 로고    scopus 로고
    • The human apolipoprotein L gene cluster: identification, classification, and sites of distribution
    • Page N.M., Butlin D.J., Lomthaisong K., Lowry P.J. The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. Genomics 2001, 74:71-78.
    • (2001) Genomics , vol.74 , pp. 71-78
    • Page, N.M.1    Butlin, D.J.2    Lomthaisong, K.3    Lowry, P.J.4
  • 9
    • 84871582404 scopus 로고    scopus 로고
    • APOL1 null alleles from a rural village in India do not correlate with glomerulosclerosis
    • Johnstone D.B., Shegokar V., Nihalani D., Rathore Y.S., Mallik L., et al. APOL1 null alleles from a rural village in India do not correlate with glomerulosclerosis. PLoS One 2012, 7:e51546.
    • (2012) PLoS One , vol.7
    • Johnstone, D.B.1    Shegokar, V.2    Nihalani, D.3    Rathore, Y.S.4    Mallik, L.5
  • 10
    • 52049090825 scopus 로고    scopus 로고
    • Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell death
    • Wan G., Zhaorigetu S., Liu Z., Kaini R., Jiang Z., et al. Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell death. J Biol Chem 2008, 283:21540-21549.
    • (2008) J Biol Chem , vol.283 , pp. 21540-21549
    • Wan, G.1    Zhaorigetu, S.2    Liu, Z.3    Kaini, R.4    Jiang, Z.5
  • 11
    • 13244252344 scopus 로고    scopus 로고
    • Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells
    • Liu Z., Lu H., Jiang Z., Pastuszyn A., Hu C.A. Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells. Mol Cancer Res 2005, 3:21-31.
    • (2005) Mol Cancer Res , vol.3 , pp. 21-31
    • Liu, Z.1    Lu, H.2    Jiang, Z.3    Pastuszyn, A.4    Hu, C.A.5
  • 12
    • 79960998654 scopus 로고    scopus 로고
    • Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells
    • Zhaorigetu S., Yang Z., Toma I., McCaffrey T.A., Hu C.A. Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells. J Biol Chem 2011, 286:27389-27398.
    • (2011) J Biol Chem , vol.286 , pp. 27389-27398
    • Zhaorigetu, S.1    Yang, Z.2    Toma, I.3    McCaffrey, T.A.4    Hu, C.A.5
  • 13
    • 58149096404 scopus 로고    scopus 로고
    • ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death
    • Zhaorigetu S., Wan G., Kaini R., Jiang Z., Hu C.A. ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death. Autophagy 2008, 4:1079-1082.
    • (2008) Autophagy , vol.4 , pp. 1079-1082
    • Zhaorigetu, S.1    Wan, G.2    Kaini, R.3    Jiang, Z.4    Hu, C.A.5
  • 14
    • 84880274181 scopus 로고    scopus 로고
    • Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations
    • Ko W.Y., Rajan P., Gomez F., Scheinfeldt L., An P., et al. Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations. Am J Hum Genet 2013, 93:54-66.
    • (2013) Am J Hum Genet , vol.93 , pp. 54-66
    • Ko, W.Y.1    Rajan, P.2    Gomez, F.3    Scheinfeldt, L.4    An, P.5
  • 15
    • 84922128763 scopus 로고    scopus 로고
    • Innate immunity pathways regulate the nephropathy gene apolipoprotein L1
    • Nichols B., Jog P., Lee J.H., Blackler D., Wilmot M., et al. Innate immunity pathways regulate the nephropathy gene apolipoprotein L1. Kidney Int 2015, 87:332-342.
    • (2015) Kidney Int , vol.87 , pp. 332-342
    • Nichols, B.1    Jog, P.2    Lee, J.H.3    Blackler, D.4    Wilmot, M.5
  • 17
    • 22344443961 scopus 로고    scopus 로고
    • Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes
    • Perez-Morga D., Vanhollebeke B., Paturiaux-Hanocq F., Nolan D.P., Lins L., et al. Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. Science 2005, 309:469-472.
    • (2005) Science , vol.309 , pp. 469-472
    • Perez-Morga, D.1    Vanhollebeke, B.2    Paturiaux-Hanocq, F.3    Nolan, D.P.4    Lins, L.5
  • 19
    • 84924370994 scopus 로고    scopus 로고
    • Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: relevance to trypanosome lysis
    • Thomson R., Finkelstein A. Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: relevance to trypanosome lysis. Proc Natl Acad Sci U S A 2015, 112:2894-2899.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. 2894-2899
    • Thomson, R.1    Finkelstein, A.2
  • 20
    • 84875365804 scopus 로고    scopus 로고
    • Autophagosomes form at ER-mitochondria contact sites
    • Hamasaki M., Furuta N., Matsuda A., Nezu A., Yamamoto A., et al. Autophagosomes form at ER-mitochondria contact sites. Nature 2013, 495:389-393.
    • (2013) Nature , vol.495 , pp. 389-393
    • Hamasaki, M.1    Furuta, N.2    Matsuda, A.3    Nezu, A.4    Yamamoto, A.5
  • 22
    • 0034640281 scopus 로고    scopus 로고
    • Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
    • Oda E., Ohki R., Murasawa H., Nemoto J., Shibue T., et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000, 288:1053-1058.
    • (2000) Science , vol.288 , pp. 1053-1058
    • Oda, E.1    Ohki, R.2    Murasawa, H.3    Nemoto, J.4    Shibue, T.5
  • 23
    • 80053438209 scopus 로고    scopus 로고
    • Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1
    • Capewell P., Veitch N.J., Turner C.M., Raper J., Berriman M., et al. Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1. PLoS Negl Trop Dis 2011, 5:e1287.
    • (2011) PLoS Negl Trop Dis , vol.5
    • Capewell, P.1    Veitch, N.J.2    Turner, C.M.3    Raper, J.4    Berriman, M.5
  • 24
    • 59249090135 scopus 로고    scopus 로고
    • Trypanosome lytic factor, an antimicrobial high-density lipoprotein, ameliorates Leishmania infection
    • Samanovic M., Molina-Portela M.P., Chessler A.D., Burleigh B.A., Raper J. Trypanosome lytic factor, an antimicrobial high-density lipoprotein, ameliorates Leishmania infection. PLoS Pathog 2009, 5:e1000276.
    • (2009) PLoS Pathog , vol.5
    • Samanovic, M.1    Molina-Portela, M.P.2    Chessler, A.D.3    Burleigh, B.A.4    Raper, J.5
  • 25
    • 84890883324 scopus 로고    scopus 로고
    • The innate immune factor apolipoprotein L1 restricts HIV-1 infection
    • Taylor H.E., Khatua A.K., Popik W. The innate immune factor apolipoprotein L1 restricts HIV-1 infection. J Virol 2014, 88:592-603.
    • (2014) J Virol , vol.88 , pp. 592-603
    • Taylor, H.E.1    Khatua, A.K.2    Popik, W.3
  • 26
    • 84905223337 scopus 로고    scopus 로고
    • APOL1 risk variants enhance podocyte necrosis through compromising lysosomal membrane permeability
    • Lan X., Jhaveri A., Cheng K., Wen H., Saleem M.A., et al. APOL1 risk variants enhance podocyte necrosis through compromising lysosomal membrane permeability. Am J Physiol Renal Physiol 2014, 307:F326-F336.
    • (2014) Am J Physiol Renal Physiol , vol.307 , pp. F326-F336
    • Lan, X.1    Jhaveri, A.2    Cheng, K.3    Wen, H.4    Saleem, M.A.5
  • 27
    • 33748487618 scopus 로고    scopus 로고
    • The function of apolipoproteins L
    • Vanhollebeke B., Pays E. The function of apolipoproteins L. Cell Mol Life Sci 2006, 63:1937-1944.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 1937-1944
    • Vanhollebeke, B.1    Pays, E.2
  • 28
    • 84859264326 scopus 로고    scopus 로고
    • Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease
    • Hu C.A., Klopfer E.I., Ray P.E. Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease. FEBS Lett 2012, 586:947-955.
    • (2012) FEBS Lett , vol.586 , pp. 947-955
    • Hu, C.A.1    Klopfer, E.I.2    Ray, P.E.3
  • 29
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: their role in cell survival and cell death
    • Codogno P., Meijer A.J. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 2005, 12(Suppl 2):1509-1518.
    • (2005) Cell Death Differ , vol.12 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 30
    • 84924084673 scopus 로고    scopus 로고
    • Mechanisms and biological functions of autophagy in diseased and ageing kidneys
    • Fougeray S., Pallet N. Mechanisms and biological functions of autophagy in diseased and ageing kidneys. Nat Rev Nephrol 2015, 11:34-45.
    • (2015) Nat Rev Nephrol , vol.11 , pp. 34-45
    • Fougeray, S.1    Pallet, N.2
  • 31
    • 28544435485 scopus 로고    scopus 로고
    • Lysosomes and autophagy in cell death control
    • Kroemer G., Jaattela M. Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005, 5:886-897.
    • (2005) Nat Rev Cancer , vol.5 , pp. 886-897
    • Kroemer, G.1    Jaattela, M.2
  • 32
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
    • Wei M.C., Zong W.X., Cheng E.H., Lindsten T., Panoutsakopoulou V., et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001, 292:727-730.
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1    Zong, W.X.2    Cheng, E.H.3    Lindsten, T.4    Panoutsakopoulou, V.5
  • 33
    • 57149135309 scopus 로고    scopus 로고
    • Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax
    • Lovell J.F., Billen L.P., Bindner S., Shamas-Din A., Fradin C., et al. Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax. Cell 2008, 135:1074-1084.
    • (2008) Cell , vol.135 , pp. 1074-1084
    • Lovell, J.F.1    Billen, L.P.2    Bindner, S.3    Shamas-Din, A.4    Fradin, C.5
  • 34
    • 68249106060 scopus 로고    scopus 로고
    • BH3-only proteins in apoptosis and beyond: an overview
    • Lomonosova E., Chinnadurai G. BH3-only proteins in apoptosis and beyond: an overview. Oncogene 2008, 27(Suppl 1):S2-S19.
    • (2008) Oncogene , vol.27 , pp. S2-S19
    • Lomonosova, E.1    Chinnadurai, G.2
  • 35
    • 68149139456 scopus 로고    scopus 로고
    • The autophagy effector Beclin 1: a novel BH3-only protein
    • Sinha S., Levine B. The autophagy effector Beclin 1: a novel BH3-only protein. Oncogene 2008, 27(Suppl 1):S137-S148.
    • (2008) Oncogene , vol.27 , pp. S137-S148
    • Sinha, S.1    Levine, B.2
  • 36
    • 66349121718 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
    • Bellot G., Garcia-Medina R., Gounon P., Chiche J., Roux D., et al. Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol 2009, 29:2570-2581.
    • (2009) Mol Cell Biol , vol.29 , pp. 2570-2581
    • Bellot, G.1    Garcia-Medina, R.2    Gounon, P.3    Chiche, J.4    Roux, D.5
  • 37
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang R., Zeh H.J., Lotze M.T., Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011, 18:571-580.
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 38
    • 50249084987 scopus 로고    scopus 로고
    • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
    • Axe E.L., Walker S.A., Manifava M., Chandra P., Roderick H.L., et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008, 182:685-701.
    • (2008) J Cell Biol , vol.182 , pp. 685-701
    • Axe, E.L.1    Walker, S.A.2    Manifava, M.3    Chandra, P.4    Roderick, H.L.5
  • 39
    • 0030827971 scopus 로고    scopus 로고
    • BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity
    • Zha J., Harada H., Osipov K., Jockel J., Waksman G., et al. BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity. J Biol Chem 1997, 272:24101-24104.
    • (1997) J Biol Chem , vol.272 , pp. 24101-24104
    • Zha, J.1    Harada, H.2    Osipov, K.3    Jockel, J.4    Waksman, G.5
  • 40
    • 0035823238 scopus 로고    scopus 로고
    • Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
    • Puthalakath H., Villunger A., O'Reilly L.A., Beaumont J.G., Coultas L., et al. Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 2001, 293:1829-1832.
    • (2001) Science , vol.293 , pp. 1829-1832
    • Puthalakath, H.1    Villunger, A.2    O'Reilly, L.A.3    Beaumont, J.G.4    Coultas, L.5
  • 41
    • 85047695204 scopus 로고    scopus 로고
    • Proapoptotic activity of ITM2B(s), a BH3-only protein induced upon IL-2-deprivation which interacts with Bcl-2
    • Fleischer A., Ayllon V., Dumoutier L., Renauld J.C., Rebollo A. Proapoptotic activity of ITM2B(s), a BH3-only protein induced upon IL-2-deprivation which interacts with Bcl-2. Oncogene 2002, 21:3181-3189.
    • (2002) Oncogene , vol.21 , pp. 3181-3189
    • Fleischer, A.1    Ayllon, V.2    Dumoutier, L.3    Renauld, J.C.4    Rebollo, A.5
  • 42
    • 85042738678 scopus 로고    scopus 로고
    • BH3 domain-independent apolipoprotein L1 toxicity rescued by Bcl2 pro-survival proteins [abstract]
    • Heneghan J., Alper S., Pollak M. BH3 domain-independent apolipoprotein L1 toxicity rescued by Bcl2 pro-survival proteins [abstract]. J Am Soc Nephrol 2014, 25:452A.
    • (2014) J Am Soc Nephrol , vol.25
    • Heneghan, J.1    Alper, S.2    Pollak, M.3
  • 43
    • 74549217207 scopus 로고    scopus 로고
    • C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei and Trypanosoma brucei rhodesiense
    • Lecordier L., Vanhollebeke B., Poelvoorde P., Tebabi P., Paturiaux-Hanocq F., et al. C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei and Trypanosoma brucei rhodesiense. PLoS Pathog 2009, 5:e1000685.
    • (2009) PLoS Pathog , vol.5
    • Lecordier, L.1    Vanhollebeke, B.2    Poelvoorde, P.3    Tebabi, P.4    Paturiaux-Hanocq, F.5
  • 44
    • 84884402440 scopus 로고    scopus 로고
    • Mechanism of Trypanosoma brucei gambiense resistance to human serum
    • Uzureau P., Uzureau S., Lecordier L., Fontaine F., Tebabi P., et al. Mechanism of Trypanosoma brucei gambiense resistance to human serum. Nature 2013, 501:430-434.
    • (2013) Nature , vol.501 , pp. 430-434
    • Uzureau, P.1    Uzureau, S.2    Lecordier, L.3    Fontaine, F.4    Tebabi, P.5
  • 45
    • 27644537494 scopus 로고    scopus 로고
    • Trypanosome lytic factor, a subclass of high-density lipoprotein, forms cation-selective pores in membranes
    • Molina-Portela Mdel P., Lugli E.B., Recio-Pinto E., Raper J. Trypanosome lytic factor, a subclass of high-density lipoprotein, forms cation-selective pores in membranes. Mol Biochem Parasitol 2005, 144:218-226.
    • (2005) Mol Biochem Parasitol , vol.144 , pp. 218-226
    • Molina-Portela Mdel, P.1    Lugli, E.B.2    Recio-Pinto, E.3    Raper, J.4
  • 47
    • 84920185572 scopus 로고    scopus 로고
    • APOL1 associations with nephropathy, atherosclerosis, and all-cause mortality in African Americans with type 2 diabetes
    • Freedman B.I., Langefeld C.D., Lu L., Palmer N.D., Smith S.C., et al. APOL1 associations with nephropathy, atherosclerosis, and all-cause mortality in African Americans with type 2 diabetes. Kidney Int 2015, 87:176-181.
    • (2015) Kidney Int , vol.87 , pp. 176-181
    • Freedman, B.I.1    Langefeld, C.D.2    Lu, L.3    Palmer, N.D.4    Smith, S.C.5
  • 48
    • 84863186244 scopus 로고    scopus 로고
    • The APOL1 genotype of African American kidney transplant recipients does not impact 5-year allograft survival
    • Lee B.T., Kumar V., Williams T.A., Abdi R., Bernhardy A., et al. The APOL1 genotype of African American kidney transplant recipients does not impact 5-year allograft survival. Am J Transplant 2012, 12:1924-1928.
    • (2012) Am J Transplant , vol.12 , pp. 1924-1928
    • Lee, B.T.1    Kumar, V.2    Williams, T.A.3    Abdi, R.4    Bernhardy, A.5
  • 49
    • 49249111859 scopus 로고    scopus 로고
    • Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model
    • Molina-Portela M.P., Samanovic M., Raper J. Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model. J Exp Med 2008, 205:1721-1728.
    • (2008) J Exp Med , vol.205 , pp. 1721-1728
    • Molina-Portela, M.P.1    Samanovic, M.2    Raper, J.3
  • 50
    • 84923923112 scopus 로고    scopus 로고
    • Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines
    • Ma L., Shelness G.S., Snipes J.A., Murea M., Antinozzi P.A., et al. Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines. J Am Soc Nephrol 2015, 26:339-348.
    • (2015) J Am Soc Nephrol , vol.26 , pp. 339-348
    • Ma, L.1    Shelness, G.S.2    Snipes, J.A.3    Murea, M.4    Antinozzi, P.A.5
  • 51
    • 29244477844 scopus 로고    scopus 로고
    • A human protein atlas for normal and cancer tissues based on antibody proteomics
    • Uhlen M., Bjorling E., Agaton C., Szigyarto C.A., Amini B., et al. A human protein atlas for normal and cancer tissues based on antibody proteomics. Mol Cell Proteomics 2005, 4:1920-1932.
    • (2005) Mol Cell Proteomics , vol.4 , pp. 1920-1932
    • Uhlen, M.1    Bjorling, E.2    Agaton, C.3    Szigyarto, C.A.4    Amini, B.5
  • 53
    • 84934440545 scopus 로고    scopus 로고
    • APOL1 toxin, innate immunity, and kidney injury
    • Apr 8. [Epub ahead of print].
    • Limou S, Dummer PD, Nelson GW, Kopp JB, Winkler CA. APOL1 toxin, innate immunity, and kidney injury. Kidney Int. 2015 Apr 8. [Epub ahead of print]. http://dx.doi.org/10.1038/ki.2015.109.
    • (2015) Kidney Int
    • Limou, S.1    Dummer, P.D.2    Nelson, G.W.3    Kopp, J.B.4    Winkler, C.A.5
  • 54
    • 85042736123 scopus 로고    scopus 로고
    • APOL1 Is an innate immunity effector that induces stress autophagy by interacting with the SNARE Protein,VAMP8 [Abstract]. ASN Annual Meeting
    • MS
    • O'Toole JF MS, Thomas DB, Barisoni L, Bruggeman LA, Sedor JR. APOL1 Is an innate immunity effector that induces stress autophagy by interacting with the SNARE Protein,VAMP8 [Abstract]. ASN Annual Meeting. Atlanta, GA J Am Soc Nephrol. 2013;24:93A.
    • (2013) Atlanta, GA J Am Soc Nephrol , vol.24
    • O'Toole, J.F.1    Thomas, D.B.2    Barisoni, L.3    Bruggeman, L.A.4    Sedor, J.R.5
  • 55
    • 79960301464 scopus 로고    scopus 로고
    • Topological arrangement of the intracellular membrane fusion machinery
    • Rathore S.S., Ghosh N., Ouyang Y., Shen J. Topological arrangement of the intracellular membrane fusion machinery. Mol Biol Cell 2011, 22:2612-2619.
    • (2011) Mol Biol Cell , vol.22 , pp. 2612-2619
    • Rathore, S.S.1    Ghosh, N.2    Ouyang, Y.3    Shen, J.4
  • 56
    • 66349083560 scopus 로고    scopus 로고
    • Proteomic analysis of defined HDL subpopulations reveals particle-specific protein clusters: relevance to antioxidative function
    • Davidson W.S., Silva R.A., Chantepie S., Lagor W.R., Chapman M.J., et al. Proteomic analysis of defined HDL subpopulations reveals particle-specific protein clusters: relevance to antioxidative function. Arterioscler Thromb Vasc Biol 2009, 29:870-876.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 870-876
    • Davidson, W.S.1    Silva, R.A.2    Chantepie, S.3    Lagor, W.R.4    Chapman, M.J.5
  • 57
    • 0033003710 scopus 로고    scopus 로고
    • Characterization of a novel trypanosome lytic factor from human serum
    • Raper J., Fung R., Ghiso J., Nussenzweig V., Tomlinson S. Characterization of a novel trypanosome lytic factor from human serum. Infect Immun 1999, 67:1910-1916.
    • (1999) Infect Immun , vol.67 , pp. 1910-1916
    • Raper, J.1    Fung, R.2    Ghiso, J.3    Nussenzweig, V.4    Tomlinson, S.5
  • 58
    • 0024595168 scopus 로고
    • Lysis of Trypanosoma-brucei by a toxic subspecies of human high-density lipoprotein
    • Hajduk S.L., Moore D.R., Vasudevacharya J., Siqueira H., Torri A.F., et al. Lysis of Trypanosoma-brucei by a toxic subspecies of human high-density lipoprotein. J Biol Chem 1989, 264:5210-5217.
    • (1989) J Biol Chem , vol.264 , pp. 5210-5217
    • Hajduk, S.L.1    Moore, D.R.2    Vasudevacharya, J.3    Siqueira, H.4    Torri, A.F.5
  • 60
    • 84922662477 scopus 로고    scopus 로고
    • A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome
    • Capewell P., Cooper A., Clucas C., Weir W., Macleod A. A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome. Parasitology 2015, 142(Suppl 1):S108-S119.
    • (2015) Parasitology , vol.142 , pp. S108-S119
    • Capewell, P.1    Cooper, A.2    Clucas, C.3    Weir, W.4    Macleod, A.5
  • 61
    • 77955927884 scopus 로고    scopus 로고
    • The trypanolytic factor-mechanism, impacts and applications
    • Wheeler R.J. The trypanolytic factor-mechanism, impacts and applications. Trends Parasitol 2010, 26:457-464.
    • (2010) Trends Parasitol , vol.26 , pp. 457-464
    • Wheeler, R.J.1
  • 62
    • 84869402322 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory role of paraoxonase 1: implication in arteriosclerosis diseases
    • Litvinov D., Mahini H., Garelnabi M. Antioxidant and anti-inflammatory role of paraoxonase 1: implication in arteriosclerosis diseases. N Am J Med Sci 2012, 4:523-532.
    • (2012) N Am J Med Sci , vol.4 , pp. 523-532
    • Litvinov, D.1    Mahini, H.2    Garelnabi, M.3
  • 63
    • 24144442921 scopus 로고    scopus 로고
    • Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL
    • Albert T.S., Duchateau P.N., Deeb S.S., Pullinger C.R., Cho M.H., et al. Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL. J Lipid Res 2005, 46:469-474.
    • (2005) J Lipid Res , vol.46 , pp. 469-474
    • Albert, T.S.1    Duchateau, P.N.2    Deeb, S.S.3    Pullinger, C.R.4    Cho, M.H.5
  • 65
    • 0033846760 scopus 로고    scopus 로고
    • Plasma apolipoprotein L concentrations correlate with plasma triglycerides and cholesterol levels in normolipidemic, hyperlipidemic, and diabetic subjects
    • Duchateau P.N., Movsesyan I., Yamashita S., Sakai N., Hirano K., et al. Plasma apolipoprotein L concentrations correlate with plasma triglycerides and cholesterol levels in normolipidemic, hyperlipidemic, and diabetic subjects. J Lipid Res 2000, 41:1231-1236.
    • (2000) J Lipid Res , vol.41 , pp. 1231-1236
    • Duchateau, P.N.1    Movsesyan, I.2    Yamashita, S.3    Sakai, N.4    Hirano, K.5
  • 66
    • 84867305299 scopus 로고    scopus 로고
    • Variation in APOL1 contributes to ancestry-level differences in HDLc-kidney function association
    • Bentley A.R., Doumatey A.P., Chen G., Huang H., Zhou J., et al. Variation in APOL1 contributes to ancestry-level differences in HDLc-kidney function association. Int J Nephrol 2012, 2012:748984.
    • (2012) Int J Nephrol , vol.2012
    • Bentley, A.R.1    Doumatey, A.P.2    Chen, G.3    Huang, H.4    Zhou, J.5
  • 67
    • 80155172526 scopus 로고    scopus 로고
    • Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans
    • Freedman B.I., Langefeld C.D., Murea M., Ma L., Otvos J.D., et al. Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans. Nephrol Dial Transplant 2011, 26:3805-3810.
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 3805-3810
    • Freedman, B.I.1    Langefeld, C.D.2    Murea, M.3    Ma, L.4    Otvos, J.D.5
  • 68
    • 0036212122 scopus 로고    scopus 로고
    • The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue
    • Monajemi H., Fontijn R.D., Pannekoek H., Horrevoets A.J. The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue. Genomics 2002, 79:539-546.
    • (2002) Genomics , vol.79 , pp. 539-546
    • Monajemi, H.1    Fontijn, R.D.2    Pannekoek, H.3    Horrevoets, A.J.4
  • 69
    • 0035061243 scopus 로고    scopus 로고
    • Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene
    • Duchateau P.N., Pullinger C.R., Cho M.H., Eng C., Kane J.P. Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. J Lipid Res 2001, 42:620-630.
    • (2001) J Lipid Res , vol.42 , pp. 620-630
    • Duchateau, P.N.1    Pullinger, C.R.2    Cho, M.H.3    Eng, C.4    Kane, J.P.5
  • 70
    • 78649653622 scopus 로고    scopus 로고
    • A novel anti-apoptotic role for apolipoprotein L2 in IFN-gamma-induced cytotoxicity in human bronchial epithelial cells
    • Liao W., Goh F.Y., Betts R.J., Kemeny D.M., Tam J., et al. A novel anti-apoptotic role for apolipoprotein L2 in IFN-gamma-induced cytotoxicity in human bronchial epithelial cells. J Cell Physiol 2011, 226:397-406.
    • (2011) J Cell Physiol , vol.226 , pp. 397-406
    • Liao, W.1    Goh, F.Y.2    Betts, R.J.3    Kemeny, D.M.4    Tam, J.5
  • 71
    • 84888636557 scopus 로고    scopus 로고
    • JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy
    • Divers J., Nunez M., High K.P., Murea M., Rocco M.V., et al. JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy. Kidney Int 2013, 84:1207-1213.
    • (2013) Kidney Int , vol.84 , pp. 1207-1213
    • Divers, J.1    Nunez, M.2    High, K.P.3    Murea, M.4    Rocco, M.V.5
  • 72
    • 18344369874 scopus 로고    scopus 로고
    • Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22
    • Mimmack M.L., Ryan M., Baba H., Navarro-Ruiz J., Iritani S., et al. Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22. Proc Natl Acad Sci U S A 2002, 99:4680-4685.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4680-4685
    • Mimmack, M.L.1    Ryan, M.2    Baba, H.3    Navarro-Ruiz, J.4    Iritani, S.5
  • 73
    • 84886651067 scopus 로고    scopus 로고
    • Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia
    • Hwang Y., Kim J., Shin J.Y., Kim J.I., Seo J.S., et al. Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia. Transl Psychiatry 2013, 3:e321.
    • (2013) Transl Psychiatry , vol.3
    • Hwang, Y.1    Kim, J.2    Shin, J.Y.3    Kim, J.I.4    Seo, J.S.5
  • 74
    • 34248192332 scopus 로고    scopus 로고
    • Association study between Apolipoprotein L and schizophrenia by exhaustive and rule-based combination analysis for identification of multilocus interactions
    • Tomita Y., Ikeda M., Mutoh H., Inada T., Iwata N., et al. Association study between Apolipoprotein L and schizophrenia by exhaustive and rule-based combination analysis for identification of multilocus interactions. J Biosci Bioeng 2007, 103:303-310.
    • (2007) J Biosci Bioeng , vol.103 , pp. 303-310
    • Tomita, Y.1    Ikeda, M.2    Mutoh, H.3    Inada, T.4    Iwata, N.5
  • 76
    • 77956191258 scopus 로고    scopus 로고
    • Testing the antagonistic pleiotropy model of schizophrenia susceptibility by analysis of DAOA, PPP1R1B, and APOL1 genes
    • Carrera N., Arrojo M., Paz E., Ramos-Rios R., Agra S., et al. Testing the antagonistic pleiotropy model of schizophrenia susceptibility by analysis of DAOA, PPP1R1B, and APOL1 genes. Psychiatry Res 2010, 179:126-129.
    • (2010) Psychiatry Res , vol.179 , pp. 126-129
    • Carrera, N.1    Arrojo, M.2    Paz, E.3    Ramos-Rios, R.4    Agra, S.5
  • 77
    • 20444398843 scopus 로고    scopus 로고
    • Investigation of the apolipoprotein-L (APOL) gene family and schizophrenia using a novel DNA pooling strategy for public database SNPs
    • McGhee K.A., Morris D.W., Schwaiger S., Nangle J.M., Donohoe G., et al. Investigation of the apolipoprotein-L (APOL) gene family and schizophrenia using a novel DNA pooling strategy for public database SNPs. Schizophr Res 2005, 76:231-238.
    • (2005) Schizophr Res , vol.76 , pp. 231-238
    • McGhee, K.A.1    Morris, D.W.2    Schwaiger, S.3    Nangle, J.M.4    Donohoe, G.5
  • 78
    • 50249175563 scopus 로고    scopus 로고
    • Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia
    • Takahashi S., Cui Y.H., Han Y.H., Fagerness J.A., Galloway B., et al. Association of SNPs and haplotypes in APOL1, 2 and 4 with schizophrenia. Schizophr Res 2008, 104:153-164.
    • (2008) Schizophr Res , vol.104 , pp. 153-164
    • Takahashi, S.1    Cui, Y.H.2    Han, Y.H.3    Fagerness, J.A.4    Galloway, B.5
  • 79
    • 0036773265 scopus 로고    scopus 로고
    • The neurobiology of apolipoproteins in psychiatric disorders
    • Sutcliffe J.G., Thomas E.A. The neurobiology of apolipoproteins in psychiatric disorders. Mol Neurobiol 2002, 26:369-388.
    • (2002) Mol Neurobiol , vol.26 , pp. 369-388
    • Sutcliffe, J.G.1    Thomas, E.A.2
  • 80
    • 33845670760 scopus 로고    scopus 로고
    • Glomerular podocytes contain neuron-like functional synaptic vesicles
    • Rastaldi M.P., Armelloni S., Berra S., Calvaresi N., Corbelli A., et al. Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J 2006, 20:976-978.
    • (2006) FASEB J , vol.20 , pp. 976-978
    • Rastaldi, M.P.1    Armelloni, S.2    Berra, S.3    Calvaresi, N.4    Corbelli, A.5
  • 81
    • 84871764943 scopus 로고    scopus 로고
    • Neuronal proteins are novel components of podocyte major processes and their expression in glomerular crescents supports their role in crescent formation
    • Sistani L., Rodriguez P.Q., Hultenby K., Uhlen M., Betsholtz C., et al. Neuronal proteins are novel components of podocyte major processes and their expression in glomerular crescents supports their role in crescent formation. Kidney Int 2013, 83:63-71.
    • (2013) Kidney Int , vol.83 , pp. 63-71
    • Sistani, L.1    Rodriguez, P.Q.2    Hultenby, K.3    Uhlen, M.4    Betsholtz, C.5
  • 82
    • 0037093347 scopus 로고    scopus 로고
    • Mechanism of the process formation; podocytes vs. neurons
    • Kobayashi N. Mechanism of the process formation; podocytes vs. neurons. Microsc Res Tech 2002, 57:217-223.
    • (2002) Microsc Res Tech , vol.57 , pp. 217-223
    • Kobayashi, N.1
  • 83
    • 84859361685 scopus 로고    scopus 로고
    • The new era of APOL1-associated glomerulosclerosis
    • Freedman B.I., Langefeld C.D. The new era of APOL1-associated glomerulosclerosis. Nephrol Dial Transplant 2012, 27:1288-1291.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 1288-1291
    • Freedman, B.I.1    Langefeld, C.D.2
  • 84
    • 84937983933 scopus 로고    scopus 로고
    • APOL1 risk alleles are associated with exaggerated age-related changes in glomerular number and volume in African American adults: an autopsy study
    • Jun 2. [Epub ahead of print].
    • Hoy WE, Hughson MD, Kopp JB, Mott SA, Bertram JF, et al. APOL1 risk alleles are associated with exaggerated age-related changes in glomerular number and volume in African American adults: an autopsy study. J Am Soc Nephrol. 2015 Jun 2. pii: ASN.2014080768 [Epub ahead of print].
    • (2015) J Am Soc Nephrol
    • Hoy, W.E.1    Hughson, M.D.2    Kopp, J.B.3    Mott, S.A.4    Bertram, J.F.5
  • 85
    • 84863810792 scopus 로고    scopus 로고
    • HIV-associated nephropathy patients with and without apolipoprotein L1 gene variants have similar clinical and pathological characteristics
    • Atta M.G., Estrella M.M., Kuperman M., Foy M.C., Fine D.M., et al. HIV-associated nephropathy patients with and without apolipoprotein L1 gene variants have similar clinical and pathological characteristics. Kidney Int 2012, 82:338-343.
    • (2012) Kidney Int , vol.82 , pp. 338-343
    • Atta, M.G.1    Estrella, M.M.2    Kuperman, M.3    Foy, M.C.4    Fine, D.M.5
  • 86
    • 84856840591 scopus 로고    scopus 로고
    • APOL1 risk variants predict histopathology and progression to ESRD in HIV-related kidney disease
    • Fine D.M., Wasser W.G., Estrella M.M., Atta M.G., Kuperman M., et al. APOL1 risk variants predict histopathology and progression to ESRD in HIV-related kidney disease. J Am Soc Nephrol 2012, 23:343-350.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 343-350
    • Fine, D.M.1    Wasser, W.G.2    Estrella, M.M.3    Atta, M.G.4    Kuperman, M.5
  • 87
    • 84885307156 scopus 로고    scopus 로고
    • Host APOL1 genotype is independently associated with proteinuria in HIV infection
    • Estrella M.M., Wyatt C.M., Pearce C.L., Li M., Shlipak M.G., et al. Host APOL1 genotype is independently associated with proteinuria in HIV infection. Kidney Int 2013, 84:834-840.
    • (2013) Kidney Int , vol.84 , pp. 834-840
    • Estrella, M.M.1    Wyatt, C.M.2    Pearce, C.L.3    Li, M.4    Shlipak, M.G.5
  • 88
    • 84935037203 scopus 로고    scopus 로고
    • APOL1 risk variants are strongly associated with HIV-associated nephropathy in black South Africans
    • In press
    • Kasembeli A.N., Duarte R., Ramsay M., Mosiane P., Dickens C., et al. APOL1 risk variants are strongly associated with HIV-associated nephropathy in black South Africans. J Am Soc Nephrol 2015, In press.
    • (2015) J Am Soc Nephrol
    • Kasembeli, A.N.1    Duarte, R.2    Ramsay, M.3    Mosiane, P.4    Dickens, C.5
  • 89
    • 80555134767 scopus 로고    scopus 로고
    • APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy
    • Papeta N., Kiryluk K., Patel A., Sterken R., Kacak N., et al. APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy. J Am Soc Nephrol 2011, 22:1991-1996.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1991-1996
    • Papeta, N.1    Kiryluk, K.2    Patel, A.3    Sterken, R.4    Kacak, N.5
  • 90
    • 84930447149 scopus 로고    scopus 로고
    • Clinical features and histology of apolipoprotein L1-associated nephropathy in the FSGS Clinical Trial
    • In press
    • Kopp J.B., Winkler C.A., Zhao X., Radeva M.K., Gassman J.J., et al. Clinical features and histology of apolipoprotein L1-associated nephropathy in the FSGS Clinical Trial. J Am Soc Nephrol 2015, In press.
    • (2015) J Am Soc Nephrol
    • Kopp, J.B.1    Winkler, C.A.2    Zhao, X.3    Radeva, M.K.4    Gassman, J.J.5
  • 92
    • 84871798567 scopus 로고    scopus 로고
    • Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans
    • Lipkowitz M.S., Freedman B.I., Langefeld C.D., Comeau M.E., Bowden D.W., et al. Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans. Kidney Int 2013, 83:114-120.
    • (2013) Kidney Int , vol.83 , pp. 114-120
    • Lipkowitz, M.S.1    Freedman, B.I.2    Langefeld, C.D.3    Comeau, M.E.4    Bowden, D.W.5
  • 94
    • 84877094422 scopus 로고    scopus 로고
    • Apolipoprotein L1 risk variants associate with systemic lupus erythematosus-associated collapsing glomerulopathy
    • Larsen C.P., Beggs M.L., Saeed M., Walker P.D. Apolipoprotein L1 risk variants associate with systemic lupus erythematosus-associated collapsing glomerulopathy. J Am Soc Nephrol 2013, 24:722-725.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 722-725
    • Larsen, C.P.1    Beggs, M.L.2    Saeed, M.3    Walker, P.D.4
  • 95
    • 84875462369 scopus 로고    scopus 로고
    • Endoplasmic reticulum-endosome contact increases as endosomes traffic and mature
    • Friedman J.R., Dibenedetto J.R., West M., Rowland A.A., Voeltz G.K. Endoplasmic reticulum-endosome contact increases as endosomes traffic and mature. Mol Biol Cell 2013, 24:1030-1040.
    • (2013) Mol Biol Cell , vol.24 , pp. 1030-1040
    • Friedman, J.R.1    Dibenedetto, J.R.2    West, M.3    Rowland, A.A.4    Voeltz, G.K.5
  • 96
    • 84884327585 scopus 로고    scopus 로고
    • APOL1 variants associate with increased risk of CKD among African Americans
    • Foster M.C., Coresh J., Fornage M., Astor B.C., Grams M., et al. APOL1 variants associate with increased risk of CKD among African Americans. J Am Soc Nephrol 2013, 24:1484-1491.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 1484-1491
    • Foster, M.C.1    Coresh, J.2    Fornage, M.3    Astor, B.C.4    Grams, M.5
  • 97
    • 84882411620 scopus 로고    scopus 로고
    • High population frequencies of APOL1 risk variants are associated with increased prevalence of non-diabetic chronic kidney disease in the Igbo people from south-eastern Nigeria
    • Ulasi II M., Tzur S., Wasser W.G., Shemer R., Kruzel E., et al. High population frequencies of APOL1 risk variants are associated with increased prevalence of non-diabetic chronic kidney disease in the Igbo people from south-eastern Nigeria. Nephron Clin Pract 2013, 123:123-128.
    • (2013) Nephron Clin Pract , vol.123 , pp. 123-128
    • Ulasi, M.1    Tzur, S.2    Wasser, W.G.3    Shemer, R.4    Kruzel, E.5
  • 98
    • 80555148890 scopus 로고    scopus 로고
    • Genetic variation in APOL1 associates with younger age at hemodialysis initiation
    • Kanji Z., Powe C.E., Wenger J.B., Huang C., Ankers E., et al. Genetic variation in APOL1 associates with younger age at hemodialysis initiation. J Am Soc Nephrol 2011, 22:2091-2097.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 2091-2097
    • Kanji, Z.1    Powe, C.E.2    Wenger, J.B.3    Huang, C.4    Ankers, E.5
  • 99
    • 84859338200 scopus 로고    scopus 로고
    • APOL1 allelic variants are associated with lower age of dialysis initiation and thereby increased dialysis vintage in African and Hispanic Americans with non-diabetic end-stage kidney disease
    • Tzur S., Rosset S., Skorecki K., Wasser W.G. APOL1 allelic variants are associated with lower age of dialysis initiation and thereby increased dialysis vintage in African and Hispanic Americans with non-diabetic end-stage kidney disease. Nephrol Dial Transplant 2012, 27:1498-1505.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 1498-1505
    • Tzur, S.1    Rosset, S.2    Skorecki, K.3    Wasser, W.G.4
  • 100
    • 84867809075 scopus 로고    scopus 로고
    • Collapsing glomerulopathy associated lupus in a black female with homozygous APOL1 mutation
    • Kofman T., Narjoz C., Raimbourg Q., Loriot M.A., Karras A., et al. Collapsing glomerulopathy associated lupus in a black female with homozygous APOL1 mutation. Lupus 2012, 21:1459-1462.
    • (2012) Lupus , vol.21 , pp. 1459-1462
    • Kofman, T.1    Narjoz, C.2    Raimbourg, Q.3    Loriot, M.A.4    Karras, A.5
  • 101
    • 84903280268 scopus 로고    scopus 로고
    • Histopathologic effect of APOL1 risk alleles in PLA2R-associated membranous glomerulopathy
    • Larsen C.P., Beggs M.L., Walker P.D., Saeed M., Ambruzs J.M., et al. Histopathologic effect of APOL1 risk alleles in PLA2R-associated membranous glomerulopathy. Am J Kidney Dis 2014, 64:161-163.
    • (2014) Am J Kidney Dis , vol.64 , pp. 161-163
    • Larsen, C.P.1    Beggs, M.L.2    Walker, P.D.3    Saeed, M.4    Ambruzs, J.M.5
  • 103
    • 84895826536 scopus 로고    scopus 로고
    • Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease
    • Palmer N.D., Ng M.C., Hicks P.J., Mudgal P., Langefeld C.D., et al. Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease. PLoS One 2014, 9:e88273.
    • (2014) PLoS One , vol.9
    • Palmer, N.D.1    Ng, M.C.2    Hicks, P.J.3    Mudgal, P.4    Langefeld, C.D.5
  • 104
    • 84895927552 scopus 로고    scopus 로고
    • Increased burden of cardiovascular disease in carriers of APOL1 genetic variants
    • Ito K., Bick A.G., Flannick J., Friedman D.J., Genovese G., et al. Increased burden of cardiovascular disease in carriers of APOL1 genetic variants. Circ Res 2014, 114:845-850.
    • (2014) Circ Res , vol.114 , pp. 845-850
    • Ito, K.1    Bick, A.G.2    Flannick, J.3    Friedman, D.J.4    Genovese, G.5
  • 105
    • 84920128507 scopus 로고    scopus 로고
    • Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial
    • Langefeld C.D., Divers J., Pajewski N.M., Hawfield A.T., Reboussin D.M., et al. Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. Kidney Int 2015, 87:169-175.
    • (2015) Kidney Int , vol.87 , pp. 169-175
    • Langefeld, C.D.1    Divers, J.2    Pajewski, N.M.3    Hawfield, A.T.4    Reboussin, D.M.5
  • 106
    • 84889260719 scopus 로고    scopus 로고
    • APOL1 risk variants, race, and progression of chronic kidney disease
    • Parsa A., Kao W.H., Xie D., Astor B.C., Li M., et al. APOL1 risk variants, race, and progression of chronic kidney disease. N Engl J Med 2013, 369:2183-2196.
    • (2013) N Engl J Med , vol.369 , pp. 2183-2196
    • Parsa, A.1    Kao, W.H.2    Xie, D.3    Astor, B.C.4    Li, M.5
  • 108
    • 84892407811 scopus 로고    scopus 로고
    • Skylign: a tool for creating informative, interactive logos representing sequence alignments and profile hidden Markov models
    • Wheeler T.J., Clements J., Finn R.D. Skylign: a tool for creating informative, interactive logos representing sequence alignments and profile hidden Markov models. BMC Bioinformatics 2014, 15:7.
    • (2014) BMC Bioinformatics , vol.15 , pp. 7
    • Wheeler, T.J.1    Clements, J.2    Finn, R.D.3
  • 110
    • 84946074739 scopus 로고    scopus 로고
    • The InterPro protein families database: the classification resource after 15 years
    • Mitchell A., Chang H.Y., Daugherty L., Fraser M., Hunter S., et al. The InterPro protein families database: the classification resource after 15 years. Nucleic Acids Res 2015, 43:D213-D221.
    • (2015) Nucleic Acids Res , vol.43 , pp. D213-D221
    • Mitchell, A.1    Chang, H.Y.2    Daugherty, L.3    Fraser, M.4    Hunter, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.