Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks beclin 1-dependent autophagy in atherosclerotic cells

Journal of Biological Chemistry

Volumn 286, Issue 31, 2011, Pages 27389-27398

  Zhaorigetu, Siqin ^a   Yang, Zhaoqing ^b   Toma, Ian ^a,b   McCaffrey, Timothy A ^b   Hu, Chien An A ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEINS; ATHEROSCLEROTIC LESIONS; AUTOPHAGY; BCL-2 FAMILY; CARDIO-VASCULAR DISEASE; CASPASE ACTIVATION; CASPASE INHIBITORS; CASPASE-3; DOWNSTREAM TARGET; INDUCED APOPTOSIS; OVER-EXPRESSION; PLAQUE RUPTURE; REACTIVE OXYGEN SPECIES; SMOOTH MUSCLE CELLS; THERAPEUTIC TARGETS; VASCULAR CELLS;

DISEASES;

CELL DEATH;

APOLIPOPROTEIN; APOLIPOPROTEIN C3; APOLIPOPROTEIN L6; BECLIN 1; CASPASE 3; CASPASE INHIBITOR; FAS ANTIGEN; GAMMA INTERFERON; PROTEIN BCL XL; PROTEIN P62; REACTIVE OXYGEN METABOLITE; SCAVENGER; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; AUTOPHAGY; BIOACCUMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LOCALIZATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SMOOTH MUSCLE FIBER;

ANTIOXIDANTS; APOLIPOPROTEINS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ATHEROSCLEROSIS; AUTOPHAGY; BCL-X PROTEIN; CELLS, CULTURED; GENE KNOCKDOWN TECHNIQUES; HUMANS; MEMBRANE PROTEINS; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 79960998654     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.210245     Document Type: Article

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