메뉴 건너뛰기




Volumn 45, Issue 7, 2015, Pages 578-585

Interaction between oblongifolin C and UDP-glucuronosyltransferase isoforms in human liver and intestine microsomes

Author keywords

Drug drug interactions; Glucuronidation; Human intestine microsomes; Human liver microsomes; UGT1A1

Indexed keywords

ANTINEOPLASTIC AGENT; GLUCURONOSYLTRANSFERASE; ISOENZYME; OBLONGIFOLIN C; UNCLASSIFIED DRUG; GLUCURONIDE; RECOMBINANT PROTEIN; SILIBININ; SILYMARIN; TERPENE;

EID: 84937879060     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2015.1004205     Document Type: Article
Times cited : (6)

References (32)
  • 1
    • 10744223995 scopus 로고    scopus 로고
    • Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid
    • Antoniou T, Gough K, Yoong D, Arbess G. (2004). Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid. Clin Infect Dis 38:e38-40.
    • (2004) Clin Infect Dis , vol.38 , pp. e38-40
    • Antoniou, T.1    Gough, K.2    Yoong, D.3    Arbess, G.4
  • 2
    • 77953762477 scopus 로고    scopus 로고
    • Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4
    • Aprile S, Del Grosso E, Grosa G. (2010). Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4. Drug Metab Dispos 38:1141-6.
    • (2010) Drug Metab Dispos , vol.38 , pp. 1141-1146
    • Aprile, S.1    Del Grosso, E.2    Grosa, G.3
  • 3
    • 0042858542 scopus 로고    scopus 로고
    • Evaluation of 30-azido-30-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: Specificity and influence of the UGT2B7∗2 polymorphism
    • Court MH, Krishnaswamy S, Hao Q, et al. (2003). Evaluation of 30-azido-30-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7∗2 polymorphism. Drug Metab Dispos 31:1125-33.
    • (2003) Drug Metab Dispos , vol.31 , pp. 1125-1133
    • Court, M.H.1    Krishnaswamy, S.2    Hao, Q.3
  • 4
    • 0041381056 scopus 로고    scopus 로고
    • UGT pharmacogenomics: Implications for cancer risk and cancer therapeutics
    • Desai AA, Innocenti F, Ratain MJ. (2003). UGT pharmacogenomics: implications for cancer risk and cancer therapeutics. Pharmacogenetics 13:517-23.
    • (2003) Pharmacogenetics , vol.13 , pp. 517-523
    • Desai, A.A.1    Innocenti, F.2    Ratain, M.J.3
  • 5
    • 18844387928 scopus 로고    scopus 로고
    • Determination of drug glucuronidation and UDP-glucuronosyltransferase selectivity using a 96-well radiometric assay
    • Di Marco A, D'Antoni M, Attaccalite S, et al. (2005). Determination of drug glucuronidation and UDP-glucuronosyltransferase selectivity using a 96-well radiometric assay. Drug Metab Dispos 33: 812-19.
    • (2005) Drug Metab Dispos , vol.33 , pp. 812-819
    • Di Marco, A.1    D'antoni, M.2    Attaccalite, S.3
  • 6
    • 84864117228 scopus 로고    scopus 로고
    • A new anticancer compound, oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through Bax activation
    • Feng C, Zhou LY, Yu T, et al. (2012). A new anticancer compound, oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through Bax activation. Int J Cancer 131:1445-54.
    • (2012) Int J Cancer , vol.131 , pp. 1445-1454
    • Feng, C.1    Zhou, L.Y.2    Yu, T.3
  • 7
    • 0035209568 scopus 로고    scopus 로고
    • The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism
    • Fisher MB, Paine MF, Strelevitz TJ, Wrighton SA. (2001). The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism. Drug Metab Rev 33:273-97.
    • (2001) Drug Metab Rev , vol.33 , pp. 273-297
    • Fisher, M.B.1    Paine, M.F.2    Strelevitz, T.J.3    Wrighton, S.A.4
  • 8
    • 38749138848 scopus 로고    scopus 로고
    • Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates
    • Fujiwara R, Nakajima M, Yamanaka H, et al. (2008). Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates. Drug Metab Dispos 36: 361-7.
    • (2008) Drug Metab Dispos , vol.36 , pp. 361-367
    • Fujiwara, R.1    Nakajima, M.2    Yamanaka, H.3
  • 9
    • 33745804475 scopus 로고    scopus 로고
    • Oblongifolins AD, polyprenylated benzoylphloroglucinol derivatives from Garcinia oblongifolia
    • Hamed W, Brajeul S, Mahuteau-Betzer F, et al. (2006). Oblongifolins AD, polyprenylated benzoylphloroglucinol derivatives from Garcinia oblongifolia. J Nat Prod 69:774-7.
    • (2006) J Nat Prod , vol.69 , pp. 774-777
    • Hamed, W.1    Brajeul, S.2    Mahuteau-Betzer, F.3
  • 10
    • 33947383703 scopus 로고    scopus 로고
    • Adverse events caused by drug interactions involving glucuronoconjugates of zidovudine, valproic acid and lamotrigine, and analysis of how such potential events are discussed in package inserts of Japan, UK and USA
    • Hirata-Koizumi M, Saito M, Miyake S, Hasegawa R. (2007). Adverse events caused by drug interactions involving glucuronoconjugates of zidovudine, valproic acid and lamotrigine, and analysis of how such potential events are discussed in package inserts of Japan, UK and USA. J Clin Pharm Ther 32:177-85.
    • (2007) J Clin Pharm Ther , vol.32 , pp. 177-185
    • Hirata-Koizumi, M.1    Saito, M.2    Miyake, S.3    Hasegawa, R.4
  • 11
    • 60549089249 scopus 로고    scopus 로고
    • Bioassay-guided isolation of xanthones and polycyclic prenylated acylphloroglucinols from Garcinia oblongifolia
    • Huang SX, Feng C, Zhou Y, et al. (2009). Bioassay-guided isolation of xanthones and polycyclic prenylated acylphloroglucinols from Garcinia oblongifolia. J Nat Prod 72:130-5.
    • (2009) J Nat Prod , vol.72 , pp. 130-135
    • Huang, S.X.1    Feng, C.2    Zhou, Y.3
  • 12
    • 0036266936 scopus 로고    scopus 로고
    • Characterization of raloxifene glucuronidation in vitro: Contribution of intestinal metabolism to presystemic clearance
    • Kemp DC, Fan PW, Stevens JC. (2002). Characterization of raloxifene glucuronidation in vitro: contribution of intestinal metabolism to presystemic clearance. Drug Metab Dispos 30:694-700.
    • (2002) Drug Metab Dispos , vol.30 , pp. 694-700
    • Kemp, D.C.1    Fan, P.W.2    Stevens, J.C.3
  • 13
    • 24044504415 scopus 로고    scopus 로고
    • Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes
    • Kostrubsky SE, Sinclair JF, Strom SC, et al. (2005). Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes. Toxicol Sci 87:146-55.
    • (2005) Toxicol Sci , vol.87 , pp. 146-155
    • Kostrubsky, S.E.1    Sinclair, J.F.2    Strom, S.C.3
  • 14
    • 0037324354 scopus 로고    scopus 로고
    • Serotonin (5-hydroxytryptamine) glucuronidation in vitro: Assay development, human liver microsome activities and species differences
    • Krishnaswamy S, Duan SX, Von Moltke LL, et al. (2003). Serotonin (5-hydroxytryptamine) glucuronidation in vitro: assay development, human liver microsome activities and species differences. Xenobiotica 33:169-80.
    • (2003) Xenobiotica , vol.33 , pp. 169-180
    • Krishnaswamy, S.1    Duan, S.X.2    Von Moltke, L.L.3
  • 15
    • 84899741515 scopus 로고    scopus 로고
    • The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation
    • Lao Y, Wan G, Liu Z, et al. (2014). The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation. Autophagy 10:736-49.
    • (2014) Autophagy , vol.10 , pp. 736-749
    • Lao, Y.1    Wan, G.2    Liu, Z.3
  • 16
    • 73149090339 scopus 로고    scopus 로고
    • Comparison of the drug-drug interactions potential of erlotinib and gefitinib via inhibition of UDP-glucuronosyltransferases
    • Liu Y, Ramirez J, House L, Ratain MJ. (2010). Comparison of the drug-drug interactions potential of erlotinib and gefitinib via inhibition of UDP-glucuronosyltransferases. Drug Metab Dispos 38:32-9.
    • (2010) Drug Metab Dispos , vol.38 , pp. 32-39
    • Liu, Y.1    Ramirez, J.2    House, L.3    Ratain, M.J.4
  • 17
    • 84888246372 scopus 로고    scopus 로고
    • A new biphenyl and other constituents from the wood of Garcinia schomburgkiana
    • Mungmee C, Sitthigool S, Buakeaw A, Suttisri R. (2013). A new biphenyl and other constituents from the wood of Garcinia schomburgkiana. Nat Prod Res 27:1949-55.
    • (2013) Nat Prod Res , vol.27 , pp. 1949-1955
    • Mungmee, C.1    Sitthigool, S.2    Buakeaw, A.3    Suttisri, R.4
  • 18
    • 58149467072 scopus 로고    scopus 로고
    • Determination of mRNA expression of human UDP-glucuronosyltransferases and application for localization in various human tissues by real-time reverse transcriptase-polymerase chain reaction
    • Ohno S, Nakajin S. (2009). Determination of mRNA expression of human UDP-glucuronosyltransferases and application for localization in various human tissues by real-time reverse transcriptase-polymerase chain reaction. Drug Metab Dispos 37:32-40.
    • (2009) Drug Metab Dispos , vol.37 , pp. 32-40
    • Ohno, S.1    Nakajin, S.2
  • 19
    • 0032707765 scopus 로고    scopus 로고
    • Structural and functional studies of UDP-glucuronosyltransferases
    • Radominska-Pandya A, Czernik PJ, Little JM, et al. (1999). Structural and functional studies of UDP-glucuronosyltransferases. Drug Metab Rev 31:817-99.
    • (1999) Drug Metab Rev , vol.31 , pp. 817-899
    • Radominska-Pandya, A.1    Czernik, P.J.2    Little, J.M.3
  • 20
    • 84875924213 scopus 로고    scopus 로고
    • The UDP-glucuronosyltransferases: Their role in drug metabolism and detoxification
    • Rowland A, Miners JO, Mackenzie PI. (2013). The UDP-glucuronosyltransferases: their role in drug metabolism and detoxification. Int J Biochem Cell Biol 45:1121-32.
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 1121-1132
    • Rowland, A.1    Miners, J.O.2    Mackenzie, P.I.3
  • 21
    • 84908615755 scopus 로고    scopus 로고
    • Validated assay for the evaluation of multiple glucuronidation activities in human liver microsomes via liquid chromatography-tandem mass spectrometry
    • Shi R, Yang YY, Zhong J, et al. (2014). Validated assay for the evaluation of multiple glucuronidation activities in human liver microsomes via liquid chromatography-tandem mass spectrometry. RSC Adv 4:56132-8.
    • (2014) RSC Adv , vol.4 , pp. 56132-56138
    • Shi, R.1    Yang, Y.Y.2    Zhong, J.3
  • 22
    • 84866375395 scopus 로고    scopus 로고
    • Comparison of the cytotoxic effects of enantiopure PPAPs, including nemorosone and clusianone
    • Simpkins NS, Holtrup F, Rodeschini V, et al. (2012). Comparison of the cytotoxic effects of enantiopure PPAPs, including nemorosone and clusianone. Bioorg Med Chem Lett 22:6144-7.
    • (2012) Bioorg Med Chem Lett , vol.22 , pp. 6144-6147
    • Simpkins, N.S.1    Holtrup, F.2    Rodeschini, V.3
  • 23
    • 2442649042 scopus 로고    scopus 로고
    • Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases
    • Sridar C, Goosen TC, Kent UM, et al. (2004). Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases. Drug Metab Dispos 32: 587-94.
    • (2004) Drug Metab Dispos , vol.32 , pp. 587-594
    • Sridar, C.1    Goosen, T.C.2    Kent, U.M.3
  • 25
    • 36349019788 scopus 로고    scopus 로고
    • In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases
    • Tong Z, Li H, Goljer I, et al. (2007). In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos 35: 2203-10.
    • (2007) Drug Metab Dispos , vol.35 , pp. 2203-2210
    • Tong, Z.1    Li, H.2    Goljer, I.3
  • 26
    • 0034128936 scopus 로고    scopus 로고
    • Human UDP-glucuronosyltransferases: Metabolism, expression, and disease
    • Tukey RH, Strassburg CP. (2000). Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annu Rev Pharmacol Toxicol 40:581-616.
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 581-616
    • Tukey, R.H.1    Strassburg, C.P.2
  • 27
    • 33344473930 scopus 로고    scopus 로고
    • Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) "probes" for human UDP-glucuronosyltransferases
    • Uchaipichat V, Mackenzie PI, Elliot DJ, Miners JO. (2006). Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) "probes" for human UDP-glucuronosyltransferases. Drug Metab Dispos 34:449-56.
    • (2006) Drug Metab Dispos , vol.34 , pp. 449-456
    • Uchaipichat, V.1    Mackenzie, P.I.2    Elliot, D.J.3    Miners, J.O.4
  • 28
    • 1842536833 scopus 로고    scopus 로고
    • Human UDPglucuronosyltransferases: Isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid
    • Uchaipichat V, Mackenzie PI, Guo XH, et al. (2004). Human UDPglucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid. Drug Metab Dispos 32:413-23.
    • (2004) Drug Metab Dispos , vol.32 , pp. 413-423
    • Uchaipichat, V.1    Mackenzie, P.I.2    Guo, X.H.3
  • 29
    • 84859899415 scopus 로고    scopus 로고
    • Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: Altered alamethicin concentration and utility to screen for UGT inhibitors
    • Walsky RL, Bauman JN, Bourcier K, et al. (2012). Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors. Drug Metab Dispos 40:1051-65.
    • (2012) Drug Metab Dispos , vol.40 , pp. 1051-1065
    • Walsky, R.L.1    Bauman, J.N.2    Bourcier, K.3
  • 30
    • 84884328877 scopus 로고    scopus 로고
    • Absolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities
    • Xu B, Gao S, Wu B, et al. (2014). Absolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities. J Pharm Biomed Anal 88:180-90.
    • (2014) J Pharm Biomed Anal , vol.88 , pp. 180-190
    • Xu, B.1    Gao, S.2    Wu, B.3
  • 31
    • 58949100336 scopus 로고    scopus 로고
    • Bioassay and ultraperformance liquid chromatography/mass spectrometry guided isolation of apoptosis-inducing benzophenones and xanthone from the pericarp of Garcinia yunnanensis Hu
    • Xu G, Feng C, Zhou Y, et al. (2008). Bioassay and ultraperformance liquid chromatography/mass spectrometry guided isolation of apoptosis-inducing benzophenones and xanthone from the pericarp of Garcinia yunnanensis Hu. J Agric Food Chem 56:11144-50.
    • (2008) J Agric Food Chem , vol.56 , pp. 11144-11150
    • Xu, G.1    Feng, C.2    Zhou, Y.3
  • 32
    • 77749268050 scopus 로고    scopus 로고
    • Cytotoxic acylphloroglucinol derivatives from the twigs of Garcinia cowa
    • Xu G, Kan WL, Zhou Y, et al. (2010). Cytotoxic acylphloroglucinol derivatives from the twigs of Garcinia cowa. J Nat Prod 73:104-8.
    • (2010) J Nat Prod , vol.73 , pp. 104-108
    • Xu, G.1    Kan, W.L.2    Zhou, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.