Isoflurane induced cognitive impairment in aged rats through hippocampal calcineurin/NFAT signaling

Biochemical and Biophysical Research Communications

Volumn 460, Issue 4, 2015, Pages 889-895

  Ni, Cheng ^a   Li, Zhengqian ^a   Qian, Min ^a   Zhou, Yang ^a   Wang, Jun ^a   Guo, Xiangyang ^a  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

Calcineurin; Cognitive impairment; Cyclosporine A; Isoflurane; Nuclear factor of activated T cells

Indexed keywords

CALCINEURIN; ISOFLURANE; TRANSCRIPTION FACTOR NFAT;

AGING; ANIMAL; CHEMICALLY INDUCED; COGNITIVE DEFECT; DRUG EFFECTS; HIPPOCAMPUS; MALE; METABOLISM; PSYCHOLOGY; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

AGING; ANIMALS; CALCINEURIN; COGNITION DISORDERS; HIPPOCAMPUS; ISOFLURANE; MALE; NFATC TRANSCRIPTION FACTORS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 84937764179     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.03.083     Document Type: Article

References (41)

1. W. Morishita, H. Marie, and R.C. Malenka Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses Nat. Neurosci. 8 2005 1043 1050
2. A. Shalizi, et al. A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation Science 311 2006 1012 1017
3. I.A. Graef, et al. Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons Cell 113 2003 657 670
4. R.D. Groth, and P.G. Mermelstein Brain-derived neurotrophic factor activation of NFAT (nuclear factor of activated T-cells)-dependent transcription: a role for the transcription factor NFATc4 in neurotrophin-mediated gene expression J. Neurosci. 23 2003 8125 8134 the official Journal of Society for Neuroscience
5. A. Freeman, A. Franciscovich, M. Bowers, D.J. Sandstrom, and S. Sanyal NFAT regulates pre-synaptic development and activity-dependent plasticity in Drosophila Mol. Cell. Neurosci. 46 2011 535 547
6. H.M. Abdul, J.L. Furman, M.A. Sama, D.M. Mathis, and C.M. Norris NFATs and Alzheimer's disease Mol. Cell. Pharmacol. 2 2010 7 14
7. L.C. Reese, W. Zhang, K.T. Dineley, R. Kayed, and G. Taglialatela Selective induction of calcineurin activity and signaling by oligomeric amyloid beta Aging Cell 7 2008 824 835
8. C.M. Norris, et al. Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models J. Neurosci. 25 2005 4649 4658 the official Journal of Society for Neuroscience
9. H.G. Wang, et al. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD Science 284 1999 339 343
10. K.T. Dineley, D. Hogan, W.R. Zhang, and G. Taglialatela Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice Neurobiol. Learn. Mem. 88 2007 217 224
11. K.A. Hartholt, T.J. van der Cammen, and M. Klimek Postoperative cognitive dysfunction in geriatric patients Z. fur Gerontol. Geriatr. 45 2012 411 416
12. A.Y. Bekker, and E.J. Weeks Cognitive function after anaesthesia in the elderly Best Pract. Res. Clin. Anaesthesiol. 17 2003 259 272
13. J. Steinmetz, et al. Long-term consequences of postoperative cognitive dysfunction Anesthesiology 110 2009 548 555
14. Z. Xie, et al. The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo Ann. Neurol. 64 2008 618 627
15. H. Yang, et al. Inhalational anesthetics induce cell damage by disruption of intracellular calcium homeostasis with different potencies Anesthesiology 109 2008 243 250
16. D. Lindholm, H. Wootz, and L. Korhonen ER stress and neurodegenerative diseases Cell Death Differ. 13 2006 385 392
17. Y. Zhang, et al. The mitochondrial pathway of anesthetic isoflurane-induced apoptosis J. Biol. Chem. 285 2010 4025 4037
18. Z. Assefa, et al. Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis J. Biol. Chem. 279 2004 43227 43236
19. X. Wu, et al. Opposing roles for calcineurin and ATF3 in squamous skin cancer Nature 465 2010 368 372
20. C. Ni, et al. Melatonin premedication attenuates isoflurane anesthesia-induced beta-amyloid generation and cholinergic dysfunction in the hippocampus of aged rats Int. J. Neurosci. 123 2013 213 220
21. J.R. Whitlock, A.J. Heynen, M.G. Shuler, and M.F. Bear Learning induces long-term potentiation in the hippocampus Science 313 2006 1093 1097
22. M.M. Osman, et al. Cyclosporine-A as a neuroprotective agent against stroke: its translation from laboratory research to clinical application Neuropeptides 45 2011 359 368
23. L.C. Reese, and G. Taglialatela A role for calcineurin in Alzheimer's disease Curr. Neuropharmacol. 9 2011 685 692
24. I.M. Mansuy, M. Mayford, B. Jacob, E.R. Kandel, and M.E. Bach Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory Cell 92 1998 39 49
25. Y. Yang, et al. Reversible blockade of experience-dependent plasticity by calcineurin in mouse visual cortex Nat. Neurosci. 8 2005 791 796
26. G. Malleret, et al. Inducible and reversible enhancement of learning, memory, and long-term potentiation by genetic inhibition of calcineurin Cell 104 2001 675 686
27. J.H. Wang, and P.T. Kelly The balance between postsynaptic Ca(2+)-dependent protein kinase and phosphatase activities controlling synaptic strength Learn. Mem. 3 1996 170 181
28. Y.M. Lu, I.M. Mansuy, E.R. Kandel, and J. Roder Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP Neuron 26 2000 197 205
29. H. Okamura, et al. A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1 Mol. Cell. Biol. 24 2004 4184 4195
30. N. Schwartz, A. Schohl, and E.S. Ruthazer Neural activity regulates synaptic properties and dendritic structure in vivo through calcineurin/NFAT signaling Neuron 62 2009 655 669
31. I.A. Graef, et al. L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons Nature 401 1999 703 708
32. H.M. Abdul, et al. Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling J. Neurosci. 29 2009 12957 12969 the official Journal of Society for Neuroscience
33. J.D. Ulrich, et al. Distinct activation properties of the nuclear factor of activated T-cells (NFAT) isoforms NFATc3 and NFATc4 in neurons J. Biol. Chem. 287 2012 37594 37609
34. D. Lin, G. Li, and Z. Zuo Volatile anesthetic post-treatment induces protection via inhibition of glycogen synthase kinase 3beta in human neuron-like cells Neuroscience 179 2011 73 79
35. D. Tedesco, and L. Haragsim Cyclosporine: a review J. Transplant. 2012 2012 230386
36. H. Uchino, et al. Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat Brain Res. 812 1998 216 226
37. Y. Cao, et al. Isoflurane anesthesia results in reversible ultrastructure and occludin tight junction protein expression changes in hippocampal blood-brain barrier in aged rats Neurosci. Lett. 587C 2014 51 56
38. Z.Q. Li, et al. Activation of the canonical nuclear factor-kappaB pathway is involved in isoflurane-induced hippocampal interleukin-1beta elevation and the resultant cognitive deficits in aged rats Biochem. Biophys. Res. Commun. 438 2013 628 634
39. L. Cao, L. Li, D. Lin, and Z. Zuo Isoflurane induces learning impairment that is mediated by interleukin 1beta in rodents PloS one 7 2012 e51431
40. G. Taglialatela, D. Hogan, W.R. Zhang, and K.T. Dineley Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition Behav. Brain Res. 200 2009 95 99
41. H. Fukumoto, B.S. Cheung, B.T. Hyman, and M.C. Irizarry Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease Arch. Neurol. 59 2002 1381 1389