Activation of the canonical nuclear factor-κB pathway is involved in isoflurane-induced hippocampal interleukin-1β elevation and the resultant cognitive deficits in aged rats

Biochemical and Biophysical Research Communications

Volumn 438, Issue 4, 2013, Pages 628-634

  Li, Zheng Qian ^a   Rong, Xiao Ying ^a   Liu, Ya Jie ^a   Ni, Cheng ^a   Tian, Xiao Sheng ^b   Mo, Na ^c   Chui, De Hua ^b   Guo, Xiang Yang ^a  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c CANCER HOSPITAL   (China)

Author keywords

Interleukin 1 ; Isoflurane; NF B; Postoperative cognitive dysfunction

Indexed keywords

I KAPPA B; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; ISOFLURANE; PYRROLIDINE DITHIOCARBAMATE; TRANSCRIPTION FACTOR RELA;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EXPOSURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; INTRACELLULAR SIGNALING; MALE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; REDUCTION KINETICS;

INTERLEUKIN-1Β; ISOFLURANE; NF-ΚB; POSTOPERATIVE COGNITIVE DYSFUNCTION;

AGING; ANESTHETICS, INHALATION; ANIMALS; COGNITION; HIPPOCAMPUS; INTERLEUKIN-1BETA; ISOFLURANE; MALE; NEUROGLIA; NF-KAPPA B; PHOSPHORYLATION; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; THIOCARBAMATES; UP-REGULATION;

RATTUS;

EID: 84883306232     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.08.003     Document Type: Article

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