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Volumn 89, Issue 15, 2015, Pages 7813-7828

Inhibitory effect of individual or combinations of broadly neutralizing antibodies and antiviral reagents against cell-free and cell-to-cell HIV-1 transmission

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; LUCIFERASE; NEUTRALIZING ANTIBODY; ANTIVIRUS AGENT; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY;

EID: 84937701915     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00783-15     Document Type: Article
Times cited : (35)

References (81)
  • 1
    • 77949384495 scopus 로고    scopus 로고
    • Immunology and the elusive AIDS vaccine
    • Virgin HW, Walker BD. 2010. Immunology and the elusive AIDS vaccine. Nature 464:224-231. http://dx.doi.org/10.1038/nature08898.
    • (2010) Nature , vol.464 , pp. 224-231
    • Virgin, H.W.1    Walker, B.D.2
  • 2
    • 0020634248 scopus 로고
    • "Trojan Horse" leukocytes in AIDS
    • Anderson DJ, Yunis EJ. 1983. "Trojan Horse" leukocytes in AIDS. N Engl J Med 309:984-985.
    • (1983) N Engl J Med , vol.309 , pp. 984-985
    • Anderson, D.J.1    Yunis, E.J.2
  • 6
    • 84867847173 scopus 로고    scopus 로고
    • T cell virological synapses and HIV-1 pathogenesis
    • Chen BK. 2012. T cell virological synapses and HIV-1 pathogenesis. Immunol Res 54:133-139. http://dx.doi.org/10.1007/s12026-012-8320-8.
    • (2012) Immunol Res , vol.54 , pp. 133-139
    • Chen, B.K.1
  • 7
    • 85047690554 scopus 로고    scopus 로고
    • Dangerous liaisons at the virological synapse
    • Piguet V, Sattentau Q. 2004. Dangerous liaisons at the virological synapse. J Clin Invest 114:605-610. http://dx.doi.org/10.1172/JCI22812.
    • (2004) J Clin Invest , vol.114 , pp. 605-610
    • Piguet, V.1    Sattentau, Q.2
  • 8
    • 54149119141 scopus 로고    scopus 로고
    • Avoiding the void: cell-to-cell spread of human viruses
    • Sattentau Q. 2008. Avoiding the void: cell-to-cell spread of human viruses. Nat Rev Microbiol 6:815-826. http://dx.doi.org/10.1038/nrmicro1972.
    • (2008) Nat Rev Microbiol , vol.6 , pp. 815-826
    • Sattentau, Q.1
  • 10
    • 84861205063 scopus 로고    scopus 로고
    • Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies
    • Abela IA, Berlinger L, Schanz M, Reynell L, Gunthard HF, Rusert P, Trkola A. 2012. Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies. PLoS Pathog 8:e1002634. http://dx.doi.org/10.1371/journal.ppat.1002634.
    • (2012) PLoS Pathog , vol.8
    • Abela, I.A.1    Berlinger, L.2    Schanz, M.3    Reynell, L.4    Gunthard, H.F.5    Rusert, P.6    Trkola, A.7
  • 11
    • 80052395837 scopus 로고    scopus 로고
    • Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy
    • Sigal A, Kim JT, Balazs AB, Dekel E, Mayo A, Milo R, Baltimore D. 2011. Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy. Nature 477:95-98. http://dx.doi.org/10.1038/nature10347.
    • (2011) Nature , vol.477 , pp. 95-98
    • Sigal, A.1    Kim, J.T.2    Balazs, A.B.3    Dekel, E.4    Mayo, A.5    Milo, R.6    Baltimore, D.7
  • 12
    • 84887618532 scopus 로고    scopus 로고
    • Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies
    • Schiffner T, Sattentau QJ, Duncan CJ. 2013. Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies. Vaccine 31:5789-5797. http://dx.doi.org/10.1016/j.vaccine.2013.10.020.
    • (2013) Vaccine , vol.31 , pp. 5789-5797
    • Schiffner, T.1    Sattentau, Q.J.2    Duncan, C.J.3
  • 13
    • 36049037370 scopus 로고    scopus 로고
    • Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses
    • Chen P, Hubner W, Spinelli MA, Chen BK. 2007. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. J Virol 81:12582-12595. http://dx.doi.org/10.1128/JVI.00381-07.
    • (2007) J Virol , vol.81 , pp. 12582-12595
    • Chen, P.1    Hubner, W.2    Spinelli, M.A.3    Chen, B.K.4
  • 14
    • 0032839482 scopus 로고    scopus 로고
    • Antiretroviral-drug concentrations in semen: implications for sexual transmission of human immunodeficiency virus type 1
    • Kashuba AD, Dyer JR, Kramer LM, Raasch RH, Eron JJ, Cohen MS. 1999. Antiretroviral-drug concentrations in semen: implications for sexual transmission of human immunodeficiency virus type 1. Antimicrob Agents Chemother 43:1817-1826.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1817-1826
    • Kashuba, A.D.1    Dyer, J.R.2    Kramer, L.M.3    Raasch, R.H.4    Eron, J.J.5    Cohen, M.S.6
  • 15
    • 0034660318 scopus 로고    scopus 로고
    • Minimization of chronic plasma viremia in rhesus macaques immunized with synthetic HIV-1 Tat peptides and infected with a chimeric simian/human immunodeficiency virus (SHIV33)
    • Goldstein G, Manson K, Tribbick G, Smith R. 2000. Minimization of chronic plasma viremia in rhesus macaques immunized with synthetic HIV-1 Tat peptides and infected with a chimeric simian/human immunodeficiency virus (SHIV33). Vaccine 18:2789-2795. http://dx.doi.org/10.1016/S0264-410X(00)00085-2.
    • (2000) Vaccine , vol.18 , pp. 2789-2795
    • Goldstein, G.1    Manson, K.2    Tribbick, G.3    Smith, R.4
  • 16
    • 79960409830 scopus 로고    scopus 로고
    • Multiploid inheritance of HIV-1 during cell-to-cell infection
    • Del Portillo A, Tripodi J, Najfeld V, Wodarz D, Levy DN, Chen BK. 2011. Multiploid inheritance of HIV-1 during cell-to-cell infection. J Virol 85:7169-7176. http://dx.doi.org/10.1128/JVI.00231-11.
    • (2011) J Virol , vol.85 , pp. 7169-7176
    • Del Portillo, A.1    Tripodi, J.2    Najfeld, V.3    Wodarz, D.4    Levy, D.N.5    Chen, B.K.6
  • 19
    • 84864292056 scopus 로고    scopus 로고
    • Microbicides: still a long road to success
    • Vanpouille C, Arakelyan A, Margolis L. 2012. Microbicides: still a long road to success. Trends Microbiol 20:369-375. http://dx.doi.org/10.1016/j.tim.2012.05.005.
    • (2012) Trends Microbiol , vol.20 , pp. 369-375
    • Vanpouille, C.1    Arakelyan, A.2    Margolis, L.3
  • 20
    • 78649436881 scopus 로고    scopus 로고
    • Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets
    • Garg S, Goldman D, Krumme M, Rohan LC, Smoot S, Friend DR. 2010. Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets. Antiviral Res 88(Suppl 1):S19-S29. http://dx.doi.org/10.1016/j.antiviral.2010.09.010.
    • (2010) Antiviral Res , vol.88 , pp. S19-S29
    • Garg, S.1    Goldman, D.2    Krumme, M.3    Rohan, L.C.4    Smoot, S.5    Friend, D.R.6
  • 21
    • 2342531101 scopus 로고    scopus 로고
    • Antiviral drugs in current clinical use
    • De Clercq E. 2004. Antiviral drugs in current clinical use. J Clin Virol 30:115-133. http://dx.doi.org/10.1016/j.jcv.2004.02.009.
    • (2004) J Clin Virol , vol.30 , pp. 115-133
    • De Clercq, E.1
  • 22
    • 84857132880 scopus 로고    scopus 로고
    • Combination of antiretroviral drugs as microbicides
    • Balzarini J, Schols D. 2012. Combination of antiretroviral drugs as microbicides. Curr HIV Res 10:53-60. http://dx.doi.org/10.2174/157016212799304652.
    • (2012) Curr HIV Res , vol.10 , pp. 53-60
    • Balzarini, J.1    Schols, D.2
  • 24
    • 0032565098 scopus 로고    scopus 로고
    • A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients: the INCAS Trial. Italy, The Netherlands, Canada and Australia Study
    • Montaner JS, Reiss P, Cooper D, Vella S, Harris M, Conway B, Wainberg MA, Smith D, Robinson P, Hall D, Myers M, Lange JM. 1998. A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients: the INCAS Trial. Italy, The Netherlands, Canada and Australia Study. JAMA 279:930-937.
    • (1998) JAMA , vol.279 , pp. 930-937
    • Montaner, J.S.1    Reiss, P.2    Cooper, D.3    Vella, S.4    Harris, M.5    Conway, B.6    Wainberg, M.A.7    Smith, D.8    Robinson, P.9    Hall, D.10    Myers, M.11    Lange, J.M.12
  • 26
    • 0030835875 scopus 로고    scopus 로고
    • Hepatitis B: diagnosis, prevention, and treatment
    • Gitlin N. 1997. Hepatitis B: diagnosis, prevention, and treatment. Clin Chem 43:1500-1506.
    • (1997) Clin Chem , vol.43 , pp. 1500-1506
    • Gitlin, N.1
  • 27
    • 77953543379 scopus 로고    scopus 로고
    • Rational antibody-based HIV-1 vaccine design: current approaches and future directions
    • Walker LM, Burton DR. 2010. Rational antibody-based HIV-1 vaccine design: current approaches and future directions. Curr Opin Immunol 22:358-366. http://dx.doi.org/10.1016/j.coi.2010.02.012.
    • (2010) Curr Opin Immunol , vol.22 , pp. 358-366
    • Walker, L.M.1    Burton, D.R.2
  • 28
    • 84860759632 scopus 로고    scopus 로고
    • B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study
    • Haynes BF, Kelsoe G, Harrison SC, Kepler TB. 2012. B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nat Biotechnol 30:423-433. http://dx.doi.org/10.1038/nbt.2197.
    • (2012) Nat Biotechnol , vol.30 , pp. 423-433
    • Haynes, B.F.1    Kelsoe, G.2    Harrison, S.C.3    Kepler, T.B.4
  • 33
    • 45849125030 scopus 로고    scopus 로고
    • Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays
    • Chapter 12, Unit 12.11
    • Montefiori DC. 2005. Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays. Curr Protoc Immunol Chapter 12:Unit 12.11. http://dx.doi.org/10.1002/0471142735.im1211s64.
    • (2005) Curr Protoc Immunol
    • Montefiori, D.C.1
  • 36
    • 84856398863 scopus 로고    scopus 로고
    • International technology transfer of a GCLP-compliant HIV-1 neutralizing antibody assay for human clinical trials
    • Ozaki DA, Gao H, Todd CA, Greene KM, Montefiori DC, Sarzotti-Kelsoe M. 2012. International technology transfer of a GCLP-compliant HIV-1 neutralizing antibody assay for human clinical trials. PLoS One 7:e30963. http://dx.doi.org/10.1371/journal.pone.0030963.
    • (2012) PLoS One , vol.7
    • Ozaki, D.A.1    Gao, H.2    Todd, C.A.3    Greene, K.M.4    Montefiori, D.C.5    Sarzotti-Kelsoe, M.6
  • 40
    • 43249120051 scopus 로고    scopus 로고
    • Cross-clade neutralization patterns among HIV-1 strains from the six major clades of the pandemic evaluated and compared in two different models
    • Brown BK, Wieczorek L, Sanders-Buell E, Rosa Borges A, Robb ML, Birx DL, Michael NL, McCutchan FE, Polonis VR. 2008. Cross-clade neutralization patterns among HIV-1 strains from the six major clades of the pandemic evaluated and compared in two different models. Virology 375:529-538. http://dx.doi.org/10.1016/j.virol.2008.02.022.
    • (2008) Virology , vol.375 , pp. 529-538
    • Brown, B.K.1    Wieczorek, L.2    Sanders-Buell, E.3    Rosa Borges, A.4    Robb, M.L.5    Birx, D.L.6    Michael, N.L.7    McCutchan, F.E.8    Polonis, V.R.9
  • 43
    • 78650798812 scopus 로고    scopus 로고
    • Uterine epithelial cell regulation of DC-SIGN expression inhibits transmitted/founder HIV-1 trans infection by immature dendritic cells
    • Ochiel DO, Ochsenbauer C, Kappes JC, Ghosh M, Fahey JV, Wira CR. 2010. Uterine epithelial cell regulation of DC-SIGN expression inhibits transmitted/founder HIV-1 trans infection by immature dendritic cells. PLoS One 5:e14306. http://dx.doi.org/10.1371/journal.pone.0014306.
    • (2010) PLoS One , vol.5
    • Ochiel, D.O.1    Ochsenbauer, C.2    Kappes, J.C.3    Ghosh, M.4    Fahey, J.V.5    Wira, C.R.6
  • 45
    • 3142679567 scopus 로고    scopus 로고
    • Intrinsic obstacles to human immunodeficiency virus type 1 coreceptor switching
    • Pastore C, Ramos A, Mosier DE. 2004. Intrinsic obstacles to human immunodeficiency virus type 1 coreceptor switching. J Virol 78:7565-7574. http://dx.doi.org/10.1128/JVI.78.14.7565-7574.2004.
    • (2004) J Virol , vol.78 , pp. 7565-7574
    • Pastore, C.1    Ramos, A.2    Mosier, D.E.3
  • 46
    • 1642447695 scopus 로고    scopus 로고
    • Dynamics of HIV-1 recombination in its natural target cells
    • Levy DN, Aldrovandi GM, Kutsch O, Shaw GM. 2004. Dynamics of HIV-1 recombination in its natural target cells. Proc Natl Acad Sci USA 101:4204-4209. http://dx.doi.org/10.1073/pnas.0306764101.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4204-4209
    • Levy, D.N.1    Aldrovandi, G.M.2    Kutsch, O.3    Shaw, G.M.4
  • 48
    • 0003126793 scopus 로고    scopus 로고
    • Neutralization of HIV-1 infection of human peripheral blood mononuclear cells (PBMC): infectivity reduction method
    • Mascola JR. 1999. Neutralization of HIV-1 infection of human peripheral blood mononuclear cells (PBMC): infectivity reduction method. Methods Mol Med 17:317-322.
    • (1999) Methods Mol Med , vol.17 , pp. 317-322
    • Mascola, J.R.1
  • 49
    • 79960342938 scopus 로고    scopus 로고
    • An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum
    • Ferrari G, Pollara J, Kozink D, Harms T, Drinker M, Freel S, Moody MA, Alam SM, Tomaras GD, Ochsenbauer C, Kappes JC, Shaw GM, Hoxie JA, Robinson JE, Haynes BF. 2011. An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum. J Virol 85:7029-7036. http://dx.doi.org/10.1128/JVI.00171-11.
    • (2011) J Virol , vol.85 , pp. 7029-7036
    • Ferrari, G.1    Pollara, J.2    Kozink, D.3    Harms, T.4    Drinker, M.5    Freel, S.6    Moody, M.A.7    Alam, S.M.8    Tomaras, G.D.9    Ochsenbauer, C.10    Kappes, J.C.11    Shaw, G.M.12    Hoxie, J.A.13    Robinson, J.E.14    Haynes, B.F.15
  • 51
    • 13844255333 scopus 로고    scopus 로고
    • Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusionassociated motif in gp41
    • Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA. 2005. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusionassociated motif in gp41. Immunity 22:163-173. http://dx.doi.org/10.1016/j.immuni.2004.12.011.
    • (2005) Immunity , vol.22 , pp. 163-173
    • Cardoso, R.M.1    Zwick, M.B.2    Stanfield, R.L.3    Kunert, R.4    Binley, J.M.5    Katinger, H.6    Burton, D.R.7    Wilson, I.A.8
  • 53
    • 84891680667 scopus 로고    scopus 로고
    • Mechanism of HIV-1 neutralization by antibodies targeting a membrane-proximal region of gp41
    • Chen J, Frey G, Peng H, Rits-Volloch S, Garrity J, Seaman MS, Chen B. 2014. Mechanism of HIV-1 neutralization by antibodies targeting a membrane-proximal region of gp41. J Virol 88:1249-1258. http://dx.doi.org/10.1128/JVI.02664-13.
    • (2014) J Virol , vol.88 , pp. 1249-1258
    • Chen, J.1    Frey, G.2    Peng, H.3    Rits-Volloch, S.4    Garrity, J.5    Seaman, M.S.6    Chen, B.7
  • 56
    • 84880627533 scopus 로고    scopus 로고
    • Emergence of gp120 V3 variants confers neutralization resistance in an R5 simian-human immunodeficiency virus-infected macaque elite neutralizer that targets the N332 glycan of the human immunodeficiency virus type 1 envelope glycoprotein
    • Sadjadpour R, Donau OK, Shingai M, Buckler-White A, Kao S, Strebel K, Nishimura Y, Martin MA. 2013. Emergence of gp120 V3 variants confers neutralization resistance in an R5 simian-human immunodeficiency virus-infected macaque elite neutralizer that targets the N332 glycan of the human immunodeficiency virus type 1 envelope glycoprotein. J Virol 87:8798-8804. http://dx.doi.org/10.1128/JVI.00878-13.
    • (2013) J Virol , vol.87 , pp. 8798-8804
    • Sadjadpour, R.1    Donau, O.K.2    Shingai, M.3    Buckler-White, A.4    Kao, S.5    Strebel, K.6    Nishimura, Y.7    Martin, M.A.8
  • 59
    • 0037006883 scopus 로고    scopus 로고
    • Development of anti-CD4 MAb hu5A8 for treatment of HIV-1 infection: preclinical assessment in non-human primates
    • Boon L, Holland B, Gordon W, Liu P, Shiau F, Shanahan W, Reimann KA, Fung M. 2002. Development of anti-CD4 MAb hu5A8 for treatment of HIV-1 infection: preclinical assessment in non-human primates. Toxicology 172:191-203. http://dx.doi.org/10.1016/S0300-483X(02)00002-1.
    • (2002) Toxicology , vol.172 , pp. 191-203
    • Boon, L.1    Holland, B.2    Gordon, W.3    Liu, P.4    Shiau, F.5    Shanahan, W.6    Reimann, K.A.7    Fung, M.8
  • 61
    • 77949412821 scopus 로고    scopus 로고
    • Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition
    • Martin N, Welsch S, Jolly C, Briggs JA, Vaux D, Sattentau QJ. 2010. Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition. J Virol 84:3516-3527. http://dx.doi.org/10.1128/JVI.02651-09.
    • (2010) J Virol , vol.84 , pp. 3516-3527
    • Martin, N.1    Welsch, S.2    Jolly, C.3    Briggs, J.A.4    Vaux, D.5    Sattentau, Q.J.6
  • 63
    • 0036306664 scopus 로고    scopus 로고
    • TAK-779, a nonpeptide CC chemokine receptor antagonist, protects the brain against focal cerebral ischemia in mice
    • Takami S, Minami M, Katayama T, Nagata I, Namura S, Satoh M. 2002. TAK-779, a nonpeptide CC chemokine receptor antagonist, protects the brain against focal cerebral ischemia in mice. J Cereb Blood Flow Metab 22:780-784. http://dx.doi.org/10.1097/00004647-200207000-00003.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 780-784
    • Takami, S.1    Minami, M.2    Katayama, T.3    Nagata, I.4    Namura, S.5    Satoh, M.6
  • 65
  • 68
    • 0002294347 scopus 로고
    • A simple sequentially rejective multiple test procedure
    • Holm S. 1979. A simple sequentially rejective multiple test procedure. Scand J Statist 6:65-70.
    • (1979) Scand J Statist , vol.6 , pp. 65-70
    • Holm, S.1
  • 73
    • 33846036832 scopus 로고    scopus 로고
    • Inefficient human immunodeficiency virus replication in mobile lymphocytes
    • Sourisseau M, Sol-Foulon N, Porrot F, Blanchet F, Schwartz O. 2007. Inefficient human immunodeficiency virus replication in mobile lymphocytes. J Virol 81:1000-1012. http://dx.doi.org/10.1128/JVI.01629-06.
    • (2007) J Virol , vol.81 , pp. 1000-1012
    • Sourisseau, M.1    Sol-Foulon, N.2    Porrot, F.3    Blanchet, F.4    Schwartz, O.5
  • 78
    • 84859044775 scopus 로고    scopus 로고
    • Transmembrane domain membrane proximal external region but not surface unit-directed broadly neutralizing HIV-1 antibodies can restrict dendritic cell-mediated HIV-1 trans-infection
    • Sagar M, Akiyama H, Etemad B, Ramirez N, Freitas I, Gummuluru S. 2012. Transmembrane domain membrane proximal external region but not surface unit-directed broadly neutralizing HIV-1 antibodies can restrict dendritic cell-mediated HIV-1 trans-infection. J Infect Dis 205: 1248-1257. http://dx.doi.org/10.1093/infdis/jis183.
    • (2012) J Infect Dis , vol.205 , pp. 1248-1257
    • Sagar, M.1    Akiyama, H.2    Etemad, B.3    Ramirez, N.4    Freitas, I.5    Gummuluru, S.6
  • 79
    • 0030986787 scopus 로고    scopus 로고
    • HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor
    • Bieniasz PD, Fridell RA, Aramori I, Ferguson SS, Caron MG, Cullen BR. 1997. HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor. EMBO J 16: 2599-2609. http://dx.doi.org/10.1093/emboj/16.10.2599.
    • (1997) EMBO J , vol.16 , pp. 2599-2609
    • Bieniasz, P.D.1    Fridell, R.A.2    Aramori, I.3    Ferguson, S.S.4    Caron, M.G.5    Cullen, B.R.6
  • 81
    • 80053440098 scopus 로고    scopus 로고
    • Maturation-induced cloaking of neutralization epitopes on HIV-1 particles
    • Joyner AS, Willis JR, Crowe JE, Jr, Aiken C. 2011. Maturation-induced cloaking of neutralization epitopes on HIV-1 particles. PLoS Pathog 7:e1002234. http://dx.doi.org/10.1371/journal.ppat.1002234.
    • (2011) PLoS Pathog , vol.7
    • Joyner, A.S.1    Willis, J.R.2    Crowe, J.E.3    Aiken, C.4


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