메뉴 건너뛰기




Volumn 85, Issue 14, 2011, Pages 7029-7036

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; EPITOPE; GLYCOPROTEIN GP 120; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 17B; MONOCLONAL ANTIBODY 2G12; MONOCLONAL ANTIBODY A32; UNCLASSIFIED DRUG;

EID: 79960342938     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00171-11     Document Type: Article
Times cited : (197)

References (37)
  • 1
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndromeassociated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi, A., et al. 1986. Production of acquired immunodeficiency syndromeassociated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:284-291.
    • (1986) J. Virol. , vol.59 , pp. 284-291
    • Adachi, A.1
  • 2
    • 39049094267 scopus 로고    scopus 로고
    • Human IgG/Fc gamma R interactions are modulated by streptococcal IgG glycan hydrolysis
    • Allhorn, M., A. I. Olin, F. Nimmerjahn, and M. Collin. 2008. Human IgG/Fc gamma R interactions are modulated by streptococcal IgG glycan hydrolysis. PLoS One 3:e1413.
    • (2008) PLoS One , vol.3
    • Allhorn, M.1    Olin, A.I.2    Nimmerjahn, F.3    Collin, M.4
  • 3
    • 0030240623 scopus 로고    scopus 로고
    • HIV- 1 gp120-specific antibody-dependent cellmediated cytotoxicity correlates with rate of disease progression
    • Baum, L. L., et al. 1996. HIV-1 gp120-specific antibody-dependent cellmediated cytotoxicity correlates with rate of disease progression. J. Immunol. 157:2168-2173.
    • (1996) J. Immunol. , vol.157 , pp. 2168-2173
    • Baum, L.L.1
  • 5
    • 60549104848 scopus 로고    scopus 로고
    • Rapid degranulation of NK cells following activation by HIV-specific antibodies
    • Chung, A. W., E. Rollman, R. J. Center, S. J. Kent, and I. Stratov. 2009. Rapid degranulation of NK cells following activation by HIV-specific antibodies. J. Immunol. 182:1202-1210.
    • (2009) J. Immunol. , vol.182 , pp. 1202-1210
    • Chung, A.W.1    Rollman, E.2    Center, R.J.3    Kent, S.J.4    Stratov, I.5
  • 6
    • 0026012053 scopus 로고
    • Preparation and characterization of an intravenous solution of IgG from human immunodeficiency virus-seropositive donors
    • Cummins, L. M., et al. 1991. Preparation and characterization of an intravenous solution of IgG from human immunodeficiency virus-seropositive donors. Blood 77:1111-1117.
    • (1991) Blood , vol.77 , pp. 1111-1117
    • Cummins, L.M.1
  • 7
    • 20844448731 scopus 로고    scopus 로고
    • Antigenic conservation and immunogenicity of the HIV coreceptor binding site
    • Decker, J. M., et al. 2005. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. J. Exp. Med. 201:1407-1419.
    • (2005) J. Exp. Med. , vol.201 , pp. 1407-1419
    • Decker, J.M.1
  • 8
    • 78049255341 scopus 로고    scopus 로고
    • Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC
    • Edmonds, T. G., et al. 2010. Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC. Virology 408:1-13.
    • (2010) Virology , vol.408 , pp. 1-13
    • Edmonds, T.G.1
  • 9
    • 0031037693 scopus 로고    scopus 로고
    • Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers
    • Ferrari, G., et al. 1997. Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers. Proc. Natl. Acad. Sci. U. S. A. 94:1396-1401.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 1396-1401
    • Ferrari, G.1
  • 10
    • 0034759248 scopus 로고    scopus 로고
    • Antigenic properties of the human immunodeficiency virus envelope during cell-cell fusion
    • Finnegan, C. M., W. Berg, G. K. Lewis, and A. L. DeVico. 2001. Antigenic properties of the human immunodeficiency virus envelope during cell-cell fusion. J. Virol. 75:11096-11105.
    • (2001) J. Virol. , vol.75 , pp. 11096-11105
    • Finnegan, C.M.1    Berg, W.2    Lewis, G.K.3    DeVico, A.L.4
  • 11
    • 65449179917 scopus 로고    scopus 로고
    • Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines
    • Florese, R. H., et al. 2009. Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines. J. Immunol. 182: 3718-3727.
    • (2009) J. Immunol. , vol.182 , pp. 3718-3727
    • Florese, R.H.1
  • 12
    • 0033375327 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity independently predicts survival in severely immunocompromised human immunodeficiency virus-infected patients
    • Forthal, D. N., et al. 1999. Antibody-dependent cellular cytotoxicity independently predicts survival in severely immunocompromised human immunodeficiency virus-infected patients. J. Infect. Dis. 180:1338-1341.
    • (1999) J. Infect. Dis. , vol.180 , pp. 1338-1341
    • Forthal, D.N.1
  • 13
    • 13544277161 scopus 로고    scopus 로고
    • Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251
    • Gómez-Román, V. R., et al. 2005. Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251. J. Immunol. 174:2185-2189.
    • (2005) J. Immunol. , vol.174 , pp. 2185-2189
    • Gómez-Román, V.R.1
  • 14
    • 34249940652 scopus 로고    scopus 로고
    • Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection
    • Gray, E. S., et al. 2007. Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection. J. Virol. 81:6187-6196.
    • (2007) J. Virol. , vol.81 , pp. 6187-6196
    • Gray, E.S.1
  • 16
    • 34548496893 scopus 로고    scopus 로고
    • Fc receptor but not complement binding is important in antibody protection against HIV
    • Hessell, A. J., et al. 2007. Fc receptor but not complement binding is important in antibody protection against HIV. Nature 449:101-104.
    • (2007) Nature , vol.449 , pp. 101-104
    • Hessell, A.J.1
  • 17
    • 58149526770 scopus 로고    scopus 로고
    • Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques
    • Hidajat, R., et al. 2009. Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques. J. Virol. 83:791-801.
    • (2009) J. Virol. , vol.83 , pp. 791-801
    • Hidajat, R.1
  • 18
    • 44649102135 scopus 로고    scopus 로고
    • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
    • Keele, B. F., et al. 2008. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl. Acad. Sci. U. S. A. 105:7552-7557.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 7552-7557
    • Keele, B.F.1
  • 19
    • 0036173941 scopus 로고    scopus 로고
    • Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates
    • Liu, L., et al. 2002. Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates. Nat. Med. 8:185-189.
    • (2002) Nat. Med. , vol.8 , pp. 185-189
    • Liu, L.1
  • 20
    • 0025181668 scopus 로고
    • Antibodies mediating cellular cytotoxicity and neutralization correlate with a better clinical stage in children born to human immunodeficiency virus-infected mothers
    • Ljunggren, K., et al. 1990. Antibodies mediating cellular cytotoxicity and neutralization correlate with a better clinical stage in children born to human immunodeficiency virus-infected mothers. J. Infect. Dis. 161:198-202.
    • (1990) J. Infect. Dis. , vol.161 , pp. 198-202
    • Ljunggren, K.1
  • 21
    • 0023376513 scopus 로고
    • Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to determinants on normal lymphocytes and expressed by infected cells serves as targets for immune attack
    • Lyerly, H. K., T. J. Matthews, A. J. Langlois, D. P. Bolognesi, and K. J. Weinhold. 1987. Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to determinants on normal lymphocytes and expressed by infected cells serves as targets for immune attack. Proc. Natl. Acad. Sci. U. S. A. 84:4601-4605.
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 4601-4605
    • Lyerly, H.K.1    Matthews, T.J.2    Langlois, A.J.3    Bolognesi, D.P.4    Weinhold, K.J.5
  • 22
    • 0030043169 scopus 로고    scopus 로고
    • Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein
    • Moore, J. P., and J. Sodroski. 1996. Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein. J. Virol. 70:1863-1872.
    • (1996) J. Virol. , vol.70 , pp. 1863-1872
    • Moore, J.P.1    Sodroski, J.2
  • 23
    • 45549101222 scopus 로고    scopus 로고
    • Analyzing antibody-Fc-receptor interactions
    • Nimmerjahn, F., and J. V. Ravetch. 2008. Analyzing antibody-Fc-receptor interactions. Methods Mol. Biol. 415:151-162.
    • (2008) Methods Mol. Biol. , vol.415 , pp. 151-162
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 24
    • 0033780046 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
    • O'Doherty, U., W. J. Swiggard, and M. H. Malim. 2000. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding. J. Virol. 74:10074-10080.
    • (2000) J. Virol. , vol.74 , pp. 10074-10080
    • O'Doherty, U.1    Swiggard, W.J.2    Malim, M.H.3
  • 25
    • 48549105161 scopus 로고    scopus 로고
    • Molecular engineering and design of therapeutic antibodies
    • Presta, L. G. 2008. Molecular engineering and design of therapeutic antibodies. Curr. Opin. Immunol. 20:460-470.
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 460-470
    • Presta, L.G.1
  • 26
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm, S., et al. 2009. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 361:2209-2220.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2209-2220
    • Rerks-Ngarm, S.1
  • 27
    • 33646723851 scopus 로고    scopus 로고
    • High frequencies of antibody responses to CD4 induced epitopes in HIV infected patients started on HAART during acute infection
    • Robinson, J. E., D. H. Elliott, E. A. Martin, K. Micken, and E. S. Rosenberg. 2005. High frequencies of antibody responses to CD4 induced epitopes in HIV infected patients started on HAART during acute infection. Hum. Antibodies 14:115-121.
    • (2005) Hum. Antibodies. , vol.14 , pp. 115-121
    • Robinson, J.E.1    Elliott, D.H.2    Martin, E.A.3    Micken, K.4    Rosenberg, E.S.5
  • 28
    • 66049139947 scopus 로고    scopus 로고
    • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
    • Salazar-Gonzalez, J. F., et al. 2009. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J. Exp. Med. 206:1273-1289.
    • (2009) J. Exp. Med. , vol.206 , pp. 1273-1289
    • Salazar-Gonzalez, J.F.1
  • 29
    • 43949145619 scopus 로고    scopus 로고
    • Robust NK cell-mediated human immunodeficiency virus (HIV)-specific antibody-dependent responses in HIV-infected subjects
    • Stratov, I., A. Chung, and S. J. Kent. 2008. Robust NK cell-mediated human immunodeficiency virus (HIV)-specific antibody-dependent responses in HIV-infected subjects. J. Virol. 82:5450-5459.
    • (2008) J. Virol. , vol.82 , pp. 5450-5459
    • Stratov, I.1    Chung, A.2    Kent, S.J.3
  • 30
    • 0027256814 scopus 로고
    • Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding
    • Thali, M., et al. 1993. Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding. J. Virol. 67:3978-3988.
    • (1993) J. Virol. , vol.67 , pp. 3978-3988
    • Thali, M.1
  • 31
    • 0032828730 scopus 로고    scopus 로고
    • A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor
    • Trkola, A., J. Matthews, C. Gordon, T. Ketas, and J. P. Moore. 1999. A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor. J. Virol. 73:8966-8974.
    • (1999) J. Virol. , vol.73 , pp. 8966-8974
    • Trkola, A.1    Matthews, J.2    Gordon, C.3    Ketas, T.4    Moore, J.P.5
  • 32
    • 9044241681 scopus 로고    scopus 로고
    • Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
    • Trkola, A., et al. 1996. Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1. J. Virol. 70:1100-1108.
    • (1996) J. Virol. , vol.70 , pp. 1100-1108
    • Trkola, A.1
  • 33
    • 0025223369 scopus 로고
    • Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies
    • Tyler, D. S., et al. 1990. Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies. J. Immunol. 145:3276-3282.
    • (1990) J. Immunol. , vol.145 , pp. 3276-3282
    • Tyler, D.S.1
  • 34
    • 0029119783 scopus 로고
    • Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding
    • Wyatt, R., et al. 1995. Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding. J. Virol. 69:5723-5733.
    • (1995) J. Virol. , vol.69 , pp. 5723-5733
    • Wyatt, R.1
  • 35
    • 77953756732 scopus 로고    scopus 로고
    • Multiple vaccine-elicited nonneutralizing anti-envelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following SHIV89 6P challenge in rhesus macaques
    • Xiao, P., et al. 2010. Multiple vaccine-elicited nonneutralizing anti-envelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following SHIV89.6P challenge in rhesus macaques. J. Virol. 84:7161-7173.
    • (2010) J. Virol. , vol.84 , pp. 7161-7173
    • Xiao, P.1
  • 36
    • 77954943648 scopus 로고    scopus 로고
    • Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
    • Zhou, T., et al. 2010. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science 329:811-817.
    • (2010) Science , vol.329 , pp. 811-817
    • Zhou, T.1
  • 37
    • 0029039317 scopus 로고
    • Serotyping of primary human immunodeficiency virus type 1 isolates from diverse geographic locations by flow cytometry
    • Zolla-Pazner, S., et al. 1995. Serotyping of primary human immunodeficiency virus type 1 isolates from diverse geographic locations by flow cytometry. J. Virol. 69:3807-3815.
    • (1995) J. Virol. , vol.69 , pp. 3807-3815
    • Zolla-Pazner, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.