Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors

Molecular and Cellular Neuroscience

Volumn 68, Issue , 2015, Pages 131-142

  Nouri, Navid ^a   Patel, Meera J ^a,c   Joksimovic, Milan ^a,d   Poulin, Jean Francois ^a   Anderegg, Angela ^a   Taketo, M Mark ^b   Ma, Yong Chao ^a   Awatramani, Rajeshwar ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF CHICAGO   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Floor plate; Lmx1b; Midbrain dopaminergic neurons; Wnt beta catenin

Indexed keywords

BETA CATENIN; DOPAMINE; HEPATOCYTE NUCLEAR FACTOR 3BETA; LMX1A PROTEIN; LMX1B PROTEIN; NEUROGENIN 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR POU4F1; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; WNT PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CTNNB1 PROTEIN, MOUSE; GT(ROSA)26SOR NON-CODING RNA, MOUSE; NERVE PROTEIN; NEUROG1 PROTEIN, MOUSE; SHH PROTEIN, MOUSE; UNTRANSLATED RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA CATENIN SIGNALING; CELL COUNT; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOWN REGULATION; EMBRYO; FEMALE; GENE EXPRESSION; MALE; MESENCEPHALON; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA PARS COMPACTA; WNT SIGNALING PATHWAY; AGE; ANIMAL; CYTOLOGY; EMBRYOLOGY; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENETICS; MAMMALIAN EMBRYO; METABOLISM; MORPHOGENESIS; PHYSIOLOGY; TRANSGENIC MOUSE;

AGE FACTORS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA CATENIN; BODY PATTERNING; DOPAMINE; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; MALE; MESENCEPHALON; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEUROGENESIS; RNA, UNTRANSLATED; TYROSINE 3-MONOOXYGENASE; WNT SIGNALING PATHWAY;

EID: 84937678526     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2015.07.002     Document Type: Article

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