An Lmx1b-miR135a2 Regulatory Circuit Modulates Wnt1/Wnt Signaling and Determines the Size of the Midbrain Dopaminergic Progenitor Pool

PLoS Genetics

Volumn 9, Issue 12, 2013, Pages

  Anderegg, Angela ^a   Lin, Hsin Pin ^a   Chen, Jun An ^b   Caronia Brown, Giuliana ^a   Cherepanova, Natalya ^a   Yun, Beth ^a   Joksimovic, Milan ^a   Rock, Jason ^c   Harfe, Brian D ^c   Johnson, Randy ^d   Awatramani, Rajeshwar ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^c UNIVERSITY OF FLORIDA   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DICER1 PROTEIN; LMX1A PROTEIN; LMX1B PROTEIN; MICRORNA; MICRORNA 135A2; REGULATOR PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 2; UNCLASSIFIED DRUG; WNT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; BRAIN NERVE CELL; BRAIN REGION; BRAIN SIZE; CCND1 GENE; CELL EXPANSION; CELL LOSS; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA SEQUENCE; EMBRYO; EMBRYONIC STEM CELL; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GSK3B GENE; IN VIVO STUDY; INTRON; MALE; MESENCEPHALON; MOLECULAR DYNAMICS; MOUSE; NEGATIVE FEEDBACK; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DETERMINATION; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SURVIVAL RATE; TCF7L2 GENE;

ANIMALS; CELL DIFFERENTIATION; DEAD-BOX RNA HELICASES; DOPAMINE; DOPAMINERGIC NEURONS; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; LIM-HOMEODOMAIN PROTEINS; MESENCEPHALON; MICE; MICRORNAS; NEUROGENESIS; PARKINSON DISEASE; RIBONUCLEASE III; TRANSCRIPTION FACTORS; WNT SIGNALING PATHWAY; WNT1 PROTEIN;

EID: 84892747763     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003973     Document Type: Article

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