Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors

Development (Cambridge)

Volumn 139, Issue 14, 2012, Pages 2625-2634

  Metzakopian, Emmanouil ^a   Lin, Wei ^a   Salmon Divon, Mali ^b,f   Dvinge, Heidi ^b   Andersson, Elisabet ^c   Ericson, Johan ^c   Perlmann, Thomas ^c   Whitsett, Jeffrey A ^d   Bertone, Paul ^b,e   Ang, Siew Lan ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c KAROLINSKA INSTITUTE   (Sweden)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^f SHEBA MEDICAL CENTER   (Israel)

Author keywords

Chromatin immunoprecipitation; Dopaminergic neuron specification; Floor plate; Forkhead; Foxa2; Mouse

Indexed keywords

FERD3L PROTEIN; HELT PROTEIN; HEPATOCYTE NUCLEAR FACTOR 3BETA; LMX1A; LMX1A PROTEIN; LMX1B PROTEIN; OTX1 PROTEIN; TAL2 PROTEIN; TLE4 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR SOX1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CHICK; CHROMATIN IMMUNOPRECIPITATION; DNA SEQUENCE; DOPAMINERGIC NERVE CELL; EMBRYO; GENE REGULATORY NETWORK; GENE REPRESSION; GENOME; HIGH THROUGHPUT SCREENING; MESENCEPHALON; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL; UPREGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DOPAMINERGIC NEURONS; ELECTROPORATION; GENOTYPE; HEPATOCYTE NUCLEAR FACTOR 3-BETA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIM-HOMEODOMAIN PROTEINS; MESENCEPHALON; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MSX1 TRANSCRIPTION FACTOR; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PROTEIN BINDING; SOXB1 TRANSCRIPTION FACTORS; STEM CELLS; TRANSCRIPTION FACTORS;

EID: 84863107502     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.081034     Document Type: Article

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