메뉴 건너뛰기




Volumn 13, Issue , 2007, Pages 265-301

Ganoderma lucidum and its pharmaceutically active compounds

Author keywords

d glucans; anti cancer effects; cultivation; Ganoderma lucidum; immunomodulation.; pharmacological effects; polysaccharides; sawdust; solid state cultivation; submerged cultivation; triterpenoids; wood logs

Indexed keywords

ANTIDIABETIC AGENT; ANTINEOPLASTIC AGENT; BETA GLUCAN; CHOLESTEROL; COMPLEMENT; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE; FREE RADICAL; GAMMA INTERFERON; GANODERMA LUCIDUM EXTRACT; HISTAMINE; MUTAGENIC AGENT; POLYSACCHARIDE; TRITERPENOID; TUMOR NECROSIS FACTOR ALPHA;

EID: 34548598182     PISSN: 13872656     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1387-2656(07)13010-6     Document Type: Review
Times cited : (470)

References (153)
  • 1
    • 34548558181 scopus 로고    scopus 로고
    • Leung SWS. Lingzhi (Ganoderma) research - the past, present and future perspectives. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, Beijing, Medical University Press, 2002, pp. 1-9.
  • 2
    • 34548554006 scopus 로고    scopus 로고
    • Kim HW and Kim BK. Recent advances on the biologically active triterpenoids of Ganoderma lucidum. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, Beijing, Medical University Press, 2002, pp. 10-19.
  • 3
    • 0026682524 scopus 로고
    • Medicinal benefits of the mushrooms Ganoderma
    • Jong S.C., and Birmingham J.M. Medicinal benefits of the mushrooms Ganoderma. Adv Appl Microbiol 37 (1992) 101-134
    • (1992) Adv Appl Microbiol , vol.37 , pp. 101-134
    • Jong, S.C.1    Birmingham, J.M.2
  • 4
    • 0023909608 scopus 로고
    • Anti-allergic constituents in the culture medium of Ganoderma lucidum. 1. Inhibitory effect of oleic acid on histamine release
    • Tasaka K., Akagi M., Miyoshi K., Mio M., and Makino T. Anti-allergic constituents in the culture medium of Ganoderma lucidum. 1. Inhibitory effect of oleic acid on histamine release. Agents Action 23 (1988) 153-156
    • (1988) Agents Action , vol.23 , pp. 153-156
    • Tasaka, K.1    Akagi, M.2    Miyoshi, K.3    Mio, M.4    Makino, T.5
  • 7
    • 0024558193 scopus 로고
    • Antitumor activity of Sarcodon aspratus (Berk.) S. Ito and Ganoderma lucidum (Fr.) Karst
    • Maruyama H., Yamazaki K., Murofushi S., Konda C., and Ikekawa T. Antitumor activity of Sarcodon aspratus (Berk.) S. Ito and Ganoderma lucidum (Fr.) Karst. J Pharmacobio-Dyn 12 (1989) 118-123
    • (1989) J Pharmacobio-Dyn , vol.12 , pp. 118-123
    • Maruyama, H.1    Yamazaki, K.2    Murofushi, S.3    Konda, C.4    Ikekawa, T.5
  • 8
    • 0025033642 scopus 로고
    • Cardiovascular effects of mycelium extract of Ganoderma lucidum - inhibition of sympathetic outflow as a mechanism of its hypotensive action
    • Lee S.Y., and Rhee H M. Cardiovascular effects of mycelium extract of Ganoderma lucidum - inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull 38 (1990) 1359-1364
    • (1990) Chem Pharm Bull , vol.38 , pp. 1359-1364
    • Lee, S.Y.1    Rhee H, M.2
  • 9
    • 0018287510 scopus 로고
    • Some pharmacological actions of the spores of Ganoderma lucidum and the mycelium of Ganoderma capense (Lloyd) Teng cultivated by submerged fermentation
    • Liu G.T., Bao X., Niu S., Li Z., and Sung Z. Some pharmacological actions of the spores of Ganoderma lucidum and the mycelium of Ganoderma capense (Lloyd) Teng cultivated by submerged fermentation. Chin Med J 92 (1979) 469-500
    • (1979) Chin Med J , vol.92 , pp. 469-500
    • Liu, G.T.1    Bao, X.2    Niu, S.3    Li, Z.4    Sung, Z.5
  • 10
    • 34548596103 scopus 로고    scopus 로고
    • Hirose K, Muto S, Niimura K, Ohara M, Oguchi Y, Matsunaga K, Kadochi J, Sugita N, Furushu T, Yoshikumi C and Takahashi M. Antiviral agent. Japanese Patent JP 63316734, 1988.
  • 11
    • 34548589732 scopus 로고    scopus 로고
    • Mizumoto K, Yamashita A, Kii M and Sumio H. Antiretrovirus agent. Japanese Patent JP 2032026, 1990.
  • 12
    • 0038634342 scopus 로고    scopus 로고
    • Kim HW, Shim MJ, Choi EC and Kim BK. Inhibition of cytopathic effect of human immunodeficiency virus-1 by water-soluble extract of Ganoderma lucidum. Arch Pharm Res 1997;20:425-431.
  • 13
    • 34548562999 scopus 로고    scopus 로고
    • Hattori M, El-Mekkawy S and Meselhy R. Inhibitory effects of components from Ganoderma lucidum on the growth of human immunodeficiency virus (HIV) and the protease activity. In: Proceedings of the 1st International Symposium on Ganoderma Lucidum in Japan, Mizuno T, Ide N and Hasegawa Y (eds), November 17-18, 1997, pp. 128-135.
  • 15
    • 0031795507 scopus 로고    scopus 로고
    • Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease
    • Min B.S., Nakamura N., Miyashiro H., Bae K W., and Hattori M. Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chem Pharm Bull 46 (1998) 1607-1612
    • (1998) Chem Pharm Bull , vol.46 , pp. 1607-1612
    • Min, B.S.1    Nakamura, N.2    Miyashiro, H.3    Bae K, W.4    Hattori, M.5
  • 16
    • 34548579677 scopus 로고    scopus 로고
    • Triratana S, Thaithatgoon S and Gawgla M. Cultivation of Ganoderma lucidum in sawdust bags. In: Science and Cultivation of Edible Fungi, Maher MJ (ed), Proceedings of the 13th International Congress on the Science Cultivation of Edible Fungi, Dublin, September 1-6, 1991, Rotterdam, A. A. Balkema, pp. 567-572.
  • 17
    • 7144247226 scopus 로고
    • Polysaccharides in mycelial culture of Ganoderma applanatum (Pers.) Pat
    • Kohlmünzer S., Wegiel J., and Sitarz J. Polysaccharides in mycelial culture of Ganoderma applanatum (Pers.) Pat. Herba Hung 28 (1989) 87-94
    • (1989) Herba Hung , vol.28 , pp. 87-94
    • Kohlmünzer, S.1    Wegiel, J.2    Sitarz, J.3
  • 18
    • 34548576385 scopus 로고    scopus 로고
    • Lin SQ, Wang SZ, Lin SG and Lin ZB. Studies on Ganoderma submerged fermentation and its product extraction technique. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 93-97.
  • 19
    • 0034412845 scopus 로고    scopus 로고
    • The relevance of solid-state substrate moisturing on Ganoderma lucidum biomass cultivation
    • Habijanic J., and Berovic M. The relevance of solid-state substrate moisturing on Ganoderma lucidum biomass cultivation. Food Technol Biotechnol 38 (2000) 225-228
    • (2000) Food Technol Biotechnol , vol.38 , pp. 225-228
    • Habijanic, J.1    Berovic, M.2
  • 20
    • 0038737167 scopus 로고    scopus 로고
    • Submerged cultivation of Ganoderma lucidum biomass and immunostimulatory effects of fungal polysaccharides
    • Berovic M., Habijanic J., Zore I., Wraber B., Hodzar D., Boh B., and Pohleven F. Submerged cultivation of Ganoderma lucidum biomass and immunostimulatory effects of fungal polysaccharides. J Biotechnol 103 (2003) 77-86
    • (2003) J Biotechnol , vol.103 , pp. 77-86
    • Berovic, M.1    Habijanic, J.2    Zore, I.3    Wraber, B.4    Hodzar, D.5    Boh, B.6    Pohleven, F.7
  • 21
    • 84950000772 scopus 로고
    • Reishi, Ganoderma lucidum and Ganoderma tsugae: bioactive substance and medicinal effects
    • Mizuno T., Wang G., Zhang J., Kawagishi H., Nishitoba T., and Li J. Reishi, Ganoderma lucidum and Ganoderma tsugae: bioactive substance and medicinal effects. Food Rev Int 11 (1995) 151-166
    • (1995) Food Rev Int , vol.11 , pp. 151-166
    • Mizuno, T.1    Wang, G.2    Zhang, J.3    Kawagishi, H.4    Nishitoba, T.5    Li, J.6
  • 22
    • 0038572296 scopus 로고
    • Chemical structures and changes of extracts during growth of reishi (Ganoderma lucidum)
    • Miyahara R., Yoshimoto T., and Asawa K. Chemical structures and changes of extracts during growth of reishi (Ganoderma lucidum). Mokuzai Gakkaishi 33 (1987) 416-422
    • (1987) Mokuzai Gakkaishi , vol.33 , pp. 416-422
    • Miyahara, R.1    Yoshimoto, T.2    Asawa, K.3
  • 23
    • 34548579674 scopus 로고    scopus 로고
    • Chan K. Linking chemical and biological characteristics in assuring the quality of Chinese medicinal materials and OTC products. In: L Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 24-34.
  • 24
    • 34548545871 scopus 로고    scopus 로고
    • Lee JH. Cultivation of reishi (Ganoerma lucidum) [online]. MushWorld - Cultivation, 2000-12-24, available at http://www.mushworld.com/sub_en.html
  • 25
    • 34548558176 scopus 로고    scopus 로고
    • Chen AW. A fresh look at an ancient mushroom Ganoderma lucidum (Reishi) [online]. MushWorld - Cultivation, 2003-03-18, available at http://www.mushworld.com/sub_en.html
  • 26
    • 34548545872 scopus 로고    scopus 로고
    • Chen AW. Natural-log cultivation of the medicinal mushroom Ganoderma lucidum (Reishi) [online]. MushWorld - Cultivation, 2004-01-09, available at http://www.mushworld.com/sub_en.html
  • 27
    • 34548582654 scopus 로고    scopus 로고
    • Sukarno N. Development of Ganoderma lucidum on soft and hard wood logs and determination of organic germanium and ganoderic acid content of the fruiting body produced [online]. MushWorld - Cultivation, 2004-10-06, available at http://www.mushworld.com/sub_en.html
  • 28
    • 34548565168 scopus 로고    scopus 로고
    • Chen AW. Cultivation of the medicinal mushroom Ganoderma lucidum (Curt.: Fr.) P. Karst (Reishi) in North America (3) [online]. MushWorld - Cultivation, 2002-02-01, available at http://www.mushworld.com/sub_en.html
  • 29
    • 0005825420 scopus 로고    scopus 로고
    • Specialty mushrooms
    • Janick J. (Ed), ASHS Press, Arlington, VA
    • Royse D.J. Specialty mushrooms. In: Janick J. (Ed). Progress in New Crops (1996), ASHS Press, Arlington, VA 464-475
    • (1996) Progress in New Crops , pp. 464-475
    • Royse, D.J.1
  • 30
    • 34548589731 scopus 로고    scopus 로고
    • Chen AW. Growing Ganoderma mushrooms. In: Mushroom Grower's Handbook I, Part III: Mushrooms Worldwide, Chapter 11: Mushrooms for the tropics. ISSN 1739-1377, [online]. MushWorld, 2004, pp. 224-234, available at http://www.mushworld.com/service/handbook/english/eng-book1/chapter11-01_p.224.pdf
  • 31
    • 34548597709 scopus 로고    scopus 로고
    • Yukinori S, Tetsuji S and Yasushi S. Cultivation of Ganoderma lucidum Karst. Patent JP11146728, JMC KK, 1999-06-02.
  • 32
    • 34548578342 scopus 로고    scopus 로고
    • Furci George-Nascimento GM. Ganoderma lucidum (Curt.:Fr.) P. Karst grown indoors on native Chilean hardwoods [online]. MushWorld - Cultivation, 2005-07-30, available at http://www.mushworld.com/sub_en.html
  • 34
    • 0242409163 scopus 로고    scopus 로고
    • Use of stillage grain from a rice-spirit distillery in the solid state fermentation of Ganoderma lucidum
    • Yang F.C., Hsieh C., and Chen H.M. Use of stillage grain from a rice-spirit distillery in the solid state fermentation of Ganoderma lucidum. Process Biochem 39 (2003) 21-26
    • (2003) Process Biochem , vol.39 , pp. 21-26
    • Yang, F.C.1    Hsieh, C.2    Chen, H.M.3
  • 35
    • 0142227016 scopus 로고    scopus 로고
    • Reusing soy residue for the solid-state fermentation of Ganoderma lucidum
    • Hsieh C., and Yang F.C. Reusing soy residue for the solid-state fermentation of Ganoderma lucidum. Bioresour Technol 91 (2004) 105-109
    • (2004) Bioresour Technol , vol.91 , pp. 105-109
    • Hsieh, C.1    Yang, F.C.2
  • 36
    • 34548579675 scopus 로고    scopus 로고
    • Kim HK. Comparison of characteristics of Ganoderma lucidum according to geographical origins: consideration of growth characteristics (1) [online]. MushWorld - World Mushroom, 2001-09-01, available at http://www.mushworld.com/sub_en.html
  • 37
    • 34548579676 scopus 로고    scopus 로고
    • Takashi M. Apparatus for cultivating Ganoderma lucidum Karst and other mushrooms and their cultivation. Patent JP11155366, 1999.
  • 38
    • 34548560165 scopus 로고    scopus 로고
    • Kiyoshi K, Hamajirou S and Yoshiaki A. Cultivation method for Ganoderma lucidum (fr.) Karst. Patent JP10084772, 1998.
  • 39
    • 34548555159 scopus 로고    scopus 로고
    • Shigeru Y. Cultivation of Reishi. Patent JP3083521, 1991.
  • 40
    • 34548597710 scopus 로고    scopus 로고
    • Habjanic J and Berovic M. Process of cultivation of fungus Ganoderma lucidum on a solid cultivation substrate. Patent SI 20923, 2002.
  • 41
    • 34548545873 scopus 로고    scopus 로고
    • Li PJ and Shen CG. Method for propagating fungi using solid state fermentation. Patent WO0220727, 2002.
  • 42
    • 28844502743 scopus 로고    scopus 로고
    • Optimization of the medium composition for the submerged culture of Ganoderma lucidum by Taguchi array design and steepest ascent method
    • Chang M.Y., Tsai G.J., and Houng J.Y. Optimization of the medium composition for the submerged culture of Ganoderma lucidum by Taguchi array design and steepest ascent method. Enzyme Microb Technol 38 (2006) 407-414
    • (2006) Enzyme Microb Technol , vol.38 , pp. 407-414
    • Chang, M.Y.1    Tsai, G.J.2    Houng, J.Y.3
  • 43
    • 27844594899 scopus 로고    scopus 로고
    • Production of polysaccharides from Ganoderma lucidum (CCRC 36041) under limitations of nutrients
    • Hsieh C., Tseng M.H., and Liu C.J. Production of polysaccharides from Ganoderma lucidum (CCRC 36041) under limitations of nutrients. Enzyme Microb Technol 38 (2006) 109-117
    • (2006) Enzyme Microb Technol , vol.38 , pp. 109-117
    • Hsieh, C.1    Tseng, M.H.2    Liu, C.J.3
  • 44
    • 34548584519 scopus 로고    scopus 로고
    • Zore I, Berovic M, Boh B, Hodzar D and Pohleven F. Procedure for preparation of inoculum for growing of fungus Ganoderma lucidum by submersion fermentation. Patent SI 9700014, 1998.
  • 45
    • 0032104040 scopus 로고    scopus 로고
    • The influence of environmental conditions on polysaccharide formation by Ganoderma lucidum in submerged cultures
    • Yang F.C., and Liau C.B. The influence of environmental conditions on polysaccharide formation by Ganoderma lucidum in submerged cultures. Process Biochem 33 (1998) 547-553
    • (1998) Process Biochem , vol.33 , pp. 547-553
    • Yang, F.C.1    Liau, C.B.2
  • 46
    • 0033394195 scopus 로고    scopus 로고
    • Bistage control of pH for improving exopolysaccharide production from mycelia of Ganoderma lucidum in an air-lift fermentor
    • Lee K.M., Lee S.Y., and Lee H.Y. Bistage control of pH for improving exopolysaccharide production from mycelia of Ganoderma lucidum in an air-lift fermentor. J Biosci Bioeng 88 (1999) 646-650
    • (1999) J Biosci Bioeng , vol.88 , pp. 646-650
    • Lee, K.M.1    Lee, S.Y.2    Lee, H.Y.3
  • 47
    • 0036148325 scopus 로고    scopus 로고
    • Effect of initial pH on production of ganoderic acid and polysaccharide by submerged fermentation of Ganoderma lucidum
    • Fang Q.H., and Zhong J.J. Effect of initial pH on production of ganoderic acid and polysaccharide by submerged fermentation of Ganoderma lucidum. Process Biochem 37 (2002) 769-774
    • (2002) Process Biochem , vol.37 , pp. 769-774
    • Fang, Q.H.1    Zhong, J.J.2
  • 48
    • 0036158901 scopus 로고    scopus 로고
    • Submerged fermentation of higher fungus Ganoderma lucidum for production of valuable bioactive metabolites - ganoderic acid and polysaccharide
    • Fang Q.H., and Zhong J.J. Submerged fermentation of higher fungus Ganoderma lucidum for production of valuable bioactive metabolites - ganoderic acid and polysaccharide. Biochem Eng J 10 (2002) 61-65
    • (2002) Biochem Eng J , vol.10 , pp. 61-65
    • Fang, Q.H.1    Zhong, J.J.2
  • 49
    • 0036660931 scopus 로고    scopus 로고
    • Significance of inoculation density control in production of polysaccharide and ganoderic acid by submerged culture of Ganoderma lucidum
    • Fang Q.H., Tang Y.j., and Zhong J.J. Significance of inoculation density control in production of polysaccharide and ganoderic acid by submerged culture of Ganoderma lucidum. Process Biochem 37 (2002) 1375-1379
    • (2002) Process Biochem , vol.37 , pp. 1375-1379
    • Fang, Q.H.1    Tang, Y.j.2    Zhong, J.J.3
  • 50
    • 0036644167 scopus 로고    scopus 로고
    • Fed-batch fermentation of Ganoderma lucidum for hyperproduction of polysaccharide and ganoderic acid
    • Tang Y.J., and Zhong J.J. Fed-batch fermentation of Ganoderma lucidum for hyperproduction of polysaccharide and ganoderic acid. Enzyme Microb Tech 31 (2002) 20-28
    • (2002) Enzyme Microb Tech , vol.31 , pp. 20-28
    • Tang, Y.J.1    Zhong, J.J.2
  • 51
    • 0037416690 scopus 로고    scopus 로고
    • Role of oxygen supply in submerged fermentation of Ganoderma lucidum for production of Ganoderma polysaccharide and ganoderic acid
    • Tang Y.J., and Zhong J.J. Role of oxygen supply in submerged fermentation of Ganoderma lucidum for production of Ganoderma polysaccharide and ganoderic acid. Enzyme Microb Technol 32 (2003) 478-484
    • (2003) Enzyme Microb Technol , vol.32 , pp. 478-484
    • Tang, Y.J.1    Zhong, J.J.2
  • 52
    • 7444225297 scopus 로고    scopus 로고
    • Production of polysaccharides of Ganoderma lucidum (CCRC36021) by reusing thin stillage
    • Hsieh C., Hsu T.H., and Yang F.C. Production of polysaccharides of Ganoderma lucidum (CCRC36021) by reusing thin stillage. Process Biochem 40 (2005) 909-916
    • (2005) Process Biochem , vol.40 , pp. 909-916
    • Hsieh, C.1    Hsu, T.H.2    Yang, F.C.3
  • 53
    • 0038407265 scopus 로고    scopus 로고
    • Production of Ganoderma lucidum mycelium using cheese whey as an alternative substrate: response surface analysis and biokinetics
    • Lee H., Song M., Yu Y., and Hwang S. Production of Ganoderma lucidum mycelium using cheese whey as an alternative substrate: response surface analysis and biokinetics. Biochem Eng J 15 (2003) 93-99
    • (2003) Biochem Eng J , vol.15 , pp. 93-99
    • Lee, H.1    Song, M.2    Yu, Y.3    Hwang, S.4
  • 54
    • 0043157862 scopus 로고    scopus 로고
    • Optimizing bioconversion of deproteinated cheese whey to mycelia of Ganoderma lucidum
    • Lee H., Song M., Yu Y., and Hwang S. Optimizing bioconversion of deproteinated cheese whey to mycelia of Ganoderma lucidum. Process Biochem 38 (2003) 1685-1693
    • (2003) Process Biochem , vol.38 , pp. 1685-1693
    • Lee, H.1    Song, M.2    Yu, Y.3    Hwang, S.4
  • 55
    • 85008122340 scopus 로고
    • Ganoderic acids T, S, and R, new triterpenoids from the cultured media of Ganoderma lucidum
    • Hirotani M., Ino C., Furuya T., and Shiro M. Ganoderic acids T, S, and R, new triterpenoids from the cultured media of Ganoderma lucidum. Chem Pharm Bull 34 (1986) 2282-2285
    • (1986) Chem Pharm Bull , vol.34 , pp. 2282-2285
    • Hirotani, M.1    Ino, C.2    Furuya, T.3    Shiro, M.4
  • 56
    • 0022966594 scopus 로고
    • Constituents of the fungus Ganoderma lucidum (Fr.) Karst. I. Structures of ganoderic acids C2, E, I, and K, lucidenic acid F and related compounds
    • Kikuchi T., Kanomi S., Murai Y., Kadota S., Tsubono K., and Ogita Z. Constituents of the fungus Ganoderma lucidum (Fr.) Karst. I. Structures of ganoderic acids C2, E, I, and K, lucidenic acid F and related compounds. Chem Pharm Bull 34 (1986) 3695-3712
    • (1986) Chem Pharm Bull , vol.34 , pp. 3695-3712
    • Kikuchi, T.1    Kanomi, S.2    Murai, Y.3    Kadota, S.4    Tsubono, K.5    Ogita, Z.6
  • 57
    • 0022451555 scopus 로고
    • Angiotensin converting enzyme inhibitory triterpenes from Ganoderma lucidum
    • Morigiwa A., Kitabatake K., Fujimoto Y., and Ikekawa N. Angiotensin converting enzyme inhibitory triterpenes from Ganoderma lucidum. Chem Pharm Bull 34 (1986) 3025-3028
    • (1986) Chem Pharm Bull , vol.34 , pp. 3025-3028
    • Morigiwa, A.1    Kitabatake, K.2    Fujimoto, Y.3    Ikekawa, N.4
  • 58
    • 0001028999 scopus 로고
    • Triterpenoids from the fungus Ganoderma lucidum
    • Nishitoba T., Sato H., and Sakamura S. Triterpenoids from the fungus Ganoderma lucidum. Phytochemistry 26 (1987) 1777-1784
    • (1987) Phytochemistry , vol.26 , pp. 1777-1784
    • Nishitoba, T.1    Sato, H.2    Sakamura, S.3
  • 59
    • 0001084709 scopus 로고
    • Bitter triterpenoids from the fungus Ganoderma applanatum
    • Nishitoba T., Goto S., Sato H., and Sakamura S. Bitter triterpenoids from the fungus Ganoderma applanatum. Phytochemistry 28 (1989) 193-197
    • (1989) Phytochemistry , vol.28 , pp. 193-197
    • Nishitoba, T.1    Goto, S.2    Sato, H.3    Sakamura, S.4
  • 60
    • 0343665077 scopus 로고
    • Seven new triterpenes from Ganoderma lucidum
    • Lin L.J., and Shiao M.S. Seven new triterpenes from Ganoderma lucidum. J Nat Prod 51 (1988) 918-924
    • (1988) J Nat Prod , vol.51 , pp. 918-924
    • Lin, L.J.1    Shiao, M.S.2
  • 61
    • 0007704892 scopus 로고
    • Triterpenes from Ganoderma lucidum
    • Lin L.J., Shiao M.S., and Yeh S.F. Triterpenes from Ganoderma lucidum. Phytochem 27 (1988) 2269-2271
    • (1988) Phytochem , vol.27 , pp. 2269-2271
    • Lin, L.J.1    Shiao, M.S.2    Yeh, S.F.3
  • 62
    • 0000577550 scopus 로고
    • Two new triterpenes of the fungus Ganoderma lucidum
    • Shiao M.S., Lin L.J., Yeh S.F., and Chou C.S. Two new triterpenes of the fungus Ganoderma lucidum. J Nat Prod 50 (1987) 886-890
    • (1987) J Nat Prod , vol.50 , pp. 886-890
    • Shiao, M.S.1    Lin, L.J.2    Yeh, S.F.3    Chou, C.S.4
  • 63
    • 0000487358 scopus 로고
    • Applanoxidic acids A, B, C and D, biologically active tetracyclic triterpenes from Ganoderma applanatum
    • Chairul, Tokuyama T., Hayashi Y., Nishizawa M., Tokuda H., Chairul S.M., and Hayashi Y. Applanoxidic acids A, B, C and D, biologically active tetracyclic triterpenes from Ganoderma applanatum. Phytochem 30 (1991) 4105-4109
    • (1991) Phytochem , vol.30 , pp. 4105-4109
    • Chairul1    Tokuyama, T.2    Hayashi, Y.3    Nishizawa, M.4    Tokuda, H.5    Chairul, S.M.6    Hayashi, Y.7
  • 64
    • 0027950552 scopus 로고
    • Lanostanoid triterpenes from Ganoderma applanatum
    • Chairul, Hayashi Y., and Chairul S.M. Lanostanoid triterpenes from Ganoderma applanatum. Phytochem 35 (1994) 1305-1308
    • (1994) Phytochem , vol.35 , pp. 1305-1308
    • Chairul1    Hayashi, Y.2    Chairul, S.M.3
  • 65
    • 0347269293 scopus 로고    scopus 로고
    • Isolation and quantification of triterpenoid acids from Ganoderma applanatum of Istrian origin
    • Boh B., Hodzar D., Dolnicar D., Berovic M., and Pohleven F. Isolation and quantification of triterpenoid acids from Ganoderma applanatum of Istrian origin. Food Technol Biotechnol 1 (2000) 11-18
    • (2000) Food Technol Biotechnol , vol.1 , pp. 11-18
    • Boh, B.1    Hodzar, D.2    Dolnicar, D.3    Berovic, M.4    Pohleven, F.5
  • 66
    • 0032963631 scopus 로고    scopus 로고
    • Beta-glucuronidase-inhibitory and hepatoprotective effect of Ganoderma lucidum
    • Kim D.H., Shim S.B., Kim N.J., and Jang I.S. Beta-glucuronidase-inhibitory and hepatoprotective effect of Ganoderma lucidum. Biol Pharm Bull 22 (1999) 162-164
    • (1999) Biol Pharm Bull , vol.22 , pp. 162-164
    • Kim, D.H.1    Shim, S.B.2    Kim, N.J.3    Jang, I.S.4
  • 67
    • 49049130542 scopus 로고
    • Les acides ganoderiques T a Z: triterpenes cytotoxiques de Ganoderma lucidum (Polyporaceae)
    • Toth J.O., Luu B., and Ourisson G. Les acides ganoderiques T a Z: triterpenes cytotoxiques de Ganoderma lucidum (Polyporaceae). Tetrahedron Lett 24 (1983) 1081-1084
    • (1983) Tetrahedron Lett , vol.24 , pp. 1081-1084
    • Toth, J.O.1    Luu, B.2    Ourisson, G.3
  • 68
    • 34548549823 scopus 로고    scopus 로고
    • Lin SB, Li CH, Chen YR, Kan LS and Lee SS. Triterpene extract from Ganoderma lucidum inhibits growth of hepatoma Huh7 cells: involvement of oxidative stress induction. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 176-182.
  • 69
    • 0036595422 scopus 로고    scopus 로고
    • New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells
    • Gao J.J., Min B.S., Ahn E.M., Nakamura N., Lee H.K., and Hattori M. New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells. Chem Pharm Bull (Tokyo) 50 (2002) 837-840
    • (2002) Chem Pharm Bull (Tokyo) , vol.50 , pp. 837-840
    • Gao, J.J.1    Min, B.S.2    Ahn, E.M.3    Nakamura, N.4    Lee, H.K.5    Hattori, M.6
  • 70
    • 0033930342 scopus 로고    scopus 로고
    • Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells
    • Min B.S., Gao J.J., Nakamura N., and Hattori M. Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells. Chem Pharm Bull (Tokyo) 48 (2000) 1026-1033
    • (2000) Chem Pharm Bull (Tokyo) , vol.48 , pp. 1026-1033
    • Min, B.S.1    Gao, J.J.2    Nakamura, N.3    Hattori, M.4
  • 71
    • 0037432498 scopus 로고    scopus 로고
    • Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest
    • Lin S.B., Li C.H., Lee S.S., and Kan L.S. Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest. Life Sci 72 (2003) 2381-2390
    • (2003) Life Sci , vol.72 , pp. 2381-2390
    • Lin, S.B.1    Li, C.H.2    Lee, S.S.3    Kan, L.S.4
  • 72
    • 0033798801 scopus 로고    scopus 로고
    • Effects of extracts from sporoderm-broken spores of Ganoderma lucidum on HeLa cells
    • Zhu H.S., Yang X.L., Wang L.B., Zhao D.X., and Chen L. Effects of extracts from sporoderm-broken spores of Ganoderma lucidum on HeLa cells. Cell Biol Toxicol 16 (2000) 201-206
    • (2000) Cell Biol Toxicol , vol.16 , pp. 201-206
    • Zhu, H.S.1    Yang, X.L.2    Wang, L.B.3    Zhao, D.X.4    Chen, L.5
  • 73
    • 33745086173 scopus 로고    scopus 로고
    • Correlation between intracellular triterpenes from mycelia of Ganoderma lucidum in different growth stages and inhibition effect on tumor cells
    • Yu S.P., Zhang J.S., Tang Q.J., Shi X.M., Liu Y.F., Yan Y., and Pan Y.L. Correlation between intracellular triterpenes from mycelia of Ganoderma lucidum in different growth stages and inhibition effect on tumor cells. Mycosystema 23 (2004) 548-554
    • (2004) Mycosystema , vol.23 , pp. 548-554
    • Yu, S.P.1    Zhang, J.S.2    Tang, Q.J.3    Shi, X.M.4    Liu, Y.F.5    Yan, Y.6    Pan, Y.L.7
  • 74
    • 33746522974 scopus 로고    scopus 로고
    • Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum
    • Liu J., Shimizu K., Konishi F., Noda K., Kumamoto S., Kurashiki K., and Kondo R. Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum. Food Chem 100 (2007) 1691-1696
    • (2007) Food Chem , vol.100 , pp. 1691-1696
    • Liu, J.1    Shimizu, K.2    Konishi, F.3    Noda, K.4    Kumamoto, S.5    Kurashiki, K.6    Kondo, R.7
  • 75
  • 76
    • 0036871314 scopus 로고    scopus 로고
    • Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance
    • Kimura Y., Taniguchi M., and Baba K. Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance. Anticancer Res 22 6A (2002) 3309-3318
    • (2002) Anticancer Res , vol.22 , Issue.6 A , pp. 3309-3318
    • Kimura, Y.1    Taniguchi, M.2    Baba, K.3
  • 77
    • 0023806613 scopus 로고
    • Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hipertensive rats
    • Kabir Y., Kimura S., and Tamura T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hipertensive rats. J Nat Sci Vitaminol 34 (1988) 433-438
    • (1988) J Nat Sci Vitaminol , vol.34 , pp. 433-438
    • Kabir, Y.1    Kimura, S.2    Tamura, T.3
  • 79
    • 0024433165 scopus 로고
    • The aggregation of human platelet induced by ganodermic acid S
    • Wang C.N., Chen J.C., Shiao M.S., and Wang C.T. The aggregation of human platelet induced by ganodermic acid S. Biochim Biophys Acta 986 (1989) 151-160
    • (1989) Biochim Biophys Acta , vol.986 , pp. 151-160
    • Wang, C.N.1    Chen, J.C.2    Shiao, M.S.3    Wang, C.T.4
  • 80
    • 0025816605 scopus 로고
    • The inhibition of human platelet function by ganodermic acids
    • Wang C.N., Chen J.C., Shiao M.S., and Wang C.T. The inhibition of human platelet function by ganodermic acids. Biochem J 277 (1991) 189-197
    • (1991) Biochem J , vol.277 , pp. 189-197
    • Wang, C.N.1    Chen, J.C.2    Shiao, M.S.3    Wang, C.T.4
  • 81
    • 0033602237 scopus 로고    scopus 로고
    • Predominant inhibition of ganodermic acid S on the thromboxane A2 -dependent pathway in human platelets response to collagen
    • Su C.Y., Shiao M.S., and Wang C.T. Predominant inhibition of ganodermic acid S on the thromboxane A2 -dependent pathway in human platelets response to collagen. Biochim Biophys Acta 1437 (1999) 223-234
    • (1999) Biochim Biophys Acta , vol.1437 , pp. 223-234
    • Su, C.Y.1    Shiao, M.S.2    Wang, C.T.3
  • 82
    • 0034661339 scopus 로고    scopus 로고
    • Potentiation of ganoderemic acid S on prostaglandin E(1)-induced cyclic AMP elevation in human platelets
    • Su C., Shiao M., and Wang C. Potentiation of ganoderemic acid S on prostaglandin E(1)-induced cyclic AMP elevation in human platelets. Thromb Res 99 (2000) 135-145
    • (2000) Thromb Res , vol.99 , pp. 135-145
    • Su, C.1    Shiao, M.2    Wang, C.3
  • 83
    • 0035668974 scopus 로고    scopus 로고
    • Anticomplement activity of triterpenoids from the spores of Ganoderma lucidum
    • Min B.S., Gao J.J., Hattori M., Lee H.K., and Kim Y.H. Anticomplement activity of triterpenoids from the spores of Ganoderma lucidum. Planta Med 67 (2001) 811-814
    • (2001) Planta Med , vol.67 , pp. 811-814
    • Min, B.S.1    Gao, J.J.2    Hattori, M.3    Lee, H.K.4    Kim, Y.H.5
  • 84
    • 34548560164 scopus 로고    scopus 로고
    • Fang JN, Bao XF and Yuen WH. Studies on the polysaccharides from spores of Ganoderma lucidum. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 98-103.
  • 85
    • 34548566433 scopus 로고    scopus 로고
    • Lin SQ, Wang SZ, Lin ZB and Lin YX. Purification and identification of glycopeptides from Ganoderma lucidum fruit bodies cultivated with grass and wood log. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 109-114.
  • 86
    • 2942564961 scopus 로고    scopus 로고
    • Effect of Ganoderma lucidum polysaccharides B on TNF-α and INF-γ production and their mRNA expression
    • Zhang Q.H., and Lin Z.B. Effect of Ganoderma lucidum polysaccharides B on TNF-α and INF-γ production and their mRNA expression. J Beijing Med Univ 31 (1999) 179-183
    • (1999) J Beijing Med Univ , vol.31 , pp. 179-183
    • Zhang, Q.H.1    Lin, Z.B.2
  • 87
    • 33748091693 scopus 로고    scopus 로고
    • Ganoderma - A therapeutic fungal biofactory
    • Russell R., and Paterson M. Ganoderma - A therapeutic fungal biofactory. Phytochem 67 (2006) 1985-2001
    • (2006) Phytochem , vol.67 , pp. 1985-2001
    • Russell, R.1    Paterson, M.2
  • 88
    • 0015048265 scopus 로고
    • Antitumor polysaccharides from some Polyporaceae, Ganoderma applanatum (Pers.) Pat. and Phellinus linteus (Berk. Et Curt) Aoshima
    • Sasaki T., Arai Y., Ikekawa T., Chihara G., and Fukuoka F. Antitumor polysaccharides from some Polyporaceae, Ganoderma applanatum (Pers.) Pat. and Phellinus linteus (Berk. Et Curt) Aoshima. Chem Pharm Bull 19 (1971) 821-826
    • (1971) Chem Pharm Bull , vol.19 , pp. 821-826
    • Sasaki, T.1    Arai, Y.2    Ikekawa, T.3    Chihara, G.4    Fukuoka, F.5
  • 89
    • 0011185059 scopus 로고
    • In vivo antitumor effect of crude extracts from the mycelium of Ganoderma lucidum
    • Lee S.S., Chen F.D., Chang S.C., Wei Y.H., Liu I., and Chen C. In vivo antitumor effect of crude extracts from the mycelium of Ganoderma lucidum. Bull Chinese Oncol Soc 5 (1984) 22-27
    • (1984) Bull Chinese Oncol Soc , vol.5 , pp. 22-27
    • Lee, S.S.1    Chen, F.D.2    Chang, S.C.3    Wei, Y.H.4    Liu, I.5    Chen, C.6
  • 90
    • 0001989380 scopus 로고
    • The inhibitory effect on artificial pulmonary metastasis of murine S-180 Sarcoma cells by orally administered Ganoderma lucidum
    • Hwang S.F., Liu K.J., Kuan Y.H., Tung K.S., Su C.H., and Tung T.C. The inhibitory effect on artificial pulmonary metastasis of murine S-180 Sarcoma cells by orally administered Ganoderma lucidum. J Chim Oncol Soc 5 (1989) 10-15
    • (1989) J Chim Oncol Soc , vol.5 , pp. 10-15
    • Hwang, S.F.1    Liu, K.J.2    Kuan, Y.H.3    Tung, K.S.4    Su, C.H.5    Tung, T.C.6
  • 91
    • 0026486158 scopus 로고
    • Antitumor activity of Ganoderma lucidum, and edible mushroom, on intraperitoneally implanted Lewis lung carcinoma in synergeneic mice
    • Furusawa E., Chou S.C., Furasawa S., Hirazum A., and Dang Y. Antitumor activity of Ganoderma lucidum, and edible mushroom, on intraperitoneally implanted Lewis lung carcinoma in synergeneic mice. Phytother Res 6 (1992) 300-304
    • (1992) Phytother Res , vol.6 , pp. 300-304
    • Furusawa, E.1    Chou, S.C.2    Furasawa, S.3    Hirazum, A.4    Dang, Y.5
  • 92
    • 0001185966 scopus 로고    scopus 로고
    • The antitumor activity of Ganoderma lucidum (Curt,:Fr.) P. Karst. (Lingzhi) (Aphylophoromycetidae) polysaccharides is related to tumor necrosis factor-α and interferon-γ
    • Zhang Q., and Lin Z.B. The antitumor activity of Ganoderma lucidum (Curt,:Fr.) P. Karst. (Lingzhi) (Aphylophoromycetidae) polysaccharides is related to tumor necrosis factor-α and interferon-γ. Int J Med Mushroom 1 (1999) 207-215
    • (1999) Int J Med Mushroom , vol.1 , pp. 207-215
    • Zhang, Q.1    Lin, Z.B.2
  • 93
    • 0036483993 scopus 로고    scopus 로고
    • Prevention of development of N,N′-dimethylhydrazine-induced colon tumors by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male ICR mice
    • Lu H., Kyo E., Uesaka T., Katoh O., and Watanabe H. Prevention of development of N,N′-dimethylhydrazine-induced colon tumors by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male ICR mice. Int J Mol Med 9 (2002) 113-117
    • (2002) Int J Mol Med , vol.9 , pp. 113-117
    • Lu, H.1    Kyo, E.2    Uesaka, T.3    Katoh, O.4    Watanabe, H.5
  • 94
    • 0037190124 scopus 로고    scopus 로고
    • Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum
    • Liu X., Yuan J.P., Chuang C.K., and Chen X.J. Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum. Cancer Lett 182 (2002) 155-161
    • (2002) Cancer Lett , vol.182 , pp. 155-161
    • Liu, X.1    Yuan, J.P.2    Chuang, C.K.3    Chen, X.J.4
  • 95
    • 0038148425 scopus 로고    scopus 로고
    • A water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia suppresses azoxymethane-induction of colon cancers in male F344 rats
    • Lu H., Kyo E., Uesaka T., Katoh O., and Watanabe H. A water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia suppresses azoxymethane-induction of colon cancers in male F344 rats. Oncol Rep 10 (2003) 375-379
    • (2003) Oncol Rep , vol.10 , pp. 375-379
    • Lu, H.1    Kyo, E.2    Uesaka, T.3    Katoh, O.4    Watanabe, H.5
  • 96
    • 0032964985 scopus 로고    scopus 로고
    • Polysaccharides isolated from mycelia of Ganoderma lucidum induced HL-60 cell apoptosis by enhancing macrophage activity
    • Hu Y.H., and Lin Z.B. Polysaccharides isolated from mycelia of Ganoderma lucidum induced HL-60 cell apoptosis by enhancing macrophage activity. Chin Pharmacol Bull 5 (1999) 27-30
    • (1999) Chin Pharmacol Bull , vol.5 , pp. 27-30
    • Hu, Y.H.1    Lin, Z.B.2
  • 97
    • 0000782680 scopus 로고    scopus 로고
    • Effects of polysaccharides isolated from mycelia of Ganoderma lucidum on HL-60 cell apoptosis
    • Hu Y.H., and Lin Z.B. Effects of polysaccharides isolated from mycelia of Ganoderma lucidum on HL-60 cell apoptosis. Acta Pharm Sin 34 (1999) 268-271
    • (1999) Acta Pharm Sin , vol.34 , pp. 268-271
    • Hu, Y.H.1    Lin, Z.B.2
  • 100
    • 34548589730 scopus 로고    scopus 로고
    • Lei LS, Li MC and Sun LS. Ganoderma lucidum and its components on the function of macrophages. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 20-23.
  • 102
    • 0030935175 scopus 로고    scopus 로고
    • The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocyes
    • Wang S.Y., Hsu M.L., Hsu H.C., Tzeng C.H., Lee S.S., Shiao M.S., and Ho C.K. The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocyes. Int J Cancer 70 (1997) 699-705
    • (1997) Int J Cancer , vol.70 , pp. 699-705
    • Wang, S.Y.1    Hsu, M.L.2    Hsu, H.C.3    Tzeng, C.H.4    Lee, S.S.5    Shiao, M.S.6    Ho, C.K.7
  • 103
    • 0001185966 scopus 로고    scopus 로고
    • The antitumor activity of Ganoderma lucidum (Curt; Fr.) P. Karst (Ling Zhi) (Aphyllophoromycetideae) polysaccharides is related to tumor necrosis factor-α and interferon-γ
    • Zhang Q.H., and Lin Z.B. The antitumor activity of Ganoderma lucidum (Curt; Fr.) P. Karst (Ling Zhi) (Aphyllophoromycetideae) polysaccharides is related to tumor necrosis factor-α and interferon-γ. Int J Med Mushroom 1 (1999) 207-215
    • (1999) Int J Med Mushroom , vol.1 , pp. 207-215
    • Zhang, Q.H.1    Lin, Z.B.2
  • 104
    • 34548576384 scopus 로고    scopus 로고
    • Ganoderma lucidum (W.Curt.:Fr.) Lloyd and G. applanatum (Pers.) Pat. (Aphyllophoromycetideae) from Slovenian habitats: cultivation, isolation, and testing of active compounds
    • Boh B., Berovic M., Wraber B., Hodzar D., Habijanic J., Pohleven F., and Zore I. Ganoderma lucidum (W.Curt.:Fr.) Lloyd and G. applanatum (Pers.) Pat. (Aphyllophoromycetideae) from Slovenian habitats: cultivation, isolation, and testing of active compounds. Int J Medic Mushroom 6 (2004) 15-32
    • (2004) Int J Medic Mushroom , vol.6 , pp. 15-32
    • Boh, B.1    Berovic, M.2    Wraber, B.3    Hodzar, D.4    Habijanic, J.5    Pohleven, F.6    Zore, I.7
  • 105
    • 34548594719 scopus 로고    scopus 로고
    • Lee SS, Lee PL, Chen CF, Wang SY and Chen KY. Antitumor effects of Ganoderma lucidum. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 46-57.
  • 106
    • 34548568422 scopus 로고    scopus 로고
    • Cao LZ and Lin ZB. Regulation of Ganoderma lucidum polysaccharides on cytotoxic T lymphocytes induced by dendric cells in vitro. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 122-129.
  • 107
    • 0027384759 scopus 로고
    • Antagonistic effect of Ganoderma lucidum polysaccharide on the immunosuppressive response induced by cyclosporin A, hydrocortisone and antitumor agents
    • Lei L., Lin Z., Chen Q., Li R., and He Y. Antagonistic effect of Ganoderma lucidum polysaccharide on the immunosuppressive response induced by cyclosporin A, hydrocortisone and antitumor agents. Chin J Pharmacol Toxicol 7 (1993) 183-185
    • (1993) Chin J Pharmacol Toxicol , vol.7 , pp. 183-185
    • Lei, L.1    Lin, Z.2    Chen, Q.3    Li, R.4    He, Y.5
  • 108
    • 0033392969 scopus 로고    scopus 로고
    • Effect of Ganoderma polysaccharide on intracellular free calcium in murine peritoneal macrophages
    • Li M., Lei L., and Liang D. Effect of Ganoderma polysaccharide on intracellular free calcium in murine peritoneal macrophages. Chin Pharm J 34 (1999) 805-807
    • (1999) Chin Pharm J , vol.34 , pp. 805-807
    • Li, M.1    Lei, L.2    Liang, D.3
  • 109
    • 0036771690 scopus 로고    scopus 로고
    • Regulation on maturation and function of dendritic cells by Ganoderma lucidum polysaccharides
    • Cao L.Z., and Lin Z.B. Regulation on maturation and function of dendritic cells by Ganoderma lucidum polysaccharides. Immunol Lett 83 (2002) 163-169
    • (2002) Immunol Lett , vol.83 , pp. 163-169
    • Cao, L.Z.1    Lin, Z.B.2
  • 110
    • 0037385404 scopus 로고    scopus 로고
    • Regulation effect of Ganoderma lucidum polysaccharides on cytotoxic T-lymphocytes induced by dendritic cells in vitro
    • Cao L.Z., and Lin Z.B. Regulation effect of Ganoderma lucidum polysaccharides on cytotoxic T-lymphocytes induced by dendritic cells in vitro. Acta Pharmacol Sin 24 (2003) 321-326
    • (2003) Acta Pharmacol Sin , vol.24 , pp. 321-326
    • Cao, L.Z.1    Lin, Z.B.2
  • 111
  • 113
    • 0000202747 scopus 로고
    • Effects of Ganoderma polysaccharides on the activity of DNA polymerase in spleen cells stimulated by alloantigents in mice in vitro
    • Lei L.S., and Lin Z.B. Effects of Ganoderma polysaccharides on the activity of DNA polymerase in spleen cells stimulated by alloantigents in mice in vitro. J Beijing Med Univ 23 (1991) 329-333
    • (1991) J Beijing Med Univ , vol.23 , pp. 329-333
    • Lei, L.S.1    Lin, Z.B.2
  • 114
    • 8544243187 scopus 로고
    • Effects of Ganoderma polysaccharides on the MLC reaction
    • Lei L.S., and Lin Z.B. Effects of Ganoderma polysaccharides on the MLC reaction. Basic Med Clin 12 (1992) 59-60
    • (1992) Basic Med Clin , vol.12 , pp. 59-60
    • Lei, L.S.1    Lin, Z.B.2
  • 115
    • 2142691734 scopus 로고    scopus 로고
    • Comparison of the effects of polysaccharides from wood-cultured and bag-cultured Ganoderma lucidum on murine spleen lymphocyte proliferation in vitro
    • Cao L.Z., and Lin Z.B. Comparison of the effects of polysaccharides from wood-cultured and bag-cultured Ganoderma lucidum on murine spleen lymphocyte proliferation in vitro. Acta Pharmacol Sin 38 (2003) 92-97
    • (2003) Acta Pharmacol Sin , vol.38 , pp. 92-97
    • Cao, L.Z.1    Lin, Z.B.2
  • 116
    • 0037203554 scopus 로고    scopus 로고
    • Structural features of immunologically active polysaccharides from Ganoderma lucidum
    • Bao X.F., Wang X.S., Dong Q., Fang J.N., and Li X.Y. Structural features of immunologically active polysaccharides from Ganoderma lucidum. Phytochem 59 (2002) 175-181
    • (2002) Phytochem , vol.59 , pp. 175-181
    • Bao, X.F.1    Wang, X.S.2    Dong, Q.3    Fang, J.N.4    Li, X.Y.5
  • 117
    • 0037189172 scopus 로고    scopus 로고
    • Activation of B lymphocytes by GLIS, a bioactive proteoglycan from Ganoderma lucidum
    • Zhang J.S., Tang Q.J., Zimmerman-Kordmann M., Reuter W., and Fan H. Activation of B lymphocytes by GLIS, a bioactive proteoglycan from Ganoderma lucidum. Life Sci 71 (2002) 623-638
    • (2002) Life Sci , vol.71 , pp. 623-638
    • Zhang, J.S.1    Tang, Q.J.2    Zimmerman-Kordmann, M.3    Reuter, W.4    Fan, H.5
  • 118
    • 0347024380 scopus 로고    scopus 로고
    • Effectiveness of Dp2 nasal therapy for Dp2-induced airway inflammation in mice: using oral Ganoderma lucidum as an immunomodulator
    • Liu Y.H., Tsai C.F., Kao M.C., Lai Y.L., and Tsai J.J. Effectiveness of Dp2 nasal therapy for Dp2-induced airway inflammation in mice: using oral Ganoderma lucidum as an immunomodulator. J Microbiol Immunol Infect 36 (2003) 236-242
    • (2003) J Microbiol Immunol Infect , vol.36 , pp. 236-242
    • Liu, Y.H.1    Tsai, C.F.2    Kao, M.C.3    Lai, Y.L.4    Tsai, J.J.5
  • 119
    • 34548579672 scopus 로고    scopus 로고
    • The Pharmacological Study of Ganoderma Spores and Its Active Components
    • Lin Z.B., and Wang P.Y. The Pharmacological Study of Ganoderma Spores and Its Active Components. J Peking Univ (Health Sciences) 38 5 (2006) 541-547
    • (2006) J Peking Univ (Health Sciences) , vol.38 , Issue.5 , pp. 541-547
    • Lin, Z.B.1    Wang, P.Y.2
  • 120
    • 34548599143 scopus 로고    scopus 로고
    • Study on mechanism of Ganodermaa lucidum polysaccharides enhancing activity of LAK cells from human cord blood
    • Xu X., Hou G.H., Cao R.H., and Xie W.G. Study on mechanism of Ganodermaa lucidum polysaccharides enhancing activity of LAK cells from human cord blood. Chinese J Cancer Biotherapy 4 (1997) 236
    • (1997) Chinese J Cancer Biotherapy , vol.4 , pp. 236
    • Xu, X.1    Hou, G.H.2    Cao, R.H.3    Xie, W.G.4
  • 121
    • 8544228336 scopus 로고    scopus 로고
    • Lin ZB and Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin 2004;25:1387-1391.
  • 122
    • 0028103808 scopus 로고
    • A novel population of expended human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency
    • Lu P.H., and Negrin R.S. A novel population of expended human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency. J Immunol 153 (1994) 1687-1696
    • (1994) J Immunol , vol.153 , pp. 1687-1696
    • Lu, P.H.1    Negrin, R.S.2
  • 123
    • 24744436387 scopus 로고    scopus 로고
    • Effects of Ganoderma lucidum polysaccharides on proliferation and cytotoxicity of cytokine-induced killer cells
    • Zhu X.L., and Lin Z.B. Effects of Ganoderma lucidum polysaccharides on proliferation and cytotoxicity of cytokine-induced killer cells. Acta Pharm Sin 26 (2005) 1130-1137
    • (2005) Acta Pharm Sin , vol.26 , pp. 1130-1137
    • Zhu, X.L.1    Lin, Z.B.2
  • 124
    • 31344435686 scopus 로고    scopus 로고
    • Modulation of cytokines production, granzyme B and perforin in murine CIK cells by Ganoderma lucidum polysaccharides
    • Zhu X.L., and Lin Z.B. Modulation of cytokines production, granzyme B and perforin in murine CIK cells by Ganoderma lucidum polysaccharides. Carbohyd Polym 63 (2006) 188-197
    • (2006) Carbohyd Polym , vol.63 , pp. 188-197
    • Zhu, X.L.1    Lin, Z.B.2
  • 125
    • 0036169299 scopus 로고    scopus 로고
    • Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and protewmic analyses of a fucose-containing glycoprotein fraction responsible for the activities
    • Wang Y.Y., Khoo K.H., Chen S.T., Lin C.C., Wong C.H., and Lin C.H. Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and protewmic analyses of a fucose-containing glycoprotein fraction responsible for the activities. Bioorg Med Chem 10 (2002) 1057-1062
    • (2002) Bioorg Med Chem , vol.10 , pp. 1057-1062
    • Wang, Y.Y.1    Khoo, K.H.2    Chen, S.T.3    Lin, C.C.4    Wong, C.H.5    Lin, C.H.6
  • 126
    • 4644356961 scopus 로고    scopus 로고
    • Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides
    • Chen H.S., Tsai Y.F., Lin S., Lin C.C., Khoo K.H., Lin C.H., and Wong C.H. Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides. Bioorg Med Chem 12 (2004) 5595-5601
    • (2004) Bioorg Med Chem , vol.12 , pp. 5595-5601
    • Chen, H.S.1    Tsai, Y.F.2    Lin, S.3    Lin, C.C.4    Khoo, K.H.5    Lin, C.H.6    Wong, C.H.7
  • 127
    • 4644349586 scopus 로고    scopus 로고
    • Hepatotoxicity due to a formulation of Ganoderma lucidum (lingzhi). Letters to the editor
    • Yuen M.F., Ip P., Ng W.K., and Lai C.L. Hepatotoxicity due to a formulation of Ganoderma lucidum (lingzhi). Letters to the editor. J Hepatol 41 (2004) 685-690
    • (2004) J Hepatol , vol.41 , pp. 685-690
    • Yuen, M.F.1    Ip, P.2    Ng, W.K.3    Lai, C.L.4
  • 128
    • 34548592670 scopus 로고    scopus 로고
    • Effect of various grades of Ganoderma lucidum on tumor inhibition and immunostimulation
    • Wang X.X., Tang Q.J., Zhang J.S., Yang Y., Liu Y.F., Jia W., and Liu F. Effect of various grades of Ganoderma lucidum on tumor inhibition and immunostimulation. Acta Edul Fung 12 (2005) 48-51
    • (2005) Acta Edul Fung , vol.12 , pp. 48-51
    • Wang, X.X.1    Tang, Q.J.2    Zhang, J.S.3    Yang, Y.4    Liu, Y.F.5    Jia, W.6    Liu, F.7
  • 129
    • 34548565166 scopus 로고    scopus 로고
    • Comparison of bioactivity of fruiting body and mycelia of Ganoderma lucidum and their purified fractions
    • Zhang J.S., Jia W., Xing Z.T., Tang Q.J., Liu Y.F., Yang Y., Zhou C.Y., and Liu F. Comparison of bioactivity of fruiting body and mycelia of Ganoderma lucidum and their purified fractions. Mycosystema 23 (2004) 85-92
    • (2004) Mycosystema , vol.23 , pp. 85-92
    • Zhang, J.S.1    Jia, W.2    Xing, Z.T.3    Tang, Q.J.4    Liu, Y.F.5    Yang, Y.6    Zhou, C.Y.7    Liu, F.8
  • 130
    • 2942539575 scopus 로고    scopus 로고
    • Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide
    • Cao Q.Z., and Lin Z.B. Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide. Acta Pharmacol Sin 25 (2004) 833-838
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 833-838
    • Cao, Q.Z.1    Lin, Z.B.2
  • 131
    • 32544457890 scopus 로고    scopus 로고
    • Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell
    • Cao Q.Z., and Lin Z.B. Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell. Life Sci 78 (2006) 1457-1463
    • (2006) Life Sci , vol.78 , pp. 1457-1463
    • Cao, Q.Z.1    Lin, Z.B.2
  • 132
    • 0346492926 scopus 로고    scopus 로고
    • Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum
    • Song Y.S., Kim S.H., Sa J.H., Jin C., Lim C.L., and Park E.H. Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum. J Ethnopharmacol 90 (2004) 17-20
    • (2004) J Ethnopharmacol , vol.90 , pp. 17-20
    • Song, Y.S.1    Kim, S.H.2    Sa, J.H.3    Jin, C.4    Lim, C.L.5    Park, E.H.6
  • 133
    • 15444362990 scopus 로고    scopus 로고
    • Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-β1 from prostate cancer cells
    • Stanley G., Harvey K., Slivova V., Jiang J., and Sliva D. Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-β1 from prostate cancer cells. Biochem Biophys Res Com 330 (2005) 46-52
    • (2005) Biochem Biophys Res Com , vol.330 , pp. 46-52
    • Stanley, G.1    Harvey, K.2    Slivova, V.3    Jiang, J.4    Sliva, D.5
  • 134
    • 0036712254 scopus 로고    scopus 로고
    • You YH and Lin ZB. Protective effects of Ganoderma lucidum polysaccharides peptide on injury of macrophages induced by reactive oxygen species. Acta Pharmacol Sin 2002;23:878-891.
  • 136
    • 0042572432 scopus 로고    scopus 로고
    • In vitro and in vivo protective effect of Ganoderma lucidum polysaccharides on alloxan-induced pancreatic islets damage
    • Zhang H.N., He J.H., Yuan L., and Lin Z.B. In vitro and in vivo protective effect of Ganoderma lucidum polysaccharides on alloxan-induced pancreatic islets damage. Life Sci 73 (2003) 2307-2319
    • (2003) Life Sci , vol.73 , pp. 2307-2319
    • Zhang, H.N.1    He, J.H.2    Yuan, L.3    Lin, Z.B.4
  • 137
    • 33747339762 scopus 로고    scopus 로고
    • Antimutagenic activity of methanolic extract of Ganoderma lucidum and its effect on hepatic damage caused by benzo[a]pyrene
    • Lakshmi B., Ajith T.A., Jose N., and Janardhanan K.K. Antimutagenic activity of methanolic extract of Ganoderma lucidum and its effect on hepatic damage caused by benzo[a]pyrene. J Ethnopharmacol 107 (2006) 297-303
    • (2006) J Ethnopharmacol , vol.107 , pp. 297-303
    • Lakshmi, B.1    Ajith, T.A.2    Jose, N.3    Janardhanan, K.K.4
  • 139
    • 11144324311 scopus 로고    scopus 로고
    • Purification and characterization of a novel proteinase A inhibitor from Ganoderma lucidum by submerged fermentation
    • Tian Y.P., and Zhang K.C. Purification and characterization of a novel proteinase A inhibitor from Ganoderma lucidum by submerged fermentation. Enzyme Microb Technol 36 (2005) 357-361
    • (2005) Enzyme Microb Technol , vol.36 , pp. 357-361
    • Tian, Y.P.1    Zhang, K.C.2
  • 140
    • 7044225920 scopus 로고    scopus 로고
    • Possible mode of action of antiherpetic activities of a proteoglycan isolated from the mycelia of Ganoderma lucidum in vitro
    • Liu J., Yang F., Ye L.B., Yang X.J., Timani K.A., Zheng Y., and Wang Y.H. Possible mode of action of antiherpetic activities of a proteoglycan isolated from the mycelia of Ganoderma lucidum in vitro. J Ethnopharmacol 95 (2004) 256-272
    • (2004) J Ethnopharmacol , vol.95 , pp. 256-272
    • Liu, J.1    Yang, F.2    Ye, L.B.3    Yang, X.J.4    Timani, K.A.5    Zheng, Y.6    Wang, Y.H.7
  • 141
    • 0346374728 scopus 로고    scopus 로고
    • A distinctive ribonuclease from fresh fruiting bodies of the medicinal mushroom Ganoderma lucidum
    • Wang H.X., Ng T.B., and Chiu S.W. A distinctive ribonuclease from fresh fruiting bodies of the medicinal mushroom Ganoderma lucidum. Biochem Biophys Res Com 314 (2004) 519-522
    • (2004) Biochem Biophys Res Com , vol.314 , pp. 519-522
    • Wang, H.X.1    Ng, T.B.2    Chiu, S.W.3
  • 142
    • 30344431502 scopus 로고    scopus 로고
    • Ganodermin, an antifungal protein from fruiting bodies of the medicinal mushroom Ganoderma lucidum
    • Wang H.X., and Ng T.B. Ganodermin, an antifungal protein from fruiting bodies of the medicinal mushroom Ganoderma lucidum. Peptides 27 (2006) 27-30
    • (2006) Peptides , vol.27 , pp. 27-30
    • Wang, H.X.1    Ng, T.B.2
  • 145
    • 34548596102 scopus 로고    scopus 로고
    • Zhang CY and Li YM. Clinical investigation of Green Valley Lingzhi capsule on type 2 diabetes mellitus. In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 194-198.
  • 146
    • 34548579671 scopus 로고    scopus 로고
    • Shi KG and Quing LH. The follow-up observation assessment of medium and late phases cancer treated by Chinese Ganoderma lucidum essence (CGLE). In: Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Zhi-Bin Lin (ed), Proceedings of International Symposium on Ganoderma Research, Shanghai, October 21-23, 2002, Beijing, Medical University Press, pp. 188-193.
  • 148
    • 33748042041 scopus 로고    scopus 로고
    • Phase I study of a methanol extract of Ganoderma lucidum, edible and medicinal mushroom, in men with mild symptoms of bladder outlet obstruction
    • Noguchi M., Kakuma T., Tomiyasu K., Konishi F., Kumamoto S., Kondo R., and Matsuoka K. Phase I study of a methanol extract of Ganoderma lucidum, edible and medicinal mushroom, in men with mild symptoms of bladder outlet obstruction. Urology 66 suppl. 3A (2005) 21
    • (2005) Urology , vol.66 , Issue.SUPPL. 3A , pp. 21
    • Noguchi, M.1    Kakuma, T.2    Tomiyasu, K.3    Konishi, F.4    Kumamoto, S.5    Kondo, R.6    Matsuoka, K.7
  • 150
    • 0036671212 scopus 로고    scopus 로고
    • Regression of prostate cancer following administration of Genistein Combined Polysaccharide (GCP), a nutritional supplement: a case report
    • Ghafa M.A., Golliday E., Bingham J., Mansukhani M.M., Anastasiasis A.G., and Katz A.E. Regression of prostate cancer following administration of Genistein Combined Polysaccharide (GCP), a nutritional supplement: a case report. J Altern Complement Med 8 (2002) 493-497
    • (2002) J Altern Complement Med , vol.8 , pp. 493-497
    • Ghafa, M.A.1    Golliday, E.2    Bingham, J.3    Mansukhani, M.M.4    Anastasiasis, A.G.5    Katz, A.E.6
  • 151
    • 0041853581 scopus 로고    scopus 로고
    • Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients
    • Gao Y., Zhou S., Jiang W., Huang M., and Dai X. Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients. Immunol Invest 32 (2003) 201-215
    • (2003) Immunol Invest , vol.32 , pp. 201-215
    • Gao, Y.1    Zhou, S.2    Jiang, W.3    Huang, M.4    Dai, X.5
  • 152
    • 20844437053 scopus 로고    scopus 로고
    • Gao Y, Tang W, Dai X, Chen G, Ye J, Chen E, Koh HL, Li X, and Zhou S, Effects of water-soluble Ganoderma lucidum polysaccharides on the immune functions of patients with advanced lung cancer. J Med Food 2005;8:159-168.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.