-
1
-
-
84921047834
-
Alemtuzumab in the treatment of multiple sclerosis: Key clinical trial results and considerations for use
-
Havrdova, E.; Horakova, D.; Kovarova, I. Alemtuzumab in the treatment of multiple sclerosis: Key clinical trial results and considerations for use. Ther. Adv. Neurol. Disord. 2015, 8, 31–45.
-
(2015)
Ther. Adv. Neurol. Disord
, vol.8
, pp. 31-45
-
-
Havrdova, E.1
Horakova, D.2
Kovarova, I.3
-
2
-
-
84904020925
-
Alemtuzumab: The advantages and challenges of a novel therapy in MS
-
Menge, T.; Stuve, O.; Kieseier, B.C.; Hartung, H.P. Alemtuzumab: The advantages and challenges of a novel therapy in MS. Neurology 2014, 83, 87–97.
-
(2014)
Neurology
, vol.83
, pp. 87-97
-
-
Menge, T.1
Stuve, O.2
Kieseier, B.C.3
Hartung, H.P.4
-
3
-
-
84874948941
-
Multiple sclerosis: Reprogramming the immune repertoire with alemtuzumab in MS
-
Wiendl, H.; Kieseier, B. Multiple sclerosis: Reprogramming the immune repertoire with alemtuzumab in MS. Nat. Rev. Neurol. 2013, 9, 125–126.
-
(2013)
Nat. Rev. Neurol
, vol.9
, pp. 125-126
-
-
Wiendl, H.1
Kieseier, B.2
-
4
-
-
0021713342
-
Production of functional chimaeric mouse/human antibody
-
Boulianne, G.L.; Hozumi, N.; Shulman, M.J. Production of functional chimaeric mouse/human antibody. Nature 1984, 312, 643–646.
-
(1984)
Nature
, vol.312
, pp. 643-646
-
-
Boulianne, G.L.1
Hozumi, N.2
Shulman, M.J.3
-
5
-
-
84856252354
-
Immune mechanisms of new therapeutic strategies in multiple sclerosis—A focus on alemtuzumab
-
Klotz, L.; Meuth, S.G.; Wiendl, H. Immune mechanisms of new therapeutic strategies in multiple sclerosis—A focus on alemtuzumab. Clin. Immunol. 2012, 142, 25–30.
-
(2012)
Clin. Immunol
, vol.142
, pp. 25-30
-
-
Klotz, L.1
Meuth, S.G.2
Wiendl, H.3
-
6
-
-
33845786517
-
Heterogeneous CD52 expression among hematologic neoplasms: Implications for the use of alemtuzumab (Campath-1H)
-
Rodig, S.J.; Abramson, J.S.; Pinkus, G.S.; Treon, S.P.; Dorfman, D.M.; Dong, H.Y.; Shipp, M.A.; Kutok, J.L. Heterogeneous CD52 expression among hematologic neoplasms: Implications for the use of alemtuzumab (Campath-1H). Clin. Cancer Res. 2006, 12, 7174–7179.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 7174-7179
-
-
Rodig, S.J.1
Abramson, J.S.2
Pinkus, G.S.3
Treon, S.P.4
Dorfman, D.M.5
Dong, H.Y.6
Shipp, M.A.7
Kutok, J.L.8
-
7
-
-
0032005642
-
Levels of expression of CD52 in normal and leukemic B and T cells: Correlation with in vivo therapeutic responses to Campath-1H
-
Ginaldi, L.; de Martinis, M.; Matutes, E.; Farahat, N.; Morilla, R.; Dyer, M.J.; Catovsky, D. Levels of expression of CD52 in normal and leukemic B and T cells: Correlation with in vivo therapeutic responses to Campath-1H. Leuk. Res. 1998, 22, 185–191.
-
(1998)
Leuk. Res
, vol.22
, pp. 185-191
-
-
Ginaldi, L.1
de Martinis, M.2
Matutes, E.3
Farahat, N.4
Morilla, R.5
Dyer, M.J.6
Catovsky, D.7
-
8
-
-
0034765991
-
The CD52 antigen and development of the Campath antibodies
-
Hale, G. The CD52 antigen and development of the Campath antibodies. Cytotherapy 2001, 3, 137–143.
-
(2001)
Cytotherapy
, vol.3
, pp. 137-143
-
-
Hale, G.1
-
9
-
-
0025878925
-
Characterization of the Campath-1 (CDw52) antigen: Biochemical analysis and cDNA cloning reveal an unusually small peptide backbone
-
Xia, M.Q.; Tone, M.; Packman, L.; Hale, G.; Waldmann, H. Characterization of the Campath-1 (CDw52) antigen: Biochemical analysis and cDNA cloning reveal an unusually small peptide backbone. Eur. J. Immunol. 1991, 21, 1677–1684.
-
(1991)
Eur. J. Immunol
, vol.21
, pp. 1677-1684
-
-
Xia, M.Q.1
Tone, M.2
Packman, L.3
Hale, G.4
Waldmann, H.5
-
10
-
-
0028870425
-
Cross-linking of the Campath-1 antigen (CD52) triggers activation of normal human T lymphocytes
-
Rowan, W.C.; Hale, G.; Tite, J.P.; Brett, S.J. Cross-linking of the Campath-1 antigen (CD52) triggers activation of normal human T lymphocytes. Int. Immunol. 1995, 7, 69–77.
-
(1995)
Int. Immunol
, vol.7
, pp. 69-77
-
-
Rowan, W.C.1
Hale, G.2
Tite, J.P.3
Brett, S.J.4
-
11
-
-
0033559731
-
Characterization of the 4C8 antigen involved in transendothelial migration of CD26(Hi) T cells after tight adhesion to human umbilical vein endothelial cell monolayers
-
Masuyama, J.; Yoshio, T.; Suzuki, K.; Kitagawa, S.; Iwamoto, M.; Kamimura, T.; Hirata, D.; Takeda, A.; Kano, S.; Minota, S. Characterization of the 4C8 antigen involved in transendothelial migration of CD26(hi) T cells after tight adhesion to human umbilical vein endothelial cell monolayers. J. Exp. Med. 1999, 189, 979–990.
-
(1999)
J. Exp. Med
, vol.189
, pp. 979-990
-
-
Masuyama, J.1
Yoshio, T.2
Suzuki, K.3
Kitagawa, S.4
Iwamoto, M.5
Kamimura, T.6
Hirata, D.7
Takeda, A.8
Kano, S.9
Minota, S.10
-
12
-
-
33746836125
-
CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells
-
Watanabe, T.; Masuyama, J.; Sohma, Y.; Inazawa, H.; Horie, K.; Kojima, K.; Uemura, Y.; Aoki, Y.; Kaga, S.; Minota, S., et al. CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells. Clin. Immunol. 2006, 120, 247–259.
-
(2006)
Clin. Immunol
, vol.120
, pp. 247-259
-
-
Watanabe, T.1
Masuyama, J.2
Sohma, Y.3
Inazawa, H.4
Horie, K.5
Kojima, K.6
Uemura, Y.7
Aoki, Y.8
Kaga, S.9
Minota, S.10
-
13
-
-
84879365270
-
T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10
-
Bandala-Sanchez, E.; Zhang, Y.; Reinwald, S.; Dromey, J.A.; Lee, B.H.; Qian, J.; Bohmer, R.M.; Harrison, L.C. T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10. Nat. Immunol. 2013, 14, 741–748.
-
(2013)
Nat. Immunol
, vol.14
, pp. 741-748
-
-
Bandala-Sanchez, E.1
Zhang, Y.2
Reinwald, S.3
Dromey, J.A.4
Lee, B.H.5
Qian, J.6
Bohmer, R.M.7
Harrison, L.C.8
-
14
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy, K.J.; Powrie, F. Regulatory T cells in the control of immune pathology. Nat. Immunol. 2001, 2, 816–822.
-
(2001)
Nat. Immunol
, vol.2
, pp. 816-822
-
-
Maloy, K.J.1
Powrie, F.2
-
15
-
-
80052649553
-
CD4+FoxP3+ T regulatory cells in human autoimmunity: More than a numbers game
-
Long, S.A.; Buckner, J.H. CD4+FoxP3+ T regulatory cells in human autoimmunity: More than a numbers game. J. Immunol. 2011, 187, 2061–2066.
-
(2011)
J. Immunol
, vol.187
, pp. 2061-2066
-
-
Long, S.A.1
Buckner, J.H.2
-
16
-
-
84921319094
-
Alemtuzumab treatment of multiple sclerosis: Long-term safety and efficacy
-
Tuohy, O.; Costelloe, L.; Hill-Cawthorne, G.; Bjornson, I.; Harding, K.; Robertson, N.; May, K.; Button, T.; Azzopardi, L.; Kousin-Ezewu, O., et al. Alemtuzumab treatment of multiple sclerosis: Long-term safety and efficacy. J. Neurol. Neurosurg. Psychiatry 2015, 86, 208–215.
-
(2015)
J. Neurol. Neurosurg. Psychiatry
, vol.86
, pp. 208-215
-
-
Tuohy, O.1
Costelloe, L.2
Hill-Cawthorne, G.3
Bjornson, I.4
Harding, K.5
Robertson, N.6
May, K.7
Button, T.8
Azzopardi, L.9
Kousin-Ezewu, O.10
-
17
-
-
84862677418
-
Human peripheral blood mononuclear cells exhibit heterogeneous CD52 expression levels and show differential sensitivity to alemtuzumab mediated cytolysis
-
Rao, S.P.; Sancho, J.; Campos-Rivera, J.; Boutin, P.M.; Severy, P.B.; Weeden, T.; Shankara, S.; Roberts, B.L.; Kaplan, J.M. Human peripheral blood mononuclear cells exhibit heterogeneous CD52 expression levels and show differential sensitivity to alemtuzumab mediated cytolysis. PLoS ONE 2012, 7, e39416.
-
(2012)
Plos ONE
, vol.7
-
-
Rao, S.P.1
Sancho, J.2
Campos-Rivera, J.3
Boutin, P.M.4
Severy, P.B.5
Weeden, T.6
Shankara, S.7
Roberts, B.L.8
Kaplan, J.M.9
-
18
-
-
69949120991
-
Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model
-
Hu, Y.; Turner, M.J.; Shields, J.; Gale, M.S.; Hutto, E.; Roberts, B.L.; Siders, W.M.; Kaplan, J.M. Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model. Immunology 2009, 128, 260–270.
-
(2009)
Immunology
, vol.128
, pp. 260-270
-
-
Hu, Y.1
Turner, M.J.2
Shields, J.3
Gale, M.S.4
Hutto, E.5
Roberts, B.L.6
Siders, W.M.7
Kaplan, J.M.8
-
19
-
-
84907260470
-
Alemtuzumab for the treatment of relapsing-remitting multiple sclerosis: A review of its clinical pharmacology, efficacy and safety
-
Jones, D.E.; Goldman, M.D. Alemtuzumab for the treatment of relapsing-remitting multiple sclerosis: A review of its clinical pharmacology, efficacy and safety. Expert Rev. Clin. Immunol. 2014, 10, 1281–1291.
-
(2014)
Expert Rev. Clin. Immunol
, vol.10
, pp. 1281-1291
-
-
Jones, D.E.1
Goldman, M.D.2
-
20
-
-
31544467633
-
The window of therapeutic opportunity in multiple sclerosis: Evidence from monoclonal antibody therapy
-
Coles, A.J.; Cox, A.; Le Page, E.; Jones, J.; Trip, S.A.; Deans, J.; Seaman, S.; Miller, D.H.; Hale, G.; Waldmann, H., et al. The window of therapeutic opportunity in multiple sclerosis: Evidence from monoclonal antibody therapy. J. Neurol. 2006, 253, 98–108.
-
(2006)
J. Neurol
, vol.253
, pp. 98-108
-
-
Coles, A.J.1
Cox, A.2
Le Page, E.3
Jones, J.4
Trip, S.A.5
Deans, J.6
Seaman, S.7
Miller, D.H.8
Hale, G.9
Waldmann, H.10
-
21
-
-
77249114139
-
B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis
-
Thompson, S.A.; Jones, J.L.; Cox, A.L.; Compston, D.A.; Coles, A.J. B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis. J. Clin. Immunol. 2010, 30, 99–105.
-
(2010)
J. Clin. Immunol
, vol.30
, pp. 99-105
-
-
Thompson, S.A.1
Jones, J.L.2
Cox, A.L.3
Compston, D.A.4
Coles, A.J.5
-
22
-
-
68849084141
-
IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H)
-
Jones, J.L.; Phuah, C.L.; Cox, A.L.; Thompson, S.A.; Ban, M.; Shawcross, J.; Walton, A.; Sawcer, S.J.; Compston, A.; Coles, A.J. IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H). J. Clin. Investig. 2009, 119, 2052–2061.
-
(2009)
J. Clin. Investig
, vol.119
, pp. 2052-2061
-
-
Jones, J.L.1
Phuah, C.L.2
Cox, A.L.3
Thompson, S.A.4
Ban, M.5
Shawcross, J.6
Walton, A.7
Sawcer, S.J.8
Compston, A.9
Coles, A.J.10
-
23
-
-
0032882173
-
Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis
-
Coles, A.J.; Wing, M.G.; Molyneux, P.; Paolillo, A.; Davie, C.M.; Hale, G.; Miller, D.; Waldmann, H.; Compston, A. Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis. Ann. Neurol. 1999, 46, 296–304.
-
(1999)
Ann. Neurol
, vol.46
, pp. 296-304
-
-
Coles, A.J.1
Wing, M.G.2
Molyneux, P.3
Paolillo, A.4
Davie, C.M.5
Hale, G.6
Miller, D.7
Waldmann, H.8
Compston, A.9
-
24
-
-
54949143968
-
Alemtuzumab vs. Interferon β-1a in early multiple sclerosis
-
Investigators, C.T.; Coles, A.J.; Compston, D.A.; Selmaj, K.W.; Lake, S.L.; Moran, S.; Margolin, D.H.; Norris, K.; Tandon, P.K. Alemtuzumab vs. Interferon β-1a in early multiple sclerosis. N. Engl. J. Med. 2008, 359, 1786–1801.
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 1786-1801
-
-
Investigators, C.T.1
Coles, A.J.2
Compston, D.A.3
Selmaj, K.W.4
Lake, S.L.5
Moran, S.6
Margolin, D.H.7
Norris, K.8
Tandon, P.K.9
-
25
-
-
79952740129
-
Alemtuzumab versus interferon β-1a in early relapsing-remitting multiple sclerosis: Post-hoc and subset analyses of clinical efficacy outcomes
-
Coles, A.J.; Fox, E.; Vladic, A.; Gazda, S.K.; Brinar, V.; Selmaj, K.W.; Bass, A.D.; Wynn, D.R.; Margolin, D.H.; Lake, S.L., et al. Alemtuzumab versus interferon β-1a in early relapsing-remitting multiple sclerosis: Post-hoc and subset analyses of clinical efficacy outcomes. Lancet Neurol. 2011, 10, 338–348.
-
(2011)
Lancet Neurol
, vol.10
, pp. 338-348
-
-
Coles, A.J.1
Fox, E.2
Vladic, A.3
Gazda, S.K.4
Brinar, V.5
Selmaj, K.W.6
Bass, A.D.7
Wynn, D.R.8
Margolin, D.H.9
Lake, S.L.10
-
26
-
-
84869492471
-
Alemtuzumab versus interferon β 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: A randomised controlled phase 3 trial
-
Cohen, J.A.; Coles, A.J.; Arnold, D.L.; Confavreux, C.; Fox, E.J.; Hartung, H.P.; Havrdova, E.; Selmaj, K.W.; Weiner, H.L.; Fisher, E., et al. Alemtuzumab versus interferon β 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: A randomised controlled phase 3 trial. Lancet 2012, 380, 1819–1828.
-
(2012)
Lancet
, vol.380
, pp. 1819-1828
-
-
Cohen, J.A.1
Coles, A.J.2
Arnold, D.L.3
Confavreux, C.4
Fox, E.J.5
Hartung, H.P.6
Havrdova, E.7
Selmaj, K.W.8
Weiner, H.L.9
Fisher, E.10
-
27
-
-
84869507357
-
Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: A randomised controlled phase 3 trial
-
Coles, A.J.; Twyman, C.L.; Arnold, D.L.; Cohen, J.A.; Confavreux, C.; Fox, E.J.; Hartung, H.P.; Havrdova, E.; Selmaj, K.W.; Weiner, H.L., et al. Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: A randomised controlled phase 3 trial. Lancet 2012, 380, 1829–1839.
-
(2012)
Lancet
, vol.380
, pp. 1829-1839
-
-
Coles, A.J.1
Twyman, C.L.2
Arnold, D.L.3
Cohen, J.A.4
Confavreux, C.5
Fox, E.J.6
Hartung, H.P.7
Havrdova, E.8
Selmaj, K.W.9
Weiner, H.L.10
-
28
-
-
84922924306
-
Alemtuzumab: A new therapy for active relapsing-remitting multiple sclerosis
-
Hartung, H.P.; Aktas, O.; Boyko, A.N. Alemtuzumab: A new therapy for active relapsing-remitting multiple sclerosis. Mult. Scler. 2015, 21, 22–34.
-
(2015)
Mult. Scler
, vol.21
, pp. 22-34
-
-
Hartung, H.P.1
Aktas, O.2
Boyko, A.N.3
-
29
-
-
84860780657
-
Alemtuzumab more effective than interferon β-1a at 5-year follow-up of CAMMS223 clinical trial
-
Coles, A.J.; Fox, E.; Vladic, A.; Gazda, S.K.; Brinar, V.; Selmaj, K.W.; Skoromets, A.; Stolyarov, I.; Bass, A.; Sullivan, H., et al. Alemtuzumab more effective than interferon β-1a at 5-year follow-up of CAMMS223 clinical trial. Neurology 2012, 78, 1069–1078.
-
(2012)
Neurology
, vol.78
, pp. 1069-1078
-
-
Coles, A.J.1
Fox, E.2
Vladic, A.3
Gazda, S.K.4
Brinar, V.5
Selmaj, K.W.6
Skoromets, A.7
Stolyarov, I.8
Bass, A.9
Sullivan, H.10
-
30
-
-
84937476724
-
Durable effect of alemtuzumab on clinical outcomes in patients with relapsing-remitting multiple sclerosis who relapsed on prior therapy: 4-Year follow-up of CARE-MS II
-
Philadelphia, PA, USA, 26 April–3 May
-
Havrdova, E.; Giovannoni, G.; Arnold, D.L.; Coles, A.J.; Fox, E.J.; Hartung, H.; Selmaj, K.W.; Margolin, D.H.; Palmer, J.; Panzara, M., et al. Durable effect of alemtuzumab on clinical outcomes in patients with relapsing-remitting multiple sclerosis who relapsed on prior therapy: 4-Year follow-up of CARE-MS II. In Proceedings of the AAN Meeting, Philadelphia, PA, USA, 26 April–3 May 2014.
-
(2014)
Proceedings of the AAN Meeting
-
-
Havrdova, E.1
Giovannoni, G.2
Arnold, D.L.3
Coles, A.J.4
Fox, E.J.5
Hartung, H.6
Selmaj, K.W.7
Margolin, D.H.8
Palmer, J.9
Panzara, M.10
-
31
-
-
84937476725
-
Durable effect of alemtuzumab on clinical outcomes in treatment-naive relapsing-remitting multiple sclerosis patients: 4-Year follow-up of CARE-MS I
-
Philadelphia, PA, USA, 26 April–3 May
-
Compston, D.A.S.; Giovannoni, G.; Arnold, D.L.; Fox, E.J.; Hartung, H.; Havrdova, E.; Selmaj, K.W; Margolin, D.H.; Palmer, J.; Panzara, M., et al. Durable effect of alemtuzumab on clinical outcomes in treatment-naive relapsing-remitting multiple sclerosis patients: 4-Year follow-up of CARE-MS I. In Proceedings of the AAN Meeting, Philadelphia, PA, USA, 26 April–3 May 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Compston, D.1
Giovannoni, G.2
Arnold, D.L.3
Fox, E.J.4
Hartung, H.5
Havrdova, E.6
Selmaj, K.W.7
Margolin, D.H.8
Palmer, J.9
Panzara, M.10
-
32
-
-
84937476726
-
Durable effect of alemtuzumab on disability improvement in patients with relapsing-remitting multiple sclerosis who relapsed on a prior therapy
-
Washington, DC, USA, 18–25 April
-
LaGanke, C.; Hughes, B.; Berkovich, R.; Cohen, J.A.; Giovannoni G.; Kasten, L.; Margolin, D.H.; Havrdova, E. Durable effect of alemtuzumab on disability improvement in patients with relapsing-remitting multiple sclerosis who relapsed on a prior therapy. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Laganke, C.1
Hughes, B.2
Berkovich, R.3
Cohen, J.A.4
Giovannoni, G.5
Kasten, L.6
Margolin, D.H.7
Havrdova, E.8
-
33
-
-
84937476727
-
Alemtuzumab slows brain volume loss over 4 years despite most relapsing-remitting multiple sclerosis patients not receiving treatment for 3 years
-
Washington, DC, USA, 18–25 April
-
Coles, A.J.; Arnold, D.L.; Cohen, J.A.; Fox, E.J.; Hartung, H.; Havrdova, E.; Selmaj, K.W.; Margolin, D.H.; Kasten, L.; Panzara, M., et al. Alemtuzumab slows brain volume loss over 4 years despite most relapsing-remitting multiple sclerosis patients not receiving treatment for 3 years. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Coles, A.J.1
Arnold, D.L.2
Cohen, J.A.3
Fox, E.J.4
Hartung, H.5
Havrdova, E.6
Selmaj, K.W.7
Margolin, D.H.8
Kasten, L.9
Panzara, M.10
-
34
-
-
84937476728
-
Durable effect of alemtuzumab on MRI outcomes in patients with relapsing-remitting multiple sclerosis who relapsed on prior therapy: 4-Year follow-up of CARE-MS II
-
Washington, DC, USA, 18–25 April
-
Traboulsee, A.; Coles, A.J.; Cohen, J.A.; Compston, D.A.S.; Fox, E.J.; Hartung, H.; Havrdova, E.; Selmaj, K.W.; Margolin, D.H.; Zhao, Y., et al. Durable effect of alemtuzumab on MRI outcomes in patients with relapsing-remitting multiple sclerosis who relapsed on prior therapy: 4-Year follow-up of CARE-MS II. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Traboulsee, A.1
Coles, A.J.2
Cohen, J.A.3
Compston, D.4
Fox, E.J.5
Hartung, H.6
Havrdova, E.7
Selmaj, K.W.8
Margolin, D.H.9
Zhao, Y.10
-
35
-
-
84937476729
-
Durable effect of alemtuzumab on MRI activity in treatment-naive active relapsing-remitting multiple sclerosis patients: 4-Year follow-up of CARE-MS I
-
Washington, DC, USA, 18–25 April
-
Arnold, D.L.; Traboulsee, A.; Coles, A.J.; Cohen, J.A.; Fox, E.J.; Hartung, H.; Havrdova, E.; Selmaj, K.W.; Margolin, D.H.; Zhao, Y., et al. Durable effect of alemtuzumab on MRI activity in treatment-naive active relapsing-remitting multiple sclerosis patients: 4-Year follow-up of CARE-MS I. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Arnold, D.L.1
Traboulsee, A.2
Coles, A.J.3
Cohen, J.A.4
Fox, E.J.5
Hartung, H.6
Havrdova, E.7
Selmaj, K.W.8
Margolin, D.H.9
Zhao, Y.10
-
36
-
-
84937476730
-
Improvement in clinical outcomes in treatment-naive relapsing-remitting multiple sclerosis patients who switched from subcutaneous interferon β-1a to alemtuzumab
-
Washington, DC, USA, 18–25 April
-
Hartung, H.; Giovannoni, G.; Arnold, D.L.; Coles, A.J.; Fox, E.J.; Havrdova, E.; Selmaj, K.W.; Margolin, D.H.; Compston, D.A.S. Improvement in clinical outcomes in treatment-naive relapsing-remitting multiple sclerosis patients who switched from subcutaneous interferon β-1a to alemtuzumab. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Hartung, H.1
Giovannoni, G.2
Arnold, D.L.3
Coles, A.J.4
Fox, E.J.5
Havrdova, E.6
Selmaj, K.W.7
Margolin, D.H.8
Compston, D.9
-
37
-
-
84937476731
-
Improvement in clinical outcomes following switch from subcutaneous interferon β-1a to alemtuzumab: CARE-MS II extension study
-
Washington, DC, USA, 18–25 April
-
Fox, E.J.; Giovannoni, G.; Arnold, D.L.; Coles, A.J.; Hartung, H.; Havrdova, E.; Selmaj, K.W.; Margolin, D.H.; Compston, D.A.S. Improvement in clinical outcomes following switch from subcutaneous interferon β-1a to alemtuzumab: CARE-MS II extension study. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Fox, E.J.1
Giovannoni, G.2
Arnold, D.L.3
Coles, A.J.4
Hartung, H.5
Havrdova, E.6
Selmaj, K.W.7
Margolin, D.H.8
Compston, D.9
-
38
-
-
84937476732
-
Switching to alemtuzumab from subcutaneous interferon β-1a after CARE-MS I further improved MRI outcomes in patients with relapsing-remitting multiple sclerosis
-
Washington, DC, USA, 18–25 April
-
Barkhof, F.; Pelletier, D.; Coles, A.J.; Cohen, J.A.; Compston, D.A.S.; Fox, E.J.; Hartung, H.; Havrdova, E.; Margolin, D.H.; Kasten, L., et al. Switching to alemtuzumab from subcutaneous interferon β-1a after CARE-MS I further improved MRI outcomes in patients with relapsing-remitting multiple sclerosis. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Barkhof, F.1
Pelletier, D.2
Coles, A.J.3
Cohen, J.A.4
Compston, D.5
Fox, E.J.6
Hartung, H.7
Havrdova, E.8
Margolin, D.H.9
Kasten, L.10
-
39
-
-
84937476733
-
Switching to alemtuzumab from subcutaneous interferon β-1a after CARE-MS II further improved MRI outcomes in patients with relapsing-remitting multiple sclerosis
-
Washington, DC, USA, 18–25 April
-
Pelletier, D.; Barkhof, F.; Coles, A.J.; Cohen, J.A.; Compston, D.A.S.; Fox, E.J.; Hartung, H.; Havrdova, E.; Margolin, D.H.; Kasten, L., et al. Switching to alemtuzumab from subcutaneous interferon β-1a after CARE-MS II further improved MRI outcomes in patients with relapsing-remitting multiple sclerosis. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Pelletier, D.1
Barkhof, F.2
Coles, A.J.3
Cohen, J.A.4
Compston, D.5
Fox, E.J.6
Hartung, H.7
Havrdova, E.8
Margolin, D.H.9
Kasten, L.10
-
40
-
-
84937476734
-
Slowing of brain volume loss in patients with relapsing-remitting multiple sclerosis after switching from subcutaneous interferon β-1a to alemtuzumab
-
Washington, DC, USA, 18–25 April
-
Cohen, J.A.; Arnold, D.L.; Coles, A.J.; Fox, E.J.; Hartung, H.; Havrdova, E.; Selmaj, K.W.; Margolin, D.H.; Kasten, L.; Compston, D.A.S. Slowing of brain volume loss in patients with relapsing-remitting multiple sclerosis after switching from subcutaneous interferon β-1a to alemtuzumab. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Cohen, J.A.1
Arnold, D.L.2
Coles, A.J.3
Fox, E.J.4
Hartung, H.5
Havrdova, E.6
Selmaj, K.W.7
Margolin, D.H.8
Kasten, L.9
Compston, D.10
-
41
-
-
34248531422
-
Cytokine-release syndrome: Overview and nursing implications
-
Breslin, S. Cytokine-release syndrome: Overview and nursing implications. Clin. J. Oncol. Nurs. 2007, 11, 37–42.
-
(2007)
Clin. J. Oncol. Nurs
, vol.11
, pp. 37-42
-
-
Breslin, S.1
-
42
-
-
78650578346
-
Acute infusion reactions induced by monoclonal antibody therapy
-
Maggi, E.; Vultaggio, A.; Matucci, A. Acute infusion reactions induced by monoclonal antibody therapy. Expert Rev. Clin. Immunol. 2011, 7, 55–63.
-
(2011)
Expert Rev. Clin. Immunol
, vol.7
, pp. 55-63
-
-
Maggi, E.1
Vultaggio, A.2
Matucci, A.3
-
43
-
-
84921019450
-
Alemtuzumab infusion-associated reactions and management in multiple sclerosis
-
Mayer, L.; Casady, L.; Clayton, G.; Oyuela, P.; Margolin, D. Alemtuzumab infusion-associated reactions and management in multiple sclerosis. J. Infus. Nurs. Manag. (Harrow) 2014, 37, 250–258.
-
(2014)
J. Infus. Nurs. Manag. (Harrow)
, vol.37
, pp. 250-258
-
-
Mayer, L.1
Casady, L.2
Clayton, G.3
Oyuela, P.4
Margolin, D.5
-
44
-
-
84937476735
-
Administration of alemtuzumab on nonconsecutive days does not impact infusion-associated reactions, efficacy, or lymphocyte depletion
-
Washington, DC, USA, 18–25 April
-
Wray, S.; Boyko, A.N.; Braley, T.J.; Khan, O.; Margolin, D.H.; Coles, A.J. Administration of alemtuzumab on nonconsecutive days does not impact infusion-associated reactions, efficacy, or lymphocyte depletion. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Wray, S.1
Boyko, A.N.2
Braley, T.J.3
Khan, O.4
Margolin, D.H.5
Coles, A.J.6
-
45
-
-
84937476736
-
Evaluation of comprehensive alemtuzumab infusion guidance in patients with relapsing-remitting multiple sclerosis: Emerald study design
-
Washington, DC, USA, 18–25 April
-
Vermersch, P.; Vanopdenbosch, L.J.; González, R.A.; Fernandez, O.; Baldinetti, F.; Krolczyk, S.; Martell, L.; Moreau, T. Evaluation of comprehensive alemtuzumab infusion guidance in patients with relapsing-remitting multiple sclerosis: Emerald study design. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Vermersch, P.1
Vanopdenbosch, L.J.2
González, R.A.3
Fernandez, O.4
Baldinetti, F.5
Krolczyk, S.6
Martell, L.7
Moreau, T.8
-
46
-
-
84993707836
-
Herpes infection risk reduced with acyclovir prophylaxis after alemtuzumab
-
Orlando, FL, USA, 27–30 May
-
Wray, S.; Arnold, D.L.; Cohen, J.; Coles, A.; Fox, E.; Hartung, H. Herpes infection risk reduced with acyclovir prophylaxis after alemtuzumab. In Proceedings of the Annual Meeting of the Consortium of Multiple Sclerosis Centers (CMSC), Orlando, FL, USA, 27–30 May 2013.
-
(2013)
Proceedings of the Annual Meeting of the Consortium of Multiple Sclerosis Centers (CMSC)
-
-
Wray, S.1
Arnold, D.L.2
Cohen, J.3
Coles, A.4
Fox, E.5
Hartung, H.6
-
47
-
-
84937476738
-
Incidence of infection decreases over time in alemtuzumab-treated patients with relapsing-remitting multiple sclerosis: 4-year follow-up of the CARE-MS studies
-
Washington, DC, USA, 18–25 April
-
Henson, L.J.; Arnold, D.L.; Cohen, J.A.; Coles, A.J.; Fox, E.J.; Hartung, H.; Havrdova, E.; Selmaj, K.W.; Margolin, D.H.; Compston, D.A.S. Incidence of infection decreases over time in alemtuzumab-treated patients with relapsing-remitting multiple sclerosis: 4-year follow-up of the CARE-MS studies. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Henson, L.J.1
Arnold, D.L.2
Cohen, J.A.3
Coles, A.J.4
Fox, E.J.5
Hartung, H.6
Havrdova, E.7
Selmaj, K.W.8
Margolin, D.H.9
Compston, D.10
-
48
-
-
0036721489
-
Peripheral blood but not tissue dendritic cells express CD52 and are depleted by treatment with alemtuzumab
-
Buggins, A.G.; Mufti, G.J.; Salisbury, J.; Codd, J.; Westwood, N.; Arno, M.; Fishlock, K.; Pagliuca, A.; Devereux, S. Peripheral blood but not tissue dendritic cells express CD52 and are depleted by treatment with alemtuzumab. Blood 2002, 100, 1715–1720.
-
(2002)
Blood
, vol.100
, pp. 1715-1720
-
-
Buggins, A.G.1
Mufti, G.J.2
Salisbury, J.3
Codd, J.4
Westwood, N.5
Arno, M.6
Fishlock, K.7
Pagliuca, A.8
Devereux, S.9
-
49
-
-
84884643373
-
Immune competence after alemtuzumab treatment of multiple sclerosis
-
McCarthy, C.L.; Tuohy, O.; Compston, D.A.; Kumararatne, D.S.; Coles, A.J.; Jones, J.L. Immune competence after alemtuzumab treatment of multiple sclerosis. Neurology 2013, 81, 872–876.
-
(2013)
Neurology
, vol.81
, pp. 872-876
-
-
McCarthy, C.L.1
Tuohy, O.2
Compston, D.A.3
Kumararatne, D.S.4
Coles, A.J.5
Jones, J.L.6
-
50
-
-
84856072398
-
Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated ctcl patients
-
Clark, R.A.; Watanabe, R.; Teague, J.E.; Schlapbach, C.; Tawa, M.C.; Adams, N.; Dorosario, A.A.; Chaney, K.S.; Cutler, C.S.; Leboeuf, N.R., et al. Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated ctcl patients. Sci. Transl. Med. 2012, 4, 117-117.
-
(2012)
Sci. Transl. Med
, vol.4
-
-
Clark, R.A.1
Watanabe, R.2
Teague, J.E.3
Schlapbach, C.4
Tawa, M.C.5
Adams, N.6
Dorosario, A.A.7
Chaney, K.S.8
Cutler, C.S.9
Leboeuf, N.R.10
-
51
-
-
84993707958
-
Analysis of data from rrms alemtuzumab-treated patients in the clinical program to evaluate incidence rates of malignancy
-
Boston, MA, USA, 10–13 September
-
Miller, T.; Habek, M.; Coles, A.; Selmaj, K.; Margolin, D.; Palmer, J. Analysis of data from rrms alemtuzumab-treated patients in the clinical program to evaluate incidence rates of malignancy. In Proceedings of the Join ACTRIMS-ECTRIMS Meeting, Boston, MA, USA, 10–13 September 2014.
-
(2014)
Proceedings of the Join ACTRIMS-ECTRIMS Meeting
-
-
Miller, T.1
Habek, M.2
Coles, A.3
Selmaj, K.4
Margolin, D.5
Palmer, J.6
-
52
-
-
84937476740
-
-
accessed on 4 May
-
Alemtuzumab prescribing information. Available online: http://www.Accessdata.Fda.Gov/drugsatfda_docs/label/2014/103948s5139lbl.Pdf (accessed on 4 May 2015).
-
(2015)
-
-
-
53
-
-
84939966439
-
Pregnancy outcomes in the alemtuzumab multiple sclerosis clinical development program
-
Boston, MA, USA, 10–13 September
-
McCombe, P.; Achiron, A.; Giovannoni, G.; Brinar, V.; Margolin, D.; Palmer, J. Pregnancy outcomes in the alemtuzumab multiple sclerosis clinical development program. In Proceedings of the Join ACTRIMS-ECTRIMS Meeting, Boston, MA, USA, 10–13 September 2014.
-
(2014)
Proceedings of the Join ACTRIMS-ECTRIMS Meeting
-
-
McCombe, P.1
Achiron, A.2
Giovannoni, G.3
Brinar, V.4
Margolin, D.5
Palmer, J.6
-
54
-
-
84937476742
-
Alemtuzumab treatment has no adverse impact on sperm quality, quantity, or motility: A care-MS substudy
-
Vienna, Austria, 21–26 September
-
Margolin, D.; Rizzo, M.; Smith, G.; Arnold, D.; Coles, A.; Hartung, H. Alemtuzumab treatment has no adverse impact on sperm quality, quantity, or motility: A care-MS substudy. In Proceedings of the 21st World Congress of Neurology, Vienna, Austria, 21–26 September 2013.
-
(2013)
Proceedings of the 21st World Congress of Neurology
-
-
Margolin, D.1
Rizzo, M.2
Smith, G.3
Arnold, D.4
Coles, A.5
Hartung, H.6
-
55
-
-
84892156601
-
Alemtuzumab-related thyroid dysfunction in a phase 2 trial of patients with relapsing-remitting multiple sclerosis
-
Daniels, G.H.; Vladic, A.; Brinar, V.; Zavalishin, I.; Valente, W.; Oyuela, P.; Palmer, J.; Margolin, D.H.; Hollenstein, J. Alemtuzumab-related thyroid dysfunction in a phase 2 trial of patients with relapsing-remitting multiple sclerosis. J. Clin. Endocrinol. Metab. 2014, 99, 80–89.
-
(2014)
J. Clin. Endocrinol. Metab
, vol.99
, pp. 80-89
-
-
Daniels, G.H.1
Vladic, A.2
Brinar, V.3
Zavalishin, I.4
Valente, W.5
Oyuela, P.6
Palmer, J.7
Margolin, D.H.8
Hollenstein, J.9
-
56
-
-
84890285333
-
Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation
-
Jones, J.L.; Thompson, S.A.; Loh, P.; Davies, J.L.; Tuohy, O.C.; Curry, A.J.; Azzopardi, L.; Hill-Cawthorne, G.; Fahey, M.T.; Compston, A., et al. Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation. Proc. Natl. Acad. Sci. USA 2013, 110, 20200–20205.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 20200-20205
-
-
Jones, J.L.1
Thompson, S.A.2
Loh, P.3
Davies, J.L.4
Tuohy, O.C.5
Curry, A.J.6
Azzopardi, L.7
Hill-Cawthorne, G.8
Fahey, M.T.9
Compston, A.10
-
57
-
-
84937476743
-
The efficacy of alemtuzumab is maintained in patients who develop thyroid adverse events
-
on behalf of the CARE-MS Investigators, Washinton, DC, USA, 18–25 April
-
Hunter, S.F.; Arnold, D.L.; Coles, A.J.; Cohen, J.A.; Fox, E.J.; Hartung, H.; Havrdova, E.; Margolin, D.H.; Compston, D.A.S.; on behalf of the CARE-MS Investigators. The efficacy of alemtuzumab is maintained in patients who develop thyroid adverse events. In Proceedings of the AAN Meeting, Washinton, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Hunter, S.F.1
Arnold, D.L.2
Coles, A.J.3
Cohen, J.A.4
Fox, E.J.5
Hartung, H.6
Havrdova, E.7
Margolin, D.H.8
Compston, D.9
-
58
-
-
33746189876
-
Autoimmunity during lymphopenia: A two-hit model
-
Krupica, T., Jr.; Fry, T.J.; Mackall, C.L. Autoimmunity during lymphopenia: A two-hit model. Clin. Immunol. 2006, 120, 121–128.
-
(2006)
Clin. Immunol
, vol.120
, pp. 121-128
-
-
Krupica, T.1
Fry, T.J.2
Mackall, C.L.3
-
60
-
-
0027517545
-
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
-
Powrie, F.; Leach, M.W.; Mauze, S.; Caddle, L.B.; Coffman, R.L. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int. Immunol. 1993, 5, 1461–1471.
-
(1993)
Int. Immunol
, vol.5
, pp. 1461-1471
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
Caddle, L.B.4
Coffman, R.L.5
-
61
-
-
47549112840
-
IL-21 and TGF-β are required for differentiation of human T(H)17 cells
-
Yang, L.; Anderson, D.E.; Baecher-Allan, C.; Hastings, W.D.; Bettelli, E.; Oukka, M.; Kuchroo, V.K.; Hafler, D.A. IL-21 and TGF-β are required for differentiation of human T(h)17 cells. Nature 2008, 454, 350–352.
-
(2008)
Nature
, vol.454
, pp. 350-352
-
-
Yang, L.1
Anderson, D.E.2
Baecher-Allan, C.3
Hastings, W.D.4
Bettelli, E.5
Oukka, M.6
Kuchroo, V.K.7
Hafler, D.A.8
-
62
-
-
29144519767
-
IL-21 induces differentiation of human naive and memory b cells into antibody-secreting plasma cells
-
Ettinger, R.; Sims, G.P.; Fairhurst, A.M.; Robbins, R.; da Silva, Y.S.; Spolski, R.; Leonard, W.J.; Lipsky, P.E. IL-21 induces differentiation of human naive and memory b cells into antibody-secreting plasma cells. J. Immunol. 2005, 175, 7867–7879.
-
(2005)
J. Immunol
, vol.175
, pp. 7867-7879
-
-
Ettinger, R.1
Sims, G.P.2
Fairhurst, A.M.3
Robbins, R.4
Da Silva, Y.S.5
Spolski, R.6
Leonard, W.J.7
Lipsky, P.E.8
-
63
-
-
45949090105
-
Release from regulatory T Cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21
-
Clough, L.E.; Wang, C.J.; Schmidt, E.M.; Booth, G.; Hou, T.Z.; Ryan, G.A.; Walker, L.S. Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21. J. Immunol. 2008, 180, 5393–5401.
-
(2008)
J. Immunol
, vol.180
, pp. 5393-5401
-
-
Clough, L.E.1
Wang, C.J.2
Schmidt, E.M.3
Booth, G.4
Hou, T.Z.5
Ryan, G.A.6
Walker, L.S.7
-
64
-
-
33846196712
-
IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes
-
Peluso, I.; Fantini, M.C.; Fina, D.; Caruso, R.; Boirivant, M.; MacDonald, T.T.; Pallone, F.; Monteleone, G. IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes. J. Immunol. 2007, 178, 732–739.
-
(2007)
J. Immunol
, vol.178
, pp. 732-739
-
-
Peluso, I.1
Fantini, M.C.2
Fina, D.3
Caruso, R.4
Boirivant, M.5
Macdonald, T.T.6
Pallone, F.7
Monteleone, G.8
-
65
-
-
3843124199
-
Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function
-
Chu, Y.W.; Memon, S.A.; Sharrow, S.O.; Hakim, F.T.; Eckhaus, M.; Lucas, P.J.; Gress, R.E. Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function. Blood 2004, 104, 1110–1119.
-
(2004)
Blood
, vol.104
, pp. 1110-1119
-
-
Chu, Y.W.1
Memon, S.A.2
Sharrow, S.O.3
Hakim, F.T.4
Eckhaus, M.5
Lucas, P.J.6
Gress, R.E.7
-
66
-
-
84937476744
-
Predicting autoimmunity following treatment of multiple sclerosis with alemtuzumab
-
Amsterdam, The Netherlands, 19–22 October
-
Jones, J.L.; Compston, D.A.S.; Coles, A.J. Predicting autoimmunity following treatment of multiple sclerosis with alemtuzumab. In Proceedings of the ECTRIMS Meeting, Amsterdam, The Netherlands, 19–22 October 2011.
-
(2011)
Proceedings of the ECTRIMS Meeting
-
-
Jones, J.L.1
Compston, D.2
Coles, A.J.3
-
67
-
-
0034023587
-
Autoimmune disease in first-degree relatives of patients with multiple sclerosis. A UK survey
-
Broadley, S.A.; Deans, J.; Sawcer, S.J.; Clayton, D.; Compston, D.A. Autoimmune disease in first-degree relatives of patients with multiple sclerosis. A UK survey. Brain 2000, 123 Pt 6, 1102–1111.
-
(2000)
Brain
, vol.123
, pp. 1102-1111
-
-
Broadley, S.A.1
Deans, J.2
Sawcer, S.J.3
Clayton, D.4
Compston, D.A.5
-
68
-
-
49449108196
-
Anti-glomerular basement membrane disease after alemtuzumab
-
Clatworthy, M.R.; Wallin, E.F.; Jayne, D.R. Anti-glomerular basement membrane disease after alemtuzumab. N. Engl. J. Med. 2008, 359, 768–769.
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 768-769
-
-
Clatworthy, M.R.1
Wallin, E.F.2
Jayne, D.R.3
-
69
-
-
84860488313
-
HLA-DRB1*15:01 and multiple sclerosis: A female association?
-
Irizar, H.; Munoz-Culla, M.; Zuriarrain, O.; Goyenechea, E.; Castillo-Trivino, T.; Prada, A.; Saenz-Cuesta, M.; de Juan, D.; Lopez de Munain, A.; Olascoaga, J., et al. HLA-DRB1*15:01 and multiple sclerosis: A female association? Mult. Scler. 2012, 18, 569–577.
-
(2012)
Mult. Scler
, vol.18
, pp. 569-577
-
-
Irizar, H.1
Munoz-Culla, M.2
Zuriarrain, O.3
Goyenechea, E.4
Castillo-Trivino, T.5
Prada, A.6
Saenz-Cuesta, M.7
de Juan, D.8
de Lopez Munain, A.9
Olascoaga, J.10
-
70
-
-
80053207130
-
Autoimmune disease after alemtuzumab treatment for multiple sclerosis in a multicenter cohort
-
Cossburn, M.; Pace, A.A.; Jones, J.; Ali, R.; Ingram, G.; Baker, K.; Hirst, C.; Zajicek, J.; Scolding, N.; Boggild, M., et al. Autoimmune disease after alemtuzumab treatment for multiple sclerosis in a multicenter cohort. Neurology 2011, 77, 573–579.
-
(2011)
Neurology
, vol.77
, pp. 573-579
-
-
Cossburn, M.1
Pace, A.A.2
Jones, J.3
Ali, R.4
Ingram, G.5
Baker, K.6
Hirst, C.7
Zajicek, J.8
Scolding, N.9
Boggild, M.10
-
71
-
-
71649083353
-
Clustering and commonalities among autoimmune diseases
-
Mackay, I.R. Clustering and commonalities among autoimmune diseases. J. Autoimmun. 2009, 33, 170–177.
-
(2009)
J. Autoimmun
, vol.33
, pp. 170-177
-
-
Mackay, I.R.1
-
72
-
-
27944439639
-
Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis
-
Cox, A.L.; Thompson, S.A.; Jones, J.L.; Robertson, V.H.; Hale, G.; Waldmann, H.; Compston, D.A.; Coles, A.J. Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur. J. Immunol. 2005, 35, 3332–3342.
-
(2005)
Eur. J. Immunol
, vol.35
, pp. 3332-3342
-
-
Cox, A.L.1
Thompson, S.A.2
Jones, J.L.3
Robertson, V.H.4
Hale, G.5
Waldmann, H.6
Compston, D.A.7
Coles, A.J.8
-
73
-
-
40449101381
-
CD4+CD25+FoxP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H
-
Bloom, D.D.; Chang, Z.; Fechner, J.H.; Dar, W.; Polster, S.P.; Pascual, J.; Turka, L.A.; Knechtle, S.J. CD4+CD25+FoxP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H. Am. J. Transplant. 2008, 8, 793–802.
-
(2008)
Am. J. Transplant
, vol.8
, pp. 793-802
-
-
Bloom, D.D.1
Chang, Z.2
Fechner, J.H.3
Dar, W.4
Polster, S.P.5
Pascual, J.6
Turka, L.A.7
Knechtle, S.J.8
-
74
-
-
77957044257
-
Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity
-
Jones, J.L.; Anderson, J.M.; Phuah, C.L.; Fox, E.J.; Selmaj, K.; Margolin, D.; Lake, S.L.; Palmer, J.; Thompson, S.J.; Wilkins, A., et al. Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity. Brain 2010, 133, 2232–2247.
-
(2010)
Brain
, vol.133
, pp. 2232-2247
-
-
Jones, J.L.1
Anderson, J.M.2
Phuah, C.L.3
Fox, E.J.4
Selmaj, K.5
Margolin, D.6
Lake, S.L.7
Palmer, J.8
Thompson, S.J.9
Wilkins, A.10
-
75
-
-
84890400796
-
Differential reconstitution of T cell subsets following immunodepleting treatment with alemtuzumab (Anti-CD52 monoclonal antibody) in patients with relapsing-remitting multiple sclerosis
-
Zhang, X.; Tao, Y.; Chopra, M.; Ahn, M.; Marcus, K.L.; Choudhary, N.; Zhu, H.; Markovic-Plese, S. Differential reconstitution of T cell subsets following immunodepleting treatment with alemtuzumab (anti-CD52 monoclonal antibody) in patients with relapsing-remitting multiple sclerosis. J. Immunol. 2013, 191, 5867–5874.
-
(2013)
J. Immunol
, vol.191
, pp. 5867-5874
-
-
Zhang, X.1
Tao, Y.2
Chopra, M.3
Ahn, M.4
Marcus, K.L.5
Choudhary, N.6
Zhu, H.7
Markovic-Plese, S.8
-
76
-
-
47049100425
-
Activation of myelin reactive t cells in multiple sclerosis: A possible role for t cell degeneracy?
-
Stinissen, P.; Hellings, N. Activation of myelin reactive t cells in multiple sclerosis: A possible role for t cell degeneracy? Eur. J. Immunol. 2008, 38, 1190–1193.
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 1190-1193
-
-
Stinissen, P.1
Hellings, N.2
-
77
-
-
84937476745
-
Activity of an anti-murine CD52 antibody in experimental autoimmune encephalomyelitis
-
New Orleans, LA, USA, 22–27 April
-
Turner, M.; Chretien, N.; Havari, E.; LaMorte, M.; Roberts B.; Kaplan J.; Siders, W. Activity of an anti-murine CD52 antibody in experimental autoimmune encephalomyelitis. In Proceedings of the AAN Meeting, New Orleans, LA, USA, 22–27 April 2012.
-
(2012)
Proceedings of the AAN Meeting
-
-
Turner, M.1
Chretien, N.2
Havari, E.3
Lamorte, M.4
Roberts, B.5
Kaplan, J.6
Siders, W.7
-
78
-
-
84937476746
-
Anti-murine CD52 antibody treatment does not adversely affect the migratory ability of immune cells
-
Philadelphia, PA, USA, 26 April–3 May
-
Havari, E.; Turner, M.; Dodge, J.; Treleaven, C.; Shihabuddin, L.; Roberts, B.; Kaplan, J.; Siders, W. Anti-murine CD52 antibody treatment does not adversely affect the migratory ability of immune cells. In Proceedings of the AAN Meeting, Philadelphia, PA, USA, 26 April–3 May 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Havari, E.1
Turner, M.2
Dodge, J.3
Treleaven, C.4
Shihabuddin, L.5
Roberts, B.6
Kaplan, J.7
Siders, W.8
-
79
-
-
84922588873
-
Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic colitis
-
Wang, H.; Dong, J.; Shi, P.; Liu, J.; Zuo, L.; Li, Y.; Gong, J.; Gu, L.; Zhao, J.; Zhang, L., et al. Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic colitis. Immunology 2015, 144, 254–262.
-
(2015)
Immunology
, vol.144
, pp. 254-262
-
-
Wang, H.1
Dong, J.2
Shi, P.3
Liu, J.4
Zuo, L.5
Li, Y.6
Gong, J.7
Gu, L.8
Zhao, J.9
Zhang, L.10
-
80
-
-
84880849711
-
Immune status following alemtuzumab treatment in human CD52 transgenic mice
-
Turner, M.J.; Lamorte, M.J.; Chretien, N.; Havari, E.; Roberts, B.L.; Kaplan, J.M.; Siders, W.M. Immune status following alemtuzumab treatment in human CD52 transgenic mice. J. Neuroimmunol. 2013, 261, 29–36.
-
(2013)
J. Neuroimmunol
, vol.261
, pp. 29-36
-
-
Turner, M.J.1
Lamorte, M.J.2
Chretien, N.3
Havari, E.4
Roberts, B.L.5
Kaplan, J.M.6
Siders, W.M.7
-
81
-
-
84937398076
-
Reduction of inflammation and preservation of neurological function by anti-CD52 therapy in murine experimental autoimmune encephalomyelitis
-
Turner, M.; Pang, P.T.; Chretien, N.; Havari, E.; LaMorte, M.J.; Oliver, J.; Pande, N.; Masterjohn, E.; Carter, K.; Reczek, D., et al. Reduction of inflammation and preservation of neurological function by anti-CD52 therapy in murine experimental autoimmune encephalomyelitis. J. Neuroimmunol. 2015, 285, 4–12.
-
(2015)
J. Neuroimmunol
, vol.285
, pp. 4-12
-
-
Turner, M.1
Pang, P.T.2
Chretien, N.3
Havari, E.4
Lamorte, M.J.5
Oliver, J.6
Pande, N.7
Masterjohn, E.8
Carter, K.9
Reczek, D.10
-
82
-
-
11144221749
-
The new paradigm of T-cell homeostatic proliferation-induced autoimmunity
-
Baccala, R.; Theofilopoulos, A.N. The new paradigm of T-cell homeostatic proliferation-induced autoimmunity. Trends Immunol. 2005, 26, 5–8.
-
(2005)
Trends Immunol
, vol.26
, pp. 5-8
-
-
Baccala, R.1
Theofilopoulos, A.N.2
-
83
-
-
0037460071
-
Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells
-
Kassiotis, G.; Zamoyska, R.; Stockinger, B. Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells. J. Exp. Med. 2003, 197, 1007–1016.
-
(2003)
J. Exp. Med
, vol.197
, pp. 1007-1016
-
-
Kassiotis, G.1
Zamoyska, R.2
Stockinger, B.3
-
84
-
-
58449122094
-
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells
-
Guimond, M.; Veenstra, R.G.; Grindler, D.J.; Zhang, H.; Cui, Y.; Murphy, R.D.; Kim, S.Y.; Na, R.; Hennighausen, L.; Kurtulus, S., et al. Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. Nat. Immunol. 2009, 10, 149–157.
-
(2009)
Nat. Immunol
, vol.10
, pp. 149-157
-
-
Guimond, M.1
Veenstra, R.G.2
Grindler, D.J.3
Zhang, H.4
Cui, Y.5
Murphy, R.D.6
Kim, S.Y.7
Na, R.8
Hennighausen, L.9
Kurtulus, S.10
-
85
-
-
84881096188
-
Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system
-
Sinclair, C.; Bains, I.; Yates, A.J.; Seddon, B. Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system. Proc. Natl. Acad. Sci. USA 2013, 110, E2905–2914.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. E2905-E2914
-
-
Sinclair, C.1
Bains, I.2
Yates, A.J.3
Seddon, B.4
-
86
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 Years of merits and culprits in experimental autoimmune encephalomyelitis research
-
Gold, R.; Linington, C.; Lassmann, H. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 Years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 2006, 129, 1953–1971.
-
(2006)
Brain
, vol.129
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
87
-
-
84911381441
-
Isolation of primary murine brain microvascular endothelial cells
-
Ruck, T.; Bittner, S.; Epping, L.; Herrmann, A.M.; Meuth, S.G. Isolation of primary murine brain microvascular endothelial cells. J. Vis. Exp. 2014, 93, e52204.
-
(2014)
J. Vis. Exp
, vol.93
-
-
Ruck, T.1
Bittner, S.2
Epping, L.3
Herrmann, A.M.4
Meuth, S.G.5
-
88
-
-
84982234400
-
Secondary progression and innate immunity in nmo: A possible link to alemtuzumab therapy? Neurol. Neuroimmunol
-
Fujihara, K.; Nakashima, I. Secondary progression and innate immunity in nmo: A possible link to alemtuzumab therapy? Neurol. Neuroimmunol. Neuroinflammation 2014, 1, e38.
-
(2014)
Neuroinflammation
, vol.1
-
-
Fujihara, K.1
Nakashima, I.2
-
89
-
-
84948185953
-
Massive CNS monocytic infiltration at autopsy in an alemtuzumab-treated patient with nmo. Neurol. Neuroimmunol
-
Gelfand, J.M.; Cotter, J.; Klingman, J.; Huang, E.J.; Cree, B.A. Massive CNS monocytic infiltration at autopsy in an alemtuzumab-treated patient with nmo. Neurol. Neuroimmunol. Neuroinflammation 2014, 1, e34.
-
(2014)
Neuroinflammation
, vol.1
-
-
Gelfand, J.M.1
Cotter, J.2
Klingman, J.3
Huang, E.J.4
Cree, B.A.5
-
90
-
-
0035693963
-
Delivery of neurotrophic factors to the central nervous system: Pharmacokinetic considerations
-
Thorne, R.G.; Frey, W.H. 2nd. Delivery of neurotrophic factors to the central nervous system: Pharmacokinetic considerations. Clin. Pharmacokinet. 2001, 40, 907–946.
-
(2001)
Clin. Pharmacokinet
, vol.40
, pp. 907-946
-
-
Thorne, R.G.1
Frey, W.H.2
-
91
-
-
84903985522
-
Accelerated lymphocyte recovery after alemtuzumab does not predict multiple sclerosis activity
-
Kousin-Ezewu, O.; Azzopardi, L.; Parker, R.A.; Tuohy, O.; Compston, A.; Coles, A.; Jones, J. Accelerated lymphocyte recovery after alemtuzumab does not predict multiple sclerosis activity. Neurology 2014, 82, 2158–2164.
-
(2014)
Neurology
, vol.82
, pp. 2158-2164
-
-
Kousin-Ezewu, O.1
Azzopardi, L.2
Parker, R.A.3
Tuohy, O.4
Compston, A.5
Coles, A.6
Jones, J.7
-
92
-
-
35648948324
-
Multiple sclerosis: T-cell receptor expression in distinct brain regions
-
Junker, A.; Ivanidze, J.; Malotka, J.; Eiglmeier, I.; Lassmann, H.; Wekerle, H.; Meinl, E.; Hohlfeld, R.; Dornmair, K. Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain 2007, 130, 2789–2799.
-
(2007)
Brain
, vol.130
, pp. 2789-2799
-
-
Junker, A.1
Ivanidze, J.2
Malotka, J.3
Eiglmeier, I.4
Lassmann, H.5
Wekerle, H.6
Meinl, E.7
Hohlfeld, R.8
Dornmair, K.9
-
93
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
Cohen, J.A.; Barkhof, F.; Comi, G.; Hartung, H.P.; Khatri, B.O.; Montalban, X.; Pelletier, J.; Capra, R.; Gallo, P.; Izquierdo, G., et al. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N. Engl. J. Med. 2010, 362, 402–415.
-
(2010)
N. Engl. J. Med
, vol.362
, pp. 402-415
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
Hartung, H.P.4
Khatri, B.O.5
Montalban, X.6
Pelletier, J.7
Capra, R.8
Gallo, P.9
Izquierdo, G.10
-
94
-
-
76149093586
-
A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
-
Kappos, L.; Radue, E.W.; O'Connor, P.; Polman, C.; Hohlfeld, R.; Calabresi, P.; Selmaj, K.; Agoropoulou, C.; Leyk, M.; Zhang-Auberson, L., et al. A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis. N. Engl. J. Med. 2010, 362, 387–401.
-
(2010)
N. Engl. J. Med
, vol.362
, pp. 387-401
-
-
Kappos, L.1
Radue, E.W.2
O'connor, P.3
Polman, C.4
Hohlfeld, R.5
Calabresi, P.6
Selmaj, K.7
Agoropoulou, C.8
Leyk, M.9
Zhang-Auberson, L.10
-
95
-
-
84914173724
-
No evidence of disease activity: Indirect comparisons of oral therapies for the treatment of relapsing-remitting multiple sclerosis
-
Nixon, R.; Bergvall, N.; Tomic, D.; Sfikas, N.; Cutter, G.; Giovannoni, G. No evidence of disease activity: Indirect comparisons of oral therapies for the treatment of relapsing-remitting multiple sclerosis. Adv. Ther. 2014, 31, 1134–1154.
-
(2014)
Adv. Ther
, vol.31
, pp. 1134-1154
-
-
Nixon, R.1
Bergvall, N.2
Tomic, D.3
Sfikas, N.4
Cutter, G.5
Giovannoni, G.6
-
96
-
-
84937476749
-
Fingolimod treatment increases the proportion of patients who are free from disease activity in multiple sclerosis compared to IFNβ-1a: Results from a phase 3, active-controlled study (transforms)
-
New Orleans, LA, USA, 23 April
-
Khatri, B.; Barkhof, F.; Comi, G.; Jin, J.; Francis, G.; Cohen, J. Fingolimod treatment increases the proportion of patients who are free from disease activity in multiple sclerosis compared to IFNβ-1a: Results from a phase 3, active-controlled study (transforms). In Proceedings of the AAN Meeting, New Orleans, LA, USA, 23 April 2012.
-
(2012)
Proceedings of the AAN Meeting
-
-
Khatri, B.1
Barkhof, F.2
Comi, G.3
Jin, J.4
Francis, G.5
Cohen, J.6
-
97
-
-
33644584352
-
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
-
Polman, C.H.; O’Connor, P.W.; Havrdova, E.; Hutchinson, M.; Kappos, L.; Miller, D.H.; Phillips, J.T.; Lublin, F.D.; Giovannoni, G.; Wajgt, A., et al. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N. Engl. J. Med. 2006, 354, 899–910.
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 899-910
-
-
Polman, C.H.1
O’Connor, P.W.2
Havrdova, E.3
Hutchinson, M.4
Kappos, L.5
Miller, D.H.6
Phillips, J.T.7
Lublin, F.D.8
Giovannoni, G.9
Wajgt, A.10
-
98
-
-
60049089535
-
Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: A retrospective analysis of the natalizumab safety and efficacy in relapsing-remitting multiple sclerosis (affirm) study
-
Havrdova, E.; Galetta, S.; Hutchinson, M.; Stefoski, D.; Bates, D.; Polman, C.H.; O'Connor, P.W.; Giovannoni, G.; Phillips, J.T.; Lublin, F.D., et al. Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: A retrospective analysis of the natalizumab safety and efficacy in relapsing-remitting multiple sclerosis (affirm) study. Lancet Neurol. 2009, 8, 254–260.
-
(2009)
Lancet Neurol
, vol.8
, pp. 254-260
-
-
Havrdova, E.1
Galetta, S.2
Hutchinson, M.3
Stefoski, D.4
Bates, D.5
Polman, C.H.6
O'connor, P.W.7
Giovannoni, G.8
Phillips, J.T.9
Lublin, F.D.10
-
99
-
-
84902179860
-
Predicting autoimmunity after alemtuzumab treatment of multiple sclerosis
-
Azzopardi, L.; Thompson, S.A.; Harding, K.E.; Cossburn, M.; Robertson, N.; Compston, A.; Coles, A.J.; Jones, J.L. Predicting autoimmunity after alemtuzumab treatment of multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 2014, 85, 795–798.
-
(2014)
J. Neurol. Neurosurg. Psychiatry
, vol.85
, pp. 795-798
-
-
Azzopardi, L.1
Thompson, S.A.2
Harding, K.E.3
Cossburn, M.4
Robertson, N.5
Compston, A.6
Coles, A.J.7
Jones, J.L.8
-
100
-
-
84873690365
-
Clinical relevance of differential lymphocyte recovery after alemtuzumab therapy for multiple sclerosis
-
Cossburn, M.D.; Harding, K.; Ingram, G.; El-Shanawany, T.; Heaps, A.; Pickersgill, T.P.; Jolles, S.; Robertson, N.P. Clinical relevance of differential lymphocyte recovery after alemtuzumab therapy for multiple sclerosis. Neurology 2013, 80, 55–61.
-
(2013)
Neurology
, vol.80
, pp. 55-61
-
-
Cossburn, M.D.1
Harding, K.2
Ingram, G.3
El-Shanawany, T.4
Heaps, A.5
Pickersgill, T.P.6
Jolles, S.7
Robertson, N.P.8
-
101
-
-
84937476750
-
Safety of using disease-modifying therapy post-alemtuzumab treatment in patients with relapsing-remitting multiple sclerosis in the core and extensions phases of CAMMS223, CARE-MS I, and CARE-MS II studies
-
Philadelphia, PA, USA, 26 April–3 May
-
Edwards, K.; LaGanke, C.; Oyuela, P.; Palmer, J.; Margolin, D. Safety of using disease-modifying therapy post-alemtuzumab treatment in patients with relapsing-remitting multiple sclerosis in the core and extensions phases of CAMMS223, CARE-MS I, and CARE-MS II studies. In Proceedings of the AAN Meeting, Philadelphia, PA, USA, 26 April–3 May 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Edwards, K.1
Laganke, C.2
Oyuela, P.3
Palmer, J.4
Margolin, D.5
-
102
-
-
84937476751
-
Characterization of a next-generation anti-CD52 antibody
-
Washington, DC, USA, 18–25 April
-
Siders, W.M.; Greene, B.; McVie-Wylie, A.; Bailey, M.; Dhawan, V.; Boutin, P.; Best, A.; Lawendowski, C.; Turner, M.; Roberts, B., et al. Characterization of a next-generation anti-CD52 antibody. In Proceedings of the AAN Meeting, Washington, DC, USA, 18–25 April 2015.
-
(2015)
Proceedings of the AAN Meeting
-
-
Siders, W.M.1
Greene, B.2
McVie-Wylie, A.3
Bailey, M.4
Dhawan, V.5
Boutin, P.6
Best, A.7
Lawendowski, C.8
Turner, M.9
Roberts, B.10
-
103
-
-
77956209762
-
A novel strategy to reduce the immunogenicity of biological therapies
-
Somerfield, J.; Hill-Cawthorne, G.A.; Lin, A.; Zandi, M.S.; McCarthy, C.; Jones, J.L.; Willcox, M.; Shaw, D.; Thompson, S.A.; Compston, A.S., et al. A novel strategy to reduce the immunogenicity of biological therapies. J. Immunol. 2010, 185, 763–768.
-
(2010)
J. Immunol
, vol.185
, pp. 763-768
-
-
Somerfield, J.1
Hill-Cawthorne, G.A.2
Lin, A.3
Zandi, M.S.4
McCarthy, C.5
Jones, J.L.6
Willcox, M.7
Shaw, D.8
Thompson, S.A.9
Compston, A.S.10
-
104
-
-
84937436273
-
Long-term efficacy of alemtuzumab in polymyositis
-
Ruck, T.; Bittner, S.; Kuhlmann, T.; Wiendl, H.; Meuth, S.G. Long-term efficacy of alemtuzumab in polymyositis. Rheumatology (Oxford) 2015, 54, 560–562.
-
(2015)
Rheumatology (Oxford)
, vol.54
, pp. 560-562
-
-
Ruck, T.1
Bittner, S.2
Kuhlmann, T.3
Wiendl, H.4
Meuth, S.G.5
-
105
-
-
67649399221
-
Effect of alemtuzumab (Campath-1H) in patients with inclusion-body myositis
-
Dalakas, M.C.; Rakocevic, G.; Schmidt, J.; Salajegheh, M.; McElroy, B.; Harris-Love, M.O.; Shrader, J.A.; Levy, E.W.; Dambrosia, J.; Kampen, R.L., et al. Effect of alemtuzumab (Campath-1H) in patients with inclusion-body myositis. Brain 2009, 132, 1536–1544.
-
(2009)
Brain
, vol.132
, pp. 1536-1544
-
-
Dalakas, M.C.1
Rakocevic, G.2
Schmidt, J.3
Salajegheh, M.4
McElroy, B.5
Harris-Love, M.O.6
Shrader, J.A.7
Levy, E.W.8
Dambrosia, J.9
Kampen, R.L.10
|