Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells

Journal of Experimental Medicine

Volumn 197, Issue 8, 2003, Pages 1007-1016

  Kassiotis, George ^a   Zamoyska, Rose ^a   Stockinger, Brigitta ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

CD4 positive T lymphocytes; Immunological memory; Major histocompatibility complex; T cell receptor

Indexed keywords

INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL KINETICS; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENSITY; FLOW CYTOMETRY; HOMEOSTASIS; IMMUNOLOGICAL MEMORY; LYMPHOCYTOPENIA; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODY AFFINITY; ANTIGENS, CD5; CD4-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CELL SURVIVAL; HISTOCOMPATIBILITY ANTIGENS; HOMEOSTASIS; IMMUNOLOGIC MEMORY; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, INTERLEUKIN-7; SIGNAL TRANSDUCTION;

EID: 0037460071     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021812     Document Type: Article

References (45)

1. Freitas, A.A., and B. Rocha. 2000. Population biology of lymphocytes: the flight for survival. Annu. Rev. Immunol 18:83-111.
2. Raff, M.C. 1992. Social controls on cell survival and cell death. Nature. 356:397-400.
3. + T cells, but affect their long-term life span. Immunity. 5:217-228.
4. Tanchot, C., F.A. Lemonnier, B. Perarnau, A.A. Freitas, and B. Rocha. 1997. Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science. 276:2057-2062.
5. Kirberg, J., A. Berns, and H. von Boehmer. 1997. Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules. J. Exp. Med. 186:1269-1275.
6. Brocker, T. 1997. Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class IIexpressing dendritic cells. J. Exp. Med. 186:1223-1232.
7. Rooke, R., C. Waltzinger, C. Benoist, and D. Mathis. 1997. Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses. Immunity. 7:123-134.
8. Witherden, D., N. van Oers, C. Waltzinger, A. Weiss, C. Benoist, and D. Mathis. 2000. Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules. J. Exp. Med. 191:355-364.
9. Seddon, B., G. Legname, P. Tomlinson, and R. Zamoyska. 2000. Long-term survival but impaired homeostatic proliferation of Naive T cells in the absence of p561ck. Science. 290:127-131.
10. Labrecque, N., L.S. Whitfield, R. Obst, C. Waltzinger, C. Benoist, and D. Mathis. 2001. How much TCR, does a T cell need? Immunity, 15:71-82.
11. Polic, B., D. Kunkel, A. Scheffold, and K. Rajewsky. 2001. How alpha beta T cells deal with induced TCR alpha ablation. Proc. Natl. Acad. Sci. USA. 98:8744-8749.
12. Murali-Krishna, K., L.L. Lau, S. Sambhara, F. Lemonnier, J. Altman, and R. Ahmed. 1999. Persistence of memory CD8 T cells in MHC class I-deficient mice. Science. 286:1377-1381.
13. Swain, S.L., H. Hu, and G. Huston. 1999. Class II-independent generation of CD4 memory T cells from effectors. Science. 286:1381-1383.
14. Kassiotis, G., S. Garcia, E. Simpson, and B. Stockinger. 2002. Impairment of imnmnological memory in the absence of MHC despite survival of memory T cells. Nat. Immunol. 3:244-250.
15. Schluns, K.S., W.C. Kieper, S.C. Jameson, and L. Lefrancois. 2000. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 1:426-432.
16. Vivien, L., C. Benoist, and D. Mathis. 2001. T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo. Int. Immunol. 13:763-768.
17. Tan, J.T., E. Dudl, E. LeRoy, R. Murray, J. Sprent, K.I. Weinberg, and C.D. Surh. 2001. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc. Natl. Acad. Sci. USA. 98:8732-8737.
18. + T cells. Nat. Immunol. 1:107-111.
19. Lantz, O., I. Grandjean, P. Matzinger, and J.P. Di Santo. 2000. Gamma chain required for naive CD4+ T cell survival but not for antigen proliferation. Nat. Immunol. 1:54-58.
20. Tan, J.T., B. Ernst, W.C. Kieper, E. LeRoy, J. Sprent, and C.D. Surh. 2002. Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8(+) cells but are not required for memory phenotype CD4(+) cells. J. Exp. Med. 195:1523-1532.
21. Barthlott, T., R.J. Wright, and B. Stockinger. 1998. Normal thymic selection of TCR transgenic CD4 T cells, but impaired survival in the periphery despite the presence of selecting MHC molecules. J. Immunol. 161:3992-3999.
22. Tanchot, C., A. Le Campion, S. Leaument, N. Dautigny, and B. Lucas. 2001. Naive CD4(+) lymphocytes convert to anergic of memory-like cells in T cell-deprived recipients. Eur. J. Immunol. 31:2256-2265.
23. Rocha, B., and H. von Boehmer. 1991. Peripheral selection of the T cell repertoire. Science. 251:1225-1228.
24. Viret, C., F.S. Wong, and C.A.J. Janeway. 1999. Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition. Immunity. 10:559-568.
25. Ernst, B., D.S. Lee, J.M. Chang, J. Sprent, and C.D. Surh. 1999. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity. 11:173-181.
26. Ferreira, C., T. Barthlott, S. Garcia, R. Zamoyska, and B. Stockinger. 2000. Differential survival of naive CD4 and CD8 T cells. J. Immunol. 165:3689-3694.
27. Ge, Q., V.P. Rao, B.K. Cho, H.N. Eisen, and J. Chen. 2001. Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/MHC epitopes and strength of their interaction with T cell receptors. Proc. Natl. Acad. Sci. USA. 98:1728-1733.
28. Strong, J., Q. Wang, and N. Killeen. 2001. Impaired survival of T helper cells in the absence of CD4. Proc. Natl. Acad. Sci. USA. 98:2566-2571.
29. Wang, Q., J. Strong, and N. Killeen. 2001. Homeostatic competition among T cells revealed by conditional inactivation of the mouse Cd4 gene. J. Exp. Med. 194:1721-1730.
30. Zal, T., A. Volkmann, and B. Stockinger. 1994. Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen. J. Exp. Med. 180:2089-2099.
31. + T cells or B cells. J. Immunol. 161:1868-1874.
32. + T cells in transgenic mice expressing a class II MHCrestricted antigen receptor. Nature. 341:746-749.
33. Almeida, A.R., J.A. Borghans, and A.A. Freitas. 2001. T cell homeostasis: thymus regeneration and peripheral T cell restoration in mice with a reduced fraction of competent precursors. J. Exp. Med. 194:591-599.
34. Smith, K., B. Seddon, M.A. Purbhoo, R. Zamoyska, A.G. Fisher, and M. Merkenschlager. 2001. Sensory, adaptation in naive peripheral CD4 T cells. J. Exp. Med. 194:1253-1261.
35. Markiewicz, M.A., C. Girao, J.T. Opferman, J. Sun, Q. Hu, A.A. Agulnik, C.E. Bishop, C.B. Thompson, and P.G. Ashton-Rickardt. 1998. Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules. Proc. Natl. Acad. Sci. USA. 95:3065-3070.
36. Garcia, S., J. DiSanto, and B. Stockinger. 1999. Following the development of a CD4 T cell response in vivo: from activation to memory formation. Immunity. 11:163-171.
37. Jameson, S.C., K.A. Hogquist, and M.J. Bevan. 1995. Positive selection of thymocytes. Annu. Rev. Immunol. 13:93-126.
38. Grossman, Z., and W.E. Paul. 2001. Autoreactivity, dynamic tuning and selectivity. Curr. Opin. Immunol. 13:687-698.
39. Azzam, H.S., A. Grinberg, K. Lui, H. Shen, E.W. Shores, and P.E. Love. 1998. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCK avidity. J. Exp. Med. 188:2301-2311.
40. Wong, P., G.M. Barton, K.A. Forbush, and A.Y. Rudelisky. 2001. Dynamic tuning of T cell reactivity by self-peptidemajor histocompatibility complex ligands. J. Exp. Med. 193:1179-1187.
41. Fahmy, T.M., J.G. Bieler, M. Edidin, and J.P. Schneck. 2001. Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen. Immunity. 14:135-143.
42. Slifka, M.K., and J.L. Whitton. 2001. Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR. Nat. Immunol. 2:711-717.
43. Lin, M.Y., and R.M. Welsh. 1998. Stability and diversity of T cell receptor repertoire usage during lymphocytic choriomeningitis virus infection of mice. J. Exp. Med. 188:1993-2005.
44. Blattman, J.N., D.J. Sourdive, K. Murali-Krishna, R. Ahmed, and J.D. Altman. 2000. Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection. J. Immunol. 165:6081-6090.
45. Fasso, M., N. Anandasabapathy, F. Crawford, J. Kappler, C.G. Fathman, and W.M. Ridgway. 2000. T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo. J. Exp. Med. 192:1719-1730.