메뉴 건너뛰기




Volumn 10, Issue 13, 2015, Pages 2093-2107

Nanocarriers for treatment of ocular neovascularization in the back of the eye: New vehicles for ophthalmic drug delivery

Author keywords

drug delivery; eye; nanocarriers; ocular neovascularization

Indexed keywords

DENDRIMER; DRUG VEHICLE; GOLD NANOPARTICLE; METAL NANOPARTICLE; NANOCARRIER; NANOPARTICLE; SILICA NANOPARTICLE; SILVER NANOPARTICLE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; VASCULOTROPIN; DRUG; DRUG CARRIER; EYE DROPS;

EID: 84937485036     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.15.47     Document Type: Review
Times cited : (51)

References (82)
  • 1
    • 33947308503 scopus 로고    scopus 로고
    • Retinopathy of prematurity
    • Chen J, Smith LE. Retinopathy of prematurity. Angiogenesis 10(2), 133-140 (2007).
    • (2007) Angiogenesis , vol.10 , Issue.2 , pp. 133-140
    • Chen, J.1    Smith, L.E.2
  • 4
    • 70350148188 scopus 로고    scopus 로고
    • Nanocarriers in ocular drug delivery: An update review
    • Wadhwa S, Paliwal R, Paliwal SR, Vyas SP. Nanocarriers in ocular drug delivery: an update review. Curr. Pharm. Des. 15(23), 2724-2750 (2009).
    • (2009) Curr. Pharm. Des. , vol.15 , Issue.23 , pp. 2724-2750
    • Wadhwa, S.1    Paliwal, R.2    Paliwal, S.R.3    Vyas, S.P.4
  • 6
    • 78149271741 scopus 로고    scopus 로고
    • Smaller birth size is associated with narrower retinal arterioles in early adolescence
    • Gopinath B, Baur LA, Wang JJ et al. Smaller birth size is associated with narrower retinal arterioles in early adolescence. Microcirculation 17(8), 660-668 (2010).
    • (2010) Microcirculation , vol.17 , Issue.8 , pp. 660-668
    • Gopinath, B.1    Baur, L.A.2    Wang, J.J.3
  • 7
    • 79955767110 scopus 로고    scopus 로고
    • Emerging therapeutic approaches in the management of retinal angiogenesis and edema
    • Truong A, Wong TY, Khachigian LM. Emerging therapeutic approaches in the management of retinal angiogenesis and edema. J. Mol. Med. (Berl.) 89(4), 343-361 (2011).
    • (2011) J. Mol. Med. (Berl.) , vol.89 , Issue.4 , pp. 343-361
    • Truong, A.1    Wong, T.Y.2    Khachigian, L.M.3
  • 8
    • 84881336175 scopus 로고    scopus 로고
    • Ocular neovascularization
    • Campochiaro PA. Ocular neovascularization. J. Mol. Med. (Berl.) 91(3), 311-321 (2013).
    • (2013) J. Mol. Med. (Berl.) , vol.91 , Issue.3 , pp. 311-321
    • Campochiaro, P.A.1
  • 9
    • 77955013602 scopus 로고    scopus 로고
    • Diabetic retinopathy
    • Cheung N, Mitchell P, Wong TY. Diabetic retinopathy. Lancet 376(9735), 124-136 (2010).
    • (2010) Lancet , vol.376 , Issue.9735 , pp. 124-136
    • Cheung, N.1    Mitchell, P.2    Wong, T.Y.3
  • 10
    • 69249174238 scopus 로고    scopus 로고
    • Vitreous levels of erythropoietin and vascular endothelial growth factor in eyes with retinopathy of prematurity
    • Sato T, Kusaka S, Shimojo H, Fujikado T. Vitreous levels of erythropoietin and vascular endothelial growth factor in eyes with retinopathy of prematurity. Ophthalmology 116(9), 1599-1603 (2009).
    • (2009) Ophthalmology , vol.116 , Issue.9 , pp. 1599-1603
    • Sato, T.1    Kusaka, S.2    Shimojo, H.3    Fujikado, T.4
  • 11
    • 84872021668 scopus 로고    scopus 로고
    • Vascular endothelial growth factor A in intraocular vascular disease
    • Miller JW, Le Couter J, Strauss EC, Ferrara N. Vascular endothelial growth factor A in intraocular vascular disease. Ophthalmology 120(1), 106-114 (2013).
    • (2013) Ophthalmology , vol.120 , Issue.1 , pp. 106-114
    • Miller, J.W.1    Le Couter, J.2    Strauss, E.C.3    Ferrara, N.4
  • 12
    • 84994069913 scopus 로고    scopus 로고
    • Structure, function, and pathology of bruch's membrane
    • Curcio CA, Johnson M. Structure, function, and pathology of bruch's membrane. Elastic 146(152), 210-213 (2012).
    • (2012) Elastic , vol.146 , Issue.152 , pp. 210-213
    • Curcio, C.A.1    Johnson, M.2
  • 13
    • 84887374665 scopus 로고    scopus 로고
    • Treatment of age-related macular degeneration
    • Cheung CM, Wong TY. Treatment of age-related macular degeneration. Lancet 382(9900), 1230-1232 (2013).
    • (2013) Lancet , vol.382 , Issue.9900 , pp. 1230-1232
    • Cheung, C.M.1    Wong, T.Y.2
  • 14
    • 84923307650 scopus 로고    scopus 로고
    • Myopic choroidal neovascularisation: Current concepts and update on clinical management
    • Wong TY, Ohno-Matsui K, Leveziel N et al. Myopic choroidal neovascularisation: current concepts and update on clinical management. Br. J. Ophthalmol. 99(3), 289-296 (2014).
    • (2014) Br. J. Ophthalmol. , vol.99 , Issue.3 , pp. 289-296
    • Wong, T.Y.1    Ohno-Matsui, K.2    Leveziel, N.3
  • 16
    • 84904357863 scopus 로고    scopus 로고
    • Aqueous vascular endothelial growth factor and ranibizumab concentrations after monthly and bimonthly intravitreal injections of ranibizumab for age-related macular degeneration
    • Wang X, Sawada T, Kakinoki M et al. Aqueous vascular endothelial growth factor and ranibizumab concentrations after monthly and bimonthly intravitreal injections of ranibizumab for age-related macular degeneration. Graefes Arch. Clin. Exp. Ophthalmol. 252(7), 1033-1039 (2014).
    • (2014) Graefes Arch. Clin. Exp. Ophthalmol. , vol.252 , Issue.7 , pp. 1033-1039
    • Wang, X.1    Sawada, T.2    Kakinoki, M.3
  • 17
    • 84911988207 scopus 로고    scopus 로고
    • Systemic pharmacokinetics following intravitreal injections of ranibizumab, bevacizumab or aflibercept in patients with neovascular AMD
    • Avery RL, Castellarin AA, Steinle NC et al. Systemic pharmacokinetics following intravitreal injections of ranibizumab, bevacizumab or aflibercept in patients with neovascular AMD. Br. J. Ophthalmol. 98(12), 1636-1641 (2014).
    • (2014) Br. J. Ophthalmol. , vol.98 , Issue.12 , pp. 1636-1641
    • Avery, R.L.1    Castellarin, A.A.2    Steinle, N.C.3
  • 18
    • 79955631484 scopus 로고    scopus 로고
    • Efficacy and safety of monthly versus quarterly ranibizumab treatment in neovascular age-related macular degeneration: The EXCITE study
    • Schmidt-Erfurth U, Eldem B, Guymer R et al. Efficacy and safety of monthly versus quarterly ranibizumab treatment in neovascular age-related macular degeneration: the EXCITE study. Ophthalmology 118(5), 831-839 (2011).
    • (2011) Ophthalmology , vol.118 , Issue.5 , pp. 831-839
    • Schmidt-Erfurth, U.1    Eldem, B.2    Guymer, R.3
  • 19
    • 84902078367 scopus 로고    scopus 로고
    • Diabetic macular edema: New concepts in patho-physiology and treatment
    • Zhang X, Zeng H, Bao S, Wang N, Gillies MC. Diabetic macular edema: new concepts in patho-physiology and treatment. Cell Biosci. 4, 27 (2014).
    • (2014) Cell Biosci. , vol.4 , pp. 27
    • Zhang, X.1    Zeng, H.2    Bao, S.3    Wang, N.4    Gillies, M.C.5
  • 22
    • 12844264109 scopus 로고    scopus 로고
    • Emulsified microemulsions and oil-containing liquid crystalline phases
    • Yaghmur A, De Campo L, Sagalowicz L, Leser ME, Glatter O. Emulsified microemulsions and oil-containing liquid crystalline phases. Langmuir 21(2), 569-577 (2005).
    • (2005) Langmuir , vol.21 , Issue.2 , pp. 569-577
    • Yaghmur, A.1    De Campo, L.2    Sagalowicz, L.3    Leser, M.E.4    Glatter, O.5
  • 25
    • 0036597855 scopus 로고    scopus 로고
    • EORTC 10968: A Phase i clinical and pharmacokinetic study of polyethylene glycol liposomal doxorubicin (Caelyx, Doxil) at a 6-week interval in patients with metastatic breast cancer
    • Hamilton A, Biganzoli L, Coleman R et al. EORTC 10968: a Phase I clinical and pharmacokinetic study of polyethylene glycol liposomal doxorubicin (Caelyx, Doxil) at a 6-week interval in patients with metastatic breast cancer. Ann. Oncol. 13(6), 910-918 (2002).
    • (2002) Ann. Oncol. , vol.13 , Issue.6 , pp. 910-918
    • Hamilton, A.1    Biganzoli, L.2    Coleman, R.3
  • 26
    • 0027517578 scopus 로고
    • Pharmacokinetics of DepoFoam gentamicin delivery system and effect on soft tissue infection
    • Grayson LS, Hansbrough JF, Zapata-Sirvent RL, Kim T, Kim S. Pharmacokinetics of DepoFoam gentamicin delivery system and effect on soft tissue infection. J. Surg. Res. 55(5), 559-564 (1993).
    • (1993) J. Surg. Res. , vol.55 , Issue.5 , pp. 559-564
    • Grayson, L.S.1    Hansbrough, J.F.2    Zapata-Sirvent, R.L.3    Kim, T.4    Kim, S.5
  • 27
    • 84873252557 scopus 로고    scopus 로고
    • Liposomal drug delivery systems: From concept to clinical applications
    • Allen TM, Cullis PR. Liposomal drug delivery systems: from concept to clinical applications. Adv. Drug Deliv. Rev. 65(1), 36-48 (2013).
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , Issue.1 , pp. 36-48
    • Allen, T.M.1    Cullis, P.R.2
  • 28
    • 84914162408 scopus 로고    scopus 로고
    • Nanoparticle-assisted targeted delivery of eye-specific genes to eyes significantly improves the vision of blind mice in vivo
    • Rajala A, Wang Y, Zhu Y et al. Nanoparticle-assisted targeted delivery of eye-specific genes to eyes significantly improves the vision of blind mice in vivo. Nano Lett. 14(9), 5257-5263 (2014).
    • (2014) Nano Lett. , vol.14 , Issue.9 , pp. 5257-5263
    • Rajala, A.1    Wang, Y.2    Zhu, Y.3
  • 29
    • 84863910976 scopus 로고    scopus 로고
    • Diclofenac/ biodegradable polymer micelles for ocular applications
    • Li X, Zhang Z, Li J, Sun S, Weng Y, Chen H. Diclofenac/ biodegradable polymer micelles for ocular applications. Nanoscale 4(15), 4667-4673 (2012).
    • (2012) Nanoscale , vol.4 , Issue.15 , pp. 4667-4673
    • Li, X.1    Zhang, Z.2    Li, J.3    Sun, S.4    Weng, Y.5    Chen, H.6
  • 30
    • 84866656642 scopus 로고    scopus 로고
    • Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration
    • Yang H, Tyagi P, Kadam RS, Holden CA, Kompella UB. Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration. ACS Nano 6(9), 7595-7606 (2012).
    • (2012) ACS Nano , vol.6 , Issue.9 , pp. 7595-7606
    • Yang, H.1    Tyagi, P.2    Kadam, R.S.3    Holden, C.A.4    Kompella, U.B.5
  • 31
    • 25444448098 scopus 로고    scopus 로고
    • Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity
    • Connor EE, Mwamuka J, Gole A, Murphy CJ, Wyatt MD. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 1(3), 325-327 (2005).
    • (2005) Small , vol.1 , Issue.3 , pp. 325-327
    • Connor, E.E.1    Mwamuka, J.2    Gole, A.3    Murphy, C.J.4    Wyatt, M.D.5
  • 32
    • 33746308120 scopus 로고    scopus 로고
    • Laser-induced release of encapsulated materials inside living cells
    • Skirtach AG, Javier AM, Kreft O et al. Laser-induced release of encapsulated materials inside living cells. Angew. Chem. Int. Ed. Engl. 45(28), 4612-4617 (2006).
    • (2006) Angew. Chem. Int. Ed. Engl. , vol.45 , Issue.28 , pp. 4612-4617
    • Skirtach, A.G.1    Javier, A.M.2    Kreft, O.3
  • 33
    • 77951296547 scopus 로고    scopus 로고
    • Intravenously administered gold nanoparticles pass through the blood-retinal barrier depending on the particle size, and induce no retinal toxicity
    • Kim JH, Kim JH, Kim KW, Kim MH, Yu YS. Intravenously administered gold nanoparticles pass through the blood-retinal barrier depending on the particle size, and induce no retinal toxicity. Nanotechnology 20(50), 505101 (2009).
    • (2009) Nanotechnology , vol.20 , Issue.50 , pp. 505101
    • Kim, J.H.1    Kim, J.H.2    Kim, K.W.3    Kim, M.H.4    Yu, Y.S.5
  • 34
    • 84872360422 scopus 로고    scopus 로고
    • Silica nanoparticles-induced cytotoxicity, oxidative stress and apoptosis in cultured A431 and A549 cells
    • Ahamed M. Silica nanoparticles-induced cytotoxicity, oxidative stress and apoptosis in cultured A431 and A549 cells. Human Exp. Toxicol. 32(2), 186-195 (2013).
    • (2013) Human Exp. Toxicol. , vol.32 , Issue.2 , pp. 186-195
    • Ahamed, M.1
  • 35
    • 77956945642 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles for intracellular controlled drug delivery
    • Vivero-Escoto JL, Slowing Ii, Trewyn BG, Lin VSY. Mesoporous silica nanoparticles for intracellular controlled drug delivery. Small 6(18), 1952-1967 (2010).
    • (2010) Small , vol.6 , Issue.18 , pp. 1952-1967
    • Vivero-Escoto, J.L.1    Slowing, I.I.2    Trewyn, B.G.3    Lin, V.S.Y.4
  • 36
    • 46749123819 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers
    • Slowing II, Vivero-Escoto JL, Wu CW, Lin VSY. Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Adv. Drug Deliv. Rev. 60(11), 1278-1288 (2008).
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , Issue.11 , pp. 1278-1288
    • Slowing, I.I.1    Vivero-Escoto, J.L.2    Wu, C.W.3    Lin, V.S.Y.4
  • 37
    • 0035054842 scopus 로고    scopus 로고
    • Iron nanoparticles as potential magnetic carriers
    • Carpenter EE. Iron nanoparticles as potential magnetic carriers. J. Magn. Magnet. Mater. 225(1), 17-20 (2001).
    • (2001) J. Magn. Magnet. Mater. , vol.225 , Issue.1 , pp. 17-20
    • Carpenter, E.E.1
  • 38
    • 2442683843 scopus 로고    scopus 로고
    • Magnetically modulated therapeutic systems
    • Häfeli U. Magnetically modulated therapeutic systems. Int. J. Pharmaceut. 277(1), 19-24 (2004).
    • (2004) Int. J. Pharmaceut. , vol.277 , Issue.1 , pp. 19-24
    • Häfeli, U.1
  • 40
    • 84865527543 scopus 로고    scopus 로고
    • Focused magnetic stem cell targeting to the retina using superparamagnetic iron oxide nanoparticles
    • Yanai A, Hafeli UO, Metcalfe AL et al. Focused magnetic stem cell targeting to the retina using superparamagnetic iron oxide nanoparticles. Cell Transplant. 21(6), 1137-1148 (2012).
    • (2012) Cell Transplant. , vol.21 , Issue.6 , pp. 1137-1148
    • Yanai, A.1    Hafeli, U.O.2    Metcalfe, A.L.3
  • 42
    • 34247215173 scopus 로고    scopus 로고
    • Drug delivery methods for posterior segment disease
    • Hsu J. Drug delivery methods for posterior segment disease. Curr. Opin. Ophthalmol. 18(3), 235-239 (2007).
    • (2007) Curr. Opin. Ophthalmol. , vol.18 , Issue.3 , pp. 235-239
    • Hsu, J.1
  • 43
    • 0022852854 scopus 로고
    • Topical ocular drug delivery: Recent developments and future challenges
    • Lee VH, Robinson JR. Topical ocular drug delivery: recent developments and future challenges. J. Ocul. Pharmacol. 2(1), 67-108 (1986).
    • (1986) J. Ocul. Pharmacol. , vol.2 , Issue.1 , pp. 67-108
    • Lee, V.H.1    Robinson, J.R.2
  • 44
    • 0036669505 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment from drops
    • Maurice DM. Drug delivery to the posterior segment from drops. Surv. Ophthalmol. 47(Suppl. 1), S41-S52 (2002).
    • (2002) Surv. Ophthalmol. , vol.47 , pp. S41-S52
    • Maurice, D.M.1
  • 45
    • 84874679837 scopus 로고    scopus 로고
    • Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers
    • Gan L, Wang J, Jiang M et al. Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers. Drug Discov. Today 18(5-6), 290-297 (2013).
    • (2013) Drug Discov. Today , vol.18 , Issue.5-6 , pp. 290-297
    • Gan, L.1    Wang, J.2    Jiang, M.3
  • 47
    • 67349119829 scopus 로고    scopus 로고
    • Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV
    • Singh SR, Grossniklaus HE, Kang SJ, Edelhauser HF, Ambati BK, Kompella UB. Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV. Gene Ther. 16(5), 645-659 (2009).
    • (2009) Gene Ther. , vol.16 , Issue.5 , pp. 645-659
    • Singh, S.R.1    Grossniklaus, H.E.2    Kang, S.J.3    Edelhauser, H.F.4    Ambati, B.K.5    Kompella, U.B.6
  • 48
    • 67650424032 scopus 로고    scopus 로고
    • Safety of repeat intravitreal injections of bevacizumab versus ranibizumab: Our experience after 2,000 injections
    • Ladas ID, Karagiannis DA, Rouvas AA, Kotsolis AI, Liotsou A, Vergados I. Safety of repeat intravitreal injections of bevacizumab versus ranibizumab: our experience after 2,000 injections. Retina 29(3), 313-318 (2009).
    • (2009) Retina , vol.29 , Issue.3 , pp. 313-318
    • Ladas, I.D.1    Karagiannis, D.A.2    Rouvas, A.A.3    Kotsolis, A.I.4    Liotsou, A.5    Vergados, I.6
  • 49
    • 0035113020 scopus 로고    scopus 로고
    • Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis
    • Young S, Larkin G, Branley M, Lightman S. Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis. Clin. Experiment. Ophthalmol. 29(1), 2-6 (2001).
    • (2001) Clin. Experiment. Ophthalmol. , vol.29 , Issue.1 , pp. 2-6
    • Young, S.1    Larkin, G.2    Branley, M.3    Lightman, S.4
  • 50
    • 0042844771 scopus 로고    scopus 로고
    • Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles
    • Bourges JL, Gautier SE, Delie F et al. Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles. Invest. Ophthalmol. Vis. Sci. 44(8), 3562-3569 (2003).
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , Issue.8 , pp. 3562-3569
    • Bourges, J.L.1    Gautier, S.E.2    Delie, F.3
  • 51
    • 84862989504 scopus 로고    scopus 로고
    • Intravitreal poly(l-lactide) microparticles sustain retinal and choroidal delivery of TG-0054, a hydrophilic drug intended for neovascular diseases
    • Shelke NB, Kadam R, Tyagi P, Rao VR, Kompella UB. Intravitreal poly(l-lactide) microparticles sustain retinal and choroidal delivery of TG-0054, a hydrophilic drug intended for neovascular diseases. Drug Deliv. Transl. Res. 1(1), 76-90 (2011).
    • (2011) Drug Deliv. Transl. Res. , vol.1 , Issue.1 , pp. 76-90
    • Shelke, N.B.1    Kadam, R.2    Tyagi, P.3    Rao, V.R.4    Kompella, U.B.5
  • 53
    • 1042301272 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye III: The effect of parallel elimination pathway on the vitreous drug level after subconjunctival injection
    • Lee TW, Robinson JR. Drug delivery to the posterior segment of the eye III: the effect of parallel elimination pathway on the vitreous drug level after subconjunctival injection. J. Ocul. Pharmacol. Ther. 20(1), 55-64 (2004).
    • (2004) J. Ocul. Pharmacol. Ther. , vol.20 , Issue.1 , pp. 55-64
    • Lee, T.W.1    Robinson, J.R.2
  • 54
    • 28644432836 scopus 로고    scopus 로고
    • Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration
    • Amrite AC, Kompella UB. Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration. J. Pharm. Pharmacol. 57(12), 1555-1563 (2005).
    • (2005) J. Pharm. Pharmacol. , vol.57 , Issue.12 , pp. 1555-1563
    • Amrite, A.C.1    Kompella, U.B.2
  • 56
    • 78650996703 scopus 로고    scopus 로고
    • The inhibition of retinal neovascularization by gold nanoparticles via suppression of VEGFR-2 activation
    • Kim JH, Kim MH, Jo DH, Yu YS, Lee TG, Kim JH. The inhibition of retinal neovascularization by gold nanoparticles via suppression of VEGFR-2 activation. Biomaterials 32(7), 1865-1871 (2011).
    • (2011) Biomaterials , vol.32 , Issue.7 , pp. 1865-1871
    • Kim, J.H.1    Kim, M.H.2    Jo, D.H.3    Yu, Y.S.4    Lee, T.G.5    Kim, J.H.6
  • 57
    • 84925270815 scopus 로고    scopus 로고
    • Topically administered gold nanoparticles inhibit experimental corneal neovascularization in mice
    • Cho WK, Kang S, Choi H, Rho CR. Topically administered gold nanoparticles inhibit experimental corneal neovascularization in mice. Cornea 34(4), 456-459 (2015).
    • (2015) Cornea , vol.34 , Issue.4 , pp. 456-459
    • Cho, W.K.1    Kang, S.2    Choi, H.3    Rho, C.R.4
  • 58
    • 67650455894 scopus 로고    scopus 로고
    • Silver nanoparticles inhibit VEGF induced cell proliferation and migration in bovine retinal endothelial cells
    • Kalishwaralal K, Banumathi E, Ram Kumar Pandian S et al. Silver nanoparticles inhibit VEGF induced cell proliferation and migration in bovine retinal endothelial cells. Colloids Surf. B Biointerfaces 73(1), 51-57 (2009).
    • (2009) Colloids Surf. B Biointerfaces , vol.73 , Issue.1 , pp. 51-57
    • Kalishwaralal, K.1    Banumathi, E.2    Ram Kumar Pandian, S.3
  • 61
    • 84862685176 scopus 로고    scopus 로고
    • Antiangiogenic effect of silicate nanoparticle on retinal neovascularization induced by vascular endothelial growth factor
    • Jo DH, Kim JH, Yu YS, Lee TG, Kim JH. Antiangiogenic effect of silicate nanoparticle on retinal neovascularization induced by vascular endothelial growth factor. Nanomedicine 8(5), 784-791 (2012).
    • (2012) Nanomedicine , vol.8 , Issue.5 , pp. 784-791
    • Jo, D.H.1    Kim, J.H.2    Yu, Y.S.3    Lee, T.G.4    Kim, J.H.5
  • 62
    • 84872852457 scopus 로고    scopus 로고
    • Choroidal neovascularization reduced by targeted drug delivery with cationic liposome-encapsulated paclitaxel or targeted photodynamic therapy with verteporfin encapsulated in cationic liposomes
    • Gross N, Ranjbar M, Evers C et al. Choroidal neovascularization reduced by targeted drug delivery with cationic liposome-encapsulated paclitaxel or targeted photodynamic therapy with verteporfin encapsulated in cationic liposomes. Mol. Vis. 19, 54-61 (2013).
    • (2013) Mol. Vis. , vol.19 , pp. 54-61
    • Gross, N.1    Ranjbar, M.2    Evers, C.3
  • 63
    • 84873941177 scopus 로고    scopus 로고
    • Flt1 peptide-hyaluronate conjugate micelle-like nanoparticles encapsulating genistein for the treatment of ocular neovascularization
    • Kim H, Choi JS, Kim KS, Yang JA, Joo CK, Hahn SK. Flt1 peptide-hyaluronate conjugate micelle-like nanoparticles encapsulating genistein for the treatment of ocular neovascularization. Acta Biomaterialia 8(11), 3932-3940 (2012).
    • (2012) Acta Biomaterialia , vol.8 , Issue.11 , pp. 3932-3940
    • Kim, H.1    Choi, J.S.2    Kim, K.S.3    Yang, J.A.4    Joo, C.K.5    Hahn, S.K.6
  • 64
    • 68049142424 scopus 로고    scopus 로고
    • Nanoparticle-mediated expression of an angiogenic inhibitor ameliorates ischemiainduced retinal neovascularization and diabetes-induced retinal vascular leakage
    • Park K, Chen Y, Hu Y et al. Nanoparticle-mediated expression of an angiogenic inhibitor ameliorates ischemiainduced retinal neovascularization and diabetes-induced retinal vascular leakage. Diabetes 58(8), 1902-1913 (2009).
    • (2009) Diabetes , vol.58 , Issue.8 , pp. 1902-1913
    • Park, K.1    Chen, Y.2    Hu, Y.3
  • 65
    • 82655179959 scopus 로고    scopus 로고
    • Gene transfer using micellar nanovectors inhibits choroidal neovascularization in vivo
    • Iriyama A, Oba M, Ishii T et al. Gene transfer using micellar nanovectors inhibits choroidal neovascularization in vivo. PLoS ONE 6(12), e28560 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.12 , pp. e28560
    • Iriyama, A.1    Oba, M.2    Ishii, T.3
  • 66
    • 84861592634 scopus 로고    scopus 로고
    • Novel micelle carriers for cyclosporin A topical ocular delivery: In vivo cornea penetration, ocular distribution and efficacy studies
    • Di Tommaso C, Bourges JL, Valamanesh F et al. Novel micelle carriers for cyclosporin A topical ocular delivery: in vivo cornea penetration, ocular distribution and efficacy studies. Eur. J. Pharm. Biopharm. 81(2), 257-264 (2012).
    • (2012) Eur. J. Pharm. Biopharm. , vol.81 , Issue.2 , pp. 257-264
    • Di Tommaso, C.1    Bourges, J.L.2    Valamanesh, F.3
  • 67
    • 84880511751 scopus 로고    scopus 로고
    • Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide
    • Shmueli RB, Ohnaka M, Miki A et al. Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide. Biomaterials 34(30), 7544-7551 (2013).
    • (2013) Biomaterials , vol.34 , Issue.30 , pp. 7544-7551
    • Shmueli, R.B.1    Ohnaka, M.2    Miki, A.3
  • 68
    • 84887159636 scopus 로고    scopus 로고
    • Sustained delivery of a HIF-1 antagonist for ocular neovascularization
    • Iwase T, Fu J, Yoshida T et al. Sustained delivery of a HIF-1 antagonist for ocular neovascularization. J. Control. Release 172(3), 625-633 (2013).
    • (2013) J. Control. Release , vol.172 , Issue.3 , pp. 625-633
    • Iwase, T.1    Fu, J.2    Yoshida, T.3
  • 69
    • 36749059610 scopus 로고    scopus 로고
    • Inhibitory efficacy of intravitreal dexamethasone acetate-loaded PLGA nanoparticles on choroidal neovascularization in a laserinduced rat model
    • Xu J, Wang Y, Li Y et al. Inhibitory efficacy of intravitreal dexamethasone acetate-loaded PLGA nanoparticles on choroidal neovascularization in a laserinduced rat model. J. Ocul. Pharmacol. Ther. 23(6), 527-540 (2007).
    • (2007) J. Ocul. Pharmacol. Ther. , vol.23 , Issue.6 , pp. 527-540
    • Xu, J.1    Wang, Y.2    Li, Y.3
  • 70
    • 84876521481 scopus 로고    scopus 로고
    • Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration
    • Luo L, Zhang X, Hirano Y et al. Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration. ACS Nano 7(4), 3264-3275 (2013).
    • (2013) ACS Nano , vol.7 , Issue.4 , pp. 3264-3275
    • Luo, L.1    Zhang, X.2    Hirano, Y.3
  • 71
    • 84933671554 scopus 로고    scopus 로고
    • Nanoparticle-mediated expression of a Wnt pathway inhibitor ameliorates ocular neovascularization
    • Wang Z, Cheng R, Lee K et al. Nanoparticle-mediated expression of a Wnt pathway inhibitor ameliorates ocular neovascularization. Arterioscler. Thromb. Vasc. Biol. 35(4), 855-864 (2015).
    • (2015) Arterioscler. Thromb. Vasc. Biol. , vol.35 , Issue.4 , pp. 855-864
    • Wang, Z.1    Cheng, R.2    Lee, K.3
  • 74
    • 35048842305 scopus 로고    scopus 로고
    • Liposomal drug delivery systems: An update review
    • Samad A, Sultana Y, Aqil M. Liposomal drug delivery systems: an update review. Curr. Drug Deliv. 4(4), 297-305 (2007).
    • (2007) Curr. Drug Deliv. , vol.4 , Issue.4 , pp. 297-305
    • Samad, A.1    Sultana, Y.2    Aqil, M.3
  • 75
    • 60849087935 scopus 로고    scopus 로고
    • Dual-drug delivery system based on hydrogel/micelle composites
    • Wei L, Cai C, Lin J, Chen T. Dual-drug delivery system based on hydrogel/micelle composites. Biomaterials 30(13), 2606-2613 (2009).
    • (2009) Biomaterials , vol.30 , Issue.13 , pp. 2606-2613
    • Wei, L.1    Cai, C.2    Lin, J.3    Chen, T.4
  • 76
    • 73649133678 scopus 로고    scopus 로고
    • Overcoming the barriers in micellar drug delivery: Loading efficiency, in vivo stability, and micelle-cell interaction
    • Kim S, Shi Y, Kim JY, Park K, Cheng JX. Overcoming the barriers in micellar drug delivery: loading efficiency, in vivo stability, and micelle-cell interaction. Expert Opin. Drug Deliv. 7(1), 49-62 (2010).
    • (2010) Expert Opin. Drug Deliv. , vol.7 , Issue.1 , pp. 49-62
    • Kim, S.1    Shi, Y.2    Kim, J.Y.3    Park, K.4    Cheng, J.X.5
  • 77
    • 33845218637 scopus 로고    scopus 로고
    • In vitro toxicity of silica nanoparticles in human lung cancer cells
    • Lin WS, Huang YW, Zhou XD, Ma YF. In vitro toxicity of silica nanoparticles in human lung cancer cells. Toxicol. Appl. Pharmacol. 217(3), 252-259 (2006).
    • (2006) Toxicol. Appl. Pharmacol. , vol.217 , Issue.3 , pp. 252-259
    • Lin, W.S.1    Huang, Y.W.2    Zhou, X.D.3    Ma, Y.F.4
  • 78
    • 77950850818 scopus 로고    scopus 로고
    • Impacts of mesoporous silica nanoparticle size, pore ordering, and pore integrity on hemolytic activity
    • Lin YS, Haynes CL. Impacts of mesoporous silica nanoparticle size, pore ordering, and pore integrity on hemolytic activity. J. Am. Chem. Soc. 132(13), 4834-4842 (2010).
    • (2010) J. Am. Chem. Soc. , vol.132 , Issue.13 , pp. 4834-4842
    • Lin, Y.S.1    Haynes, C.L.2
  • 79
    • 0037465976 scopus 로고    scopus 로고
    • Magnetite nanoparticle dispersions stabilized with triblock copolymers
    • Harris L, Goff J, Carmichael A et al. Magnetite nanoparticle dispersions stabilized with triblock copolymers. Chem. Mater. 15(6), 1367-1377 (2003).
    • (2003) Chem. Mater. , vol.15 , Issue.6 , pp. 1367-1377
    • Harris, L.1    Goff, J.2    Carmichael, A.3
  • 80
    • 0035874561 scopus 로고    scopus 로고
    • Synthesis and characterization of silica-coated iron oxide nanoparticles in microemulsion: The effect of nonionic surfactants
    • Santra S, Tapec R, Theodoropoulou N, Dobson J, Hebard A, Tan W. Synthesis and characterization of silica-coated iron oxide nanoparticles in microemulsion: the effect of nonionic surfactants. Langmuir 17(10), 2900-2906 (2001).
    • (2001) Langmuir , vol.17 , Issue.10 , pp. 2900-2906
    • Santra, S.1    Tapec, R.2    Theodoropoulou, N.3    Dobson, J.4    Hebard, A.5    Tan, W.6
  • 81
    • 1042277993 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye II: Development and validation of a simple pharmacokinetic model for subconjunctival injection
    • Lee TW, Robinson JR. Drug delivery to the posterior segment of the eye II: development and validation of a simple pharmacokinetic model for subconjunctival injection. J. Ocul. Pharmacol. Ther. 20(1), 43-53 (2004).
    • (2004) J. Ocul. Pharmacol. Ther. , vol.20 , Issue.1 , pp. 43-53
    • Lee, T.W.1    Robinson, J.R.2
  • 82
    • 0035676467 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye: Some insights on the penetration pathways after subconjunctival injection
    • Lee TW, Robinson JR. Drug delivery to the posterior segment of the eye: some insights on the penetration pathways after subconjunctival injection. J. Ocul. Pharmacol. Ther. 17(6), 565-572 (2001).
    • (2001) J. Ocul. Pharmacol. Ther. , vol.17 , Issue.6 , pp. 565-572
    • Lee, T.W.1    Robinson, J.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.