Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration

ACS Nano

Volumn 7, Issue 4, 2013, Pages 3264-3275

  Luo, Ling ^a,b   Zhang, Xiaohui ^a   Hirano, Yoshio ^c   Tyagi, Puneet ^d   Barabás, Péter ^a   Uehara, Hironori ^a   Miya, Tadashi R ^a   Singh, Nirbhai ^a   Archer, Bonnie ^a   Qazi, Yureeda ^a   Jackman, Kyle ^a   Das, Subrata K ^a   Olsen, Thomas ^a   Chennamaneni, Srinivas R ^a   Stagg, Brian C ^a   Ahmed, Faisal ^a   Emerson, Lyska ^a   Zygmunt, Kristen ^e   Whitaker, Ross ^e   Mamalis, Christina ^a   Huang, Wei ^a   Gao, Guangping ^f   Srinivas, Sangly P ^g   Krizaj, David ^a   Baffi, Judit ^c   Ambati, Jayakrishna ^c   Kompella, Uday B ^d   Ambati, Balamurali K ^a   more..

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b 306 HOSPITAL OF PLA   (China)

^c UNIVERSITY OF KENTUCKY   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY OF UTAH   (United States)

^f UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^g INDIANA UNIVERSITY   (United States)

Author keywords

angiogenesis; anti VEGF therapy; choroidal neovascularization models; gene delivery; nanoparticles

Indexed keywords

AGE-RELATED MACULAR DEGENERATION; ANGIOGENESIS; ANTI-VEGF THERAPY; BIODEGRADABLE NANOPARTICLE; CHOROIDAL NEOVASCULARIZATION; GENE DELIVERY; INTRAVENOUS INJECTIONS; NONVIRAL GENE THERAPY;

GENE TRANSFER; OPHTHALMOLOGY;

NANOPARTICLES;

DNA; NANOCAPSULE; VASCULOTROPIN RECEPTOR 1;

ANIMAL; ARTICLE; FIBROSIS; GENE THERAPY; GENETICS; HAPLORHINI; METHODOLOGY; MOUSE; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; RETINA; RETINA MACULA DEGENERATION; TREATMENT OUTCOME;

ANIMALS; DNA; FIBROSIS; GENETIC THERAPY; HAPLORHINI; MACULAR DEGENERATION; MICE; NANOCAPSULES; NEOVASCULARIZATION, PATHOLOGIC; RETINA; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 84876521481     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn305958y     Document Type: Article

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