TRPV1 sensitization mediates postinflammatory visceral pain following acute colitis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 309, Issue 2, 2015, Pages G87-G99

  Lapointe, Tamia K ^a   Basso, Lilian ^b,c,d   Iftinca, Mircea C ^a   Flynn, Robyn ^a   Chapman, Kevin ^a   Dietrich, Gilles ^b,c,d   Vergnolle, Nathalie ^a,b,c,d   Altier, Christophe ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

Inflammatory bowel disease; Peripheral sensitization; Substance P; Transient receptor potential vanilloid 1; Visceral pain

Indexed keywords

CAPSAICIN; DEXTRAN SULFATE; SUBSTANCE P; VANILLOID RECEPTOR 1; TRPV1 PROTEIN, MOUSE; VANILLOID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CELL SURFACE; COLITIS; CONTROLLED STUDY; DISEASE SEVERITY; GENE DELETION; HUMAN; HUMAN CELL; INFLAMMATION; LONG TERM EXPOSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSITIZATION; UBIQUITINATION; VISCERAL PAIN; ABDOMINAL PAIN; ACUTE DISEASE; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; CHEMICALLY INDUCED; COLON; DEFICIENCY; DISEASE MODEL; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; HYPERALGESIA; INNERVATION; KNOCKOUT MOUSE; METABOLISM; PAIN MEASUREMENT; PAIN THRESHOLD; PATHOPHYSIOLOGY; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION; TIME;

ABDOMINAL PAIN; ACUTE DISEASE; ANIMALS; BEHAVIOR, ANIMAL; COLITIS; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; HEK293 CELLS; HUMANS; HYPERALGESIA; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS, AFFERENT; PAIN MEASUREMENT; PAIN THRESHOLD; SIGNAL TRANSDUCTION; SUBSTANCE P; TIME FACTORS; TRANSFECTION; TRPV CATION CHANNELS; VISCERAL PAIN;

EID: 84937468375     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00421.2014     Document Type: Article

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