Ileitis modulates potassium and sodium currents in guinea pig dorsal root ganglia sensory neurons

Journal of Physiology

Volumn 552, Issue 3, 2003, Pages 797-807

  Stewart, Timothy ^a   Beyak, Michael J ^a   Vanner, Stephen ^a,b  

^a QUEEN S UNIVERSITY   (Canada)

^b HOTEL DIEU HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FAST BLUE; FLUORESCENT DYE; POTASSIUM CHANNEL; POTASSIUM ION; SODIUM ION; TETRODOTOXIN; TRINITROBENZENESULFONIC ACID;

ABDOMINAL PAIN; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SIZE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; FLUORESCENCE ANALYSIS; ILEITIS; MALE; NERVE CELL EXCITABILITY; NERVE ENDING; NOCICEPTION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SODIUM CURRENT; SPINAL GANGLION; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL ISOLATION; CURRENT DENSITY; GUINEA PIG; WHOLE CELL PATCH CLAMP;

ANIMALS; DRUG RESISTANCE; ELECTRIC CONDUCTIVITY; FEMALE; GANGLIA, SPINAL; GUINEA PIGS; ILEITIS; ION CHANNEL GATING; MALE; MODELS, BIOLOGICAL; NEURONS, AFFERENT; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SODIUM CHANNELS; TETRODOTOXIN; TRINITROBENZENESULFONIC ACID;

EID: 0242475152     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.046409     Document Type: Article

References (42)

1. Akins PT & McCleskey EW (1993). Characterization of potassium currents in adult rat sensory neurons and modulation by opioids and cyclic AMP. Neuroscience 56, 759-769.
2. Al Chaer ED, Kawasaki M & Pasricha PJ (2000). A new model of chronic visceral hypersensitivity in adult rats induced by colon irritation during postnatal development. Gastroenterology 119, 1276-1285.
3. Bielefeldt K, Ozaki N & Gebhart GF (2002a). Experimental ulcers alter voltage-sensitive sodium currents in rat gastric sensory neurons. Gastroenterology 122, 394-405.
4. Bielefeldt K, Ozaki N & Gebhart GF (2002b). Mild gastritis alters voltage-sensitive sodium currents in gastric sensory neurons in rats. Gastroenterology 122, 752-761.
5. Bielefeldt K, Ozaki N & Gebhart GF (2003). Role of nerve growth factor in modulation of gastric afferent neurons in the rat. Am J Physiol Gastrointest Liver Physiol 284, G499-507.
6. Blackshaw LA & Gebhart GF (2002). The pharmacology of gastrointestinal nociceptive pathways. Curr Opin Pharmacol 2, 642-649.
7. Cardenas LM, Cardenas CG & Scroggs RS (2001). 5HT increases excitability of nociceptor-like rat dorsal root ganglion neurons via cAMP-coupled TTX-resistant Na(+) channels. J Neurophysiol 86, 241-248.
8. Chadwick VS, Chen W, Shu D, Paulus B, Bethwaite P, Tie A & Wilson I (2002). Activation of the mucosal immune system in irritable bowel syndrome. Gastroenterology 122, 1778-1783.
9. Collins SM, Piche T & Rampal P (2001). The putative role of inflammation in the irritable bowel syndrome. Gut 49, 743-745.
10. Dib-Hajj S, Black JA, Cummins TR & Waxman SG (2002). NaN/Navl.9: a sodium channel with unique properties. Trends Neurosci 25, 253-259.
11. 2-induced inhibition of potassium currents in rat sensory neurones. J Physiol 516, 163-178.
12. Everill B, Rizzo MA & Kocsis JD (1998). Morphologically identified cutaneous afferent DRG neurons express three different potassium currents in varying proportions. J Neurophysiol 79, 1814-1824.
13. Fjell J, Cummins TR, Davis BM, Albers KM, Fried K, Waxman SG & Black JA (1999). Sodium channel expression in NGF-overexpressing transgenic mice. J Neurosci Res 57, 39-47.
14. Gebhart GF (2000). Pathobiology of visceral pain: molecular mechanisms and therapeutic implications IV. Visceral afferent contributions to the pathobiology of visceral pain. Am J Physiol Gastrointest Liver Physiol 278, G834-838.
15. + currents in adult rat sensory neurons. J Neurophysiol 75, 2629-2646.
16. Gold MS, Zhang L, Wrigley DL & Traub RJ (2002). Prostaglandin E(2) modulates TTX-RI(Na). in rat colonic sensory neurons. J Neurophysiol 88, 1512-1522.
17. Gould HJ III, England JD, Liu ZP & Levinson SR (1998). Rapid sodium channel augmentation in response to inflammation induced by complete Freund's adjuvant. Brain Res 802, 69-74.
18. Gould HJ III, Gould TN, Paul D, England JD, Liu ZP, Reeb SC & Levinson SR (1999). Development of inflammatory hypersensitivity and augmentation of sodium channels in rat dorsal root ganglia. Brain Res 824, 296-299.
19. Hamill OP, Marty A, Neher E, Sakmann B & Sigworth FJ (1981). Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391, 85-100.
20. Hille B (1992). In Ion Channels of Excitable Membranes. Sinauer Associates, Sunderland, MA, USA.
21. Khasar SG, Gold MS & Levine JD (1998). A tetrodotoxin-resistant sodium current mediates inflammatory pain in the rat. Neurosci Lett 256, 17-20.
22. Laird JM, Souslova V, Wood JN & Cervero F (2002). Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice. J Neurosci 22, 8352-8356.
23. McCleskey EW & Gold MS (1999). Ion channels of nociception. Annu Rev Physiol 61, 835-856.
24. McFarlane S & Cooper E (1991). Kinetics and voltage dependence of A-type currents on neonatal rat sensory neurons. J Neurophysiol 66, 1380-1391.
25. Mayer EA & Gebhart GF (1994). Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 107, 271-293.
26. Moore BA, Stewart TM, Hill C & Vanner SJ (2002). TNBS ileitis evokes hyperexcitability and changes in ionic membrane properties of nociceptive DRG neurons. Am J Physiol Gastrointest Liver Physiol 282, G1045-1051.
27. Nicol GD, Vasko MR & Evans AR (1997). Prostaglandins suppress an outward potassium current in embryonic rat sensory neurons. J Neurophysiol 77, 167-176.
28. Philipson LH, Hice RE, Schaefer K, Lamendola J, Bell GI, Nelson DJ & Steiner DF (1991). Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel. Proc Natl Acad Sci U S A 88, 53-57.
29. Rang HP, Bevan S & Dray A (1991). Chemical activation of nociceptive peripheral neurones. Br Med Bull 47, 534-548.
30. + channel (Kv1.4). cloned from ferret ventricle and expressed in Xenopus oocytes. J Physiol 485, 59-71.
31. Renganathan M, Cummins TR & Waxman SG (2001). Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons. J Neurophysiol 86, 629-640.
32. Rudy B (1988). Diversity and ubiquity of K channels. Neuroscience 25, 729-749.
33. Sengupta JN & Gebhart GF (1994). Characterization of mechanosensitive pelvic nerve afferent fibers innervating the colon of the rat. J Neurophysiol 71, 2046-2060.
34. + channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model. Neuroreport 9, 967-972.
35. Thompson S (1982). Aminopyridine block of transient potassium current. J Gen Physiol 80, 1-18.
36. Tornblom H, Lindberg G, Nyberg B & Veress B (2002). Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome. Gastroenterology 123, 1972-1979.
37. Woolf CJ & Costigan M (1999). Transcriptional and posttranslational plasticity and the generation of inflammatory pain. Proc Natl Acad Sci U S A 96, 7723-7730.
38. Yang F, Feng L, Zheng F, Johnson SW, Du J, Shen L, Wu CP & Lu B (2001). GDNF acutely modulates excitability and A-type K(+). channels in midbrain dopaminergic neurons. Nat Neurosci 4, 1071-1078.
39. Yoshimura N & de Groat WC (1999). Increased excitability of afferent neurons innervating rat urinary bladder after chronic bladder inflammation. J Neurosci 19, 4644-4653.
40. Yoshimura N, Seki S, Novakovic SD, Tzoumaka E, Erickson VL, Erickson KA, Chancellor MB & De Groat WC (2001). The involvement of the tetrodotoxin-resistant sodium channel Na(v)1.8 (PN3/SNS) in a rat model of visceral pain. J Neurosci 21, 8690-8696.
41. + currents in dorsal root ganglion neurones innervating the rat urinary bladder. J Physiol 494, 1-16.
42. Zhang YH, Vasko MR & Nicol GD (2002). Ceramide, a putative second messenger for nerve growth factor, modulates the TTX-resistant Na(+) current and delayed rectifier K(+) current in rat sensory neurons. J Physiol 544, 385-402.