A natural diarylheptanoid promotes neuronal differentiation via activating ERK and PI3K-Akt dependent pathways

Neuroscience

Volumn 303, Issue , 2015, Pages 389-401

  Tang, G ^a   Dong, X ^a   Huang, X ^a   Huang, X J ^a   Liu, H ^a   Wang, Y ^a   Ye, W C ^a   Shi, L ^a  

^a JINAN UNIVERSITY   (China)

Author keywords

Adult neurogenesis; Dentate gyrus; Natural product; Neurite outgrowth; Neuronal differentiation; Neuronal polarization

Indexed keywords

1,7 DIPHENYL 5 HYDROXY 3 HEPTANONE; 5 ETHOXY 7 (4 HYDROXY 3 METHOXYPHENYL) 1 PHENYL 3 HEPTANONE; 5 HYDROXY 1,7 DIPHENYL 4,6 HEPTADIENE 3 ONE; 5 HYDROXY 1,7 DIPHENYL 6 HEPTEN 3 ONE; 5 HYDROXY 7 (3,4 DIHYDROXYPHENYL) 1 PHENYL 3 HEPTANONE; 5 HYDROXY 7 (4 HYDROXY 3 METHOXYPHENYL) 1 PHENYL 3 HEPTANONE; 5 HYDROXY 7 (4 HYDROXYPHENYL) 1 PHENYL 3 HEPTANONE; 7 (4 HYDROXY 3 METHOXYPHENYL) 1 PHENYL 4 HEPTEN 3 ONE; 7 (4 HYDROXYPHENYL) 1 PHENYL 4 HEPTEN 3 ONE; CURCUMIN; HEPTANE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PROTEIN KINASE B; RETINOIC ACID; UNCLASSIFIED DRUG; CASPASE 3; ENZYME INHIBITOR; NERVE PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL POLARITY; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; EMBRYO; ENZYME ACTIVATION; HIPPOCAMPAL NEURONAL CULTURE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FIBER; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NEUROBLASTOMA CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RHIZOME; SIGNAL TRANSDUCTION; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; HIPPOCAMPUS; MAMMALIAN EMBRYO; METABOLISM; NERVE CELL; NEURITE; NEUROBLASTOMA; PATHOLOGY; PHYSIOLOGY; TIME FACTOR;

ANIMALS; APOPTOSIS; CASPASE 3; CELL DIFFERENTIATION; CELLS, CULTURED; DIARYLHEPTANOIDS; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURITES; NEUROBLASTOMA; NEURONS; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; SIGNAL TRANSDUCTION; TIME FACTORS; TRETINOIN;

EID: 84937393332     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.07.019     Document Type: Article

References (50)

1. Ahmed T., Gilani A.H. Therapeutic potential of turmeric in Alzheimer's disease: curcumin or curcuminoids?. Phytother Res 2014, 28:517-525.
2. Biernat J., Wu Y.Z., Timm T., Zheng-Fischhofer Q., Mandelkow E., Meijer L., Mandelkow E.M Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity. Mol Biol Cell 2002, 13:4013-4028.
3. Chen F., Wang H., Xiang X., Yuan J., Chu W., Xue X., Zhu H., Ge H., Zou M., Feng H., Lin J. Curcumin increased the differentiation rate of neurons in neural stem cells via wnt signaling in vitro study. J Surg Res 2014, pii: S0022-4804(14)00576-9. 10.1016/j.jss.2014.06.026.2014.
4. da Silva J.S., Dotti C.G. Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis. Nat Rev 2002, 3:694-704.
5. Darvesh A.S., Carroll R.T., Bishayee A., Novotny N.A., Geldenhuys W.J., Van der Schyf C.J. Curcumin and neurodegenerative diseases: a perspective. Expert Opin Investig Drugs 2012, 21:1123-1140.
6. Dong S., Zeng Q., Mitchell E.S., Xiu J., Duan Y., Li C., Tiwari J.K., Hu Y., Cao X., Zhao Z. Curcumin enhances neurogenesis and cognition in aged rats: implications for transcriptional interactions related to growth and synaptic plasticity. PLoS ONE 2012, 7:e31211.
7. Drew L.J., Fusi S., Hen R. Adult neurogenesis in the mammalian hippocampus: why the dentate gyrus?. Learn Memory (Cold Spring Harbor, NY) 2013, 20:710-729.
8. Duan X., Kang E., Liu C.Y., Ming G.L., Song H. Development of neural stem cell in the adult brain. Curr Opin Neurobiol 2008, 18:108-115.
9. Gaspard N., Vanderhaeghen P. Mechanisms of neural specification from embryonic stem cells. Curr Opin Neurobiol 2010, 20:37-43.
10. Hamaguchi T., Ono K., Yamada M. REVIEW: Curcumin and Alzheimer's disease. CNS Neurosci Ther 2010, 16:285-297.
11. Hansen T.O., Rehfeld J.F., Nielsen F.C. Cyclic AMP-induced neuronal differentiation via activation of p38 mitogen-activated protein kinase. J Neurochem 2000, 75:1870-1877.
12. Ip J.P., Shi L., Chen Y., Itoh Y., Fu W.Y., Betz A., Yung W.H., Gotoh Y., Fu A.K., Ip N.Y. Alpha2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2. Nat Neurosci 2012, 15:39-47.
13. Jun H., Mohammed Qasim Hussaini S., Rigby M.J., Jang M.H. Functional role of adult hippocampal neurogenesis as a therapeutic strategy for mental disorders. Neural Plast 2012, 2012:854285.
14. Kim H.J., Jin C.Y. Stem cells in drug screening for neurodegenerative disease. Korean J Physiol Pharmacol 2012, 16:1-9.
15. Kim S.J., Son T.G., Park H.R., Park M., Kim M.S., Kim H.S., Chung H.Y., Mattson M.P., Lee J. Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. J Biol Chem 2008, 283:14497-14505.
16. Konno K., Miura M., Toriyama M., Motohashi S., Sawamura R., Watanabe W., Yoshida H., Kato M., Yamamoto R., Yasukawa K., Kurokawa M. Antiviral activity of diarylheptanoid stereoisomers against respiratory syncytial virus in vitro and in vivo. J Nat Med 2013, 67:773-781.
17. Li Z., Theus M.H., Wei L. Role of ERK 1/2 signaling in neuronal differentiation of cultured embryonic stem cells. Dev Growth Differ 2006, 48:513-523.
18. Liao K.K., Wu M.J., Chen P.Y., Huang S.W., Chiu S.J., Ho C.T., Yen J.H. Curcuminoids promote neurite outgrowth in PC12 cells through MAPK/ERK- and PKC-dependent pathways. J Agric Food Chem 2012, 60:433-443.
19. Lu Z., Shen Y., Wang T., Cui M., Wang Z., Zhao H., Dong Q. Curcumin promotes neurite outgrowth via reggie-1/flotillin-2 in cortical neurons. Neurosci Lett 2014, 559:7-12.
20. Matsuda H., Nakashima S., Oda Y., Nakamura S., Yoshikawa M. Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cells. Bioorg Med Chem 2009, 17:6048-6053.
21. Ming G.L., Song H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 2011, 70:687-702.
22. Monroy A., Lithgow G.J., Alavez S. Curcumin and neurodegenerative diseases. BioFactors (Oxford, England) 2013, 39:122-132.
23. More S.V., Koppula S., Kim I.S., Kumar H., Kim B.W., Choi D.K. The role of bioactive compounds on the promotion of neurite outgrowth. Molecules (Basel, Switzerland) 2012, 17:6728-6753.
24. Nam S.M., Choi J.H., Yoo D.Y., Kim W., Jung H.Y., Kim J.W., Yoo M., Lee S., Kim C.J., Yoon Y.S., Hwang I.K. Effects of curcumin (Curcuma longa) on learning and spatial memory as well as cell proliferation and neuroblast differentiation in adult and aged mice by upregulating brain-derived neurotrophic factor and CREB signaling. J Med Food 2014, 17:641-649.
25. Peltier J., O'Neill A., Schaffer D.V. PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation. Dev Neurobiol 2007, 67:1348-1361.
26. Perron J.C., Bixby J.L. Distinct neurite outgrowth signaling pathways converge on ERK activation. Mol Cell Neurosci 1999, 13:362-378.
27. Polleux F., Snider W. Initiating and growing an axon. Cold Spring Harbor Perspect Biol 2010, 2:a001925.
28. Radio N.M. Neurite outgrowth assessment using high content analysis methodology. Methods Mol Biol (Clifton, NJ) 2012, 846:247-260.
29. Read D.E., Gorman A.M. Involvement of Akt in neurite outgrowth. Cell Mol Life Sci 2009, 66:2975-2984.
30. Sailor K.A., Ming G.L., Song H. Neurogenesis as a potential therapeutic strategy for neurodegenerative diseases. Exp Opin Biol Ther 2006, 6:879-890.
31. Samuels I.S., Saitta S.C., Landreth G.E. MAP'ing CNS development and cognition: an ERKsome process. Neuron 2009, 61:160-167.
32. Sanchez S., Jimenez C., Carrera A.C., Diaz-Nido J., Avila J., Wandosell F. A cAMP-activated pathway, including PKA and PI3K, regulates neuronal differentiation. Neurochem Int 2004, 44:231-242.
33. Schoenfeld T.J., Cameron H.A. Adult Neurogenesis and Mental Illness. Neuropsychopharmacology 2014, 10.1038/npp.2014.230.2014.
34. Shea T.B., Fischer I., Sapirstein V.S. Effect of retinoic acid on growth and morphological differentiation of mouse NB2a neuroblastoma cells in culture. Brain Res. 1985, 353:307-314.
35. Shi L., Fu W.Y., Hung K.W., Porchetta C., Hall C., Fu A.K., Ip N.Y. Alpha2-chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse. Proc Natl Acad Sci U S A 2007, 104:16347-16352.
36. Su J., Sripanidkulchai K., Suksamrarn A., Hu Y., Piyachuturawat P., Sripanidkulchai B. Pharmacokinetics and organ distribution of diarylheptanoid phytoestrogens from Curcuma comosa in rats. J Nat Med 2012, 66:468-475.
37. Tabata K., Yamazaki Y., Okada M., Fukumura K., Shimada A., Sun Y., Yasukawa K., Suzuki T. Diarylheptanoids derived from Alpinia officinarum induce apoptosis, S-phase arrest and differentiation in human neuroblastoma cells. Anticancer Res. 2009, 29:4981-4988.
38. Tahirovic S., Bradke F. Neuronal polarity. Cold Spring Harbor Perspect Biol 2009, 1:a001644.
39. Tantikanlayaporn D., Robinson L.J., Suksamrarn A., Piyachaturawat P., Blair H.C. A diarylheptanoid phytoestrogen from Curcuma comosa, 1,7-diphenyl-4,6-heptadien-3-ol, accelerates human osteoblast proliferation and differentiation. Phytomedicine 2013, 20:676-682.
40. Tian Z., An N., Zhou B., Xiao P., Kohane I.S., Wu E. Cytotoxic diarylheptanoid induces cell cycle arrest and apoptosis via increasing ATF3 and stabilizing p53 in SH-SY5Y cells. Cancer Chemother Pharmacol 2009, 63:1131-1139.
41. Tiwari S.K., Agarwal S., Seth B., Yadav A., Nair S., Bhatnagar P., Karmakar M., Kumari M., Chauhan L.K., Patel D.K., Srivastava V., Singh D., Gupta S.K., Tripathi A., Chaturvedi R.K., Gupta K.C. Curcumin-loaded nanoparticles potently induce adult neurogenesis and reverse cognitive deficits in Alzheimer's disease model via canonical Wnt/beta-catenin pathway. ACS Nano 2014, 8:76-103.
42. Tsai Y.M., Chien C.F., Lin L.C., Tsai T.H. Curcumin and its nano-formulation: the kinetics of tissue distribution and blood-brain barrier penetration. Int J Pharm 2011, 416:331-338.
43. Xiao Y., Peng Y., Wan J., Tang G., Chen Y., Tang J., Ye W.C., Ip N.Y., Shi L. The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics. J Biol Chem 2013, 288:20034-20045.
44. Xu Y., Ku B., Cui L., Li X., Barish P.A., Foster T.C., Ogle W.O. Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats. Brain Res. 2007, 1162:9-18.
45. Xu S.L., Zhu K.Y., Bi C.W., Yan L., Men S.W., Dong T.T., Tsim K.W. Flavonoids, derived from traditional Chinese medicines, show roles in the differentiation of neurons: possible targets in developing health food products. Birth Defects Res C Embryo Today 2013, 99:292-299.
46. Xu J., Lacoske M.H., Theodorakis E.A. Neurotrophic natural products: chemistry and biology. Angew Chem, Int Ed 2014, 53:956-987.
47. Yadav P.N., Liu Z., Rafi M.M. A diarylheptanoid from lesser galangal (Alpinia officinarum) inhibits proinflammatory mediators via inhibition of mitogen-activated protein kinase, p44/42, and transcription factor nuclear factor-kappa B. J Pharmacol Exp Ther 2003, 305:925-931.
48. Yanes O., Clark J., Wong D.M., Patti G.J., Sanchez-Ruiz A., Benton H.P., Trauger S.A., Desponts C., Ding S., Siuzdak G. Metabolic oxidation regulates embryonic stem cell differentiation. Nat Chem Biol 2010, 6:411-417.
49. Yoshimura T., Arimura N., Kaibuchi K. Signaling networks in neuronal polarization. J Neurosci 2006, 26:10626-10630.
50. Zhang J., Shemezis J.R., McQuinn E.R., Wang J., Sverdlov M., Chenn A. AKT activation by N-cadherin regulates beta-catenin signaling and neuronal differentiation during cortical development. Neural Dev 2013, 8:7.