A diarylheptanoid phytoestrogen from Curcuma comosa, 1,7-diphenyl-4,6- heptadien-3-ol, accelerates human osteoblast proliferation and differentiation

Phytomedicine

Volumn 20, Issue 8-9, 2013, Pages 676-682

  Tantikanlayaporn, Duangrat ^a,b   Robinson, Lisa J ^b   Suksamrarn, Apichart ^c   Piyachaturawat, Pawinee ^a   Blair, Harry C ^b,d  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c RAMKHAMHAENG UNIVERSITY   (Thailand)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Curcuma comosa; Diarylheptanoid; ERK1 2; Osteoporosis; Phytoestrogen; Selective estrogen receptor modulator

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; COLLAGEN TYPE 1A1; DIARYLHEPTANOID 1,7 DIPHENYL 4,6 HEPTADIEN 3 OL; ESTRADIOL; FULVESTRANT; HEPTANE DERIVATIVE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCALCIN; PHYTOESTROGEN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CURCUMA; CURCUMA COMOSA; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RHIZOME; SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; CELL PROLIFERATION; CURCUMA; DIARYLHEPTANOIDS; ESTRADIOL; FEMALE; HEPTANOL; HUMANS; MAP KINASE SIGNALING SYSTEM; MENOPAUSE; OSTEOBLASTS; OSTEOCALCIN; OSTEOPOROSIS; OSTEOPROTEGERIN; PHYTOESTROGENS; PLANT EXTRACTS; RANK LIGAND; RHIZOME; RNA, MESSENGER;

CURCUMA COMOSA; MUS; ZINGIBERACEAE;

EID: 84878107961     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.02.008     Document Type: Article

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