Pharmacokinetics and organ distribution of diarylheptanoid phytoestrogens from Curcuma comosa in rats

Journal of Natural Medicines

Volumn 66, Issue 3, 2012, Pages 468-475

  Su, Jian ^a   Sripanidkulchai, Kittisak ^b   Suksamrarn, Apichart ^c   Hu, Ying ^a   Piyachuturawat, Pawinee ^d   Sripanidkulchai, Bungorn ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

^c RAMKHAMHAENG UNIVERSITY   (Thailand)

^d Mahidol University   (Thailand)

Author keywords

Bioavailability; Curcuma comosa; Diarylheptanoids; HPLC; Organ distribution; Pharmacokinetics; Phytoestrogen

Indexed keywords

1,7 DIPHENYLHEPT 6 EN 3 OL; 1,7 DIPHENYLHEPT 6 EN 3 ONE; 1,7 DIPHENYLHEPTA 4,6 DIEN 3 OL; CURCUMA COMOSA EXTRACT; HEPTANE DERIVATIVE; PHYTOESTROGEN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BRAIN; CONTROLLED STUDY; CURCUMA; CURCUMA COMOSA; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG HALF LIFE; DRUG STRUCTURE; DRUG TISSUE LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY; LIVER; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; OVARY; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; TISSUE DISTRIBUTION; UTERUS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CURCUMA; DIARYLHEPTANOIDS; FEMALE; PHYTOESTROGENS; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 84863528007     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-011-0607-x     Document Type: Article

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