In vivo analysis of Nef's role in HIV-1 replication, systemic T cell activation and CD4+ T cell loss

Retrovirology

Volumn 12, Issue 1, 2015, Pages

  Watkins, Richard L ^a   Foster, John L ^a   Garcia, J Victor ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

HIV 1; Nef; Pathogenesis; Replication

Indexed keywords

CD34 ANTIGEN; CD38 ANTIGEN; CD8 ANTIGEN; HLA B ANTIGEN; HLA DR ANTIGEN; NEF PROTEIN; VIRUS RNA; NEF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CD4+ T LYMPHOCYTE; CELL LOSS; CONTROLLED STUDY; HLA SYSTEM; HOST RANGE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VIVO STUDY; LIVER; LUNG; LYMPH NODE; MOUSE; NONHUMAN; PROTEIN FUNCTION; SPLEEN; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; THYMOCYTE; VIREMIA; VIRUS LOAD; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; ANIMAL STRUCTURES; BLOOD; CD8+ T LYMPHOCYTE; HOST PATHOGEN INTERACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; SCID MOUSE; VIROLOGY;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

ANIMAL STRUCTURES; ANIMALS; BLOOD; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MICE, SCID; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; VIRUS REPLICATION;

EID: 84937027818     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/s12977-015-0187-z     Document Type: Article

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