CXCR4 tropic human immunodeficiency virus type 1 induces an apoptotic cascade in immature infected thymocytes that resembles thymocyte negative selection

Virology

Volumn 352, Issue 2, 2006, Pages 268-284

  Choudhary, Shailesh K ^a   Walker, Russell M ^b   Powell, Douglas M ^b   Planelles, Vicente ^c   Walsh, Craig ^d   Camerini, David ^a  

^a Center for Immunology   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; HIV 1; Negative selection; Thymocyte

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; CHEMOKINE RECEPTOR CXCR4; CYCLOHEXIMIDE; DNA TOPOISOMERASE INHIBITOR; EFAVIRENZ; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR;

APOPTOSIS; ARTICLE; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL SELECTION; CONTROLLED STUDY; ENZYME ACTIVATION; FETUS; GENE INDUCTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; STATISTICAL SIGNIFICANCE; THYMOCYTE; VIRUS INFECTION;

ANTIGENS, CD4; ANTIGENS, CD8; APOPTOSIS; CASPASES; CELL DIFFERENTIATION; CYCLOSPORINE; FLAVONOIDS; GENE EXPRESSION; HIV INFECTIONS; HIV-1; HUMANS; PROTEIN BIOSYNTHESIS; RECEPTORS, CXCR4; T-LYMPHOCYTES; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 33747082338     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.04.037     Document Type: Article

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