Manganese-enhanced MRI of the rat visual pathway: Acute neural toxicity, contrast enhancement, axon resolution, axonal transport, and clearance of Mn2+

Journal of Magnetic Resonance Imaging

Volumn 28, Issue 4, 2008, Pages 855-865

  Thuen, Marte ^a,d   Berry, Martin ^b   Pedersen, Tina Bugge ^a   Goa, Pål Erik ^a,c   Summerfield, Mike ^b   Haraldseth, Olav ^a,c   Sandvig, Axel ^a   Brekken, Christian ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^d Medical Technical Research Center Trondheim   (Norway)

Author keywords

Manganese; MEMRI; MRI; Toxicity; Transport; Visual pathway

Indexed keywords

FLUOROGOLD; MANGANESE CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTRAST ENHANCEMENT; CONTRAST TO NOISE RATIO; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; FEMALE; FISCHER 344 RAT; NERVE FIBER TRANSPORT; NEUROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL RESOLUTION; OPTIMAL DRUG DOSE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; SINGLE DRUG DOSE; SPRAGUE DAWLEY RAT; VISUAL SYSTEM;

ANIMALS; AXONS; CHLORIDES; CONTRAST MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE IMAGING; MANGANESE COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; RETINA; VISUAL PATHWAYS;

EID: 53549113613     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.21504     Document Type: Article

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