Structural and sequencing analysis of local target DNA recognition by MLV integrase

Nucleic Acids Research

Volumn 43, Issue 11, 2015, Pages 5647-5663

  Aiyer, Sriram ^a   Rossi, Paolo ^b,f   Malani, Nirav ^c   Schneider, William M ^a,d   Chandar, Ashwin ^a,e   Bushman, Frederic D ^c   Montelione, Gaetano T ^a,b   Roth, Monica J ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b The State University of New Jersey   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e ROBERT WOOD JOHNSON UNIVERSITY HOSPITAL   (United States)

^f Rutgers SAS Chemistry and Chemical Biology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; PROTEIN SH3; DNA; PROTEIN BINDING; VIRUS PROTEIN;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYTIC CORE DOMAIN; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA BINDING; IN VIVO STUDY; MOLECULAR MODEL; MOLONEY MURINE LEUKEMIA VIRUS; NEXT GENERATION SEQUENCING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN MOTIF; STRUCTURE ANALYSIS; TISSUE CULTURE; VIRUS EXAMINATION; VIRUS MORPHOLOGY; VIRUS MUTANT; VIRUS REPLICATION; CHEMICAL STRUCTURE; CHEMISTRY; DNA SEQUENCE; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; METABOLISM; MUTATION; PROTEIN TERTIARY STRUCTURE;

HUMAN SPUMARETROVIRUS; MOLONEY MURINE LEUKEMIA VIRUS;

CATALYTIC DOMAIN; DNA; INTEGRASES; MODELS, MOLECULAR; MOLONEY MURINE LEUKEMIA VIRUS; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, DNA; VIRAL PROTEINS;

EID: 84936852971     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv410     Document Type: Article

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