HIV-1 integrase variants retarget viral integration and are associated with disease progression in a chronic infection cohort

Cell Host and Microbe

Volumn 16, Issue 5, 2014, Pages 651-662

  Demeulemeester, Jonas ^a,b   Vets, Sofie ^a   Schrijvers, Rik ^a   Madlala, Paradise ^a,c   De Maeyer, Marc ^b   De Rijck, Jan ^a   Ndung'U, Thumbi ^c,d,e,f   Debyser, Zeger ^a   Gijsbers, Rik ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

^d UNIVERSITY OF KWAZULU NATAL   (South Africa)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^f MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; DNA BASE; INTEGRASE; TETRAMER; VIRUS ENZYME; P31 INTEGRASE PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; RECOMBINANT PROTEIN; VIRUS DNA;

ALLELE; AMINO ACID SUBSTITUTION; ANTIVIRAL THERAPY; ARTICLE; CATALYSIS; CHROMATIN; CHRONIC DISEASE; DISEASE COURSE; DNA SEQUENCE; GENE INSERTION; GENETIC VARIABILITY; HELA CELL LINE; HLA SYSTEM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN POLYMORPHISM; RETROVIRUS; VIRUS DNA CELL DNA INTERACTION; VIRUS GENOME; VIRUS INFECTION; VIRUS REPLICATION; VIRUS VIRULENCE; AMINO ACID SEQUENCE; BIOLOGY; ENZYMOLOGY; GENETIC POLYMORPHISM; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN CONFORMATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; CLONING, MOLECULAR; COMPUTATIONAL BIOLOGY; DISEASE PROGRESSION; DNA, VIRAL; GENOME, VIRAL; HELA CELLS; HIV INFECTIONS; HIV INTEGRASE; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; VIRUS INTEGRATION; VIRUS REPLICATION;

EID: 84910597493     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2014.09.016     Document Type: Article

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