Current basis for discovery and development of aryl hydrocarbon receptor antagonists for experimental and therapeutic use in atherosclerosis

European Journal of Pharmacology

Volumn 764, Issue , 2015, Pages 118-123

  Pernomian, Larissa ^a   Da Silva, Carlos H T P ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aryl hydrocarbon receptor antagonists; Atherosclerosis; Cigarette smoke; Drug design; Molecular modeling

Indexed keywords

1 METHYL N [2 METHYL 4 [2 (2 METHYLPHENYL)DIAZENYL]PHENYL] 1H PYRAZOLE 5 CARBOXAMIDE; 3' METHOXY 4' NITROFLAVONE; 6,2',4' TRIMETHOXYFLAVONE; ALPHA NAPHTHOFLAVONE; AROMATIC HYDROCARBON RECEPTOR; AROMATIC HYDROCARBON RECEPTOR ANTAGONIST; CARDIOVASCULAR AGENT; ESTROGEN RECEPTOR; KAEMPFEROL; RESVERATROL; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; BINDING AFFINITY; BINDING SITE; CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; HEART PROTECTION; HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG DEVELOPMENT; METABOLISM; PROCEDURES;

ANIMALS; ATHEROSCLEROSIS; DRUG DISCOVERY; HUMANS; RECEPTORS, ARYL HYDROCARBON;

EID: 84936803810     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.06.058     Document Type: Review

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