The golgi-localized γ-ear-containing ARF-binding (GGA) proteins alter amyloid-β precursor protein (APP) processing through interaction of their GAE domain with the beta-site APP cleaving enzyme 1 (BACE1)

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Von Einem, Bjoern ^a   Wahler, Anke ^a   Schips, Tobias ^a   Serrano Pozo, Alberto ^b   Proepper, Christian ^a   Boeckers, Tobias M ^a   Rueck, Angelika ^a   Wirth, Thomas ^a   Hyman, Bradley T ^b   Danzer, Karin M ^a   Thal, Dietmar R ^a   Von Arnim, Christine A F ^a  

^a UNIVERSITY OF ULM   (Germany)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; GGA ADAPTOR PROTEINS; PROTEIN BINDING; SECRETASE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL; BRAIN; CELL LINE; CHEMISTRY; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; MOUSE; MULTIGENE FAMILY; PROTEIN DEGRADATION; PROTEIN DOMAIN;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CELL LINE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MULTIGENE FAMILY; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEOLYSIS; SEQUENCE DELETION;

EID: 84936792259     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0129047     Document Type: Article

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