Do gga adaptors bind internal dxxll motifs?

Traffic

Volumn 13, Issue 10, 2012, Pages 1315-1325

  Doray, Balraj ^a   Misra, Saurav ^b   Qian, Yi ^a   Brett, Tom J ^a   Kornfeld, Stuart ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

DXXLL motifs; GGA cargo molecules; GGA proteins

Indexed keywords

ADAPTOR PROTEIN; CLATHRIN; MUTANT PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOPLASM; MOLECULAR MODEL; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; SEQUENCE ALIGNMENT; WILD TYPE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMINO ACID MOTIFS; ANIMALS; HEK293 CELLS; HUMANS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-1; MICE; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; TRANS-GOLGI NETWORK;

EID: 84866280614     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2012.01396.x     Document Type: Article

References (31)

1. Bonifacino JS, The GGA proteins: adaptors on the move. Nat Rev Mol Cell Biol 2004;5:23-32.
2. Braulke T, Bonifacino JS. Sorting of lysosomal proteins. Biochim Biophys Acta 2009;1793:605-614.
3. Puertollano R, Randazzo PA, Presley JF, Hartnell LM, Bonifacino JS. The GGAs promote ARF-dependent recruitment of clathrin to the TGN. Cell 2001;105:93-102.
4. Zhu Y, Doray B, Poussu A, Lehto VP, Kornfeld S. Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor. Science 2001;292:1716-1718.
5. Bonifacino JS, Traub LM. Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu Rev Biochem 2003;72:395-447.
6. Doray B, Bruns K, Ghosh P, Kornfeld S. Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif. Proc Natl Acad Sci USA 2002;99:8072-8077.
7. Kzhyshkowska J, Gratchev A, Martens JH, Pervushina O, Mamidi S, Johansson S, Schledzewski K, Hansen B, He X, Tang J, Nakayama K, Goerdt S. Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors. J Leukoc Biol 2004;76:1151-1161.
8. Boucher R, Larkin H, Brodeur J, Gagnon H, Thériault C, Lavoie C. Intracellular trafficking of LRP9 is dependent on two acidic cluster/dileucine motifs. Histochem Cell Biol 2008;130:315-327.
9. Doray B, Knisely JM, Wartman L, Bu G, Kornfeld S. Identification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2. Traffic 2008;9:1551-1562.
10. Zhang J, Gratchev A, Riabov V, Mamidi S, Schmuttermaier C, Krusell L, Kremmer E, Workman G, Sage EH, Jalkanen S, Goerdt S, Kzhyshkowska J. A novel GGA-binding site is required for intracellular sorting mediated by stabilin-1. Mol Cell Biol 2009;29:6097-105.
11. del Castillo FJ, Cohen-Salmon M, Charollais A, Caille D, Lampe PD, Chavrier P, Meda P, Petit C. Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins. Hum Mol Genet 2010;19:262-275.
12. Stauber T, Jentsch TJ. Sorting motifs of the endosomal/lysosomal CLC chloride transporters. J Biol Chem 2010;285:34537-34548.
13. Cramer JF, Gustafsen C, Behrens MA, Oliveira CL, Pedersen JS, Madsen P, Petersen CM, Thirup SS. GGA autoinhibition revisited. Traffic 2010;11:259-73.
14. Misra S, Puertollano R, Kato Y, Bonifacino JS, Hurley JH. Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature 2002;415:933-937.
15. Shiba T, Kametaka S, Kawasaki M, Shibata M, Waguri S, Uchiyama Y, Wakatsuki S. Insights into the phosphoregulation of beta-secretase sorting signal by the VHS domain of GGA1. Traffic 2004;5:437-448.
16. Shiba T, Takatsu H, Nogi T, Matsugaki N, Kawasaki M, Igarashi N, Suzuki M, Kato R, Earnest T, Nakayama K, Wakatsuki S. Structural basis for recognition of acidic-cluster dileucine sequence by GGA1. Nature 2002;415:937-941.
17. Zhu G, He X, Zhai P, Terzyan S, Tang J, Zhang XC. Crystal structure of GGA2 VHS domain and its implication in plasticity in the ligand binding pocket. FEBS Lett 2003;537:171-176.
18. Raveh B, London N, Schueler-Furman O. Sub-angstrom modeling of complexes between flexible peptides and globular proteins. Proteins 2010;78:2029-2040.
19. London N, Raveh B, Cohen E, Fathi G, Schueler-Furman O. Rosetta FlexPepDock web server-high resolution modeling of peptide-protein interactions. Nucleic Acids Res 2011;39: W249-W253.
20. Puertollano R, Aguilar RC, Gorshkova I, Crouch RJ, Bonifacino JS. Sorting of mannose 6-phosphate receptors mediated by the GGAs. Science 2001;292:1712-1716.
21. Kato Y, Misra S, Puertollano R, Hurley JH, Bonifacino JS. Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism. Nat Struct Biol 2002;9:532-536.
22. Inoue M, Shiba T, Ihara K, Yamada Y, Hirano S, Kamikubo H, Kataoka M, Kawasaki M, Kato R, Nakayama K, Wakatsuki S. Molecular basis for autoregulatory interaction between GAE domain and hinge region of GGA1. Traffic 2007;8:904-913.
23. Bai H, Doray B, Kornfeld S. GGA1 interacts with the adaptor protein AP-1 through a WNSF sequence in its hinge region. J Biol Chem 2004;279:17411-17417.
24. Hirst J, Carmichael J. A potential role for the clathrin adaptor GGA in Drosophila spermatogenesis. BMC Cell Biol 2011;12:22.
25. Dennes A, Cromme C, Suresh K, Kumar NS, Eble JA, Hahnenkamp A, Pohlmann R. The novel Drosophila lysosomal enzyme receptor protein mediates lysosomal sorting in mammalian cells and binds mammalian and Drosophila GGA adaptors. J Biol Chem 2005;280:12849-12857.
26. von Arnim CA, Tangredi MM, Peltan ID, Lee BM, Irizarry MC, Kinoshita A, Hyman BT. Demonstration of BACE (beta-secretase) phosphorylation and its interaction with GGA1 in cells by fluorescence-lifetime imaging microscopy. J Cell Sci 2004;117:5437-5445.
27. Hermey G, Keat SJ, Madsen P, Jacobsen C, Petersen CM, Gliemann J. Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells. J Biol Chem 2003;278:7390-7396.
28. Doray B, Bruns K, Ghosh P, Kornfeld S. Interaction of the cation-dependent mannose 6-phosphate receptor with GGA proteins. J Biol Chem 2002;277:18477-18482.
29. van Valen D, Haataja M, Phillips R. Biochemistry on a leash: the roles of tether length and geometry in signal integration proteins. Biophys J 2009;96:1275-1292.
30. Emsley P, Lohkamp B, Scott WG, Cowtan K. Features and development of Coot. Acta Crystallogr D Biol Crystallogr 2010;66:486-501.
31. DeLano WL. The PyMOL molecular graphics system, 2002. http://pymol.sourceforge.net.