Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting

FEBS Journal

Volumn 281, Issue 8, 2014, Pages 2074-2087

  John, Bincy A ^a   Meister, Melanie ^a   Banning, Antje ^a   Tikkanen, Ritva ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Alzheimer's disease; endocytic cargo; endocytosis; endosomal sorting; secretase

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; FLOTILLIN 1; FLOTILLIN 2;

ARTICLE; BINDING COMPETITION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DILEUCINE SORTING MOTIF; ENDOSOME; HELA CELL; HUMAN; HUMAN CELL; MEMBRANE TRANSPORT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING;

ALZHEIMER'S DISEASE; ENDOCYTIC CARGO; ENDOCYTOSIS; ENDOSOMAL SORTING; Β-SECRETASE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ACID ENDOPEPTIDASES; ENDOSOMES; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; PROTEIN BINDING; PROTEIN TRANSPORT;

EID: 84899411384     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12763     Document Type: Article

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