Functional genomic screen identifies klebsiella pneumoniae factors implicated in blocking nuclear factor κB (NF-κB) signaling

Journal of Biological Chemistry

Volumn 290, Issue 27, 2015, Pages 16678-16697

  Tomás, Anna ^a,b,c   Lery, Leticia ^d,e   Regueiro, Verónica ^a,b,c   Pérez Gutiérrez, Camino ^a,b,c   Martínez, Verónica ^a,b,c   Moranta, David ^a,b,c   Llobet, Enrique ^a,b,c   González Nicolau, Mar ^a,b,c   Insua, Jose L ^f   Tomas, Juan M ^g   Sansonetti, Philippe J ^d,e,h   Tournebize, Régis ^d,e   Bengoechea, José A ^f,i  

^a Infection and Immunity Program Fundación de Investigación Sanitaria de Las Islas Baleares FISIB   (Spain)

^b HEALTH RESEARCH INSTITUTE OF THE BALEARIC ISLANDS IDISBA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d INSTITUT PASTEUR   (France)

^e INSERM   (France)

^f QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^g UNIVERSITY OF BARCELONA   (Spain)

^h l'alimentation et l'Environnement   (France)

ⁱ CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

FUNCTIONAL GENOMICS; GENETIC SCREENS; KLEBSIELLA; KLEBSIELLA PNEUMONIAE; NUCLEAR FACTOR KAPPAB; SIGNALING PATHWAYS;

BACTERIA;

BACTERIUM LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OUTER MEMBRANE PROTEIN A; PULLULANASE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL PROTEIN; LIPOPOLYSACCHARIDE;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL LOAD; BACTERIAL VIRULENCE; CONTROLLED STUDY; CPS GENE; CYTOKINE RELEASE; ENTC GENE; ENTF GENE; ENVELOPE GENE; ENZYME ACTIVATION; FEMALE; FUNCTIONAL GENOMICS; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENE LOCUS; GENETIC SCREENING; GENOME ANALYSIS; GFP GENE; GLF GENE; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNE EVASION; INTRACELLULAR SIGNALING; IUTA GENE; KC GENE; KLEBSIELLA PNEUMONIAE; MOUSE; NONHUMAN; OMPA GENE; PRIORITY JOURNAL; PSN GENE; PULA GENE; PULC GENE; TNFALPHA GENE; TRANSCRIPTION INITIATION; TRANSPOSON; TYPE II SECRETION SYSTEM; WAAL GENE; WABH GENE; WABK GENE; WABM GENE; YACC GENE; YBTA GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; GENETICS; GENOMICS; IMMUNOLOGY; KLEBSIELLA INFECTION; MICROBIOLOGY; SIGNAL TRANSDUCTION;

KLEBSIELLA; KLEBSIELLA PNEUMONIAE;

ANIMALS; BACTERIAL PROTEINS; FEMALE; GENOMICS; HUMANS; IMMUNE EVASION; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LIPOPOLYSACCHARIDES; MICE; NF-KAPPA B; SIGNAL TRANSDUCTION;

EID: 84936761384     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.621292     Document Type: Article

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