The association between impaired proinsulin processing and type 2 diabetes mellitus in non-obese japanese individuals

Endocrine Journal

Volumn 62, Issue 6, 2015, Pages 485-492

  Katsuta, Hidenori ^a   Ozawa, Sachihiko ^a   Suzuki, Kiyoshi ^b   Takahashi, Kazuto ^a   Tanaka, Toshiaki ^a   Sumitani, Yoshikazu ^a   Nishida, Susumu ^a   Kondo, Takuma ^a   Hosaka, Toshio ^a   Inukai, Kouichi ^a   Ishida, Hitoshi ^a  

^a KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Department of Orthopedic Surgery Shimada Municipal Hospital   (Japan)

Author keywords

HOMA fS; Non obese; Prohormone convertase; Proinsulin processing; Type 2 diabetes

Indexed keywords

CREATININE; IMMUNOREACTIVE INSULIN; PROINSULIN; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; TRIACYLGLYCEROL; BIOLOGICAL MARKER; INSULIN; ISOENZYME; PROINSULIN, DES(31,32)-; SERINE PROTEINASE;

ADULT; AGE; AGED; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; DISEASE MARKER; ENZYME ACTIVITY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HOMEOSTASIS MODEL ASSESSMENT BETA CELL FUNCTION; HUMAN; IMPAIRED GLUCOSE TOLERANCE; JAPANESE (PEOPLE); MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL DISPOSITION INDEX; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PATIENT RISK; PREDICTION; PROTEIN PROCESSING; SENSITIVITY AND SPECIFICITY; SEX; TRIACYLGLYCEROL BLOOD LEVEL; ALGORITHM; BLOOD; COHORT ANALYSIS; DIABETES MELLITUS, TYPE 2; ETHNOLOGY; INSULIN RESISTANCE; JAPAN; METABOLISM; PROTEIN DEGRADATION;

ADULT; AGED; ALGORITHMS; BIOMARKERS; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INSULIN; INSULIN RESISTANCE; ISOENZYMES; JAPAN; MALE; MIDDLE AGED; PROINSULIN; PROPROTEIN CONVERTASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; SENSITIVITY AND SPECIFICITY;

EID: 84936755122     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ14-0611     Document Type: Article

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