Monophosphoryl lipid A inhibits the cytokine response of endothelial cells challenged with LPS

Innate Immunity

Volumn 21, Issue 6, 2015, Pages 565-574

  Stark, Ryan ^a   Choi, Hyehun ^a   Koch, Stephen ^a   Lamb, Fred ^a   Sherwood, Edward ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

endothelial cells; Endotoxin; inflammation; monophosphoryl lipid A; TLR4

Indexed keywords

BETA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHORYL LIPID A; RANTES; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; DRUG COMBINATION; LIPID A; TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 4;

ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CELL DIFFERENTIATION; CLINICAL ASSESSMENT; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DRUG DOSE TITRATION; DRUG MECHANISM; ENDOCYTOSIS; ENDOTOXEMIA; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME MECHANISM; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; POLYMERASE CHAIN REACTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; CELL CULTURE; CYTOLOGY; DOWN REGULATION; DRUG COMBINATION; DRUG EFFECTS; ENDOTHELIUM CELL; IMMUNOLOGY; IMMUNOMODULATION; METABOLISM; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

CELLS, CULTURED; CHEMOKINE CCL5; CHEMOKINE CXCL10; DOWN-REGULATION; DRUG COMBINATIONS; ENDOTHELIAL CELLS; HUMANS; IMMUNITY, INNATE; IMMUNOMODULATION; INTERLEUKIN-6; LIPID A; LIPOPOLYSACCHARIDES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; UMBILICAL VEINS;

EID: 84936135842     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425914564172     Document Type: Article

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