-
1
-
-
4143083577
-
Prior statin therapy is associated with a decreased rate of severe sepsis
-
Almog Y, Shefer A, Novack V, Maimon N, Barski L, Eizinger M, Friger M, Zeller L, Danon A. Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 110: 880-885, 2004.
-
(2004)
Circulation
, vol.110
, pp. 880-885
-
-
Almog, Y.1
Shefer, A.2
Novack, V.3
Maimon, N.4
Barski, L.5
Eizinger, M.6
Friger, M.7
Zeller, L.8
Danon, A.9
-
2
-
-
3843106031
-
Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways
-
Bachar O, Adner M, Uddman R, Cardell LO. Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways. Eur J Immunol 34: 1196-1207, 2004.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1196-1207
-
-
Bachar, O.1
Adner, M.2
Uddman, R.3
Cardell, L.O.4
-
3
-
-
33748525930
-
Multiple roles of Toll-like receptor signaling in atherosclerosis
-
Björkbacka H. Multiple roles of Toll-like receptor signaling in atherosclerosis. Curr Opin Lipidol 17: 527-533, 2006.
-
(2006)
Curr Opin Lipidol
, vol.17
, pp. 527-533
-
-
Björkbacka, H.1
-
4
-
-
19944362471
-
The induction of macrophage gene expression by LPS predominantly utilizes Myd88- independent signaling cascades
-
Björkbacka H, Fitzgerald KA, Huet F, Li X, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW. The induction of macrophage gene expression by LPS predominantly utilizes Myd88- independent signaling cascades. Physiol Genomics 19: 319-330, 2004.
-
(2004)
Physiol Genomics
, vol.19
, pp. 319-330
-
-
Björkbacka, H.1
Fitzgerald, K.A.2
Huet, F.3
Li, X.4
Gregory, J.A.5
Lee, M.A.6
Ordija, C.M.7
Dowley, N.E.8
Golenbock, D.T.9
Freeman, M.W.10
-
5
-
-
3242728901
-
Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways
-
Björkbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, Means T, Halmen K, Luster AD, Golenbock DT, Freeman MW. Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways. Nat Med 10: 416-421, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 416-421
-
-
Björkbacka, H.1
Kunjathoor, V.V.2
Moore, K.J.3
Koehn, S.4
Ordija, C.M.5
Lee, M.A.6
Means, T.7
Halmen, K.8
Luster, A.D.9
Golenbock, D.T.10
Freeman, M.W.11
-
6
-
-
77949519323
-
Carbon monoxide blocks lipopolysaccharide-induced gene expression by interfering with proximal TLR4 to NF-kappaB signal transduction in human monocytes
-
Chhikara M, Wang S, Kern SJ, Ferreyra GA, Barb JJ, Munson PJ, Danner RL. Carbon monoxide blocks lipopolysaccharide-induced gene expression by interfering with proximal TLR4 to NF-kappaB signal transduction in human monocytes. PLos One 4: e8139, 2009.
-
(2009)
PLos One
, vol.4
-
-
Chhikara, M.1
Wang, S.2
Kern, S.J.3
Ferreyra, G.A.4
Barb, J.J.5
Munson, P.J.6
Danner, R.L.7
-
7
-
-
0035574650
-
In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products
-
Diomede L, Albani D, Sottocorno M, Donati MB, Bianchi M, Fruscella P, Salmona M. In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products. Arterioscler Thromb Vasc Biol 21: 1327-1332, 2001.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1327-1332
-
-
Diomede, L.1
Albani, D.2
Sottocorno, M.3
Donati, M.B.4
Bianchi, M.5
Fruscella, P.6
Salmona, M.7
-
8
-
-
0033781454
-
Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology
-
Griendling KK, Sorescu D, Lassegue B, Ushio-Fukai M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 20: 2175-2183, 2000.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2175-2183
-
-
Griendling, K.K.1
Sorescu, D.2
Lassegue, B.3
Ushio-Fukai, M.4
-
9
-
-
0037031061
-
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
-
Heart Protection Study Collaborative Group
-
Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 360: 7-22, 2002.
-
(2002)
Lancet
, vol.360
, pp. 7-22
-
-
-
10
-
-
0037151057
-
Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression
-
Hsu HY, Wen MH. Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression. J Biol Chem 277: 22131-22139, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 22131-22139
-
-
Hsu, H.Y.1
Wen, M.H.2
-
11
-
-
0035928838
-
Immunopathogenesis of atherosclerosis: Endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet
-
Lehr HA, Sagban TA, Ihling C, Zahringer U, Hungerer KD, Blumrich M, Reifenberg K, Bhakdi S. Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet. Circulation 104: 914-920, 2001.
-
(2001)
Circulation
, vol.104
, pp. 914-920
-
-
Lehr, H.A.1
Sagban, T.A.2
Ihling, C.3
Zahringer, U.4
Hungerer, K.D.5
Blumrich, M.6
Reifenberg, K.7
Bhakdi, S.8
-
12
-
-
19644390754
-
Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome
-
Methe H, Kim JO, Kofler S, Weis M, Nabauer M, Koglin J. Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome. Circulation 111: 2654-2661, 2005.
-
(2005)
Circulation
, vol.111
, pp. 2654-2661
-
-
Methe, H.1
Kim, J.O.2
Kofler, S.3
Weis, M.4
Nabauer, M.5
Koglin, J.6
-
13
-
-
0037449723
-
Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells
-
Miller YI, Viriyakosol S, Binder CJ, Feramisco JR, Kirkland TN, Witztum JL. Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells. J Biol Chem 278: 1561-1568, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 1561-1568
-
-
Miller, Y.I.1
Viriyakosol, S.2
Binder, C.J.3
Feramisco, J.R.4
Kirkland, T.N.5
Witztum, J.L.6
-
14
-
-
9644287966
-
Endothelial cell culture: Beginnings of modern vascular biology
-
Nachman RL, Jaffe EA. Endothelial cell culture: beginnings of modern vascular biology. J Clin Invest 114: 1037-1040, 2004.
-
(2004)
J Clin Invest
, vol.114
, pp. 1037-1040
-
-
Nachman, R.L.1
Jaffe, E.A.2
-
15
-
-
33750360916
-
Simvastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo
-
Niessner A, Steiner S, Speidl WS, Pleiner J, Seidinger D, Maurer G, Goronzy JJ, Weyand CM, Kopp CW, Huber K, Wolzt M, Wojta J. Simvastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo. Atherosclerosis 189: 408-413, 2006.
-
(2006)
Atherosclerosis
, vol.189
, pp. 408-413
-
-
Niessner, A.1
Steiner, S.2
Speidl, W.S.3
Pleiner, J.4
Seidinger, D.5
Maurer, G.6
Goronzy, J.J.7
Weyand, C.M.8
Kopp, C.W.9
Huber, K.10
Wolzt, M.11
Wojta, J.12
-
16
-
-
14244266579
-
Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK
-
Nishida S, Matsuoka H, Tsubaki M, Tanimori Y, Yanae M, Fujii Y, Iwaki M. Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK. Mol Cell Biochem 269: 109-114, 2005.
-
(2005)
Mol Cell Biochem
, vol.269
, pp. 109-114
-
-
Nishida, S.1
Matsuoka, H.2
Tsubaki, M.3
Tanimori, Y.4
Yanae, M.5
Fujii, Y.6
Iwaki, M.7
-
17
-
-
9344256068
-
Simvastatin prevents vascular hyporeactivity during inflammation
-
Pleiner J, Schaller G, Mittermayer F, Zorn S, Marsik C, Polterauer S, Kapiotis S, Wolzt M. Simvastatin prevents vascular hyporeactivity during inflammation. Circulation 110: 3349-3354, 2004.
-
(2004)
Circulation
, vol.110
, pp. 3349-3354
-
-
Pleiner, J.1
Schaller, G.2
Mittermayer, F.3
Zorn, S.4
Marsik, C.5
Polterauer, S.6
Kapiotis, S.7
Wolzt, M.8
-
18
-
-
0042190639
-
Low-level endotoxin induces potent inflammatory activation of human blood vessels: Inhibition by statins
-
Rice JB, Stoll LL, Li WG, Denning GM, Weydert J, Charipar E, Richenbacher WE, Miller FJ Jr, Weintraub NL. Low-level endotoxin induces potent inflammatory activation of human blood vessels: inhibition by statins. Arterioscler Thromb Vasc Biol 23: 1576-1582, 2003.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1576-1582
-
-
Rice, J.B.1
Stoll, L.L.2
Li, W.G.3
Denning, G.M.4
Weydert, J.5
Charipar, E.6
Richenbacher, W.E.7
Miller Jr., F.J.8
Weintraub, N.L.9
-
19
-
-
0033538498
-
Inhibition of p38(MAPK) induces low density lipoprotein receptor expression through activation of the p42/44(MAPK) cascade
-
One-way cross-talk between p38(MAPK) and p42/44(MAPK)
-
Singh RP, Dhawan P, Golden C, Kapoor GS, Mehta KD. One-way cross-talk between p38(MAPK) and p42/44(MAPK). Inhibition of p38(MAPK) induces low density lipoprotein receptor expression through activation of the p42/44(MAPK) cascade. J Biol Chem 274: 19593-19600, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 19593-19600
-
-
Singh, R.P.1
Dhawan, P.2
Golden, C.3
Kapoor, G.S.4
Mehta, K.D.5
-
20
-
-
0035081609
-
Lovastatin blocks basic fibroblast growth factor-induced mitogen-activated protein kinase signaling in coronary smooth muscle cells via phosphatase inhibition
-
Skaletz-Rorowski A, Muller JG, Kroke A, Waltenberger J, Pulawski E, Pinkernell K, Breithardt G. Lovastatin blocks basic fibroblast growth factor-induced mitogen-activated protein kinase signaling in coronary smooth muscle cells via phosphatase inhibition. Eur J Cell Biol 80: 207-212, 2001.
-
(2001)
Eur J Cell Biol
, vol.80
, pp. 207-212
-
-
Skaletz-Rorowski, A.1
Muller, J.G.2
Kroke, A.3
Waltenberger, J.4
Pulawski, E.5
Pinkernell, K.6
Breithardt, G.7
-
21
-
-
12444341944
-
Toll-like receptors in innate immunity
-
Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 17: 1-14, 2005.
-
(2005)
Int Immunol
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
22
-
-
19444386649
-
Prediction of siRNA functionality using generalized string kernel and support vector machine
-
Teramoto R, Aoki M, Kimura T, Kanaoka M. Prediction of siRNA functionality using generalized string kernel and support vector machine. FEBS Lett 579: 2878-2882, 2005.
-
(2005)
FEBS Lett
, vol.579
, pp. 2878-2882
-
-
Teramoto, R.1
Aoki, M.2
Kimura, T.3
Kanaoka, M.4
-
23
-
-
0034840966
-
Simvastatin treatment is associated with improvement in coronary endothelial function and decreased cytokine activation in patients after heart transplantation
-
Weis M, Pehlivanli S, Meiser BM, von Scheidt W. Simvastatin treatment is associated with improvement in coronary endothelial function and decreased cytokine activation in patients after heart transplantation. J Am Coll Cardiol 38: 814-818, 2001.
-
(2001)
J Am Coll Cardiol
, vol.38
, pp. 814-818
-
-
Weis, M.1
Pehlivanli, S.2
Meiser, B.M.3
von Scheidt, W.4
-
24
-
-
4644261860
-
Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis
-
Wu J, Wong WW, Khosravi F, Minden MD, Penn LZ. Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis. Cancer Res 64: 6461-6468, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 6461-6468
-
-
Wu, J.1
Wong, W.W.2
Khosravi, F.3
Minden, M.D.4
Penn, L.Z.5
-
25
-
-
0035831516
-
Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase
-
Zhang H, Shi X, Hampong M, Blanis L, Pelech S. Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase. J Biol Chem 276: 6905-6908, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 6905-6908
-
-
Zhang, H.1
Shi, X.2
Hampong, M.3
Blanis, L.4
Pelech, S.5
|