-
1
-
-
0032716031
-
The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors
-
Means, T. K., E. Lien, A. Yoshimura, S. Wang, D. T. Golenbock, and M. J. Fenton. 1999. The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors. J. Immunol. 163:6748.
-
(1999)
J. Immunol.
, vol.163
, pp. 6748
-
-
Means, T.K.1
Lien, E.2
Yoshimura, A.3
Wang, S.4
Golenbock, D.T.5
Fenton, M.J.6
-
2
-
-
0034650427
-
Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex
-
Ohashi, K., V. Burkart, S. Flohe, and H. Kolb. 2000. Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex. J. Immunol. 164:558.
-
(2000)
J. Immunol.
, vol.164
, pp. 558
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
Kolb, H.4
-
3
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
-
Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11:443.
-
(1999)
Immunity
, vol.11
, pp. 443
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
4
-
-
0034650420
-
Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a Toll-like receptor 2- and MyD88-dependent signaling pathway
-
Takeuchi, O., A. Kaufmann, K. Grote, T. Kawai, K. Hoshino, M. Morr, P. F. Muhlradt, and S. Akira. 2000. Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a Toll-like receptor 2- and MyD88-dependent signaling pathway. J. Immunol. 164:554.
-
(2000)
J. Immunol.
, vol.164
, pp. 554
-
-
Takeuchi, O.1
Kaufmann, A.2
Grote, K.3
Kawai, T.4
Hoshino, K.5
Morr, M.6
Muhlradt, P.F.7
Akira, S.8
-
5
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the LPS gene product
-
Hoshino, K., O. Takeuchi, T. Kawai, H. Sanjo, T. Ogawa, Y. Takeda, K. Takeda, and S. Akira. 1999. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the LPS gene product. J. Immunol. 162:3749.
-
(1999)
J. Immunol.
, vol.162
, pp. 3749
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
Takeda, K.7
Akira, S.8
-
6
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones, E. A., L. Popova, L. Kwinn, L. M. Haynes, L. P. Jones, R. A. Tripp, E. E. Walsh, M. W. Freeman, D. T. Golenbock, L. J. Anderson, and R. W. Finberg. 2000. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat. Immunol. 1:398.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 398
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
Haynes, L.M.4
Jones, L.P.5
Tripp, R.A.6
Walsh, E.E.7
Freeman, M.W.8
Golenbock, D.T.9
Anderson, L.J.10
Finberg, R.W.11
-
7
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio, M., J. Ni, P. Feng, and V. M. Dixit. 1997. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278:1612.
-
(1997)
Science
, vol.278
, pp. 1612
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
8
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathway
-
Medzhitov, R., P. Preston-Hurlburt, E. Kopp, A. Stadlen, C. Chen, S. Ghosh, and C. A. Janeway. 1998. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathway. Mol. Cell. Biol. 2:253.
-
(1998)
Mol. Cell. Biol.
, vol.2
, pp. 253
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway, C.A.7
-
9
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., O. Adachi, T. Ogawa, K. Takeda, and S. Akira. 1999. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11:115.
-
(1999)
Immunity
, vol.11
, pp. 115
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
10
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng, T., G. M. Barton, and R. Medzhitov. 2001. TIRAP: An adapter molecule in the Toll signaling pathway. Nat. Immunol. 2:835.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 835
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
11
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald, K. A., E. M. Palsson-McDermott, A. G. Bowie, C. A. Jefferies, A. S. Mansell, G. Brady, E. Brint, A. Dunne, P. Gray, M. T. Harte, et al. 2001. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413:78.
-
(2001)
Nature
, vol.413
, pp. 78
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
-
12
-
-
0035115080
-
Signaling by TLR2 vs. TLR4 agonists results in differential gene expression in murine macrophages
-
Hirschfeld, M., J. J. Weis, V. Toshchakov, C. A. Salkowski, M. J. Cody, D. C. Ward, N. Qureshi, S. M. Michalek, and S. N. Vogel. 2001. Signaling by TLR2 vs. TLR4 agonists results in differential gene expression in murine macrophages. Infect. Immun. 69:2477.
-
(2001)
Infect. Immun.
, vol.69
, pp. 2477
-
-
Hirschfeld, M.1
Weis, J.J.2
Toshchakov, V.3
Salkowski, C.A.4
Cody, M.J.5
Ward, D.C.6
Qureshi, N.7
Michalek, S.M.8
Vogel, S.N.9
-
13
-
-
0036222241
-
TLR4, but not TLR2, mediates IFN-β-induced STAT1 α/β-dependent gene expression in macrophages
-
Toshchakov, V., B. W. Jones, P. Y. Perera, K. Thomas, M. J. Cody, S. Zhang, B. R. Williams, J. Major, T. A. Hamilton, M. J. Fenton, and S. N. Vogel. 2002. TLR4, but not TLR2, mediates IFN-β-induced STAT1 α/β-dependent gene expression in macrophages. Nat. Immunol. 3:392.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 392
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.Y.3
Thomas, K.4
Cody, M.J.5
Zhang, S.6
Williams, B.R.7
Major, J.8
Hamilton, T.A.9
Fenton, M.J.10
Vogel, S.N.11
-
14
-
-
0033215123
-
Human Toll-like receptors mediate cellular activation by M. tuberculosis
-
Means, T. K., S. Wang, E. Lien, A. Yoshimura, D. T. Golenbock, and M. J. Fenton. 1999. Human Toll-like receptors mediate cellular activation by M. tuberculosis. J. Immunol. 163:3920.
-
(1999)
J. Immunol.
, vol.163
, pp. 3920
-
-
Means, T.K.1
Wang, S.2
Lien, E.3
Yoshimura, A.4
Golenbock, D.T.5
Fenton, M.J.6
-
15
-
-
0029590069
-
Deficient signaling in mice devoid of double-stranded, RNA-dependent protein kinase
-
Yang, Y. L., L. F. Reis, J. Pavlovic, A. Aguzzi, R. Schafer, A. Kumar, B. R. Williams, M. Aguet, and C. Weissmann. 1995. Deficient signaling in mice devoid of double-stranded, RNA-dependent protein kinase. EMBO J. 14:6095.
-
(1995)
EMBO J.
, vol.14
, pp. 6095
-
-
Yang, Y.L.1
Reis, L.F.2
Pavlovic, J.3
Aguzzi, A.4
Schafer, R.5
Kumar, A.6
Williams, B.R.7
Aguet, M.8
Weissmann, C.9
-
16
-
-
0030722706
-
Modulation of interleukin 1β production in macrophages stimulated with lipopolysaccharide by the protein kinase inhibitor staurosporine
-
Schilling, D., J. Brauburger, W. Ruiner, and K. Nixdorff. 1997. Modulation of interleukin 1β production in macrophages stimulated with lipopolysaccharide by the protein kinase inhibitor staurosporine. J. Endotoxin Res. 4:251.
-
(1997)
J. Endotoxin Res.
, vol.4
, pp. 251
-
-
Schilling, D.1
Brauburger, J.2
Ruiner, W.3
Nixdorff, K.4
-
17
-
-
0036060104
-
Negative regulation of IL-1β production at the level of transcription in macrophages stimulated with LPS
-
Schilling, D., T. Beissert, M. J. Fenton, and K. Nixdorff. 2001. Negative regulation of IL-1β production at the level of transcription in macrophages stimulated with LPS. Cytokine 16:51.
-
(2001)
Cytokine
, vol.16
, pp. 51
-
-
Schilling, D.1
Beissert, T.2
Fenton, M.J.3
Nixdorff, K.4
-
18
-
-
0027292176
-
Differential modulation of the effects of lipopolysaccharide on macrophages by a major outer membrane protein of Proteus mirabilis
-
Weber, G., F. Link, E. Ferber, P. G. Munder, D. Zeitter, R. R. Bartlett, and K. Nixdorff. 1993. Differential modulation of the effects of lipopolysaccharide on macrophages by a major outer membrane protein of Proteus mirabilis. J. Immunol. 151:415.
-
(1993)
J. Immunol.
, vol.151
, pp. 415
-
-
Weber, G.1
Link, F.2
Ferber, E.3
Munder, P.G.4
Zeitter, D.5
Bartlett, R.R.6
Nixdorff, K.7
-
19
-
-
0021360012
-
Acyltransferase-catalyzed cleavage of arachidonic acid from phospholipids and transfer to lysophosphatides in macrophages derived from bone marrow: Comparison of different donor- and acceptor substrate combinations
-
Flesch, I., B. Ecker, and E. Ferber. 1984. Acyltransferase-catalyzed cleavage of arachidonic acid from phospholipids and transfer to lysophosphatides in macrophages derived from bone marrow: Comparison of different donor- and acceptor substrate combinations. Eur. J. Biochem. 139:431.
-
(1984)
Eur. J. Biochem.
, vol.139
, pp. 431
-
-
Flesch, I.1
Ecker, B.2
Ferber, E.3
-
20
-
-
0034662239
-
Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine Toll-like receptor 2
-
Hirschfeld, M., Y. Ma, J. H. Weis, S. N. Vogel, and J. J. Weis. 2000. Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine Toll-like receptor 2. J. Immunol. 165:618.
-
(2000)
J. Immunol.
, vol.165
, pp. 618
-
-
Hirschfeld, M.1
Ma, Y.2
Weis, J.H.3
Vogel, S.N.4
Weis, J.J.5
-
21
-
-
0034976848
-
Different Toll-like receptor agonists induce distinct macrophage responses
-
Jones, B. W., T. K. Means, K. A. Heldwein, M. A. Keen, P. J. Hill, J. T. Belisle, and M. J. Fenton. 2001. Different Toll-like receptor agonists induce distinct macrophage responses. J. Leukocyte Biol. 69:1036.
-
(2001)
J. Leukocyte Biol.
, vol.69
, pp. 1036
-
-
Jones, B.W.1
Means, T.K.2
Heldwein, K.A.3
Keen, M.A.4
Hill, P.J.5
Belisle, J.T.6
Fenton, M.J.7
-
23
-
-
0035173628
-
CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and Taxol-inducible gene expression
-
Perera, P.-Y., T. N. Mayadas, O. Takeuchi, S. Akira, M. Zaks-Zilberman, S. M. Goyert, and S. N. Vogel. 2001. CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and Taxol-inducible gene expression. J. Immunol. 166:574.
-
(2001)
J. Immunol.
, vol.166
, pp. 574
-
-
Perera, P.-Y.1
Mayadas, T.N.2
Takeuchi, O.3
Akira, S.4
Zaks-Zilberman, M.5
Goyert, S.M.6
Vogel, S.N.7
-
24
-
-
0028324655
-
Taxol provides a second signal for murine macrophage tumoricidal activity
-
Manthey, C. L., P.-Y. Perera, C. A. Salkowski, and S. N. Vogel. 1994. Taxol provides a second signal for murine macrophage tumoricidal activity. J. Immunol. 152:825.
-
(1994)
J. Immunol.
, vol.152
, pp. 825
-
-
Manthey, C.L.1
Perera, P.-Y.2
Salkowski, C.A.3
Vogel, S.N.4
-
25
-
-
0028285885
-
Gram-positive cell walls stimulate synthesis of tumor necrosis factor α and interleukin-6 by human monocytes
-
Heumann, D., C. Barras, A. Severin, M. P. Glauser, and A. Tomasz. 1994. Gram-positive cell walls stimulate synthesis of tumor necrosis factor α and interleukin-6 by human monocytes. Infect. Immun. 62:2715.
-
(1994)
Infect. Immun.
, vol.62
, pp. 2715
-
-
Heumann, D.1
Barras, C.2
Severin, A.3
Glauser, M.P.4
Tomasz, A.5
-
26
-
-
0028940959
-
Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages
-
Radolf, J. D., L. L. Arndt, D. R. Akins, L. L. Curetty, M. E. Levi, Y. Shen, L. S. Davis, and M. V. Norgard. 1995. Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages. J. Immunol. 154:2866.
-
(1995)
J. Immunol.
, vol.154
, pp. 2866
-
-
Radolf, J.D.1
Arndt, L.L.2
Akins, D.R.3
Curetty, L.L.4
Levi, M.E.5
Shen, Y.6
Davis, L.S.7
Norgard, M.V.8
-
27
-
-
0037022296
-
Human macrophage activation programs induced by bacterial pathogens
-
Nau, G. J., J. F. Richmond, A. Schlesinger, E. G. Jennings, E. S. Lander, and R. A. Young. 2002. Human macrophage activation programs induced by bacterial pathogens. Proc. Natl. Acad. Sci. USA 99:1503.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1503
-
-
Nau, G.J.1
Richmond, J.F.2
Schlesinger, A.3
Jennings, E.G.4
Lander, E.S.5
Young, R.A.6
-
28
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors
-
Ozinsky, A., D. M. Underhill, J. D. Fontenot, A. M. Hajjar, K. D. Smith, C. B. Wilson, L. Schroeder, and A. Aderem. 2000. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors. Proc. Natl. Acad. Sci. USA 97:13766.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13766
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
Hajjar, A.M.4
Smith, K.D.5
Wilson, C.B.6
Schroeder, L.7
Aderem, A.8
-
29
-
-
0035879283
-
Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling
-
Bulut, Y., E. Faure, L. Thomas, O. Equils, and M. Arditi. 2001. Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. J. Immunol. 167:987.
-
(2001)
J. Immunol.
, vol.167
, pp. 987
-
-
Bulut, Y.1
Faure, E.2
Thomas, L.3
Equils, O.4
Arditi, M.5
-
30
-
-
0036644042
-
Cutting edge: Role of toll-like receptor I in mediating immune response to microbial lipoproteins
-
2002
-
Takeuchi, O., S. Sato, T. Horiuchi, K. Hoshino, K. Takeda, Z. Dong, R. L. Modlin, and S. Akira. 2002. 2002. Cutting edge: role of toll-like receptor I in mediating immune response to microbial lipoproteins. J. Immunol. 169:10.
-
(2002)
J. Immunol.
, vol.169
, pp. 10
-
-
Takeuchi, O.1
Sato, S.2
Horiuchi, T.3
Hoshino, K.4
Takeda, K.5
Dong, Z.6
Modlin, R.L.7
Akira, S.8
-
31
-
-
0033861419
-
The interleukin-1 receptor/Toll-like receptor superfamily: Signal generators for pro-inflammatory interleukins and microbial products
-
Bowie, A., and L. A. O'Neill. 2000. The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products. J. Leukocyte Biol. 67:508.
-
(2000)
J. Leukocyte Biol.
, vol.67
, pp. 508
-
-
Bowie, A.1
O'Neill, L.A.2
-
32
-
-
0025311336
-
Interleukin-6 production by murine macrophage cell lines P388D1 and J774A.1: Stimulation requirements and kinetics
-
Martin, C. A., and M. E. Dorf. 1990. Interleukin-6 production by murine macrophage cell lines P388D1 and J774A.1: stimulation requirements and kinetics. Cell. Immunol. 128:555.
-
(1990)
Cell. Immunol.
, vol.128
, pp. 555
-
-
Martin, C.A.1
Dorf, M.E.2
-
33
-
-
0028362019
-
Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide
-
Dendorfer, U., P. Oettgen, and T. A. Libermann. 1994. Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide. Mol. Cell. Biol. 14:4443.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4443
-
-
Dendorfer, U.1
Oettgen, P.2
Libermann, T.A.3
|