Understanding the Molecular Basis for Differences in Responses of Fish Estrogen Receptor Subtypes to Environmental Estrogens

Environmental Science and Technology

Volumn 49, Issue 12, 2015, Pages 7439-7447

  Tohyama, Saki ^a,b   Miyagawa, Shinichi ^b   Lange, Anke ^c   Ogino, Yukiko ^b   Mizutani, Takeshi ^b   Tatarazako, Norihisa ^d   Katsu, Yoshinao ^e   Ihara, Masaru ^f   Tanaka, Hiroaki ^f   Ishibashi, Hiroshi ^g   Kobayashi, Tohru ^a   Tyler, Charles R ^c   Iguchi, Taisen ^b  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^c UNIVERSITY OF EXETER   (United Kingdom)

^d NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^e HOKKAIDO UNIVERSITY   (Japan)

^f KYOTO UNIVERSITY   (Japan)

^g EHIME UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FISH; PIGMENTS; PROTEINS;

BASIC AND APPLIED RESEARCH; ENDOCRINE DISRUPTING CHEMICALS; ENVIRONMENTAL ESTROGENS; ESTROGEN RECEPTOR; REPORTER GENE ASSAYS; RESPONSE PATTERNS; SEXUAL DIFFERENTIATIONS; SIGNALING PATHWAYS;

ENDOCRINE DISRUPTERS;

4 NONYLPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; CHIMERIC PROTEIN; CHLORPHENOTANE; ENDOCRINE DISRUPTOR; ESTROGEN DERIVATIVE; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR 2A; ESTROGEN RECEPTOR 2B; ESTROGEN RECEPTOR ALPHA; HYBRID PROTEIN; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; 4-NONYLPHENOL; AMINO ACID; BENZHYDRYL DERIVATIVE; ESTRADIOL; ESTROGEN; LIGAND; O,P'-DDT; PHENOL DERIVATIVE; POLLUTANT;

ASSAY; CHEMICAL POLLUTANT; DDT; ENDOCRINE DISRUPTOR; ESTROGENIC COMPOUND; GENE EXPRESSION; MOLECULAR ANALYSIS; POLLUTION EXPOSURE; PROTEIN; SEX HORMONE; TELEOST;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FISH; HORMONE RESPONSE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING; NONHUMAN; QUANTITATIVE ANALYSIS; REPORTER GENE; SIGNAL TRANSDUCTION; TELEOST; TRANSACTIVATION ASSAY; ANIMAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; COMPUTER SIMULATION; COS 1 CELL LINE; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR CLONING; ORYZIAS; PHYLOGENY; POLLUTANT; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; TOXICITY; TRANSCRIPTION INITIATION;

TELEOSTEI;

AMINO ACIDS; ANIMALS; BENZHYDRYL COMPOUNDS; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COMPUTER SIMULATION; COS CELLS; DDT; ENDOCRINE DISRUPTORS; ENVIRONMENTAL POLLUTANTS; ESTRADIOL; ESTROGENS; HEK293 CELLS; HUMANS; LIGANDS; ORYZIAS; PHENOLS; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, ESTROGEN; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84934991525     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/acs.est.5b00704     Document Type: Article

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