A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor β

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 26, 2006, Pages 9908-9911

  Wang, Yong ^a   Chirgadze, Nickolay Y ^a   Briggs, Stephen L ^a   Khan, Sohaib ^b   Jensen, Elwood V ^b   Burris, Thomas P ^a,c  

^a ELI LILLY AND COMPANY   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antiestrogen; Crystallography; Nuclear receptor

Indexed keywords

ANTIESTROGEN; ESTROGEN RECEPTOR BETA; HYDROXYTAMOXIFEN;

ARTICLE; BIOCHEMISTRY; CRYSTAL STRUCTURE; DRUG BINDING SITE; ESTROGEN ACTIVITY; HUMAN; LIGAND BINDING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ANALYSIS; SURFACE PROPERTY;

ANTINEOPLASTIC AGENTS, HORMONAL; BINDING SITES; CRYSTALLOGRAPHY; ESTROGEN RECEPTOR BETA; HUMANS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; TAMOXIFEN;

EID: 33745632097     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510596103     Document Type: Article

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