Differing species responsiveness of estrogenic contaminants in fish is conferred by the ligand binding domain of the estrogen receptor

Environmental Science and Technology

Volumn 48, Issue 9, 2014, Pages 5254-5263

  Miyagawa, Shinichi ^a   Lange, Anke ^b   Hirakawa, Ikumi ^a,c,d   Tohyama, Saki ^a,e   Ogino, Yukiko ^a   Mizutani, Takeshi ^a   Kagami, Yoshihiro ^c   Kusano, Teruhiko ^c   Ihara, Masaru ^f   Tanaka, Hiroaki ^f   Tatarazako, Norihisa ^g   Ohta, Yasuhiko ^d   Katsu, Yoshinao ^h   Tyler, Charles R ^b   Iguchi, Taisen ^a  

^a OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

^b UNIVERSITY OF EXETER   (United Kingdom)

^c Ecogenomics Inc   (Japan)

^d YAMAGUCHI UNIVERSITY   (Japan)

^e UNIVERSITY OF SHIZUOKA   (Japan)

^f KYOTO UNIVERSITY   (Japan)

^g NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^h HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FISH; LIGANDS; ORGANIC POLLUTANTS; RISK ASSESSMENT;

ENDOCRINE DISRUPTING CHEMICALS; ENVIRONMENTAL ESTROGENS; ENVIRONMENTAL RISK ASSESSMENT; ESTROGENIC CHEMICALS; ESTROGENIC CONTAMINANTS; LIGAND BINDING DOMAIN; REPORTER GENE ASSAYS; REPRODUCTIVE DEVELOPMENT;

ENDOCRINE DISRUPTERS;

4 OCTYLPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; CHLORPHENOTANE; DIETHYLSTILBESTROL; ENDOCRINE DISRUPTOR; EQUILIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; METHIONINE; NONYLPHENOL; TRICLOSAN;

BIOACCUMULATION; CHEMICAL BINDING; ECOTOXICOLOGY; ENVIRONMENTAL RISK; ESTROGENIC COMPOUND; GENE EXPRESSION; LIGAND; POLLUTION EXPOSURE; RISK ASSESSMENT; TELEOST;

ARTICLE; CONTROLLED STUDY; FISH; GUPPY; HEK293 CELL LINE; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; PHYLOGENETIC TREE; REPORTER GENE; RISK ASSESSMENT;

ANIMALS; ENDOCRINE DISRUPTORS; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FISHES; GENES, REPORTER; LIGANDS; PROTEIN STRUCTURE, TERTIARY; SPECIES SPECIFICITY; TRANSCRIPTIONAL ACTIVATION; WATER POLLUTANTS, CHEMICAL;

EID: 84899853274     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es5002659     Document Type: Article

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