Low and moderate doses of ionizing radiation up to 2 Gy modulate transmigration and chemotaxis of activated macrophages, provoke an anti-inflammatory cytokine milieu, but do not impact upon viability and phagocytic function

Clinical and Experimental Immunology

Volumn 179, Issue 1, 2015, Pages 50-61

  Wunderlich, R ^a   Ernst, A ^b   Rodel F ^c   Fietkau, R ^a   Ott, O ^a   Lauber, K ^b   Frey, B ^a   Gaipl, U S ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

Chemotaxis; Cytokines; Inflammation; Macrophage; Phagocytosis

Indexed keywords

CYTOKINE; DOXORUBICIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA; AUTACOID;

ADHERENT CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL DEATH; CELL VIABILITY; CHEMOTAXIS; COLORECTAL TUMOR; CONTROLLED STUDY; CYTOKINE RELEASE; DNA CONTENT; EX VIVO STUDY; HUMAN; IMMUNOMODULATION; INFLAMMATORY DISEASE; IONIZING RADIATION; MACROPHAGE ACTIVATION; MACROPHAGE MIGRATION; MICROENVIRONMENT; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION PROTECTION; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; TUMOR CELL; WESTERN BLOTTING; X IRRADIATION; ANIMAL; CELL SURVIVAL; DISEASE MODEL; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; METABOLISM; PROTEIN TRANSPORT; RADIATION RESPONSE; X RAY;

ANIMALS; CELL SURVIVAL; CHEMOTAXIS; CYTOKINES; DISEASE MODELS, ANIMAL; INFLAMMATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE; PHAGOCYTOSIS; PROTEIN TRANSPORT; RADIATION, IONIZING; TRANSCRIPTION FACTOR RELA; X-RAYS;

EID: 84934943164     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12344     Document Type: Article

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